Published in J Invest Dermatol on November 18, 2010
Genome-wide association analyses identify 13 new susceptibility loci for generalized vitiligo. Nat Genet (2012) 1.81
Six decades of vitiligo genetics: genome-wide studies provide insights into autoimmune pathogenesis. J Invest Dermatol (2011) 1.15
Modern vitiligo genetics sheds new light on an ancient disease. J Dermatol (2013) 1.12
Genome-wide analysis identifies a quantitative trait locus in the MHC class II region associated with generalized vitiligo age of onset. J Invest Dermatol (2011) 1.08
Next-generation DNA re-sequencing identifies common variants of TYR and HLA-A that modulate the risk of generalized vitiligo via antigen presentation. J Invest Dermatol (2012) 1.07
The genetics of generalized vitiligo: autoimmune pathways and an inverse relationship with malignant melanoma. Genome Med (2010) 1.07
Accounting for eXentricities: analysis of the X chromosome in GWAS reveals X-linked genes implicated in autoimmune diseases. PLoS One (2014) 1.04
Current aspects of vitiligo genetics. Postepy Dermatol Alergol (2014) 1.01
Vitiligo--part 1. An Bras Dermatol (2014) 0.96
Recent progress in the genetics of generalized vitiligo. J Genet Genomics (2011) 0.91
Nonsegmental vitiligo and autoimmune mechanism. Dermatol Res Pract (2011) 0.89
Concise review of recent studies in vitiligo. Qatar Med J (2013) 0.88
XWAS: A Software Toolset for Genetic Data Analysis and Association Studies of the X Chromosome. J Hered (2015) 0.87
Highlights in pathogenesis of vitiligo. World J Clin Cases (2015) 0.82
Systemic analyses of immunophenotypes of peripheral T cells in non-segmental vitiligo: implication of defective natural killer T cells. Pigment Cell Melanoma Res (2012) 0.82
Cellular stress and innate inflammation in organ-specific autoimmunity: lessons learned from vitiligo. Immunol Rev (2016) 0.80
Genetic Susceptibility to Vitiligo: GWAS Approaches for Identifying Vitiligo Susceptibility Genes and Loci. Front Genet (2016) 0.78
FOXP3 is a promising and potential candidate gene in generalised vitiligo susceptibility. Front Genet (2015) 0.77
Analysis of oxidative stress status, catalase and catechol-O-methyltransferase polymorphisms in Egyptian vitiligo patients. PLoS One (2014) 0.77
Recent Insights into the Role of Unfolded Protein Response in ER Stress in Health and Disease. Front Cell Dev Biol (2017) 0.77
Male gender bias in autism and pediatric autoimmunity. Autism Res (2012) 0.76
Dissecting the role of the FOXP3 gene in the joint genetic susceptibility to autoimmune thyroiditis and diabetes: a genetic and functional analysis. Gene (2014) 0.75
Vitiligo blood transcriptomics provides new insights into disease mechanisms and identifies potential novel therapeutic targets. BMC Genomics (2017) 0.75
Recent advances in understanding vitiligo. F1000Res (2016) 0.75
Autoimmune vitiligo in rheumatic disease in the mestizo Mexican population. Biomed Rep (2016) 0.75
PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet (2007) 209.92
Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics (2004) 125.23
Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits. Bioinformatics (2003) 17.92
A comprehensive review of genetic association studies. Genet Med (2002) 16.75
Assessing the impact of population stratification on genetic association studies. Nat Genet (2004) 16.28
A unified stepwise regression procedure for evaluating the relative effects of polymorphisms within a gene using case/control or family data: application to HLA in type 1 diabetes. Am J Hum Genet (2001) 8.47
Epidemiology of vitiligo and associated autoimmune diseases in Caucasian probands and their families. Pigment Cell Res (2003) 3.07
Variant of TYR and autoimmunity susceptibility loci in generalized vitiligo. N Engl J Med (2010) 2.47
Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC. Nat Genet (2010) 1.69
Early disease onset and increased risk of other autoimmune diseases in familial generalized vitiligo. Pigment Cell Res (2005) 1.50
Testing association for markers on the X chromosome. Genet Epidemiol (2007) 1.43
Common variants in FOXP1 are associated with generalized vitiligo. Nat Genet (2010) 1.25
Interleukin-1 gene cluster polymorphisms in sarcoidosis and idiopathic pulmonary fibrosis. Am J Respir Crit Care Med (2002) 1.22
Novel vitiligo susceptibility loci on chromosomes 7 (AIS2) and 8 (AIS3), confirmation of SLEV1 on chromosome 17, and their roles in an autoimmune diathesis. Am J Hum Genet (2004) 1.15
Mapping of an autoimmunity susceptibility locus (AIS1) to chromosome 1p31.3-p32.2. Hum Mol Genet (2002) 1.09
Candidate functional promoter variant in the FOXD3 melanoblast developmental regulator gene in autosomal dominant vitiligo. J Invest Dermatol (2005) 1.08
Genetic variation of promoter sequence modulates XBP1 expression and genetic risk for vitiligo. PLoS Genet (2009) 1.07
STAT4 polymorphism in a Chinese Han population with Vogt-Koyanagi-Harada syndrome and Behçet's disease. Hum Immunol (2010) 1.06
Genetic association of the catalase gene (CAT) with vitiligo susceptibility. Pigment Cell Res (2002) 1.03
CTLA4 polymorphisms are associated with vitiligo, in patients with concomitant autoimmune diseases. Pigment Cell Res (2005) 1.02
'VIT1', a novel gene associated with vitiligo. Pigment Cell Res (2001) 1.01
A novel linkage to generalized vitiligo on 4q13-q21 identified in a genomewide linkage analysis of Chinese families. Am J Hum Genet (2005) 1.00
PTPN22 is genetically associated with risk of generalized vitiligo, but CTLA4 is not. J Invest Dermatol (2008) 1.00
The autoimmune regulator gene (AIRE) is strongly associated with vitiligo. Br J Dermatol (2008) 0.99
A genomewide screen for generalized vitiligo: confirmation of AIS1 on chromosome 1p31 and evidence for additional susceptibility loci. Am J Hum Genet (2003) 0.99
Analysis of a microsatellite polymorphism of the cytotoxic T-lymphocyte antigen-4 gene in patients with vitiligo. Br J Dermatol (1999) 0.93
Genes of the LMP/TAP cluster are associated with the human autoimmune disease vitiligo. Genes Immun (2003) 0.92
The susceptibility to vitiligo is associated with NF-E2-related factor2 (Nrf2) gene polymorphisms: a study on Chinese Han population. Exp Dermatol (2008) 0.90
Association of interferon-gamma and tumor necrosis factor alpha polymorphisms with susceptibility to vitiligo in Iranian patients. Arch Dermatol Res (2008) 0.90
Possible association of the CD4 gene polymorphism with vitiligo in an Iranian population. Clin Exp Dermatol (2009) 0.89
Compound heterozygosity for two MSH6 mutations in a patient with early onset colorectal cancer, vitiligo and systemic lupus erythematosus. Am J Med Genet A (2008) 0.88
Evidence for two susceptibility loci on chromosomes 22q12 and 6p21-p22 in Chinese generalized vitiligo families. J Invest Dermatol (2007) 0.87
Association of catalase T/C exon 9 and glutathione peroxidase codon 200 polymorphisms in relation to their activities and oxidative stress with vitiligo susceptibility in Gujarat population. Pigment Cell Res (2007) 0.87
Immuno-modulatory gene polymorphisms and outcome in breast and ovarian cancer. Immunol Invest (2009) 0.86
Genetic variants of the DDR1 gene are associated with vitiligo in two independent Brazilian population samples. J Invest Dermatol (2010) 0.85
CTLA4 and generalized vitiligo: two genetic association studies and a meta-analysis of published data. Pigment Cell Melanoma Res (2009) 0.84
Might there be a link between mannose binding lectin and vitiligo? Eur J Dermatol (2007) 0.84
Autoimmune diseases and vitamin D receptor Apa-I polymorphism are associated with vitiligo in a small inbred Romanian community. Acta Derm Venereol (2006) 0.84
Association between IL4 (-590), ACE (I)/(D), CCR5 (Delta32), CTLA4 (+49) and IL1-RN (VNTR in intron 2) gene polymorphisms and vitiligo. Eur J Dermatol (2009) 0.84
Analysis of allelic variants in the catalase gene in patients with the skin depigmenting disorder vitiligo. Biochem Biophys Res Commun (2006) 0.84
Lack of association with TNF-alpha-308 promoter polymorphism in patients with vitiligo. Arch Dermatol Res (2006) 0.83
Platelet-derived growth factor receptor alpha gene mutations in vitiligo vulgaris. Acta Derm Venereol (2010) 0.83
Association of Interleukin-10 gene promoter polymorphisms in Saudi patients with vitiligo. Dis Markers (2008) 0.83
The ACE gene I/ D polymorphism is not associated with generalized vitiligo susceptibility in Gujarat population. Pigment Cell Melanoma Res (2008) 0.83
Promoter variant in the catalase gene is associated with vitiligo in Chinese people. J Invest Dermatol (2010) 0.83
Association of glutathione S-transferase gene polymorphisms (GSTM1 and GSTT1) of vitiligo in Korean population. Life Sci (2007) 0.82
Association of TXNDC5 gene polymorphisms and susceptibility to nonsegmental vitiligo in the Korean population. Br J Dermatol (2009) 0.82
Identification of a type 1 diabetes-associated CD4 promoter haplotype with high constitutive activity. Scand J Immunol (2004) 0.82
The association between endothelin-1 gene polymorphisms and susceptibility to vitiligo in a Korean population. Exp Dermatol (2007) 0.82
Homogeneous assay of rs4343, an ACE I/D proxy, and an analysis in the British Women's Heart and Health Study (BWHHS). Dis Markers (2008) 0.81
Association of angiotensin converting enzyme gene I/D polymorphism of vitiligo in Korean population. Pigment Cell Res (2004) 0.81
Functional polymorphisms of the FAS gene associated with risk of vitiligo in Chinese populations: a case-control analysis. J Invest Dermatol (2008) 0.81
Association study between catalase gene polymorphisms and the susceptibility to vitiligo in Korean population. Exp Dermatol (2006) 0.81
Association of COX2 functional polymorphisms and the risk of vitiligo in Chinese populations. J Dermatol Sci (2008) 0.80
Exon-3 polymorphism of CTLA-4 gene in Turkish patients with vitiligo. J Dermatol Sci (2005) 0.80
Promoter polymorphism -119C/G in MYG1 (C12orf10) gene is related to vitiligo susceptibility and Arg4Gln affects mitochondrial entrance of Myg1. BMC Med Genet (2010) 0.80
Lack of genetic association of promoter and structural variants of mannan-binding lectin (MBL2) gene with susceptibility to generalized vitiligo. Br J Dermatol (2009) 0.79
A functional single-nucleotide polymorphism in the catechol-O-methyltransferase gene alter vitiligo risk in a Chinese population. Arch Dermatol Res (2008) 0.79
CTLA-4 A49G gene polymorphism is not associated with vitiligo in South Indian population. Indian J Dermatol (2010) 0.79
Association of UVRAG polymorphisms with susceptibility to non-segmental vitiligo in a Korean sample. Exp Dermatol (2010) 0.79
Association study between keratinocyte-derived growth factor gene polymorphisms and susceptibility to vitiligo vulgaris in a Taiwanese population: potential involvement of stem cell factor. Br J Dermatol (2009) 0.79
Vitiligo-associated multiple autoimmune disease is not associated with genetic variation in AIRE. Pigment Cell Res (2007) 0.78
An insertion/deletion polymorphism in the gene encoding angiotensin converting enzyme is not associated with generalised vitiligo in an English population. Arch Dermatol Res (2005) 0.77
Association of thymic stromal lymphopoietin gene -847C>T polymorphism in generalized vitiligo. Exp Dermatol (2009) 0.77
Association of estrogen receptor 1 intron 1 C/T polymorphism in Korean vitiligo patients. J Dermatol Sci (2004) 0.77
Genetic polymorphisms of glutathione S-transferase and risk of vitiligo in the Chinese population. J Invest Dermatol (2009) 0.77
Association between polymorphisms of discoidin domain receptor tyrosine kinase 1 (DDR1) and non-segmental vitiligo in the Korean population. Eur J Dermatol (2009) 0.77
Transforming growth factor beta receptor II (TGFBR2) polymorphisms and the association with nonsegmental vitiligo in the Korean population. Int J Immunogenet (2010) 0.77
Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med (2011) 45.46
Dabrafenib in BRAF-mutated metastatic melanoma: a multicentre, open-label, phase 3 randomised controlled trial. Lancet (2012) 13.89
Propranolol for severe hemangiomas of infancy. N Engl J Med (2008) 11.32
Effect of iodine intake on thyroid diseases in China. N Engl J Med (2006) 5.46
Combined BRAF and MEK inhibition versus BRAF inhibition alone in melanoma. N Engl J Med (2014) 4.71
NALP1 in vitiligo-associated multiple autoimmune disease. N Engl J Med (2007) 3.99
Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage. Nat Biotechnol (2011) 3.97
Epidemiology of vitiligo and associated autoimmune diseases in Caucasian probands and their families. Pigment Cell Res (2003) 3.07
Revised nomenclature and classification of inherited ichthyoses: results of the First Ichthyosis Consensus Conference in Sorèze 2009. J Am Acad Dermatol (2010) 2.87
Rab38 and Rab32 control post-Golgi trafficking of melanogenic enzymes. J Cell Biol (2006) 2.79
Hermansky-Pudlak syndrome type 7 (HPS-7) results from mutant dysbindin, a member of the biogenesis of lysosome-related organelles complex 1 (BLOC-1). Nat Genet (2003) 2.78
Propranolol for severe infantile hemangiomas: follow-up report. Pediatrics (2009) 2.76
Clinical practice. Vitiligo. N Engl J Med (2009) 2.72
Antioxidant supplementation increases the risk of skin cancers in women but not in men. J Nutr (2007) 2.66
Functions of adaptor protein (AP)-3 and AP-1 in tyrosinase sorting from endosomes to melanosomes. Mol Biol Cell (2005) 2.56
Variant of TYR and autoimmunity susceptibility loci in generalized vitiligo. N Engl J Med (2010) 2.47
Natural history of dilated cardiomyopathy due to lamin A/C gene mutations. J Am Coll Cardiol (2003) 2.47
Pax6 is a human neuroectoderm cell fate determinant. Cell Stem Cell (2010) 2.46
The melanocortin-1 receptor gene mediates female-specific mechanisms of analgesia in mice and humans. Proc Natl Acad Sci U S A (2003) 2.29
The A118G single nucleotide polymorphism of the mu-opioid receptor gene (OPRM1) is associated with pressure pain sensitivity in humans. J Pain (2005) 2.23
New developments in our understanding of acne pathogenesis and treatment. Exp Dermatol (2009) 2.16
Cell-specific ATP7A transport sustains copper-dependent tyrosinase activity in melanosomes. Nature (2008) 2.15
Familial aggregation of common sequence variants on 15q24-25.1 in lung cancer. J Natl Cancer Inst (2008) 2.15
Seroprevalence and risk factors of chikungunya virus infection in Mayotte, Indian Ocean, 2005-2006: a population-based survey. PLoS One (2008) 2.14
BLOC-1 is required for cargo-specific sorting from vacuolar early endosomes toward lysosome-related organelles. Mol Biol Cell (2006) 2.11
p16(Ink4a) in melanocyte senescence and differentiation. J Natl Cancer Inst (2002) 2.09
Tau accumulation activates the unfolded protein response by impairing endoplasmic reticulum-associated degradation. J Neurosci (2013) 2.04
Chemical and instrumental approaches to treat hyperpigmentation. Pigment Cell Res (2003) 2.04
Is the loose anagen hair syndrome a keratin disorder? A clinical and molecular study. Arch Dermatol (2002) 2.03
WWP2 promotes degradation of transcription factor OCT4 in human embryonic stem cells. Cell Res (2009) 1.97
Hyperkeratotic head and neck Malassezia dermatosis. Dermatology (2006) 1.93
EGFR-T790M is a rare lung cancer susceptibility allele with enhanced kinase activity. Cancer Res (2007) 1.91
Extreme genetic risk for type 1A diabetes. Proc Natl Acad Sci U S A (2006) 1.90
Hypopigmenting agents: an updated review on biological, chemical and clinical aspects. Pigment Cell Res (2006) 1.89
Post-epidemic Chikungunya disease on Reunion Island: course of rheumatic manifestations and associated factors over a 15-month period. PLoS Negl Trop Dis (2009) 1.87
Analysis of single nucleotide polymorphisms identifies major type 1A diabetes locus telomeric of the major histocompatibility complex. Diabetes (2007) 1.84
Platelet microRNA-mRNA coexpression profiles correlate with platelet reactivity. Blood (2011) 1.83
Fine mapping of chromosome 6q23-25 region in familial lung cancer families reveals RGS17 as a likely candidate gene. Clin Cancer Res (2009) 1.83
Genome-wide association analyses identify 13 new susceptibility loci for generalized vitiligo. Nat Genet (2012) 1.81
Integrative analysis of epigenetic modulation in melanoma cell response to decitabine: clinical implications. PLoS One (2009) 1.80
Deletion of the SLUG (SNAI2) gene results in human piebaldism. Am J Med Genet A (2003) 1.72
Efficacy and safety of tacrolimus ointment compared with that of hydrocortisone acetate ointment in children with atopic dermatitis. J Allergy Clin Immunol (2002) 1.71
Presence of de novo mutations in autosomal dominant polycystic kidney disease patients without family history. Am J Kidney Dis (2008) 1.71
Impact of body mass index and obesity on clinical response to systemic treatment for psoriasis. Evidence from the Psocare project. Dermatology (2008) 1.70
Human squamous cell carcinomas evade the immune response by down-regulation of vascular E-selectin and recruitment of regulatory T cells. J Exp Med (2008) 1.67
Alpha-myosin heavy chain: a sarcomeric gene associated with dilated and hypertrophic phenotypes of cardiomyopathy. Circulation (2005) 1.67
Hermansky-Pudlak syndrome is caused by mutations in HPS4, the human homolog of the mouse light-ear gene. Nat Genet (2002) 1.67
Mutant HSP70 reverses autoimmune depigmentation in vitiligo. Sci Transl Med (2013) 1.66
Effect of the secretory small GTPase Rab27B on breast cancer growth, invasion, and metastasis. J Natl Cancer Inst (2010) 1.65
ARF functions as a melanoma tumor suppressor by inducing p53-independent senescence. Proc Natl Acad Sci U S A (2007) 1.61
Clinical and translational scientist career success: metrics for evaluation. Clin Transl Sci (2012) 1.61
Forward genetic screen for malignant peripheral nerve sheath tumor formation identifies new genes and pathways driving tumorigenesis. Nat Genet (2013) 1.60
SACRAL syndrome: spinal dysraphism, anogenital, cutaneous, renal and urologic anomalies, associated with an angioma of lumbosacral localization. Dermatology (2007) 1.60
Expansion of the human mu-opioid receptor gene architecture: novel functional variants. Hum Mol Genet (2008) 1.59
Interventions for vitiligo. Cochrane Database Syst Rev (2015) 1.57
The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules. J Neurosci (2010) 1.57
The definition and assessment of vitiligo: a consensus report of the Vitiligo European Task Force. Pigment Cell Res (2007) 1.57
A flagellar polycystin-2 homolog required for male fertility in Drosophila. Curr Biol (2003) 1.56
Activating autoantibodies against the calcium-sensing receptor detected in two patients with autoimmune polyendocrine syndrome type 1. J Clin Endocrinol Metab (2009) 1.55
Skin colonization by Malassezia species in neonates: a prospective study and relationship with neonatal cephalic pustulosis. Arch Dermatol (2002) 1.55
Patient perspectives on the management of atopic dermatitis. J Allergy Clin Immunol (2006) 1.55
Pluripotency can be rapidly and efficiently induced in human amniotic fluid-derived cells. Hum Mol Genet (2009) 1.54
Ru2 and Ru encode mouse orthologs of the genes mutated in human Hermansky-Pudlak syndrome types 5 and 6. Nat Genet (2003) 1.54
Allelic variation in TAS2R bitter receptor genes associates with variation in sensations from and ingestive behaviors toward common bitter beverages in adults. Chem Senses (2010) 1.53