Published in EMBO J on October 01, 1990
Arabidopsis FAD2 gene encodes the enzyme that is essential for polyunsaturated lipid synthesis. Plant Cell (1994) 4.72
Membrane protein sorting in the yeast secretory pathway: evidence that the vacuole may be the default compartment. J Cell Biol (1992) 4.20
Retrieval of transmembrane proteins to the endoplasmic reticulum. J Cell Biol (1993) 3.67
Signal-mediated retrieval of a membrane protein from the Golgi to the ER in yeast. J Cell Biol (1994) 3.32
Human cytomegalovirus inhibits antigen presentation by a sequential multistep process. Proc Natl Acad Sci U S A (1996) 3.16
Cloning of higher plant omega-3 fatty acid desaturases. Plant Physiol (1993) 3.05
An endoplasmic reticulum-retained herpes simplex virus glycoprotein H is absent from secreted virions: evidence for reenvelopment during egress. J Virol (1996) 2.98
Genetic dissection of polyunsaturated fatty acid synthesis in Caenorhabditis elegans. Proc Natl Acad Sci U S A (2002) 2.89
Rab6 coordinates a novel Golgi to ER retrograde transport pathway in live cells. J Cell Biol (1999) 2.85
The long cytoplasmic tail of gp41 is required in a cell type-dependent manner for HIV-1 envelope glycoprotein incorporation into virions. Proc Natl Acad Sci U S A (2000) 2.70
An N-terminal double-arginine motif maintains type II membrane proteins in the endoplasmic reticulum. EMBO J (1994) 2.65
Kin recognition between medial Golgi enzymes in HeLa cells. EMBO J (1994) 2.62
gp25L/emp24/p24 protein family members of the cis-Golgi network bind both COP I and II coatomer. J Cell Biol (1998) 2.56
The membrane spanning domain of beta-1,4-galactosyltransferase specifies trans Golgi localization. EMBO J (1991) 2.46
Crimean-Congo hemorrhagic fever virus genomics and global diversity. J Virol (2006) 2.39
Identification of an animal omega-3 fatty acid desaturase by heterologous expression in Arabidopsis. Proc Natl Acad Sci U S A (1997) 2.31
The Golgi-localization of yeast Emp47p depends on its di-lysine motif but is not affected by the ret1-1 mutation in alpha-COP. J Cell Biol (1995) 2.26
An integral membrane component of coatomer-coated transport vesicles defines a family of proteins involved in budding. Proc Natl Acad Sci U S A (1995) 2.26
A major transmembrane protein of Golgi-derived COPI-coated vesicles involved in coatomer binding. J Cell Biol (1996) 2.20
Membrane protein retention in the yeast Golgi apparatus: dipeptidyl aminopeptidase A is retained by a cytoplasmic signal containing aromatic residues. J Cell Biol (1993) 2.15
The TGN38 glycoprotein contains two non-overlapping signals that mediate localization to the trans-Golgi network. J Cell Biol (1994) 2.11
Antagonism of Beclin 1-dependent autophagy by BCL-2 at the endoplasmic reticulum requires NAF-1. EMBO J (2009) 2.08
Tomato Ve disease resistance genes encode cell surface-like receptors. Proc Natl Acad Sci U S A (2001) 2.03
Localization of a yeast early Golgi mannosyltransferase, Och1p, involves retrograde transport. J Cell Biol (1996) 2.03
Involvement of the transmembrane protein p23 in biosynthetic protein transport. J Cell Biol (1997) 2.00
Regulation of G protein-coupled receptor export trafficking. Biochim Biophys Acta (2006) 1.99
Molecular cloning and characterization of the yeast gene for squalene synthetase. Proc Natl Acad Sci U S A (1991) 1.98
A jojoba beta-Ketoacyl-CoA synthase cDNA complements the canola fatty acid elongation mutation in transgenic plants. Plant Cell (1996) 1.95
Sorting of Golgi resident proteins into different subpopulations of COPI vesicles: a role for ArfGAP1. J Cell Biol (2001) 1.89
The glucose-6-phosphatase system. Biochem J (2002) 1.87
A novel membrane-associated metalloprotease, Ste24p, is required for the first step of NH2-terminal processing of the yeast a-factor precursor. J Cell Biol (1997) 1.87
p59fyn tyrosine kinase associates with multiple T-cell receptor subunits through its unique amino-terminal domain. Mol Cell Biol (1992) 1.87
Targeting of cholera toxin and Escherichia coli heat labile toxin in polarized epithelia: role of COOH-terminal KDEL. J Cell Biol (1995) 1.86
Signals for retention of transmembrane proteins in the endoplasmic reticulum studied with CD4 truncation mutants. Proc Natl Acad Sci U S A (1991) 1.86
A sorting motif localizes the foamy virus glycoprotein to the endoplasmic reticulum. J Virol (1997) 1.85
Identification of a calmodulin-regulated Ca2+-ATPase in the endoplasmic reticulum. Plant Physiol (1999) 1.84
The ion channel activity of the influenza virus M2 protein affects transport through the Golgi apparatus. J Cell Biol (1996) 1.83
Isolation, characterization, and expression of cDNAs encoding murine alpha-mannosidase II, a Golgi enzyme that controls conversion of high mannose to complex N-glycans. J Cell Biol (1991) 1.83
Endoplasmic reticulum localization of Sec12p is achieved by two mechanisms: Rer1p-dependent retrieval that requires the transmembrane domain and Rer1p-independent retention that involves the cytoplasmic domain. J Cell Biol (1996) 1.82
Erp1p and Erp2p, partners for Emp24p and Erv25p in a yeast p24 complex. Mol Biol Cell (1999) 1.80
Vma21p is a yeast membrane protein retained in the endoplasmic reticulum by a di-lysine motif and is required for the assembly of the vacuolar H(+)-ATPase complex. Mol Biol Cell (1994) 1.73
Genes that allow yeast cells to grow in the absence of the HDEL receptor. EMBO J (1992) 1.73
Proteasomes are regulated by interferon gamma: implications for antigen processing. Proc Natl Acad Sci U S A (1992) 1.73
Role of a new mammalian gene family in the biosynthesis of very long chain fatty acids and sphingolipids. J Cell Biol (2000) 1.70
Rer1p, a retrieval receptor for endoplasmic reticulum membrane proteins, is dynamically localized to the Golgi apparatus by coatomer. J Cell Biol (2001) 1.67
COPI-mediated transport. J Membr Biol (2006) 1.66
Yeast Kex1p is a Golgi-associated membrane protein: deletions in a cytoplasmic targeting domain result in mislocalization to the vacuolar membrane. J Cell Biol (1992) 1.66
The amino-terminal domain of the lamin B receptor is a nuclear envelope targeting signal. J Cell Biol (1993) 1.66
Analysis of endoplasmic reticulum trafficking signals by combinatorial screening in mammalian cells. Proc Natl Acad Sci U S A (2001) 1.65
Yeast Gaa1p is required for attachment of a completed GPI anchor onto proteins. J Cell Biol (1995) 1.64
The novel ER membrane protein PRO41 is essential for sexual development in the filamentous fungus Sordaria macrospora. Mol Microbiol (2007) 1.63
Activation of transcription factor NF-kappaB by the adenovirus E3/19K protein requires its ER retention. J Cell Biol (1996) 1.62
Cloning of a coconut endosperm cDNA encoding a 1-acyl-sn-glycerol-3-phosphate acyltransferase that accepts medium-chain-length substrates. Plant Physiol (1995) 1.61
Delta- and zeta-COP, two coatomer subunits homologous to clathrin-associated proteins, are involved in ER retrieval. EMBO J (1996) 1.61
Mutational analysis of the human KDEL receptor: distinct structural requirements for Golgi retention, ligand binding and retrograde transport. EMBO J (1993) 1.60
COOH-terminal sequence motifs target the T cell protein tyrosine phosphatase to the ER and nucleus. J Cell Biol (1995) 1.60
The single transmembrane segment of gp210 is sufficient for sorting to the pore membrane domain of the nuclear envelope. J Cell Biol (1992) 1.58
Sorting by COP I-coated vesicles under interphase and mitotic conditions. J Cell Biol (1996) 1.58
Immunocytochemical analysis of the transfer of vesicular stomatitis virus G glycoprotein from the intermediate compartment to the Golgi complex. J Cell Biol (1992) 1.58
Retention of adenovirus E19 glycoprotein in the endoplasmic reticulum is essential to its ability to block antigen presentation. J Exp Med (1991) 1.55
Erv41p and Erv46p: new components of COPII vesicles involved in transport between the ER and Golgi complex. J Cell Biol (2001) 1.50
Cytoplasmic domain of P-selectin (CD62) contains the signal for sorting into the regulated secretory pathway. Mol Biol Cell (1992) 1.48
Rer1p, a retrieval receptor for ER membrane proteins, recognizes transmembrane domains in multiple modes. Mol Biol Cell (2003) 1.48
Identification of a gene required for membrane protein retention in the early secretory pathway. Proc Natl Acad Sci U S A (1993) 1.48
The capacity to retrieve escaped ER proteins extends to the trans-most cisterna of the Golgi stack. J Cell Biol (1995) 1.45
Rer1p as common machinery for the endoplasmic reticulum localization of membrane proteins. Proc Natl Acad Sci U S A (1997) 1.43
The yeast RER2 gene, identified by endoplasmic reticulum protein localization mutations, encodes cis-prenyltransferase, a key enzyme in dolichol synthesis. Mol Cell Biol (1999) 1.42
Mannose 6-phosphate receptors regulate the formation of clathrin-coated vesicles in the TGN. J Cell Biol (1997) 1.41
Endoplasmic reticulum export of glycosyltransferases depends on interaction of a cytoplasmic dibasic motif with Sar1. Mol Biol Cell (2003) 1.41
Molecular identity and cellular distribution of advanced glycation endproduct receptors: relationship of p60 to OST-48 and p90 to 80K-H membrane proteins. Proc Natl Acad Sci U S A (1996) 1.40
Toxin entry: retrograde transport through the secretory pathway. J Cell Biol (1998) 1.38
Mistargeting of the lectin ERGIC-53 to the endoplasmic reticulum of HeLa cells impairs the secretion of a lysosomal enzyme. J Cell Biol (1998) 1.37
Targeting of protein ERGIC-53 to the ER/ERGIC/cis-Golgi recycling pathway. J Cell Biol (1995) 1.37
The Saccharomyces cerevisiae prenylcysteine carboxyl methyltransferase Ste14p is in the endoplasmic reticulum membrane. Mol Biol Cell (1998) 1.36
The KDEL receptor mediates a retrieval mechanism that contributes to quality control at the endoplasmic reticulum. EMBO J (2001) 1.35
Membrane protein retrieval from the Golgi apparatus to the endoplasmic reticulum (ER): characterization of the RER1 gene product as a component involved in ER localization of Sec12p. Mol Biol Cell (1995) 1.34
PIG-M transfers the first mannose to glycosylphosphatidylinositol on the lumenal side of the ER. EMBO J (2001) 1.34
Kex2-dependent invertase secretion as a tool to study the targeting of transmembrane proteins which are involved in ER-->Golgi transport in yeast. EMBO J (1994) 1.32
Characterization of the genome of feline foamy virus and its proteins shows distinct features different from those of primate spumaviruses. J Virol (1997) 1.32
Steric masking of a dilysine endoplasmic reticulum retention motif during assembly of the human high affinity receptor for immunoglobulin E. J Cell Biol (1995) 1.32
Conservation between human and fungal squalene synthetases: similarities in structure, function, and regulation. Mol Cell Biol (1993) 1.31
Assembly of the coronavirus envelope: homotypic interactions between the M proteins. J Virol (2000) 1.30
Functional analysis of a de novo GRIN2A missense mutation associated with early-onset epileptic encephalopathy. Nat Commun (2014) 1.29
Myristylation is involved in intracellular retention of hepatitis B virus envelope proteins. J Virol (1991) 1.29
The C-terminal dilysine motif confers endoplasmic reticulum localization to type I membrane proteins in plants. Plant Cell (2000) 1.29
A gene on chromosome 11q23 coding for a putative glucose- 6-phosphate translocase is mutated in glycogen-storage disease types Ib and Ic. Am J Hum Genet (1998) 1.28
The luminal part of the murine cytomegalovirus glycoprotein gp40 catalyzes the retention of MHC class I molecules. EMBO J (2000) 1.28
Mechanisms of T-cell activation by human T-cell lymphotropic virus type I. Microbiol Mol Biol Rev (1999) 1.27
Carboxy terminally truncated forms of ribophorin I are degraded in pre-Golgi compartments by a calcium-dependent process. J Cell Biol (1992) 1.26
Two endoplasmic reticulum (ER) membrane proteins that facilitate ER-to-Golgi transport of glycosylphosphatidylinositol-anchored proteins. Mol Biol Cell (1999) 1.24
Distinct processes mediate glycoprotein and glycopeptide export from the endoplasmic reticulum in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1992) 1.24
The MHC class I antigen presentation pathway: strategies for viral immune evasion. Immunology (2003) 1.24
The molecular chaperone calnexin is expressed on the surface of immature thymocytes in association with clonotype-independent CD3 complexes. EMBO J (1995) 1.24
Retention of p63 in an ER-Golgi intermediate compartment depends on the presence of all three of its domains and on its ability to form oligomers. J Cell Biol (1994) 1.24
Intracellular targeting signals contribute to localization of coronavirus spike proteins near the virus assembly site. J Virol (2004) 1.23
Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science (1988) 220.77
Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma. J Cell Biol (1975) 36.95
A C-terminal signal prevents secretion of luminal ER proteins. Cell (1987) 14.83
Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: evidence for membrane cycling from Golgi to ER. Cell (1989) 13.41
IgG or IgM monoclonal antibodies reactive with different determinants on the molecular complex bearing Lyt 2 antigen block T cell-mediated cytolysis in the absence of complement. J Immunol (1980) 10.30
Biosynthetic protein transport and sorting by the endoplasmic reticulum and Golgi. Annu Rev Biochem (1987) 10.25
The isolation and nucleotide sequence of a cDNA encoding the T cell surface protein T4: a new member of the immunoglobulin gene family. Cell (1985) 7.16
A conserved tripeptide sorts proteins to peroxisomes. J Cell Biol (1989) 6.59
NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor. J Biol Chem (1990) 5.91
Assembly of influenza hemagglutinin trimers and its role in intracellular transport. J Cell Biol (1986) 4.93
The rate of bulk flow from the endoplasmic reticulum to the cell surface. Cell (1987) 4.82
Brefeldin A redistributes resident and itinerant Golgi proteins to the endoplasmic reticulum. J Cell Biol (1989) 4.81
Evidence that luminal ER proteins are sorted from secreted proteins in a post-ER compartment. EMBO J (1988) 4.80
Regulation of protein export from the endoplasmic reticulum. Annu Rev Cell Biol (1988) 4.53
Short cytoplasmic sequences serve as retention signals for transmembrane proteins in the endoplasmic reticulum. Cell (1989) 4.47
Control of topology and mode of assembly of a polytopic membrane protein by positively charged residues. Nature (1989) 4.45
Nucleotide sequence of the EcoRI D fragment of adenovirus 2 genome. Nucleic Acids Res (1980) 4.34
Specificity of binding of clathrin adaptors to signals on the mannose-6-phosphate/insulin-like growth factor II receptor. EMBO J (1989) 4.17
A soluble CD4 protein selectively inhibits HIV replication and syncytium formation. Nature (1988) 4.15
The isolation and sequence of the gene encoding T8: a molecule defining functional classes of T lymphocytes. Cell (1985) 3.91
Simple and rapid measurement of human T lymphocytes and their subclasses in peripheral blood. Proc Natl Acad Sci U S A (1980) 2.96
In vivo chemical modification of proteins (post-translational modification). Annu Rev Biochem (1981) 2.91
Human 3-hydroxy-3-methylglutaryl coenzyme A reductase. Conserved domains responsible for catalytic activity and sterol-regulated degradation. J Biol Chem (1985) 2.90
A short sequence in the COOH-terminus makes an adenovirus membrane glycoprotein a resident of the endoplasmic reticulum. Cell (1987) 2.88
Immunochemical analysis of rough and smooth microsomes from rat liver. Segregation of docking protein in rough membranes. Eur J Biochem (1985) 2.78
Clathrin: a role in the intracellular retention of a Golgi membrane protein. Science (1989) 2.75
Nucleotide sequence of 3-hydroxy-3-methyl-glutaryl coenzyme A reductase, a glycoprotein of endoplasmic reticulum. Nature (1984) 2.66
Appearance of crystalloid endoplasmic reticulum in compactin-resistant Chinese hamster cells with a 500-fold increase in 3-hydroxy-3-methylglutaryl-coenzyme A reductase. Proc Natl Acad Sci U S A (1982) 2.58
Human ribophorins I and II: the primary structure and membrane topology of two highly conserved rough endoplasmic reticulum-specific glycoproteins. EMBO J (1987) 2.53
Peroxisome targeting signal of rat liver acyl-coenzyme A oxidase resides at the carboxy terminus. Mol Cell Biol (1989) 2.33
Protein transport. Signals and salvage sequences. Nature (1987) 2.24
DNA sequence of the early E3 transcription unit of adenovirus 5. Virology (1985) 2.17
ERp99, an abundant, conserved glycoprotein of the endoplasmic reticulum, is homologous to the 90-kDa heat shock protein (hsp90) and the 94-kDa glucose regulated protein (GRP94). J Biol Chem (1987) 2.09
Novel N-terminal amino acid sequence required for retention of a hepatitis B virus glycoprotein in the endoplasmic reticulum. Mol Cell Biol (1989) 2.05
Defining lipid transport pathways in animal cells. Science (1985) 2.00
Cloning of a human liver microsomal UDP-glucuronosyltransferase cDNA. Biochem J (1987) 1.97
Increase in membrane cholesterol: a possible trigger for degradation of HMG CoA reductase and crystalloid endoplasmic reticulum in UT-1 cells. Cell (1984) 1.55
Molecular cloning of Lyt-2, a membrane glycoprotein marking a subset of mouse T lymphocytes: molecular homology to its human counterpart, Leu-2/T8, and to immunoglobulin variable regions. Proc Natl Acad Sci U S A (1985) 1.53
The signal peptide of the rotavirus glycoprotein VP7 is essential for its retention in the ER as an integral membrane protein. Cell (1989) 1.47
Region E3 of human adenoviruses; differences between the oncogenic adenovirus-3 and the non-oncogenic adenovirus-2. Gene (1986) 1.39
cDNA-derived primary structure of the glycoprotein component of canine microsomal signal peptidase complex. J Biol Chem (1988) 1.19
Rat liver UDP-glucuronosyltransferase. Sequence and expression of a cDNA encoding a phenobarbital-inducible form. J Biol Chem (1986) 1.17
Cloning and characterization of cDNA encoding 3-methylcholanthrene inducible rat mRNA for UDP-glucuronosyltransferase. J Biol Chem (1986) 1.17
Cloning and substrate specificity of a human phenol UDP-glucuronosyltransferase expressed in COS-7 cells. Proc Natl Acad Sci U S A (1988) 1.16
The G protein of vesicular stomatitis virus has free access into and egress from the smooth endoplasmic reticulum of UT-1 cells. J Cell Biol (1990) 1.05
Molecular cloning and expression of cDNA encoding the 53,000-dalton glycoprotein of rabbit skeletal muscle sarcoplasmic reticulum. J Biol Chem (1989) 1.03
The full length coding sequence of rat liver androsterone UDP-glucuronyltransferase cDNA and comparison with other members of this gene family. Nucleic Acids Res (1986) 1.03
Endoplasmin is a reticuloplasmin. J Cell Sci (1988) 1.02
Mouse UDP glucuronosyltransferase. cDNA and complete amino acid sequence and regulation. Eur J Biochem (1987) 0.98
Molecular cloning of the a1 locus of Zea mays using the transposable elements En and Mu1. EMBO J (1985) 6.97
Overexpression of the dynamitin (p50) subunit of the dynactin complex disrupts dynein-dependent maintenance of membrane organelle distribution. J Cell Biol (1997) 6.57
Characterization of a cis-Golgi matrix protein, GM130. J Cell Biol (1995) 6.22
The regulatory c1 locus of Zea mays encodes a protein with homology to myb proto-oncogene products and with structural similarities to transcriptional activators. EMBO J (1987) 5.98
An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex. Science (1996) 5.93
Crystal structures of two viral peptides in complex with murine MHC class I H-2Kb. Science (1992) 4.74
Short cytoplasmic sequences serve as retention signals for transmembrane proteins in the endoplasmic reticulum. Cell (1989) 4.47
The Spm (En) transposable element controls the excision of a 2-kb DNA insert at the wx allele of Zea mays. EMBO J (1984) 4.41
Crystal structure of mouse CD1: An MHC-like fold with a large hydrophobic binding groove. Science (1997) 4.27
A viral inhibitor of peptide transporters for antigen presentation. Nature (1995) 4.26
Influence of transposable elements on the structure and function of the A1 gene of Zea mays. EMBO J (1987) 4.23
Plant transposable elements generate the DNA sequence diversity needed in evolution. EMBO J (1985) 4.12
2 -Microglobulin--a free immunoglobulin domain. Proc Natl Acad Sci U S A (1972) 3.74
Retrieval of transmembrane proteins to the endoplasmic reticulum. J Cell Biol (1993) 3.67
Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen. Science (1998) 3.64
Emerging principles for the recognition of peptide antigens by MHC class I molecules. Science (1992) 3.64
Impaired intracellular transport of class I MHC antigens as a possible means for adenoviruses to evade immune surveillance. Cell (1985) 3.59
Epidermal Langerhans cells express Ia antigens. Nature (1977) 3.51
Membrane insertion and oligomeric assembly of HLA-DR histocompatibility antigens. Cell (1982) 3.36
Intracellular transport of class II MHC molecules directed by invariant chain. Nature (1990) 3.35
Recycling of golgi-resident glycosyltransferases through the ER reveals a novel pathway and provides an explanation for nocodazole-induced Golgi scattering. J Cell Biol (1998) 3.31
Complete amino acid sequence of an HLA-DR antigen-like beta chain as predicted from the nucleotide sequence: similarities with immunoglobulins and HLA-A, -B, and -C antigens. Proc Natl Acad Sci U S A (1982) 3.30
Genetic and molecular analysis of the Enhancer (En) transposable element system of Zea mays. EMBO J (1985) 3.28
Molecular cloning of the c locus of Zea mays: a locus regulating the anthocyanin pathway. EMBO J (1986) 3.18
Human cytomegalovirus inhibits antigen presentation by a sequential multistep process. Proc Natl Acad Sci U S A (1996) 3.16
N-acetyltransferase phenotype and risk in urinary bladder cancer: approaches in molecular epidemiology. Preliminary results in Sweden and Denmark. Environmental Health Perspectives;1979:71-79. Int J Epidemiol (2007) 3.13
CD8 enhances formation of stable T-cell receptor/MHC class I molecule complexes. Nature (1996) 3.08
Mapping the distribution of Golgi enzymes involved in the construction of complex oligosaccharides. J Cell Sci (1995) 2.98
beta-Amyloid(1-42) binds to alpha7 nicotinic acetylcholine receptor with high affinity. Implications for Alzheimer's disease pathology. J Biol Chem (2000) 2.96
The ER-luminal domain of the HCMV glycoprotein US6 inhibits peptide translocation by TAP. Immunity (1997) 2.93
Use of anti-idiotypic antibodies as cell-surface receptor probes. Proc Natl Acad Sci U S A (1978) 2.92
A short sequence in the COOH-terminus makes an adenovirus membrane glycoprotein a resident of the endoplasmic reticulum. Cell (1987) 2.88
The three-dimensional structure of retinol-binding protein. EMBO J (1984) 2.82
DNA microarrays of the complex human cytomegalovirus genome: profiling kinetic class with drug sensitivity of viral gene expression. J Virol (1999) 2.80
TCR-Mediated internalization of peptide-MHC complexes acquired by T cells. Science (1999) 2.70
cDNA clone for the human invariant gamma chain of class II histocompatibility antigens and its implications for the protein structure. Proc Natl Acad Sci U S A (1983) 2.66
Highly purified papain-solubilized HL-A antigens contain beta2-microglobulin. Proc Natl Acad Sci U S A (1974) 2.66
An N-terminal double-arginine motif maintains type II membrane proteins in the endoplasmic reticulum. EMBO J (1994) 2.65
Molecular mechanism and species specificity of TAP inhibition by herpes simplex virus ICP47. EMBO J (1996) 2.64
gp25L/emp24/p24 protein family members of the cis-Golgi network bind both COP I and II coatomer. J Cell Biol (1998) 2.56
The complete amino acid sequence of beta 2-microglobulin. Biochemistry (1973) 2.55
Evidence for a COP-I-independent transport route from the Golgi complex to the endoplasmic reticulum. Nat Cell Biol (1999) 2.54
Structure of the murine immune response I-A beta locus: sequence of the I-A beta gene and an adjacent beta-chain second domain exon. Cell (1983) 2.42
Kinetics and affinity of reactions between an antigen-specific T cell receptor and peptide-MHC complexes. Immunity (1994) 2.39
Peptide binding and presentation by mouse CD1. Science (1995) 2.38
Sexual conflict promotes speciation in insects. Proc Natl Acad Sci U S A (2000) 2.37
Mutations and selection in the generation of class II histocompatibility antigen polymorphism. EMBO J (1984) 2.34
The molecular chaperone calnexin binds Glc1Man9GlcNAc2 oligosaccharide as an initial step in recognizing unfolded glycoproteins. J Biol Chem (1995) 2.31
GTP hydrolysis by arf-1 mediates sorting and concentration of Golgi resident enzymes into functional COP I vesicles. EMBO J (1999) 2.30
Four secretory proteins synthesized by hepatocytes are transported from endoplasmic reticulum to Golgi complex at different rates. EMBO J (1984) 2.27
Increased mortality in COPD among construction workers exposed to inorganic dust. Eur Respir J (2004) 2.22
Both alpha and beta chains of HLA-DC class II histocompatibility antigens display extensive polymorphism in their amino-terminal domains. EMBO J (1984) 2.18
Maize transposable elements. Annu Rev Genet (1989) 2.14
Alpha chain of HLA-DR transplantation antigens is a member of the same protein superfamily as the immunoglobulins. Cell (1982) 2.13
The TGN38 glycoprotein contains two non-overlapping signals that mediate localization to the trans-Golgi network. J Cell Biol (1994) 2.11
Invariant chain distinguishes between the exogenous and endogenous antigen presentation pathways. Nature (1990) 2.11
High-affinity reactions between antigen-specific T-cell receptors and peptides associated with allogeneic and syngeneic major histocompatibility complex class I proteins. Proc Natl Acad Sci U S A (1994) 2.09
Antigen presentation and T cell development in H2-M-deficient mice. Science (1996) 2.07
Evidence that neurones accumulating amyloid can undergo lysis to form amyloid plaques in Alzheimer's disease. Histopathology (2001) 2.07
Localization of the Lys, Asp, Glu, Leu tetrapeptide receptor to the Golgi complex and the intermediate compartment in mammalian cells. J Cell Biol (1994) 2.04
The cell attachment domain of fibronectin. Determination of the primary structure. J Biol Chem (1982) 2.03
[Treatment of neonatal hyperbilirubinemia with BiliBed]. Tidsskr Nor Laegeforen (1999) 2.02
The En/Spm transposable element of Zea mays contains splice sites at the termini generating a novel intron from a dSpm element in the A2 gene. EMBO J (1990) 2.00
HLA-D region beta-chain DNA endonuclease fragments differ between HLA-DR identical healthy and insulin-dependent diabetic individuals. Nature (1983) 1.99
Differentiation of glomerular, tubular, and normal proteinuria: determinations of urinary excretion of beta-2-macroglobulin, albumin, and total protein. J Clin Invest (1969) 1.97
Role of beta2-microglobulin in the intracellular processing of HLA antigens. Biochemistry (1981) 1.96
Molecular association between transplantation antigens and cell surface antigen in adenovirus-transformed cell line. Proc Natl Acad Sci U S A (1978) 1.94
Structure of C-terminal half of two H-2 antigens from cloned mRNA. Nature (1981) 1.90
Hormonal regulation of the expression of Ia antigens on mammary gland epithelium. Eur J Immunol (1980) 1.90
cDNA clone coding for part of a mouse H-2d major histocompatibility antigen. Proc Natl Acad Sci U S A (1981) 1.90
Sorting of Golgi resident proteins into different subpopulations of COPI vesicles: a role for ArfGAP1. J Cell Biol (2001) 1.89
T cells can use either T cell receptor or CD28 receptors to absorb and internalize cell surface molecules derived from antigen-presenting cells. J Exp Med (2000) 1.88
Isolation of a matrix that binds medial Golgi enzymes. J Cell Biol (1994) 1.87
Exon-intron organization and complete nucleotide sequence of a human major histocompatibility antigen DC beta gene. Proc Natl Acad Sci U S A (1983) 1.85
Colonisation of pregnant and puerperal women and neonates with Chlamydia trachomatis. Br J Vener Dis (1980) 1.85
Localization of three human polypeptide GalNAc-transferases in HeLa cells suggests initiation of O-linked glycosylation throughout the Golgi apparatus. J Cell Sci (1998) 1.84
Regulation of MHC class I transport by the molecular chaperone, calnexin (p88, IP90). Science (1994) 1.79
Empty and peptide-containing conformers of class I major histocompatibility complex molecules expressed in Drosophila melanogaster cells. Proc Natl Acad Sci U S A (1992) 1.79
A role for acidic residues in di-leucine motif-based targeting to the endocytic pathway. J Biol Chem (1995) 1.78
Occurrence of Ia antigens on tissues on non-lymphoid origin. Nature (1978) 1.76
Interleukin (IL)-1 receptor-associated kinase (IRAK) requirement for optimal induction of multiple IL-1 signaling pathways and IL-6 production. J Exp Med (1998) 1.75
The complete nucleotide sequence of the I-E alpha d immune response gene. Nucleic Acids Res (1983) 1.75
Isolation and identification of a cDNA clone corresponding to an HLA-DR antigen beta chain. Proc Natl Acad Sci U S A (1982) 1.75
Peptide length and sequence specificity of the mouse TAP1/TAP2 translocator. J Exp Med (1994) 1.73
Proteasomes are regulated by interferon gamma: implications for antigen processing. Proc Natl Acad Sci U S A (1992) 1.73
Radioimmunoassay of 2 -microglobulin in human biological fluids. Scand J Clin Lab Invest (1971) 1.71
Requirements for peptide-induced T cell receptor downregulation on naive CD8+ T cells. J Exp Med (1997) 1.70
Alphabeta T cell receptor interactions with syngeneic and allogeneic ligands: affinity measurements and crystallization. Proc Natl Acad Sci U S A (1997) 1.67
Crystal structures of two I-Ad-peptide complexes reveal that high affinity can be achieved without large anchor residues. Immunity (1998) 1.67
In vitro peptide binding to soluble empty class I major histocompatibility complex molecules isolated from transfected Drosophila melanogaster cells. J Biol Chem (1992) 1.66
Sequence of gene and cDNA encoding murine major histocompatibility complex class II gene A beta 2. J Biol Chem (1985) 1.66
Interaction of MHC class I molecules with the transporter associated with antigen processing. Science (1994) 1.65
Evolutionary relationship between immunoglobulins and transplantation antigens. Proc Natl Acad Sci U S A (1975) 1.62
Characterization of an HLA DR beta pseudogene. Proc Natl Acad Sci U S A (1985) 1.62
In vitro uptake of vitamin A from the retinol-binding plasma protein to mucosal epithelial cells from the monkey's small intestine. J Biol Chem (1976) 1.62
Immunodominance analysis of CTL responses to influenza PR8 virus reveals two new dominant and subdominant Kb-restricted epitopes. J Immunol (1996) 1.61
Intra- and Extracellular Localization of Lignin Peroxidase during the Degradation of Solid Wood and Wood Fragments by Phanerochaete chrysosporium by Using Transmission Electron Microscopy and Immuno-Gold Labeling. Appl Environ Microbiol (1989) 1.60