Published in Vaccine on January 12, 2011
Age-dependent dysregulation of innate immunity. Nat Rev Immunol (2013) 2.44
Controlled human infection and rechallenge with Streptococcus pneumoniae reveals the protective efficacy of carriage in healthy adults. Am J Respir Crit Care Med (2013) 1.84
Impaired neutrophil extracellular trap formation: a novel defect in the innate immune system of aged individuals. Aging Cell (2014) 0.95
Phagocyte dysfunction, tissue aging and degeneration. Ageing Res Rev (2013) 0.91
Serum IgM antibodies contribute to high levels of opsonophagocytic activities in toddlers immunized with a single dose of the 9-valent pneumococcal conjugate vaccine. Clin Vaccine Immunol (2012) 0.88
Persistence of functional antibodies to group B streptococcal capsular polysaccharides following immunization with glycoconjugate vaccines. Vaccine (2012) 0.86
Innate immune responses in the ageing lung. Clin Exp Immunol (2016) 0.82
Association of serotype-specific antibody concentrations and functional antibody titers with subsequent pneumococcal carriage in toddlers immunized with a 9-valent pneumococcal conjugate vaccine. Clin Vaccine Immunol (2011) 0.82
Theory and strategy for Pneumococcal vaccines in the elderly. Hum Vaccin Immunother (2016) 0.80
Immunosenescence, aging, and systemic lupus erythematous. Autoimmune Dis (2013) 0.80
Enhanced inflammation in aged mice following infection with Streptococcus pneumoniae is associated with decreased IL-10 and augmented chemokine production. Am J Physiol Lung Cell Mol Physiol (2015) 0.79
[Severe pneumococcal infections in the elderly - preventable by vaccination]. Z Gerontol Geriatr (2013) 0.79
Aging Related Atg5 Defect Impairs Neutrophil Extracellular Traps Formation. Immunology (2017) 0.78
Avidity of antibodies against infecting pneumococcal serotypes increases with age and severity of disease. Clin Vaccine Immunol (2014) 0.77
Immunological aspects of age-related diseases. World J Biol Chem (2017) 0.77
Effects of life events and stress on neutrophil functions in elderly men. Immun Ageing (2012) 0.76
Poor Correlation between Pneumococcal IgG and IgM Titers and Opsonophagocytic Activity in Vaccinated Patients with Multiple Myeloma and Waldenstrom's Macroglobulinemia. Clin Vaccine Immunol (2016) 0.75
Ficolin-2 inhibitors are present in sera after prolonged storage at -80 °C. PeerJ (2016) 0.75
The Alpha-Tocopherol Form of Vitamin E Boosts Elastase Activity of Human PMNs and Their Ability to Kill Streptococcus pneumoniae. Front Cell Infect Microbiol (2017) 0.75
Homeostatic Migration and Distribution of Innate Immune Cells in Primary and Secondary Lymphoid Organs with Aging. Clin Exp Immunol (2016) 0.75
Inflammaging and the Lung. Clin Geriatr Med (2017) 0.75
Long-term outcome associated with early repolarization on electrocardiography. N Engl J Med (2009) 4.53
Dietary intervention in infancy and later signs of beta-cell autoimmunity. N Engl J Med (2010) 4.16
Home-measured blood pressure is a stronger predictor of cardiovascular risk than office blood pressure: the Finn-Home study. Hypertension (2010) 3.82
Serum vitamin D and subsequent occurrence of type 2 diabetes. Epidemiology (2008) 3.80
Membranoproliferative glomerulonephritis type II (dense deposit disease): an update. J Am Soc Nephrol (2005) 3.57
Flavonoid intake and risk of chronic diseases. Am J Clin Nutr (2002) 3.57
Enzyme-linked immunosorbent assay for quantitation of human antibodies to pneumococcal polysaccharides. Clin Diagn Lab Immunol (2003) 3.27
Consumption of sweetened beverages and intakes of fructose and glucose predict type 2 diabetes occurrence. J Nutr (2007) 3.16
Serum 25-hydroxyvitamin D concentration and subsequent risk of type 2 diabetes. Diabetes Care (2007) 3.10
New approaches to the treatment of dense deposit disease. J Am Soc Nephrol (2007) 3.02
Incidence of end-stage renal disease in patients with type 1 diabetes. JAMA (2005) 3.01
Mutations in factor H reduce binding affinity to C3b and heparin and surface attachment to endothelial cells in hemolytic uremic syndrome. J Clin Invest (2003) 2.96
Serological criteria for evaluation and licensure of new pneumococcal conjugate vaccine formulations for use in infants. Vaccine (2003) 2.87
The prevalence of celiac disease in Europe: results of a centralized, international mass screening project. Ann Med (2010) 2.84
The fundamental link between pneumococcal carriage and disease. Expert Rev Vaccines (2012) 2.79
Whole-grain and fiber intake and the incidence of type 2 diabetes. Am J Clin Nutr (2003) 2.62
Dietary antioxidant intake and risk of type 2 diabetes. Diabetes Care (2004) 2.48
Incidence of schizophrenia in a nationwide cohort of patients with type 1 diabetes mellitus. Arch Gen Psychiatry (2007) 2.45
Early repolarization: electrocardiographic phenotypes associated with favorable long-term outcome. Circulation (2011) 2.38
Antibody response to 7-valent conjugated pneumococcal vaccine in patients with chronic lymphocytic leukaemia. Vaccine (2007) 2.07
Complement inhibitor factor H binding to Lyme disease spirochetes is mediated by inducible expression of multiple plasmid-encoded outer surface protein E paralogs. J Immunol (2002) 2.06
Vitamin D status and the risk of cardiovascular disease death. Am J Epidemiol (2009) 2.06
Y402H polymorphism of complement factor H affects binding affinity to C-reactive protein. J Immunol (2007) 2.00
Streptococcus pneumoniae evades complement attack and opsonophagocytosis by expressing the pspC locus-encoded Hic protein that binds to short consensus repeats 8-11 of factor H. J Immunol (2002) 1.87
Quantitative and qualitative anamnestic immune responses to pneumococcal conjugate vaccine in HIV-infected and HIV-uninfected children 5 years after vaccination. J Infect Dis (2009) 1.82
Dietary patterns and the incidence of type 2 diabetes. Am J Epidemiol (2005) 1.81
Tumor necrosis factor alpha enhances influenza A virus-induced expression of antiviral cytokines by activating RIG-I gene expression. J Virol (2006) 1.75
Structure of complement factor H carboxyl-terminus reveals molecular basis of atypical haemolytic uremic syndrome. EMBO J (2006) 1.72
QRS-T angle as a predictor of sudden cardiac death in a middle-aged general population. Europace (2011) 1.68
Association between complement factor H and proteoglycans in early human coronary atherosclerotic lesions: implications for local regulation of complement activation. Arterioscler Thromb Vasc Biol (2003) 1.68
Cardiovascular risk factors and low-back pain in a long-term follow-up of industrial employees. Scand J Work Environ Health (2006) 1.68
Predictive value of electrocardiographic QT interval and T-wave morphology parameters for all-cause and cardiovascular mortality in a general population sample. Heart Rhythm (2009) 1.68
IFN-alpha enhances TLR3-mediated antiviral cytokine expression in human endothelial and epithelial cells by up-regulating TLR3 expression. J Immunol (2005) 1.67
Prediction of type 1 diabetes in the general population. Diabetes Care (2010) 1.66
Immunogenicity and reactogenicity of 23-valent pneumococcal polysaccharide vaccine among pregnant Filipino women and placental transfer of antibodies. Vaccine (2007) 1.63
Metabolic syndrome among persons with schizophrenia and other psychotic disorders in a general population survey. J Clin Psychiatry (2007) 1.61
Dual interaction of factor H with C3d and glycosaminoglycans in host-nonhost discrimination by complement. Proc Natl Acad Sci U S A (2011) 1.58
Optimal schedule for home blood pressure measurement based on prognostic data: the Finn-Home Study. Hypertension (2011) 1.57
Complement resistance mechanisms of streptococci. Mol Immunol (2003) 1.56
Neisserial lipooligosaccharide is a target for complement component C4b. Inner core phosphoethanolamine residues define C4b linkage specificity. J Biol Chem (2003) 1.55
A nationwide survey of mortality in acromegaly. J Clin Endocrinol Metab (2005) 1.51
Increasing resources effected equity in access to revascularizations for patients with diabetes. Scand Cardiovasc J (2010) 1.45
Coronary heart disease: from a disease of middle-aged men in the late 1970s to a disease of elderly women in the 2000s. Eur Heart J (2005) 1.44
Prevalence and determinants of isolated clinic hypertension in the Finnish population: the Finn-HOME study. J Hypertens (2006) 1.43
Complement regulator-acquiring surface protein 1 imparts resistance to human serum in Borrelia burgdorferi. J Immunol (2005) 1.42
Binding of complement factor H to endothelial cells is mediated by the carboxy-terminal glycosaminoglycan binding site. Am J Pathol (2005) 1.40
Effect of HIV infection status and anti-retroviral treatment on quantitative and qualitative antibody responses to pneumococcal conjugate vaccine in infants. J Infect Dis (2010) 1.39
Polychlorinated biphenyls in prospectively collected serum and Parkinson's disease risk. Mov Disord (2012) 1.38
Obesity history as a predictor of walking limitation at old age. Obesity (Silver Spring) (2007) 1.38
Multilaboratory evaluation of a viability assay for measurement of opsonophagocytic antibodies specific to the capsular polysaccharides of Streptococcus pneumoniae. Clin Diagn Lab Immunol (2003) 1.38
Binding of the complement inhibitor C4bp to serogroup B Neisseria meningitidis. J Immunol (2005) 1.38
Yersinia enterocolitica serum resistance proteins YadA and ail bind the complement regulator C4b-binding protein. PLoS Pathog (2008) 1.36
Streptococcus pneumoniae capsular serotype 19F is more resistant to C3 deposition and less sensitive to opsonophagocytosis than serotype 6B. Infect Immun (2008) 1.33
Complement C3b/C3d and cell surface polyanions are recognized by overlapping binding sites on the most carboxyl-terminal domain of complement factor H. J Immunol (2002) 1.32
Intraventricular conduction delay in a standard 12-lead electrocardiogram as a predictor of mortality in the general population. Circ Arrhythm Electrophysiol (2011) 1.31
Quantitative and qualitative antibody response to pneumococcal conjugate vaccine among African human immunodeficiency virus-infected and uninfected children. Pediatr Infect Dis J (2005) 1.31
Evaluation of pneumococcal polysaccharide immunoassays using a 22F adsorption step with serum samples from infants vaccinated with conjugate vaccines. Clin Vaccine Immunol (2009) 1.25
Effects of ageing and gender on naturally acquired antibodies to pneumococcal capsular polysaccharides and virulence-associated proteins. Clin Vaccine Immunol (2008) 1.24
Binding of the long pentraxin PTX3 to factor H: interacting domains and function in the regulation of complement activation. J Immunol (2008) 1.23
Kinetics and avidity of antibodies evoked by heptavalent pneumococcal conjugate vaccines PncCRM and PncOMPC in the Finnish Otitis Media Vaccine Trial. Infect Immun (2005) 1.21
Regulation of complement activation at the C3-level by serum resistant leptospires. Microb Pathog (2005) 1.21
Long-term mortality in nationwide cohorts of childhood-onset type 1 diabetes in Japan and Finland. Diabetes Care (2003) 1.21
Lysine-dependent multipoint binding of the Borrelia burgdorferi virulence factor outer surface protein E to the C terminus of factor H. J Immunol (2004) 1.20
Clinical isolates of Streptococcus pneumoniae bind the complement inhibitor C4b-binding protein in a PspC allele-dependent fashion. J Immunol (2009) 1.18
Altered age-related blood pressure pattern in type 1 diabetes. Circulation (2004) 1.15
NPAS2 and PER2 are linked to risk factors of the metabolic syndrome. J Circadian Rhythms (2009) 1.15
Crosstalk between Hsp70 molecular chaperone, lysosomes and proteasomes in autophagy-mediated proteolysis in human retinal pigment epithelial cells. J Cell Mol Med (2008) 1.14
Seasonal changes in mood and behavior are linked to metabolic syndrome. PLoS One (2008) 1.11
Low metacarpal index predicts hip fracture: a prospective population study of 3,561 subjects with 15 years of follow-up. Acta Orthop (2006) 1.11
Complement activation associates with saccular cerebral artery aneurysm wall degeneration and rupture. Neurosurgery (2006) 1.11
Comparison of surface recognition and C3b binding properties of mouse and human complement factor H. Mol Immunol (2005) 1.10
Characterization of complement factor H binding to Yersinia enterocolitica serotype O:3. Infect Immun (2008) 1.10
The relative importance of modifiable potential risk factors of type 2 diabetes: a meta-analysis of two cohorts. Eur J Epidemiol (2009) 1.10
A nationwide population-based survey on visual acuity, near vision, and self-reported visual function in the adult population in Finland. Ophthalmology (2005) 1.09
Depression and C-reactive protein: population-based Health 2000 Study. Psychosom Med (2009) 1.08
High prevalence of four long QT syndrome founder mutations in the Finnish population. Ann Med (2009) 1.08
Specificities and opsonophagocytic activities of antibodies to pneumococcal capsular polysaccharides in sera of unimmunized young children. Clin Diagn Lab Immunol (2002) 1.08
Yin and Yang: complement activation and regulation in Alzheimer's disease. Prog Neurobiol (2003) 1.08
Complement inhibitor membrane cofactor protein (MCP; CD46) is constitutively shed from cancer cell membranes in vesicles and converted by a metalloproteinase to a functionally active soluble form. Eur J Immunol (2004) 1.07
Antibodies to periodontal pathogens and stroke risk. Stroke (2004) 1.07
Frequency of systemic vascular diseases in patients with primary open-angle glaucoma and exfoliation glaucoma. Acta Ophthalmol (2008) 1.07
Association between body weight and periodontal infection. J Clin Periodontol (2008) 1.06
Widening socioeconomic mortality disparity among diabetic people in Finland. Eur J Public Health (2003) 1.06
Protection by natural human immunoglobulin M antibody to meningococcal serogroup B capsular polysaccharide in the infant rat protection assay is independent of complement-mediated bacterial lysis. Infect Immun (2005) 1.06
Immunogenicity and effectiveness of Haemophilus influenzae type b conjugate vaccine in HIV infected and uninfected African children. Vaccine (2005) 1.06
Long term effects of vaccination of patients deficient in a late complement component with a tetravalent meningococcal polysaccharide vaccine. Vaccine (2003) 1.05
Interaction of pneumococcal histidine triad proteins with human complement. Infect Immun (2010) 1.05
The capsular serotype of Streptococcus pneumoniae is more important than the genetic background for resistance to complement. Infect Immun (2010) 1.05