Perifosine and CCI 779 co-operate to induce cell death and decrease proliferation in PTEN-intact and PTEN-deficient PDGF-driven murine glioblastoma.

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Published in PLoS One on January 18, 2011

Authors

Kenneth L Pitter1, Craig J Galbán, Stefanie Galbán, Omid Saeed Tehrani, Omid Saeed-Tehrani, Fei Li, Nikki Charles, Michelle S Bradbury, Oren J Becher, Thomas L Chenevert, Alnawaz Rehemtulla, Brian D Ross, Eric C Holland, Dolores Hambardzumyan

Author Affiliations

1: Department of Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America.

Associated clinical trials:

Temsirolimus and Perifosine in Treating Patients With Recurrent or Progressive Malignant Glioma | NCT01051557

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