Published in J Nutr on December 15, 2010
Branched-chain amino acids in metabolic signalling and insulin resistance. Nat Rev Endocrinol (2014) 1.71
Branched-chain amino acids, mitochondrial biogenesis, and healthspan: an evolutionary perspective. Aging (Albany NY) (2011) 1.09
Plasma Free Amino Acid Profiles Predict Four-Year Risk of Developing Diabetes, Metabolic Syndrome, Dyslipidemia, and Hypertension in Japanese Population. Sci Rep (2015) 0.89
Leucine supplementation protects from insulin resistance by regulating adiposity levels. PLoS One (2013) 0.89
Impact of nutrient excess and endothelial nitric oxide synthase on the plasma metabolite profile in mice. Front Physiol (2014) 0.86
Nutritional regulation of insulin secretion: implications for diabetes. Clin Biochem Rev (2012) 0.86
The effects of a multi-ingredient dietary supplement on body composition, adipokines, blood lipids, and metabolic health in overweight and obese men and women: a randomized controlled trial. J Int Soc Sports Nutr (2014) 0.80
Plasma metabolomic profiles in association with type 2 diabetes risk and prevalence in Chinese adults. Metabolomics (2015) 0.78
The Ratio of Dietary Branched-Chain Amino Acids is Associated with a Lower Prevalence of Obesity in Young Northern Chinese Adults: An Internet-Based Cross-Sectional Study. Nutrients (2015) 0.78
Reconstruction and analysis of correlation networks based on GC-MS metabolomics data for young hypertensive men. Anal Chim Acta (2014) 0.77
Associations between branched chain amino acid intake and biomarkers of adiposity and cardiometabolic health independent of genetic factors: A twin study. Int J Cardiol (2016) 0.76
Amino acid-induced impairment of insulin sensitivity in healthy and obese rats is reversible. Physiol Rep (2014) 0.76
Metabolomic and Lipidomic Analysis of Serum Samples following Curcuma longa Extract Supplementation in High-Fructose and Saturated Fat Fed Rats. PLoS One (2015) 0.76
Physical Activity Modifies the Association between Dietary Protein and Lean Mass of Postmenopausal Women. J Acad Nutr Diet (2016) 0.75
Postprandial Levels of Branch Chained and Aromatic Amino Acids Associate with Fasting Glycaemia. J Amino Acids (2016) 0.75
Chronic leucine supplementation improves lipid metabolism in C57BL/6J mice fed with a high-fat/cholesterol diet. Food Nutr Res (2016) 0.75
The role of dietary fat on the association between dietary amino acids and serum lipid profile in European adolescents participating in the HELENA Study. Eur J Clin Nutr (2014) 0.75
Metabolite Signatures of Metabolic Risk Factors and their Longitudinal Changes. J Clin Endocrinol Metab (2016) 0.75
Metabolic Profiling of Total Physical Activity and Sedentary Behavior in Community-Dwelling Men. PLoS One (2016) 0.75
Branched-Chain Amino Acid Supplementation in Combination with Voluntary Running Improves Body Composition in Female C57BL/6 Mice. J Diet Suppl (2015) 0.75
Leptin and the regulation of body weight in mammals. Nature (1998) 14.84
Comparison of weight-loss diets with different compositions of fat, protein, and carbohydrates. N Engl J Med (2009) 12.38
A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance. Cell Metab (2009) 11.46
A randomized trial of a low-carbohydrate diet for obesity. N Engl J Med (2003) 9.23
Hypothalamic mTOR signaling regulates food intake. Science (2006) 8.62
The epidemiology of overweight and obesity: public health crisis or moral panic? Int J Epidemiol (2005) 7.49
A high-protein diet induces sustained reductions in appetite, ad libitum caloric intake, and body weight despite compensatory changes in diurnal plasma leptin and ghrelin concentrations. Am J Clin Nutr (2005) 4.26
Insulin resistance is associated with a metabolic profile of altered protein metabolism in Chinese and Asian-Indian men. Diabetologia (2010) 2.99
Increasing dietary leucine intake reduces diet-induced obesity and improves glucose and cholesterol metabolism in mice via multimechanisms. Diabetes (2007) 2.85
INTERMAP: background, aims, design, methods, and descriptive statistics (nondietary). J Hum Hypertens (2003) 2.27
Nutrient intakes of middle-aged men and women in China, Japan, United Kingdom, and United States in the late 1990s: the INTERMAP study. J Hum Hypertens (2003) 2.25
Potential importance of leucine in treatment of obesity and the metabolic syndrome. J Nutr (2006) 2.13
Visceral adiposity and the risk of impaired glucose tolerance: a prospective study among Japanese Americans. Diabetes Care (2003) 2.10
Critical role for hypothalamic mTOR activity in energy balance. Cell Metab (2009) 1.90
INTERMAP: the dietary data--process and quality control. J Hum Hypertens (2003) 1.88
The role of leucine in weight loss diets and glucose homeostasis. J Nutr (2003) 1.86
Mobilization of visceral adipose tissue related to the improvement in insulin sensitivity in response to physical training in NIDDM. Effects of branched-chain amino acid supplements. Diabetes Care (1997) 1.83
Association between protein intake and blood pressure: the INTERMAP Study. Arch Intern Med (2006) 1.79
Association of monosodium glutamate intake with overweight in Chinese adults: the INTERMAP Study. Obesity (Silver Spring) (2008) 1.68
Retracted A central role for neuronal AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) in high-protein diet-induced weight loss. Diabetes (2007) 1.59
Regulation of leucine-stimulated insulin secretion and glutamine metabolism in isolated rat islets. J Biol Chem (2002) 1.53
Branched-chain amino acids activate key enzymes in protein synthesis after physical exercise. J Nutr (2006) 1.50
Leucine and protein synthesis: mTOR and beyond. Nutr Rev (2007) 1.43
Leucine in food mediates some of the postprandial rise in plasma leptin concentrations. Am J Physiol Endocrinol Metab (2006) 1.29
Leucine supplementation of drinking water does not alter susceptibility to diet-induced obesity in mice. J Nutr (2009) 1.28
Amino acid infusion increases the sensitivity of muscle protein synthesis in vivo to insulin. Effect of branched-chain amino acids. Biochem J (1988) 1.27
Effects of leucine supplementation on the body composition and protein status of rats submitted to food restriction. Nutrition (2006) 1.21
Increased dietary protein modifies glucose and insulin homeostasis in adult women during weight loss. J Nutr (2003) 1.21
Effects of high-protein, low-carbohydrate dieting on plasma lipoproteins and body weight. J Am Diet Assoc (1980) 1.14
Effect of high protein vs high carbohydrate intake on insulin sensitivity, body weight, hemoglobin A1c, and blood pressure in patients with type 2 diabetes mellitus. J Am Diet Assoc (2005) 1.14
Hypoglycemic effect of isoleucine involves increased muscle glucose uptake and whole body glucose oxidation and decreased hepatic gluconeogenesis. Am J Physiol Endocrinol Metab (2007) 1.11
Combined effects of caloric restriction and branched-chain amino acid supplementation on body composition and exercise performance in elite wrestlers. Int J Sports Med (1997) 1.10
A high-whey-protein diet reduces body weight gain and alters insulin sensitivity relative to red meat in wistar rats. J Nutr (2004) 1.03
Dose-dependent effects of central leptin gene therapy on genes that regulate body weight and appetite in the hypothalamus. Mol Ther (2001) 1.01
Impaired glucose signaling as a cause of obesity and the metabolic syndrome: the glucoadipostatic hypothesis. Physiol Behav (2005) 0.99
Isoleucine, a blood glucose-lowering amino acid, increases glucose uptake in rat skeletal muscle in the absence of increases in AMP-activated protein kinase activity. J Nutr (2005) 0.92
Whey protein isolate and glycomacropeptide decrease weight gain and alter body composition in male Wistar rats. Br J Nutr (2007) 0.83
Relationship between impaired glucose tolerance, non-insulin-dependent diabetes mellitus and obesity. Eur J Clin Invest (1998) 0.82
Effects of leucine on insulin secretion and beta cell membrane potential in mouse islets of Langerhans. Pancreas (1991) 0.78
Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trial. JAMA (2004) 23.69
Defining and setting national goals for cardiovascular health promotion and disease reduction: the American Heart Association's strategic Impact Goal through 2020 and beyond. Circulation (2010) 13.28
Low-fat dietary pattern and risk of cardiovascular disease: the Women's Health Initiative Randomized Controlled Dietary Modification Trial. JAMA (2006) 12.44
Calcium plus vitamin D supplementation and the risk of fractures. N Engl J Med (2006) 12.09
Diet and lifestyle recommendations revision 2006: a scientific statement from the American Heart Association Nutrition Committee. Circulation (2006) 11.65
Calcium plus vitamin D supplementation and the risk of colorectal cancer. N Engl J Med (2006) 8.73
Fast-food habits, weight gain, and insulin resistance (the CARDIA study): 15-year prospective analysis. Lancet (2005) 8.49
Major risk factors as antecedents of fatal and nonfatal coronary heart disease events. JAMA (2003) 7.35
Low-fat dietary pattern and risk of invasive breast cancer: the Women's Health Initiative Randomized Controlled Dietary Modification Trial. JAMA (2006) 6.51
Electron-beam tomography coronary artery calcium and cardiac events: a 37-month follow-up of 5635 initially asymptomatic low- to intermediate-risk adults. Circulation (2003) 6.13
Lifetime risks of cardiovascular disease. N Engl J Med (2012) 5.95
Dairy consumption, obesity, and the insulin resistance syndrome in young adults: the CARDIA Study. JAMA (2002) 5.44
Human metabolic phenotype diversity and its association with diet and blood pressure. Nature (2008) 5.41
Design and implementation of the Hispanic Community Health Study/Study of Latinos. Ann Epidemiol (2010) 4.61
Psychosocial factors and risk of hypertension: the Coronary Artery Risk Development in Young Adults (CARDIA) study. JAMA (2003) 4.07
Interventions to promote physical activity and dietary lifestyle changes for cardiovascular risk factor reduction in adults: a scientific statement from the American Heart Association. Circulation (2010) 3.63
Accumulated evidence on fish consumption and coronary heart disease mortality: a meta-analysis of cohort studies. Circulation (2004) 3.44
Longitudinal trends in diet and effects of sex, race, and education on dietary quality score change: the Coronary Artery Risk Development in Young Adults study. Am J Clin Nutr (2012) 3.38
Sodium, blood pressure, and cardiovascular disease: further evidence supporting the American Heart Association sodium reduction recommendations. Circulation (2012) 3.14
Mortality and cardiac and vascular outcomes in extremely obese women. JAMA (2006) 3.09
Low-fat dietary pattern and risk of colorectal cancer: the Women's Health Initiative Randomized Controlled Dietary Modification Trial. JAMA (2006) 2.97
Pulse pressure and cardiovascular disease-related mortality: follow-up study of the Multiple Risk Factor Intervention Trial (MRFIT). JAMA (2002) 2.96
Two-year follow-up results for Hip-Hop to Health Jr.: a randomized controlled trial for overweight prevention in preschool minority children. J Pediatr (2005) 2.85
Components of a cardioprotective diet: new insights. Circulation (2011) 2.81
Associations between recent exposure to ambient fine particulate matter and blood pressure in the Multi-ethnic Study of Atherosclerosis (MESA). Environ Health Perspect (2008) 2.80
Maintaining a high physical activity level over 20 years and weight gain. JAMA (2010) 2.78
Dietary sources of sodium in China, Japan, the United Kingdom, and the United States, women and men aged 40 to 59 years: the INTERMAP study. J Am Diet Assoc (2010) 2.60
Status of cardiovascular health in US adults: prevalence estimates from the National Health and Nutrition Examination Surveys (NHANES) 2003-2008. Circulation (2011) 2.54
Risk of cardiovascular disease by hysterectomy status, with and without oophorectomy: the Women's Health Initiative Observational Study. Circulation (2005) 2.49
Favorable cardiovascular risk profile in young women and long-term risk of cardiovascular and all-cause mortality. JAMA (2004) 2.45
Effect of calcium and vitamin D supplementation on blood pressure: the Women's Health Initiative Randomized Trial. Hypertension (2008) 2.44
Association of acculturation levels and prevalence of diabetes in the multi-ethnic study of atherosclerosis (MESA). Diabetes Care (2008) 2.44
Healthy lifestyle through young adulthood and the presence of low cardiovascular disease risk profile in middle age: the Coronary Artery Risk Development in (Young) Adults (CARDIA) study. Circulation (2012) 2.40
Midlife body mass index and hospitalization and mortality in older age. JAMA (2006) 2.36
Dietary recommendations for children and adolescents: a guide for practitioners. Pediatrics (2006) 2.36
Sugar-sweetened beverage, sugar intake of individuals, and their blood pressure: international study of macro/micronutrients and blood pressure. Hypertension (2011) 2.29
Prospective study of particulate air pollution exposures, subclinical atherosclerosis, and clinical cardiovascular disease: The Multi-Ethnic Study of Atherosclerosis and Air Pollution (MESA Air). Am J Epidemiol (2012) 2.23
A nutrient-wide association study on blood pressure. Circulation (2012) 2.19
Relation of BMI and physical activity to sex hormones in postmenopausal women. Obesity (Silver Spring) (2006) 2.17
Dietary recommendations for children and adolescents: a guide for practitioners: consensus statement from the American Heart Association. Circulation (2005) 2.16
Relation of iron and red meat intake to blood pressure: cross sectional epidemiological study. BMJ (2008) 2.09
Associations of plant food, dairy product, and meat intakes with 15-y incidence of elevated blood pressure in young black and white adults: the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Am J Clin Nutr (2005) 2.08
Soy protein, isoflavones, and cardiovascular health: an American Heart Association Science Advisory for professionals from the Nutrition Committee. Circulation (2006) 2.07
Evaluation and comparison of food records, recalls, and frequencies for energy and protein assessment by using recovery biomarkers. Am J Epidemiol (2011) 2.04
Race/ethnicity, income, major risk factors, and cardiovascular disease mortality. Am J Public Health (2005) 2.02
Risk factor burden in middle age and lifetime risks for cardiovascular and non-cardiovascular death (Chicago Heart Association Detection Project in Industry). Am J Cardiol (2006) 2.01
Fish consumption and incidence of stroke: a meta-analysis of cohort studies. Stroke (2004) 1.99
Favorable cardiovascular risk profile in middle age and health-related quality of life in older age. Arch Intern Med (2003) 1.84
Blood pressure differences between northern and southern Chinese: role of dietary factors: the International Study on Macronutrients and Blood Pressure. Hypertension (2004) 1.84
Prevalence of hypertension, awareness, treatment, and control in the Hispanic Community Health Study/Study of Latinos. Am J Hypertens (2014) 1.83
Relation of triglyceride levels, fasting and nonfasting, to fatal and nonfatal coronary heart disease. Arch Intern Med (2003) 1.82
Status of cardiovascular disease and stroke in Hispanics/Latinos in the United States: a science advisory from the American Heart Association. Circulation (2014) 1.81
The effects of a low-fat/high-fiber diet on sex hormone levels and menstrual cycling in premenopausal women: a 12-month randomized trial (the diet and hormone study). Cancer (2003) 1.81
Association between protein intake and blood pressure: the INTERMAP Study. Arch Intern Med (2006) 1.79
Assessment of analytical reproducibility of 1H NMR spectroscopy based metabonomics for large-scale epidemiological research: the INTERMAP Study. Anal Chem (2006) 1.76
Low-fat dietary pattern and lipoprotein risk factors: the Women's Health Initiative Dietary Modification Trial. Am J Clin Nutr (2010) 1.73
Relation of body mass index in young adulthood and middle age to Medicare expenditures in older age. JAMA (2004) 1.70
Consumption of monosodium glutamate in relation to incidence of overweight in Chinese adults: China Health and Nutrition Survey (CHNS). Am J Clin Nutr (2011) 1.68
Association of monosodium glutamate intake with overweight in Chinese adults: the INTERMAP Study. Obesity (Silver Spring) (2008) 1.68
Adherence to a healthy lifestyle and all-cause mortality in CKD. Clin J Am Soc Nephrol (2013) 1.64
Relationship of dietary cholesterol to blood pressure: the INTERMAP study. J Hypertens (2011) 1.63
Magnesium intake and risk of type 2 diabetes: meta-analysis of prospective cohort studies. Diabetes Care (2011) 1.63
Dietary starch intake of individuals and their blood pressure: the International Study of Macronutrients and Micronutrients and Blood Pressure. J Hypertens (2009) 1.61
Hip-Hop to Health Jr. for Latino preschool children. Obesity (Silver Spring) (2006) 1.61
Air Pollution and the microvasculature: a cross-sectional assessment of in vivo retinal images in the population-based multi-ethnic study of atherosclerosis (MESA). PLoS Med (2010) 1.59
Magnesium intake and incidence of metabolic syndrome among young adults. Circulation (2006) 1.57
Evaluation of measures of urinary albumin excretion in epidemiologic studies. Am J Epidemiol (2004) 1.54
Food omega-3 fatty acid intake of individuals (total, linolenic acid, long-chain) and their blood pressure: INTERMAP study. Hypertension (2007) 1.54
Estimating 24-hour urinary sodium excretion from casual urinary sodium concentrations in Western populations: the INTERSALT study. Am J Epidemiol (2013) 1.53
Summary of American Heart Association Diet and Lifestyle Recommendations revision 2006. Arterioscler Thromb Vasc Biol (2006) 1.53
Association of sodium and potassium intake with left ventricular mass: coronary artery risk development in young adults. Hypertension (2011) 1.52
Venous thrombosis and conjugated equine estrogen in women without a uterus. Arch Intern Med (2006) 1.50
Sleep-disordered breathing in Hispanic/Latino individuals of diverse backgrounds. The Hispanic Community Health Study/Study of Latinos. Am J Respir Crit Care Med (2014) 1.49