Paul Pharoah

Author PubWeight™ 113.09‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3. Nat Genet 2008 6.26
2 Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies. J Natl Cancer Inst 2010 4.54
3 Helicobacter pylori and interleukin 1 genotyping: an opportunity to identify high-risk individuals for gastric carcinoma. J Natl Cancer Inst 2002 4.43
4 Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33. Nat Genet 2010 4.20
5 Founder and recurrent CDH1 mutations in families with hereditary diffuse gastric cancer. JAMA 2007 3.62
6 Acceptability and accuracy of a non-endoscopic screening test for Barrett's oesophagus in primary care: cohort study. BMJ 2010 3.44
7 Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet 2010 3.37
8 Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk. Nat Genet 2012 3.19
9 Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study. Nat Genet 2011 3.07
10 Cell type-specific DNA methylation patterns in the human breast. Proc Natl Acad Sci U S A 2008 2.99
11 Sipa1 is a candidate for underlying the metastasis efficiency modifier locus Mtes1. Nat Genet 2005 2.92
12 Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer. PLoS Genet 2011 2.47
13 A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11. Hum Mol Genet 2012 2.45
14 A proinflammatory genetic profile increases the risk for chronic atrophic gastritis and gastric carcinoma. Gastroenterology 2003 2.39
15 Pathology of ovarian cancers in BRCA1 and BRCA2 carriers. Clin Cancer Res 2004 2.17
16 Relative and absolute risk of colorectal cancer for individuals with a family history: a meta-analysis. Eur J Cancer 2005 2.16
17 Predictive markers of anthracycline benefit: a prospectively planned analysis of the UK National Epirubicin Adjuvant Trial (NEAT/BR9601). Lancet Oncol 2010 2.01
18 Risk factors for breast cancer: a reanalysis of two case-control studies from 1926 and 1931. Epidemiology 2010 1.98
19 Incorporating genomics into breast and prostate cancer screening: assessing the implications. Genet Med 2013 1.91
20 Public health implications from COGS and potential for risk stratification and screening. Nat Genet 2013 1.79
21 Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression. Hum Mol Genet 2013 1.78
22 Genetic variation in the HSD17B1 gene and risk of prostate cancer. PLoS Genet 2005 1.67
23 Common breast cancer susceptibility loci are associated with triple-negative breast cancer. Cancer Res 2011 1.65
24 Model of the early development of diffuse gastric cancer in E-cadherin mutation carriers and its implications for patient screening. J Pathol 2004 1.59
25 Associations of common variants at 1p11.2 and 14q24.1 (RAD51L1) with breast cancer risk and heterogeneity by tumor subtype: findings from the Breast Cancer Association Consortium. Hum Mol Genet 2011 1.56
26 Cumulative impact of common genetic variants and other risk factors on colorectal cancer risk in 42,103 individuals. Gut 2012 1.52
27 Prediction of pathogenic mutations in patients with early-onset breast cancer by family history. Lancet 2003 1.52
28 Common germline genetic variation in antioxidant defense genes and survival after diagnosis of breast cancer. J Clin Oncol 2007 1.51
29 Endometrial cancer and genetic variation in PTEN, PIK3CA, AKT1, MLH1, and MSH2 within a population-based case-control study. Gynecol Oncol 2010 1.47
30 Verbal autopsy: reliability and validity estimates for causes of death in the Golestan Cohort Study in Iran. PLoS One 2010 1.47
31 Five glutathione s-transferase gene variants in 23,452 cases of lung cancer and 30,397 controls: meta-analysis of 130 studies. PLoS Med 2006 1.35
32 Role of genetic polymorphisms and ovarian cancer susceptibility. Mol Oncol 2009 1.33
33 CHEK2*1100delC heterozygosity in women with breast cancer associated with early death, breast cancer-specific death, and increased risk of a second breast cancer. J Clin Oncol 2012 1.29
34 BRCA1, BRCA2 and TP53 mutations in very early-onset breast cancer with associated risks to relatives. Eur J Cancer 2006 1.24
35 TGFβ induces the formation of tumour-initiating cells in claudinlow breast cancer. Nat Commun 2012 1.23
36 Identification and validation of prognostic markers in breast cancer with the complementary use of array-CGH and tissue microarrays. J Pathol 2005 1.19
37 Diabetes mellitus and its correlates in an Iranian adult population. PLoS One 2011 1.19
38 Molecular pathology in epidemiologic studies: a primer on key considerations. Cancer Epidemiol Biomarkers Prev 2010 1.14
39 Biological and prognostic associations of miR-205 and let-7b in breast cancer revealed by in situ hybridization analysis of micro-RNA expression in arrays of archival tumour tissue. J Pathol 2012 1.12
40 Refinement of the associations between risk of colorectal cancer and polymorphisms on chromosomes 1q41 and 12q13.13. Hum Mol Genet 2011 1.07
41 Shorter telomere length is associated with increased ovarian cancer risk in both familial and sporadic cases. J Med Genet 2012 1.04
42 A genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and supports a common genetic spectrum for breast cancer at any age. Cancer Epidemiol Biomarkers Prev 2014 1.03
43 Combined and interactive effects of environmental and GWAS-identified risk factors in ovarian cancer. Cancer Epidemiol Biomarkers Prev 2013 1.02
44 Role of CHEK2*1100delC in unselected series of non-BRCA1/2 male breast cancers. Int J Cancer 2004 1.01
45 Haplotypes of the estrogen receptor beta gene and breast cancer risk. Int J Cancer 2008 0.99
46 Genetic variation in SIPA1 in relation to breast cancer risk and survival after breast cancer diagnosis. Int J Cancer 2009 0.98
47 PSA-detected prostate cancer and the potential for dedifferentiation--estimating the proportion capable of progression. Int J Cancer 2011 0.98
48 9q31.2-rs865686 as a susceptibility locus for estrogen receptor-positive breast cancer: evidence from the Breast Cancer Association Consortium. Cancer Epidemiol Biomarkers Prev 2012 0.95
49 Translating genomics into improved population screening: hype or hope? Hum Genet 2011 0.94
50 Evidence that both genetic instability and selection contribute to the accumulation of chromosome alterations in cancer. Carcinogenesis 2005 0.93
51 Meta-analysis of 8q24 for seven cancers reveals a locus between NOV and ENPP2 associated with cancer development. BMC Med Genet 2011 0.90
52 Breast cancer risk polymorphisms and interaction with ionizing radiation among U.S. radiologic technologists. Cancer Epidemiol Biomarkers Prev 2008 0.90
53 Smoking water-pipe, chewing nass and prevalence of heart disease: a cross-sectional analysis of baseline data from the Golestan Cohort Study, Iran. Heart 2012 0.89
54 BRCA1 suppresses osteopontin-mediated breast cancer. J Biol Chem 2006 0.89
55 What ethical and legal principles should guide the genotyping of children as part of a personalised screening programme for common cancer? J Med Ethics 2013 0.85
56 Population-based screening in the era of genomics. Per Med 2012 0.84
57 Reducing salt intake in Iran: priorities and challenges. Arch Iran Med 2012 0.82
58 Stage shift in PSA-detected prostate cancers - effect modification by Gleason score. J Med Screen 2009 0.81
59 Polymorphisms in inflammation pathway genes and endometrial cancer risk. Cancer Epidemiol Biomarkers Prev 2012 0.81
60 Advocacy strategies and action plans for reducing salt intake in Iran. Arch Iran Med 2012 0.80
61 HSD17B1 genetic variants and hormone receptor-defined breast cancer. Cancer Epidemiol Biomarkers Prev 2008 0.80
62 Validation of a modelling approach for estimating the likely effectiveness of cancer screening using cancer data on prevalence screening and incidence. Cancer Epidemiol 2010 0.78
63 How not to interpret a P value? J Natl Cancer Inst 2007 0.78
64 Single nucleotide polymorphism (SNP) analysis demonstrates a significant association of tumour necrosis factor-alpha (TNFA) with primary immune thrombocytopenia among Caucasian adults. Hematology 2011 0.77
65 Association between KRAS rs61764370 and triple-negative breast cancer--a false positive? Lancet Oncol 2011 0.76
66 Outside the Box: Proactive care: the patient's right to choose. Br J Gen Pract 2013 0.75
67 Screening for ovarian cancer in women with varying levels of risk, using annual tests, results in high recall for repeat screening tests. Hered Cancer Clin Pract 2011 0.75
68 Any conclusion from this "citizens' jury" will be seriously flawed. BMJ 2012 0.75
69 Catastrophic failures of public health. Lancet 2004 0.75