| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Newly identified loci that influence lipid concentrations and risk of coronary artery disease.
|
Nat Genet
|
2008
|
25.83
|
|
2
|
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.
|
Nat Genet
|
2010
|
23.08
|
|
3
|
Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits.
|
PLoS Genet
|
2007
|
14.99
|
|
4
|
Meta-analysis and imputation refines the association of 15q25 with smoking quantity.
|
Nat Genet
|
2010
|
8.55
|
|
5
|
Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia.
|
Proc Natl Acad Sci U S A
|
2008
|
5.27
|
|
6
|
Variants within the immunoregulatory CBLB gene are associated with multiple sclerosis.
|
Nat Genet
|
2010
|
4.69
|
|
7
|
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies.
|
Nat Genet
|
2010
|
3.37
|
|
8
|
The GLUT9 gene is associated with serum uric acid levels in Sardinia and Chianti cohorts.
|
PLoS Genet
|
2007
|
3.21
|
|
9
|
Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia.
|
Hum Mol Genet
|
2009
|
1.87
|
|
10
|
Genetic variants regulating immune cell levels in health and disease.
|
Cell
|
2013
|
1.86
|
|
11
|
Phosphodiesterase 8B gene variants are associated with serum TSH levels and thyroid function.
|
Am J Hum Genet
|
2008
|
1.77
|
|
12
|
Brain steroidogenesis mediates ethanol modulation of GABAA receptor activity in rat hippocampus.
|
J Neurosci
|
2004
|
1.71
|
|
13
|
Low-pass DNA sequencing of 1200 Sardinians reconstructs European Y-chromosome phylogeny.
|
Science
|
2013
|
1.70
|
|
14
|
A likelihood-based framework for variant calling and de novo mutation detection in families.
|
PLoS Genet
|
2012
|
1.57
|
|
15
|
Genotype calling and haplotyping in parent-offspring trios.
|
Genome Res
|
2012
|
1.27
|
|
16
|
Comparison of the effects of zaleplon, zolpidem, and triazolam at various GABA(A) receptor subtypes.
|
Eur J Pharmacol
|
2002
|
1.23
|
|
17
|
A genome-wide association scan on the levels of markers of inflammation in Sardinians reveals associations that underpin its complex regulation.
|
PLoS Genet
|
2012
|
1.23
|
|
18
|
Changes in GABA(A) receptor gene expression associated with selective alterations in receptor function and pharmacology after ethanol withdrawal.
|
J Neurosci
|
2003
|
1.15
|
|
19
|
Identification of a common variant in the TFR2 gene implicated in the physiological regulation of serum iron levels.
|
Hum Mol Genet
|
2010
|
1.03
|
|
20
|
Variants of the serotonin transporter gene and NEO-PI-R Neuroticism: No association in the BLSA and SardiNIA samples.
|
Am J Med Genet B Neuropsychiatr Genet
|
2009
|
1.01
|
|
21
|
Gamma-hydroxybutyric acid and diazepam antagonize a rapid increase in GABA(A) receptors alpha(4) subunit mRNA abundance induced by ethanol withdrawal in cerebellar granule cells.
|
Mol Pharmacol
|
2003
|
0.89
|
|
22
|
Distinct patterns of expression and regulation of GABA receptors containing the delta subunit in cerebellar granule and hippocampal neurons.
|
J Neurochem
|
2005
|
0.86
|
|
23
|
Synthesis and pharmacological evaluation of 1-[(1,2-diphenyl-1H-4-imidazolyl)methyl]-4-phenylpiperazines with clozapine-like mixed activities at dopamine D(2), serotonin, and GABA(A) receptors.
|
J Med Chem
|
2002
|
0.85
|
|
24
|
Low tolerance and dependence liabilities of etizolam: molecular, functional, and pharmacological correlates.
|
Eur J Pharmacol
|
2005
|
0.85
|
|
25
|
Molecular mechanisms of tolerance to and withdrawal of GABA(A) receptor modulators.
|
Eur Neuropsychopharmacol
|
2003
|
0.83
|
|
26
|
Inhibition by miltirone of up-regulation of GABAA receptor alpha4 subunit mRNA by ethanol withdrawal in hippocampal neurons.
|
Eur J Pharmacol
|
2004
|
0.80
|
|
27
|
Methods for association analysis and meta-analysis of rare variants in families.
|
Genet Epidemiol
|
2015
|
0.80
|
|
28
|
Correction: Assessing Mitochondrial DNA Variation and Copy Number in Lymphocytes of ~2,000 Sardinians Using Tailored Sequencing Analysis Tools.
|
PLoS Genet
|
2015
|
0.79
|
|
29
|
Ethyl 2-(4-bromophenyl)-1-(2,4-dichlorophenyl)-1H-4-imidazolecarboxylate is a novel positive modulator of GABAA receptors.
|
Eur J Pharmacol
|
2005
|
0.75
|
|
30
|
High affinity central benzodiazepine receptor ligands. Part 3: insights into the pharmacophore and pattern recognition study of intrinsic activities of pyrazolo[4,3-c]quinolin-3-ones.
|
Bioorg Med Chem
|
2003
|
0.75
|
|
31
|
Synthesis, structure-activity relationships at the GABA(A) receptor in rat brain, and differential electrophysiological profile at the recombinant human GABA(A) receptor of a series of substituted 1,2-diphenylimidazoles.
|
J Med Chem
|
2005
|
0.75
|
|
32
|
Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.
|
PLoS Genet
|
2017
|
0.75
|