Treatment options for patients with triple-negative breast cancer.

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Published in J Hematol Oncol on October 27, 2010

Authors

Rafael Santana-Davila1, Edith A Perez

Author Affiliations

1: Division of Hematology and Oncology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, Florida, 32224, USA.

Associated clinical trials:

I-SPY 2 TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer (I-SPY 2) | NCT01042379

Bicalutamide in Treating Patients With Metastatic Breast Cancer | NCT00468715

A Phase 3, Multi-Center Study of Gemcitabine/Carboplatin, With or Without BSI-201, in Patients With ER-, PR-, and Her2-Negative Metastatic Breast Cancer | NCT00938652

Cediranib Maleate and Olaparib in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Peritoneal Cancer or Recurrent Triple-Negative Breast Cancer | NCT01116648

Paclitaxel With or Without Carboplatin and/or Bevacizumab Followed by Doxorubicin and Cyclophosphamide in Treating Patients With Breast Cancer That Can Be Removed by Surgery | NCT00861705

BEATRICE Study: A Study of Bevacizumab (Avastin) Adjuvant Therapy in Triple Negative Breast Cancer | NCT00528567

Open Label Study to Assess Efficacy and Safety of Olaparib in Confirmed Genetic BRCA1 or BRCA2 Mutation Pats | NCT01078662

A Phase 2 Study of Standard Chemotherapy Plus BSI-201 (a PARP Inhibitor) in the Neoadjuvant Treatment of Triple Negative Breast Cancer | NCT00813956

Study to Assess the Safety and Tolerability of a PARP Inhibitor in Combination With Carboplatin and/or Paclitaxel | NCT00516724

Veliparib, Cisplatin, and Vinorelbine Ditartrate in Treating Patients With Recurrent and/or Metastatic Breast Cancer | NCT01104259

Cisplatin and Paclitaxel With or Without Everolimus in Treating Patients With Stage II or Stage III Breast Cancer | NCT00930930

NCT00647062

Veliparib With or Without Carboplatin in Treating Patients With Stage III-IV Breast Cancer | NCT01149083

Two Regimens of SAR240550/Weekly Paclitaxel and Paclitaxel Alone as Neoadjuvant Therapy in Triple Negative Breast Cancer Patients (SOLTI NEOPARP) | NCT01204125

Triple Negative Breast Cancer Trial (TNT) | NCT00532727

A Study Evaluating INIPARIB in Combination With Chemotherapy to Treat Triple Negative Breast Cancer Brain Metastasis | NCT01173497

Personalized Treatment Selection for Metastatic Breast Cancer | NCT00780676

Selective Neoadjuvant Treatment According to Immunohistochemical Subtype for HER2 Negative Breast Cancer Patients | NCT00432172

Neoadjuvant Sunitinib With Paclitaxel/Carboplatin in Patients With Triple-Negative Breast Cancer | NCT00887575

Panitumumab, Gemcitabine and Carboplatin in Triple-Negative Metastatic Breast Cancer | NCT00894504

Erlotinib Plus Chemotherapy for Treatment of Triple Negative Breast Cancer | NCT00491816

Trial of RAD001 in Triple Negative Metastatic Breast Cancer | NCT00827567

Safety and Efficacy of TKI258 in FGFR1 Amplified and Non-amplified Metastatic HER2 Negative Breast Cancer | NCT00958971

Platinum for Triple-Negative Metastatic Breast Cancer and Evaluation of p63/p73 as a Biomarker of Response | NCT00483223

NCT01115829

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