| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Biological, clinical and population relevance of 95 loci for blood lipids.
|
Nature
|
2010
|
28.21
|
|
2
|
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.
|
Nat Genet
|
2010
|
23.08
|
|
3
|
Hundreds of variants clustered in genomic loci and biological pathways affect human height.
|
Nature
|
2010
|
20.01
|
|
4
|
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.
|
Nature
|
2011
|
13.25
|
|
5
|
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.
|
Nat Genet
|
2010
|
7.94
|
|
6
|
Population analysis of large copy number variants and hotspots of human genetic disease.
|
Am J Hum Genet
|
2009
|
6.79
|
|
7
|
Cardiovascular disease risk prediction with and without knowledge of genetic variation at chromosome 9p21.3.
|
Ann Intern Med
|
2009
|
6.00
|
|
8
|
Sugar-sweetened beverages and genetic risk of obesity.
|
N Engl J Med
|
2012
|
5.98
|
|
9
|
New loci associated with kidney function and chronic kidney disease.
|
Nat Genet
|
2010
|
5.58
|
|
10
|
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.
|
Nat Genet
|
2012
|
5.48
|
|
11
|
Inactivating mutations in NPC1L1 and protection from coronary heart disease.
|
N Engl J Med
|
2014
|
4.94
|
|
12
|
Multiple loci associated with indices of renal function and chronic kidney disease.
|
Nat Genet
|
2009
|
4.78
|
|
13
|
Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies.
|
Lancet
|
2012
|
4.63
|
|
14
|
Association between a literature-based genetic risk score and cardiovascular events in women.
|
JAMA
|
2010
|
4.46
|
|
15
|
Rationale, design, and methodology of the Women's Genome Health Study: a genome-wide association study of more than 25,000 initially healthy american women.
|
Clin Chem
|
2007
|
4.45
|
|
16
|
Loci related to metabolic-syndrome pathways including LEPR,HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study.
|
Am J Hum Genet
|
2008
|
4.31
|
|
17
|
Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease.
|
N Engl J Med
|
2016
|
3.88
|
|
18
|
Genome-wide association studies identify four ER negative-specific breast cancer risk loci.
|
Nat Genet
|
2013
|
3.81
|
|
19
|
Meta-analysis identifies six new susceptibility loci for atrial fibrillation.
|
Nat Genet
|
2012
|
3.71
|
|
20
|
Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.
|
Circulation
|
2011
|
3.68
|
|
21
|
Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein.
|
Am J Hum Genet
|
2008
|
3.61
|
|
22
|
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.
|
Nat Genet
|
2011
|
3.40
|
|
23
|
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies.
|
Nat Genet
|
2010
|
3.37
|
|
24
|
A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer.
|
Nat Genet
|
2011
|
3.37
|
|
25
|
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
|
Nat Genet
|
2013
|
3.25
|
|
26
|
Genetic variants at 2q24 are associated with susceptibility to type 2 diabetes.
|
Hum Mol Genet
|
2010
|
3.24
|
|
27
|
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.
|
PLoS Genet
|
2012
|
3.21
|
|
28
|
Genome-wide association studies identify loci associated with age at menarche and age at natural menopause.
|
Nat Genet
|
2009
|
3.06
|
|
29
|
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.
|
Nat Genet
|
2012
|
3.04
|
|
30
|
Common variants associated with plasma triglycerides and risk for coronary artery disease.
|
Nat Genet
|
2013
|
2.92
|
|
31
|
Novel association of ABO histo-blood group antigen with soluble ICAM-1: results of a genome-wide association study of 6,578 women.
|
PLoS Genet
|
2008
|
2.85
|
|
32
|
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits.
|
PLoS Genet
|
2013
|
2.83
|
|
33
|
FTO genotype is associated with phenotypic variability of body mass index.
|
Nature
|
2012
|
2.77
|
|
34
|
Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors.
|
Circ Cardiovasc Genet
|
2010
|
2.76
|
|
35
|
On the use of variance per genotype as a tool to identify quantitative trait interaction effects: a report from the Women's Genome Health Study.
|
PLoS Genet
|
2010
|
2.48
|
|
36
|
A statin-dependent QTL for GATM expression is associated with statin-induced myopathy.
|
Nature
|
2013
|
2.46
|
|
37
|
A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11.
|
Hum Mol Genet
|
2012
|
2.45
|
|
38
|
Genome-wide association of lipid-lowering response to statins in combined study populations.
|
PLoS One
|
2010
|
2.43
|
|
39
|
Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways.
|
Nat Genet
|
2012
|
2.12
|
|
40
|
Fried food consumption, genetic risk, and body mass index: gene-diet interaction analysis in three US cohort studies.
|
BMJ
|
2014
|
2.06
|
|
41
|
Novel genetic markers improve measures of atrial fibrillation risk prediction.
|
Eur Heart J
|
2013
|
1.93
|
|
42
|
A kinesin family member 6 variant is associated with coronary heart disease in the Women's Health Study.
|
J Am Coll Cardiol
|
2008
|
1.92
|
|
43
|
Polymorphism in the CETP gene region, HDL cholesterol, and risk of future myocardial infarction: Genomewide analysis among 18 245 initially healthy women from the Women's Genome Health Study.
|
Circ Cardiovasc Genet
|
2009
|
1.92
|
|
44
|
Discovery and replication of novel blood pressure genetic loci in the Women's Genome Health Study.
|
J Hypertens
|
2011
|
1.81
|
|
45
|
Rosuvastatin, proprotein convertase subtilisin/kexin type 9 concentrations, and LDL cholesterol response: the JUPITER trial.
|
Clin Chem
|
2011
|
1.79
|
|
46
|
Genome-wide meta-analysis identifies regions on 7p21 (AHR) and 15q24 (CYP1A2) as determinants of habitual caffeine consumption.
|
PLoS Genet
|
2011
|
1.77
|
|
47
|
Novel associations of CPS1, MUT, NOX4, and DPEP1 with plasma homocysteine in a healthy population: a genome-wide evaluation of 13 974 participants in the Women's Genome Health Study.
|
Circ Cardiovasc Genet
|
2009
|
1.71
|
|
48
|
Genome-wide association and functional follow-up reveals new loci for kidney function.
|
PLoS Genet
|
2012
|
1.68
|
|
49
|
Novel association of HK1 with glycated hemoglobin in a non-diabetic population: a genome-wide evaluation of 14,618 participants in the Women's Genome Health Study.
|
PLoS Genet
|
2008
|
1.67
|
|
50
|
Detection of protein folding defects caused by BRCA1-BRCT truncation and missense mutations.
|
J Biol Chem
|
2003
|
1.61
|
|
51
|
Association of hypertension drug target genes with blood pressure and hypertension in 86,588 individuals.
|
Hypertension
|
2011
|
1.60
|
|
52
|
Informed conditioning on clinical covariates increases power in case-control association studies.
|
PLoS Genet
|
2012
|
1.57
|
|
53
|
Tracing sub-structure in the European American population with PCA-informative markers.
|
PLoS Genet
|
2008
|
1.56
|
|
54
|
Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations.
|
Am J Hum Genet
|
2013
|
1.55
|
|
55
|
Novel loci, including those related to Crohn disease, psoriasis, and inflammation, identified in a genome-wide association study of fibrinogen in 17 686 women: the Women's Genome Health Study.
|
Circ Cardiovasc Genet
|
2009
|
1.51
|
|
56
|
Gene × physical activity interactions in obesity: combined analysis of 111,421 individuals of European ancestry.
|
PLoS Genet
|
2013
|
1.51
|
|
57
|
A genome-wide association study of early menopause and the combined impact of identified variants.
|
Hum Mol Genet
|
2013
|
1.50
|
|
58
|
Lifestyle interaction with fat mass and obesity-associated (FTO) genotype and risk of obesity in apparently healthy U.S. women.
|
Diabetes Care
|
2011
|
1.44
|
|
59
|
Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake.
|
Am J Clin Nutr
|
2013
|
1.35
|
|
60
|
Kinesin-like protein 6 (KIF6) polymorphism and the efficacy of rosuvastatin in primary prevention.
|
Circ Cardiovasc Genet
|
2011
|
1.32
|
|
61
|
Loci influencing blood pressure identified using a cardiovascular gene-centric array.
|
Hum Mol Genet
|
2013
|
1.27
|
|
62
|
Novel locus including FGF21 is associated with dietary macronutrient intake.
|
Hum Mol Genet
|
2013
|
1.27
|
|
63
|
A large-scale candidate gene association study of age at menarche and age at natural menopause.
|
Hum Genet
|
2010
|
1.22
|
|
64
|
Common variants in cardiac ion channel genes are associated with sudden cardiac death.
|
Circ Arrhythm Electrophysiol
|
2010
|
1.22
|
|
65
|
GOSR2 Lys67Arg is associated with hypertension in whites.
|
Am J Hypertens
|
2008
|
1.20
|
|
66
|
Genome-wide association study of relative telomere length.
|
PLoS One
|
2011
|
1.16
|
|
67
|
Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation.
|
Circulation
|
2014
|
1.11
|
|
68
|
Genome-wide association analysis of soluble ICAM-1 concentration reveals novel associations at the NFKBIK, PNPLA3, RELA, and SH2B3 loci.
|
PLoS Genet
|
2011
|
1.10
|
|
69
|
Genome-wide association study identifies variants at the IL18-BCO2 locus associated with interleukin-18 levels.
|
Arterioscler Thromb Vasc Biol
|
2010
|
1.10
|
|
70
|
Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.
|
Am J Clin Nutr
|
2013
|
1.08
|
|
71
|
Genome-wide linkage and association analyses implicate FASN in predisposition to Uterine Leiomyomata.
|
Am J Hum Genet
|
2012
|
1.08
|
|
72
|
Functional classification of proteins and protein variants.
|
Proc Natl Acad Sci U S A
|
2004
|
1.07
|
|
73
|
Large-scale candidate gene analysis of HDL particle features.
|
PLoS One
|
2011
|
1.04
|
|
74
|
The fat-mass and obesity-associated (FTO) gene, physical activity, and risk of incident cardiovascular events in white women.
|
Am Heart J
|
2010
|
1.03
|
|
75
|
Lack of association between SLCO1B1 polymorphisms and clinical myalgia following rosuvastatin therapy.
|
Am Heart J
|
2013
|
0.95
|
|
76
|
Purinergic receptor P2Y, G-protein coupled, 12 gene variants and risk of incident ischemic stroke, myocardial infarction, and venous thromboembolism.
|
Atherosclerosis
|
2007
|
0.93
|
|
77
|
Association of adiposity genetic variants with menarche timing in 92,105 women of European descent.
|
Am J Epidemiol
|
2013
|
0.93
|
|
78
|
Physical activity modifies the effect of LPL, LIPC, and CETP polymorphisms on HDL-C levels and the risk of myocardial infarction in women of European ancestry.
|
Circ Cardiovasc Genet
|
2011
|
0.91
|
|
79
|
Genetic variants of 11 telomere-pathway gene loci and the risk of incident type 2 diabetes mellitus: the Women's Genome Health Study.
|
Atherosclerosis
|
2011
|
0.89
|
|
80
|
Genetic variants in eleven telomere-associated genes and the risk of incident cardio/cerebrovascular disease: The Women's Genome Health Study.
|
Clin Chim Acta
|
2010
|
0.89
|
|
81
|
Pharmacogenetic determinants of statin-induced reductions in C-reactive protein.
|
Circ Cardiovasc Genet
|
2012
|
0.88
|
|
82
|
Mitochondrial uncoupling protein gene cluster variation (UCP2-UCP3) and the risk of incident type 2 diabetes mellitus: the Women's Genome Health Study.
|
Atherosclerosis
|
2010
|
0.88
|
|
83
|
DNA mismatch repair gene MSH6 implicated in determining age at natural menopause.
|
Hum Mol Genet
|
2013
|
0.88
|
|
84
|
Reproductive aging-associated common genetic variants and the risk of breast cancer.
|
Breast Cancer Res
|
2012
|
0.87
|
|
85
|
Cardiovascular risks associated with incident and prevalent periodontal disease.
|
J Clin Periodontol
|
2015
|
0.86
|
|
86
|
Prospective evaluation of B-type natriuretic peptide concentrations and the risk of type 2 diabetes in women.
|
Clin Chem
|
2013
|
0.84
|
|
87
|
Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.
|
Circ Cardiovasc Genet
|
2012
|
0.83
|
|
88
|
Genetics, ancestry, and hypertension: implications for targeted antihypertensive therapies.
|
Curr Hypertens Rep
|
2014
|
0.83
|
|
89
|
Currently available versions of genome-wide association studies cannot be used to query the common haptoglobin copy number variant.
|
J Am Coll Cardiol
|
2013
|
0.82
|
|
90
|
Common variants in Mendelian kidney disease genes and their association with renal function.
|
J Am Soc Nephrol
|
2013
|
0.82
|
|
91
|
Tumour necrosis factor gene polymorphisms and migraine: a systematic review and meta-analysis.
|
Cephalalgia
|
2011
|
0.81
|
|
92
|
An X chromosome association scan of the Norfolk Island genetic isolate provides evidence for a novel migraine susceptibility locus at Xq12.
|
PLoS One
|
2012
|
0.81
|
|
93
|
Genetic determinants of cardiovascular events among women with migraine: a genome-wide association study.
|
PLoS One
|
2011
|
0.79
|
|
94
|
Corrigendum: Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine.
|
Nat Genet
|
2016
|
0.77
|
|
95
|
Physical activity, genes for physical fitness, and risk of coronary heart disease.
|
Med Sci Sports Exerc
|
2013
|
0.77
|
|
96
|
Islet amyloid polypeptide gene variation (IAPP) and the risk of incident type 2 diabetes mellitus: the Women's Genome Health Study.
|
Clin Chim Acta
|
2011
|
0.76
|
|
97
|
Genetic variation of fifteen folate metabolic pathway associated gene loci and the risk of incident head and neck carcinoma: the Women's Genome Health Study.
|
Clin Chim Acta
|
2012
|
0.76
|
|
98
|
Lack of association between genetic variation in 9 innate immunity genes and baseline CRP levels.
|
Ann Hum Genet
|
2006
|
0.76
|
|
99
|
Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
|
PLoS Genet
|
2016
|
0.75
|
|
100
|
Age at natural menopause genetic risk score in relation to age at natural menopause and primary open-angle glaucoma in a US-based sample.
|
Menopause
|
2016
|
0.75
|
|
101
|
Correction: Selectivity in Genetic Association with Sub-classified Migraine in Women.
|
PLoS Genet
|
2015
|
0.75
|
|
102
|
Getting closer to p-selectin.
|
Clin Chem
|
2009
|
0.75
|
|
103
|
Genetics for monitoring prescription practices of commonly used drugs in populations.
|
Clin Chem
|
2011
|
0.75
|
|
104
|
Coronary heart disease risk, aspirin use, and apolipoprotein(a) 4399Met allele in the Atherosclerosis Risk in Communities (ARIC) study.
|
Thromb Haemost
|
2009
|
0.75
|
|
105
|
New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals.
|
Circ Cardiovasc Genet
|
2017
|
0.75
|
|
106
|
Corrigendum: Rare coding variants and X-linked loci associated with age at menarche.
|
Nat Commun
|
2015
|
0.75
|
|
107
|
Corrigendum: 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.
|
Sci Rep
|
2017
|
0.75
|
|
108
|
Tryptophanyl-tRNA synthetase gene polymorphisms and risk of incident myocardial infarction.
|
Atherosclerosis
|
2005
|
0.75
|
|
109
|
Corrigendum: Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.
|
Nat Genet
|
2017
|
0.75
|
|
110
|
Fish intake, genetic predisposition to alzheimer's disease and decline in global cognition and memory in five cohorts of older persons.
|
Am J Epidemiol
|
2017
|
0.75
|
|
111
|
Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.
|
Nat Genet
|
2017
|
0.75
|
|
112
|
Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.
|
PLoS Genet
|
2017
|
0.75
|