Published in Oxid Med Cell Longev on February 05, 2016
Bisphenol A induces hepatotoxicity through oxidative stress in rat model. Oxid Med Cell Longev (2012) 1.02
Doxorubicin toxicity can be ameliorated during antioxidant L-carnitine supplementation. Oxid Med Cell Longev (2010) 0.95
Thymoquinone improves aging-related endothelial dysfunction in the rat mesenteric artery. Naunyn Schmiedebergs Arch Pharmacol (2012) 0.88
Intestinal, airway, and cardiovascular relaxant activities of thymoquinone. Evid Based Complement Alternat Med (2012) 0.85
Protective effect of rutin on the antioxidant genes expression in hypercholestrolemic male Westar rat. BMC Complement Altern Med (2013) 0.84
The protective effect of Nigella sativa against liver injury: a review. Iran J Basic Med Sci (2014) 0.81
Downregulation of oxidative and nitrosative apoptotic signaling by L-carnitine in Ifosfamide-induced Fanconi syndrome rat model. Oxid Med Cell Longev (2012) 0.78
Effects of Nigella sativa oil extract on inflammatory cytokine response and oxidative stress status in patients with rheumatoid arthritis: a randomized, double-blind, placebo-controlled clinical trial. Avicenna J Phytomed (2016) 0.78
In vivo modulation of iNOS pathway in hepatocellular carcinoma by Nigella sativa. Environ Health Prev Med (2013) 0.76
Inflammation, oxidative stress and apoptosis cascade implication in bisphenol A-induced liver fibrosis in male rats. Int J Exp Pathol (2016) 0.75
Gastrointestinal effects of Nigella sativa and its main constituent, thymoquinone: a review. Avicenna J Phytomed (2016) 0.75
Thymoquinone ameliorates lead-induced suppression of the antioxidant system in rat kidneys. Libyan J Med (2016) 0.75
Experimental Hepatic Carcinogenesis: Oxidative Stress and Natural Antioxidants. Open Access Maced J Med Sci (2017) 0.75
Thymoquinone, as an anticancer molecule: from basic research to clinical investigation. Oncotarget (2017) 0.75
Cancer statistics, 2009. CA Cancer J Clin (2009) 83.57
Tissue sulfhydryl groups. Arch Biochem Biophys (1959) 61.89
Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem (1979) 41.65
Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. J Biol Chem (1974) 27.82
Hepatocellular carcinoma pathogenesis: from genes to environment. Nat Rev Cancer (2006) 10.05
A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples. Biotechniques (1993) 9.61
A rapid, simple spectrophotometric method for simultaneous detection of nitrate and nitrite. Nitric Oxide (2001) 6.48
Glutathione peroxidase activity in selenium-deficient rat liver. Biochem Biophys Res Commun (1976) 5.74
Anticancer potential of curcumin: preclinical and clinical studies. Anticancer Res (2003) 5.72
Importance of Se-glutathione peroxidase, catalase, and Cu/Zn-SOD for cell survival against oxidative stress. Free Radic Biol Med (1994) 2.69
Intervention studies on cancer. Eur J Cancer Prev (1999) 1.70
Nigella sativa thymoquinone-rich fraction greatly improves plasma antioxidant capacity and expression of antioxidant genes in hypercholesterolemic rats. Free Radic Biol Med (2009) 1.46
Natural inhibitors of carcinogenesis. Planta Med (2004) 1.43
Protective effect of thymoquinone against doxorubicin-induced cardiotoxicity in rats: a possible mechanism of protection. Pharmacol Res (2000) 1.37
Antiproliferative activities of citrus flavonoids against six human cancer cell lines. J Agric Food Chem (2002) 1.33
Protective role of Vitamin E pre-treatment on N-nitrosodiethylamine induced oxidative stress in rat liver. Chem Biol Interact (2005) 1.30
Oxidative stress and antioxidant defense mechanisms linked to exercise during cardiopulmonary and metabolic disorders. Oxid Med Cell Longev (2010) 1.26
Thymoquinone ameliorates the nephrotoxicity induced by cisplatin in rodents and potentiates its antitumor activity. Can J Physiol Pharmacol (1997) 1.24
Acetone extract of Angelica sinensis inhibits proliferation of human cancer cells via inducing cell cycle arrest and apoptosis. Life Sci (2004) 1.16
Potential chemoprevention of diethylnitrosamine-initiated and 2-acetylaminofluorene-promoted hepatocarcinogenesis by zerumbone from the rhizomes of the subtropical ginger (Zingiber zerumbet). Chem Biol Interact (2010) 1.12
Nitric oxide and some nitric oxide donor compounds enhance the cytotoxicity of cisplatin. Nitric Oxide (1997) 1.11
Inhibitory effects of thymoquinone against 20-methylcholanthrene-induced fibrosarcoma tumorigenesis. Cancer Detect Prev (2001) 1.10
Inhibition of benzo(a)pyrene-induced forestomach carcinogenesis in mice by thymoquinone. Eur J Cancer Prev (1999) 1.09
Paeoniae Radix, a Chinese herbal extract, inhibit hepatoma cells growth by inducing apoptosis in a p53 independent pathway. Life Sci (2002) 1.08
Thymoquinone protects against carbon tetrachloride hepatotoxicity in mice via an antioxidant mechanism. Biochem Mol Biol Int (1999) 1.06
Suppression of N-nitrosodiethylamine induced hepatocarcinogenesis by silymarin in rats. Chem Biol Interact (2006) 1.05
Ursolic acid attenuates oxidative stress-mediated hepatocellular carcinoma induction by diethylnitrosamine in male Wistar rats. Asian Pac J Cancer Prev (2009) 1.04
Protective role of Apigenin on the status of lipid peroxidation and antioxidant defense against hepatocarcinogenesis in Wistar albino rats. Phytomedicine (2004) 1.01
Thymoquinone supplementation prevents the development of gentamicin-induced acute renal toxicity in rats. Clin Exp Pharmacol Physiol (2007) 1.00
Progression of diethylnitrosamine-induced hepatic carcinogenesis in carnitine-depleted rats. World J Gastroenterol (2009) 0.99
Attenuation of N-nitrosodiethylamine-induced hepatocellular carcinogenesis by a novel flavonol-Morin. Chem Biol Interact (2007) 0.98
Thymoquinone supplementation induces quinone reductase and glutathione transferase in mice liver: possible role in protection against chemical carcinogenesis and toxicity. Phytother Res (2009) 0.95
Stable phenotypic expression of glutathione S-transferase placental type and unstable phenotypic expression of gamma-glutamyltransferase in rat liver preneoplastic and neoplastic lesions. Carcinogenesis (1988) 0.95
Potential chemoprevention of N-nitrosodiethylamine-induced hepatocarcinogenesis by polyphenolics from Acacia nilotica bark. Chem Biol Interact (2009) 0.91
Effects of crude extracts of Agaricus blazei on DNA damage and on rat liver carcinogenesis induced by diethylnitrosamine. Genet Mol Res (2003) 0.90
[Hepatocellular carcinoma]. Pathol Biol (Paris) (1999) 0.90
Study on mechanism of multistep hepatotumorigenesis in rat: development of hepatotumorigenesis. J Vet Sci (2001) 0.89
Chemo-preventive effect of Star anise in N-nitrosodiethylamine initiated and phenobarbital promoted hepato-carcinogenesis. Chem Biol Interact (2007) 0.88
Polymorphonuclear leukocyte species differences in the disposal of hydrogen peroxide (H2O2). Proc Soc Exp Biol Med (1978) 0.87
Nitric oxide synthase inhibitor suppresses the ototoxic side effect of cisplatin in guinea pigs. Anticancer Drugs (2000) 0.87
Inhibition of reactive oxygen species and pre-neoplastic lesions by quercetin through an antioxidant defense mechanism. Free Radic Res (2009) 0.86
Chemopreventive effect of garlic powder diet in diethylnitrosamine-induced rat hepatocarcinogenesis. Life Sci (2003) 0.85
N-Nitrosamines. Occup Med (2000) 0.85
Preventive effect of Ganfujian granule on experimental hepatocarcinoma in rats. World J Gastroenterol (2004) 0.85
Chemopreventive effect of bacoside A on N-nitrosodiethylamine-induced hepatocarcinogenesis in rats. J Cancer Res Clin Oncol (2009) 0.84
Lipid peroxidation and antioxidant status in head and neck squamous cell carcinoma patients. Oxid Med Cell Longev (2010) 0.84
Selenium in the prevention and treatment of hepatocellular carcinoma. Anticancer Agents Med Chem (2010) 0.82
Worker exposures to nitrosamines in a rubber vehicle sealing plant. Am Ind Hyg Assoc J (1996) 0.82
Acceleration of N-nitrosation reactions by electrophiles. IARC Sci Publ (1991) 0.80
Mechanism of gamma-glutamyl transpeptidase release in serum during intrahepatic and extrahepatic cholestasis in the rat: a histochemical, biochemical and molecular approach. Hepatology (1990) 0.80
Publicly funded pegylated interferon-alpha treatment in British Columbia: disparities in treatment patterns for people with hepatitis C. Can J Gastroenterol (2008) 0.78
Tumor promotion by copper-overloading and its enhancement by excess iron accumulation involving oxidative stress responses in the early stage of a rat two-stage hepatocarcinogenesis model. Chem Biol Interact (2010) 0.78
Recombinant bovine pancreatic trypsin inhibitor protects the liver from carbon tetrachloride-induced acute injury in mice. J Pharm Pharmacol (2010) 0.76