Published in Eur J Haematol on January 11, 2011
Pivotal role of mTOR signaling in hepatocellular carcinoma. Gastroenterology (2008) 4.03
Frequent inactivation of the tumor suppressor Kruppel-like factor 6 (KLF6) in hepatocellular carcinoma. Hepatology (2004) 2.29
Liver transplantation for hepatocellular carcinoma: extension of indications based on molecular markers. J Hepatol (2008) 2.22
A germline DNA polymorphism enhances alternative splicing of the KLF6 tumor suppressor gene and is associated with increased prostate cancer risk. Cancer Res (2005) 2.02
Downregulation of KLF6 is an early event in hepatocarcinogenesis, and stimulates proliferation while reducing differentiation. J Hepatol (2006) 1.98
Mutations in capillary morphogenesis gene-2 result in the allelic disorders juvenile hyaline fibromatosis and infantile systemic hyalinosis. Am J Hum Genet (2003) 1.86
Targeted inhibition of the KLF6 splice variant, KLF6 SV1, suppresses prostate cancer cell growth and spread. Cancer Res (2005) 1.65
Kruppel-like factor 6 (KLF6) is a tumor-suppressor gene frequently inactivated in colorectal cancer. Gastroenterology (2004) 1.59
Loss of MMP-2 disrupts skeletal and craniofacial development and results in decreased bone mineralization, joint erosion and defects in osteoblast and osteoclast growth. Hum Mol Genet (2007) 1.56
A critical re-appraisal of BRCA1 methylation studies in ovarian cancer. Gynecol Oncol (2010) 1.56
Roles of KLF6 and KLF6-SV1 in ovarian cancer progression and intraperitoneal dissemination. Clin Cancer Res (2006) 1.51
KLF6-SV1 overexpression accelerates human and mouse prostate cancer progression and metastasis. J Clin Invest (2008) 1.36
Myosin IIA associates with NK cell lytic granules to enable their interaction with F-actin and function at the immunological synapse. J Immunol (2009) 1.36
Ras promotes growth by alternative splicing-mediated inactivation of the KLF6 tumor suppressor in hepatocellular carcinoma. Gastroenterology (2008) 1.21
Regulation of Kruppel-like factor 6 tumor suppressor activity by acetylation. Cancer Res (2005) 1.20
Functional inactivation of the KLF6 tumor suppressor gene by loss of heterozygosity and increased alternative splicing in glioblastoma. Int J Cancer (2007) 1.17
The role of KLF6 and its splice variants in cancer therapy. Drug Resist Updat (2008) 1.13
A functional role for KLF6-SV1 in lung adenocarcinoma prognosis and chemotherapy response. Cancer Res (2008) 1.12
Hyaline fibromatosis syndrome inducing mutations in the ectodomain of anthrax toxin receptor 2 can be rescued by proteasome inhibitors. EMBO Mol Med (2011) 1.08
Targeting the FOXO1/KLF6 axis regulates EGFR signaling and treatment response. J Clin Invest (2012) 1.04
Targeting PI3K/AKT/mTOR network for treatment of leukemia. Cell Mol Life Sci (2015) 1.04
Suppression of glioblastoma tumorigenicity by the Kruppel-like transcription factor KLF6. Oncogene (2004) 1.02
KLF6-SV1 is a novel antiapoptotic protein that targets the BH3-only protein NOXA for degradation and whose inhibition extends survival in an ovarian cancer model. Cancer Res (2009) 1.00
Nucleo-cytoplasmic localization domains regulate Krüppel-like factor 6 (KLF6) protein stability and tumor suppressor function. PLoS One (2010) 0.99
Phosphorylation of the myosin IIA tailpiece regulates single myosin IIA molecule association with lytic granules to promote NK-cell cytotoxicity. Blood (2011) 0.97
A candidate chimeric mammalian mRNA transcript is derived from distinct chromosomes and is associated with nonconsensus splice junction motifs. DNA Cell Biol (2003) 0.96
Decreased levels of serum glutathione peroxidase 3 are associated with papillary serous ovarian cancer and disease progression. J Ovarian Res (2011) 0.95
Primate genome gain and loss: a bone dysplasia, muscular dystrophy, and bone cancer syndrome resulting from mutated retroviral-derived MTAP transcripts. Am J Hum Genet (2012) 0.93
Loss of matrix metalloproteinase-2 amplifies murine toxin-induced liver fibrosis by upregulating collagen I expression. Dig Dis Sci (2010) 0.93
Increased alternative splicing of the KLF6 tumour suppressor gene correlates with prognosis and tumour grade in patients with pancreatic cancer. Eur J Cancer (2008) 0.93
Mutation of membrane type-1 metalloproteinase, MT1-MMP, causes the multicentric osteolysis and arthritis disease Winchester syndrome. Am J Hum Genet (2012) 0.91
STK11 domain XI mutations: candidate genetic drivers leading to the development of dysplastic polyps in Peutz-Jeghers syndrome. Hum Mutat (2014) 0.90
Infantile systemic hyalinosis: Case report and review of the literature. J Am Acad Dermatol (2008) 0.89
New clinico-genetic classification of trichothiodystrophy. Am J Med Genet A (2009) 0.88
Systemic hyalinosis mutations in the CMG2 ectodomain leading to loss of function through retention in the endoplasmic reticulum. Hum Mutat (2009) 0.88
A novel matrix metalloproteinase 2 (MMP2) terminal hemopexin domain mutation in a family with multicentric osteolysis with nodulosis and arthritis with cardiac defects. Eur J Hum Genet (2008) 0.88
Juvenile hyaline fibromatosis and infantile systemic hyalinosis overlap associated with a novel mutation in capillary morphogenesis protein-2 gene. Am J Dermatopathol (2007) 0.87
Evaluation of H3 histone methylation and colony formation in erythroid progenitors treated with thalidomide and sodium butyrate. Lab Hematol (2013) 0.87
The Krüppel traffic report: cooperative signals direct KLF8 nuclear transport. Cell Res (2009) 0.86
Krüppel cripples prostate cancer: KLF6 progress and prospects. Am J Pathol (2003) 0.86
Ligand-dependent corepressor (LCoR) recruitment by Kruppel-like factor 6 (KLF6) regulates expression of the cyclin-dependent kinase inhibitor CDKN1A gene. J Biol Chem (2012) 0.86
KLF6 allelic loss is associated with tumor recurrence and markedly decreased survival in head and neck squamous cell carcinoma. Int J Cancer (2007) 0.86
Functional role of the KLF6 tumour suppressor gene in gastric cancer. Eur J Cancer (2008) 0.85
Shaking the family tree: identification of novel and biologically active alternatively spliced isoforms across the KLF family of transcription factors. FASEB J (2012) 0.84
The roles of miR-146a in the differentiation of Jurkat T-lymphoblasts. Hematology (2013) 0.83
KLF6 is one transcription factor involved in regulating acid ceramidase gene expression. Biochim Biophys Acta (2006) 0.83
Bone marrow neoplastic niche in leukemia. Hematology (2013) 0.83
Prognostic and predictive value of copy number alterations in invasive breast cancer as determined by multiplex ligation-dependent probe amplification. Cell Oncol (Dordr) (2014) 0.83
Systemic hyalinosis: a distinctive early childhood-onset disorder characterized by mutations in the anthrax toxin receptor 2 gene (ANTRX2). Pediatrics (2006) 0.83
Morbid obesity resulting from inactivation of the ciliary protein CEP19 in humans and mice. Am J Hum Genet (2013) 0.82
Drug Intervention Response Predictions with PARADIGM (DIRPP) identifies drug resistant cancer cell lines and pathway mechanisms of resistance. Pac Symp Biocomput (2014) 0.82
The bone marrow metastasis niche in retinoblastoma. Cell Oncol (Dordr) (2015) 0.82
A study of TRAIL receptors in squamous cell carcinoma of the head and neck. Arch Otolaryngol Head Neck Surg (2005) 0.82
Sex steroids have differential effects on growth and gene expression in primary human prostatic epithelial cell cultures derived from the peripheral versus transition zones. Carcinogenesis (2005) 0.82
Multicentric osteolysis with nodulosis and arthropathy (MONA) with cardiac malformation, mimicking polyarticular juvenile idiopathic arthritis: case report and literature review. Eur J Pediatr (2013) 0.81
Minimal residual disease in acute lymphoblastic leukemia: optimal methods and clinical relevance, pitfalls and recent approaches. Med Oncol (2014) 0.81
First successful use of eltrombopag before surgery in a child with MYH9-related thrombocytopenia. Pediatrics (2013) 0.81
Detection of Gene Amplification by Multiplex Ligation- Dependent Probe Amplification in Comparison with In Situ Hybridization and Immunohistochemistry. Asian Pac J Cancer Prev (2015) 0.81
Prooxidant-antioxidant balance and hs-CRP in patients with beta-thalassemia major. Clin Lab (2014) 0.80
Torg-Winchester syndrome: lack of efficacy of pamidronate therapy. Clin Dysmorphol (2007) 0.80
Application of RNA-Seq transcriptome analysis: CD151 is an Invasion/Migration target in all stages of epithelial ovarian cancer. J Ovarian Res (2012) 0.79
Biology and bioinformatics of myeloma cell. Lab Hematol (2012) 0.79
Loss of MMP-2 in murine osteoblasts upregulates osteopontin and bone sialoprotein expression in a circuit regulating bone homeostasis. Dis Model Mech (2012) 0.79
Expressional correlation of human epidermal growth factor receptor 2, estrogen/progesterone receptor and protein 53 in breast cancer. Asian Pac J Cancer Prev (2013) 0.79
G-CSF induces up-regulation of CXCR4 expression in human hematopoietic stem cells by beta-adrenergic agonist. Hematology (2014) 0.79
Comparison between gallbladder serosal and mucosal patch in duodenal injuries repair in dogs. J Invest Surg (2009) 0.78
The role of notch signaling in bone marrow niche. Hematology (2014) 0.78
Expression profiling of breast cancer patients treated with tamoxifen: prognostic or predictive significance. Med Oncol (2014) 0.77
IGFBP-4 tumor and serum levels are increased across all stages of epithelial ovarian cancer. J Ovarian Res (2012) 0.77
MYH9 spectrum of autosomal-dominant giant platelet syndromes: unexpected association with fibulin-1 variant-D inactivation. Am J Hematol (2003) 0.77
Meta-analysis diagnostic accuracy of SNP-based pathogenicity detection tools: a case of UTG1A1 gene mutations. Int J Mol Epidemiol Genet (2013) 0.77
Regression Modeling and Meta-Analysis of Diagnostic Accuracy of SNP-Based Pathogenicity Detection Tools for UGT1A1 Gene Mutation. Genet Res Int (2013) 0.77
New insights in cellular and molecular aspects of BM niche in chronic myelogenous leukemia. Tumour Biol (2014) 0.77
Emerging roles of Kruppel-like factor 6 and Kruppel-like factor 6 splice variant 1 in ovarian cancer progression and treatment. Mt Sinai J Med (2009) 0.77
Bladder exstrophy and Epstein type congenital macrothrombocytopenia: evidence for a common cause? Am J Med Genet A (2006) 0.76
The role of the nervous system in hematopoietic stem cell mobilization. Lab Hematol (2013) 0.76
Evaluation of humoral immune function in patients with chronic idiopathic thrombocytopenic purpura. Iran J Allergy Asthma Immunol (2013) 0.75
Sensitive High-Resolution Melting Analysis for Screening of KRAS and BRAF Mutations in Iranian Human Metastatic Colorectal Cancers Asian Pac J Cancer Prev (2016) 0.75
Association between gene polymorphisms and clinical features in idiopathic thrombocytopenic purpura patients. Blood Coagul Fibrinolysis (2017) 0.75
Mutation Analysis of KRAS and BRAF Genes in Metastatic Colorectal Cancer: a First Large Scale Study from Iran. Asian Pac J Cancer Prev (2016) 0.75
Chromogenic In Situ Hybridisation Test for Breast Cancer Patients with Equivocal IHC Results - a Study from Iran. Asian Pac J Cancer Prev (2015) 0.75
A new feature of the MYH9-related syndrome: chronic transaminase elevation. Hepatology (2012) 0.75
Pattern of immunoglobulin and T-cell receptor-δ/γ gene rearrangements in Iranian children with B-precursor acute lymphoblastic leukemia. Hematology (2014) 0.75
The role of Pax5 in leukemia: diagnosis and prognosis significance. Med Oncol (2014) 0.75
Regulatory effect of chemokines in bone marrow niche. Cell Tissue Res (2015) 0.75
Frequency of beta-thalassemia or beta-hemoglobinopathy carriers simultaneously affected with alpha-thalassemia in Iran. Clin Lab (2014) 0.75
The Influence of Polymorphisms in Disease Severity in β-Thalassemia. Biochem Genet (2015) 0.75
Molecular basis of chronic lymphocytic leukemia diagnosis and prognosis. Cell Oncol (Dordr) (2015) 0.75