The relationship between methylation of the Syk gene in the promoter region and the genesis of lung cancer.

PubWeight™: 0.89‹?›

🔗 View Article (PMID 21086786)

Published in Clin Lab on January 01, 2010

Authors

Li Ma1, Shangwen Dong, Peng Zhang, Ning Xu, Huiqin Yan, Hongyu Liu, Yongwen Li, Qinghua Zhou

Author Affiliations

1: Medical Department of Medical Oncology, Tianjin Medical University General Hospital, Anshan Road No. 154, Heping District, Tianjin 300052, China.

Articles by these authors

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet (2013) 8.02

TGM6 identified as a novel causative gene of spinocerebellar ataxias using exome sequencing. Brain (2010) 3.66

Immunohistochemical localization of programmed death-1 ligand-1 (PD-L1) in gastric carcinoma and its clinical significance. Acta Histochem (2006) 3.24

Intracellular MHC class II molecules promote TLR-triggered innate immune responses by maintaining activation of the kinase Btk. Nat Immunol (2011) 3.12

Therapeutic target database update 2012: a resource for facilitating target-oriented drug discovery. Nucleic Acids Res (2011) 3.05

Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54. Nat Genet (2010) 2.95

Identification of PRRT2 as the causative gene of paroxysmal kinesigenic dyskinesias. Brain (2011) 2.80

Pathway analysis of coronary atherosclerosis. Physiol Genomics (2005) 2.59

Transforming growth factor-beta-regulated miR-24 promotes skeletal muscle differentiation. Nucleic Acids Res (2008) 2.44

Association analyses identify six new psoriasis susceptibility loci in the Chinese population. Nat Genet (2010) 2.41

Influence of chemotherapy on EGFR mutation status among patients with non-small-cell lung cancer. J Clin Oncol (2012) 2.31

Suppression of RNA interference by adenovirus virus-associated RNA. J Virol (2005) 2.29

In vitro derivation of functional insulin-producing cells from human embryonic stem cells. Cell Res (2007) 2.28

Molecular characterization of geminivirus-derived small RNAs in different plant species. Nucleic Acids Res (2006) 2.26

Association between vitamin D and risk of colorectal cancer: a systematic review of prospective studies. J Clin Oncol (2011) 2.24

Expression of mutant p53 proteins implicates a lineage relationship between neural stem cells and malignant astrocytic glioma in a murine model. Cancer Cell (2009) 2.14

No significant association between the TP53 codon 72 polymorphism and breast cancer risk: a meta-analysis of 21 studies involving 24,063 subjects. Breast Cancer Res Treat (2010) 2.12

MRI-based finite-element analysis of left ventricular aneurysm. Am J Physiol Heart Circ Physiol (2005) 2.06

Helical myofiber orientation after myocardial infarction and left ventricular surgical restoration in sheep. J Thorac Cardiovasc Surg (2005) 2.06

Obesity and risk of colorectal cancer: a systematic review of prospective studies. PLoS One (2013) 2.02

Exome sequencing reveals mutations in TRPV3 as a cause of Olmsted syndrome. Am J Hum Genet (2012) 1.91

Aspirin for primary prevention of cardiovascular events in patients with diabetes: A meta-analysis. Diabetes Res Clin Pract (2009) 1.90

MicroRNA-99a inhibits hepatocellular carcinoma growth and correlates with prognosis of patients with hepatocellular carcinoma. J Biol Chem (2011) 1.88

Identification of bacteria and bacteria-associated chemical cues that mediate oviposition site preferences by Aedes aegypti. Proc Natl Acad Sci U S A (2008) 1.88

SP1 mediates the link between methylation of the tumour suppressor miR-149 and outcome in colorectal cancer. J Pathol (2013) 1.87

Tumor-associated microglia/macrophages enhance the invasion of glioma stem-like cells via TGF-β1 signaling pathway. J Immunol (2012) 1.86

The status of glycemic control: A cross-sectional study of outpatients with type 2 diabetes mellitus across primary, secondary, and tertiary hospitals in the Jiangsu province of China. Clin Ther (2010) 1.83

Sequence composition, organization, and evolution of the core Triticeae genome. Plant J (2004) 1.79

Homoeologous recombination, chromosome engineering and crop improvement. Chromosome Res (2007) 1.73

Expansion of regulatory T cells via IL-2/anti-IL-2 mAb complexes suppresses experimental myasthenia. Eur J Immunol (2010) 1.72

Space-time crystals of trapped ions. Phys Rev Lett (2012) 1.71

Central nervous system (CNS)-resident natural killer cells suppress Th17 responses and CNS autoimmune pathology. J Exp Med (2010) 1.70

Role of the CaMKII/NMDA receptor complex in the maintenance of synaptic strength. J Neurosci (2011) 1.70

Interleukin-2/interleukin-2 antibody therapy induces target organ natural killer cells that inhibit central nervous system inflammation. Ann Neurol (2011) 1.67

A sodalite-like framework based on octacyanomolybdate and neodymium with guest methanol molecules and neodymium octahydrate ions. Angew Chem Int Ed Engl (2006) 1.67

miR-150 as a potential biomarker associated with prognosis and therapeutic outcome in colorectal cancer. Gut (2011) 1.66

Four-color DNA sequencing with 3'-O-modified nucleotide reversible terminators and chemically cleavable fluorescent dideoxynucleotides. Proc Natl Acad Sci U S A (2008) 1.64

MicroRNA patterns associated with clinical prognostic parameters and CNS relapse prediction in pediatric acute leukemia. PLoS One (2009) 1.62

Targeted disruption of Smad4 in cardiomyocytes results in cardiac hypertrophy and heart failure. Circ Res (2005) 1.62

Clinical significance of EML4-ALK fusion gene and association with EGFR and KRAS gene mutations in 208 Chinese patients with non-small cell lung cancer. PLoS One (2013) 1.57

Shear stress regulation of Krüppel-like factor 2 expression is flow pattern-specific. Biochem Biophys Res Commun (2006) 1.57

The return periods and risk assessment of severe dust storms in Inner Mongolia with consideration of the main contributing factors. Environ Monit Assess (2011) 1.56

Predictive factors of type 2 diabetes mellitus remission following bariatric surgery: a meta-analysis. Obes Surg (2015) 1.55

Exome sequencing and unrelated findings in the context of complex disease research: ethical and clinical implications. Discov Med (2011) 1.52

Kielin/chordin-like protein attenuates both acute and chronic renal injury. J Am Soc Nephrol (2013) 1.51

Kupffer cells mediate leptin-induced liver fibrosis. Gastroenterology (2009) 1.48

MiR-26a enhances metastasis potential of lung cancer cells via AKT pathway by targeting PTEN. Biochim Biophys Acta (2012) 1.48

Does normothermic normokalemic simultaneous antegrade/retrograde perfusion improve myocardial oxygenation and energy metabolism for hypertrophied hearts? Ann Thorac Surg (2007) 1.48

Mass screening for prostate cancer: a comparative study in Natori, Japan and Changchun, China. Urology (2003) 1.47

Candidate microRNA biomarkers in human colorectal cancer: systematic review profiling studies and experimental validation. Int J Cancer (2011) 1.46

Development and application of transgenic technologies in cassava. Plant Mol Biol (2004) 1.46

High nuclear grade, frequent mitotic activity, cyclin D1 and p53 overexpression are associated with stromal invasion in mammary intracystic papillary carcinoma. Breast J (2005) 1.44

Extremely low genetic diversity indicating the endangered status of Ranodon sibiricus (Amphibia: Caudata) and implications for phylogeography. PLoS One (2012) 1.44

Transcriptome profiling of low temperature-treated cassava apical shoots showed dynamic responses of tropical plant to cold stress. BMC Genomics (2012) 1.43

Lack of association between HER2 codon 655 polymorphism and breast cancer susceptibility: meta-analysis of 22 studies involving 19,341 subjects. Breast Cancer Res Treat (2010) 1.43

Diethyl 3,3'-(phenyl-methyl-ene)bis-(1H-indole-2-carboxyl-ate). Acta Crystallogr Sect E Struct Rep Online (2012) 1.42

SIRT1 promotes N-Myc oncogenesis through a positive feedback loop involving the effects of MKP3 and ERK on N-Myc protein stability. PLoS Genet (2011) 1.41

The proteomics of lipid droplets: structure, dynamics, and functions of the organelle conserved from bacteria to humans. J Lipid Res (2012) 1.40

The BioCassava plus program: biofortification of cassava for sub-Saharan Africa. Annu Rev Plant Biol (2011) 1.40

An improved elastase-based method to create a saccular aneurysm rabbit model. Br J Neurosurg (2013) 1.40

The role of mechanical bowel preparation before ileal urinary diversion: a systematic review and meta-analysis. Urol Int (2014) 1.39

Prospective study of chemotherapy in combination with cytokine-induced killer cells in patients suffering from advanced non-small cell lung cancer. Anticancer Res (2009) 1.38

[Results of randomized, multicenter, double-blind phase III trial of rh-endostatin (YH-16) in treatment of advanced non-small cell lung cancer patients]. Zhongguo Fei Ai Za Zhi (2005) 1.38

Robot-assisted versus conventional laparoscopic surgery for colorectal disease, focusing on rectal cancer: a meta-analysis. Ann Surg Oncol (2012) 1.35

MiR-155 is overexpressed in patients with atopic dermatitis and modulates T-cell proliferative responses by targeting cytotoxic T lymphocyte-associated antigen 4. J Allergy Clin Immunol (2010) 1.32

Glycomic analyses of mouse models of congenital muscular dystrophy. J Biol Chem (2011) 1.32

Therapeutic target database update 2014: a resource for targeted therapeutics. Nucleic Acids Res (2013) 1.31

Multiple genome alignments facilitate development of NPCL markers: a case study of tetrapod phylogeny focusing on the position of turtles. Mol Biol Evol (2011) 1.30

Effect of ventricular size and patch stiffness in surgical anterior ventricular restoration: a finite element model study. Ann Thorac Surg (2005) 1.30

The glycolytic inhibitor 2-deoxyglucose activates multiple prosurvival pathways through IGF1R. J Biol Chem (2009) 1.30

Aberrant activation of the androgen receptor by NF-kappaB2/p52 in prostate cancer cells. Cancer Res (2010) 1.29

Genotypic variants at 2q33 and risk of esophageal squamous cell carcinoma in China: a meta-analysis of genome-wide association studies. Hum Mol Genet (2012) 1.28

Identification of human intestinal alkaline sphingomyelinase as a novel ecto-enzyme related to the nucleotide phosphodiesterase family. J Biol Chem (2003) 1.28

miR-223 regulates migration and invasion by targeting Artemin in human esophageal carcinoma. J Biomed Sci (2011) 1.27

An LRRTM4-HSPG complex mediates excitatory synapse development on dentate gyrus granule cells. Neuron (2013) 1.26

Distribution and progression of chondrocyte damage in a whole-organ model of human ankle intra-articular fracture. J Bone Joint Surg Am (2011) 1.26

Molecular basis of the interaction of Saccharomyces cerevisiae Eaf3 chromo domain with methylated H3K36. J Biol Chem (2008) 1.26

Acetylated STAT3 is crucial for methylation of tumor-suppressor gene promoters and inhibition by resveratrol results in demethylation. Proc Natl Acad Sci U S A (2012) 1.26

Treatment of advanced gastric cancer by chemotherapy combined with autologous cytokine-induced killer cells. Anticancer Res (2006) 1.25

Black silicon with self-cleaning surface prepared by wetting processes. Nanoscale Res Lett (2013) 1.25

IL28B genetic variation is associated with spontaneous clearance of hepatitis C virus, treatment response, serum IL-28B levels in Chinese population. PLoS One (2012) 1.25

CD4 +CD25 + regulatory T cells decreased the antitumor activity of cytokine-induced killer (CIK) cells of lung cancer patients. J Clin Immunol (2007) 1.24

Role of positive selection in the retention of duplicate genes in mammalian genomes. Proc Natl Acad Sci U S A (2006) 1.24

Genome-wide association of bipolar disorder suggests an enrichment of replicable associations in regions near genes. PLoS Genet (2011) 1.23

Confirmation by exome sequencing of the pathogenic role of NCSTN mutations in acne inversa (hidradenitis suppurativa). J Invest Dermatol (2011) 1.23

Influence of liver cancer on lipid and lipoprotein metabolism. Lipids Health Dis (2006) 1.23

Magnetic resonance imaging-based finite element stress analysis after linear repair of left ventricular aneurysm. J Thorac Cardiovasc Surg (2008) 1.22

Molecular mechanisms underlying the analgesic property of intrathecal dexmedetomidine and its neurotoxicity evaluation: an in vivo and in vitro experimental study. PLoS One (2013) 1.21

Elevated oncofoetal miR-17-5p expression regulates colorectal cancer progression by repressing its target gene P130. Nat Commun (2012) 1.21

Role of hepatitis B virus genotype mixture, subgenotypes C2 and B2 on hepatocellular carcinoma: compared with chronic hepatitis B and asymptomatic carrier state in the same area. Carcinogenesis (2008) 1.20

Proteomics identification of desmin as a potential oncofetal diagnostic and prognostic biomarker in colorectal cancer. Mol Cell Proteomics (2009) 1.20

Cohort Profile: the Dongfeng-Tongji cohort study of retired workers. Int J Epidemiol (2012) 1.19

Signature of circulating microRNAs as potential biomarkers in vulnerable coronary artery disease. PLoS One (2013) 1.19

Weak anti-localization and quantum oscillations of surface states in topological insulator Bi₂Se₂Te. Sci Rep (2012) 1.19

Intranasal administration with NAD+ profoundly decreases brain injury in a rat model of transient focal ischemia. Front Biosci (2007) 1.18

Cdc7-Dbf4 kinase overexpression in multiple cancers and tumor cell lines is correlated with p53 inactivation. Neoplasia (2008) 1.18

Dimethyl 3,3'-(phenyl-methyl-ene)bis-(1H-indole-2-carboxyl-ate). Acta Crystallogr Sect E Struct Rep Online (2013) 1.18

Constitutive MHC class I molecules negatively regulate TLR-triggered inflammatory responses via the Fps-SHP-2 pathway. Nat Immunol (2012) 1.18