Published in J Exp Med on January 31, 2011
Macrophage biology in development, homeostasis and disease. Nature (2013) 8.28
Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages. Nat Immunol (2012) 7.32
Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes. Immunity (2013) 5.47
The bone marrow niche for haematopoietic stem cells. Nature (2014) 5.06
Tissue-resident macrophages. Nat Immunol (2013) 4.09
Dendritic cell and macrophage heterogeneity in vivo. Immunity (2011) 3.41
Crosstalk between muscularis macrophages and enteric neurons regulates gastrointestinal motility. Cell (2014) 3.00
Myeloproliferative neoplasia remodels the endosteal bone marrow niche into a self-reinforcing leukemic niche. Cell Stem Cell (2013) 2.46
The bone marrow stem cell niche grows up: mesenchymal stem cells and macrophages move in. J Exp Med (2011) 2.36
Multipotent mesenchymal stromal cells and the innate immune system. Nat Rev Immunol (2012) 2.36
CD169⁺ macrophages provide a niche promoting erythropoiesis under homeostasis and stress. Nat Med (2013) 2.26
Rhythmic modulation of the hematopoietic niche through neutrophil clearance. Cell (2013) 2.19
The bone marrow at the crossroads of blood and immunity. Nat Rev Immunol (2011) 2.07
Hematopoietic stem cell niche maintenance during homeostasis and regeneration. Nat Med (2014) 2.05
Differential stem- and progenitor-cell trafficking by prostaglandin E2. Nature (2013) 1.99
Studying the mononuclear phagocyte system in the molecular age. Nat Rev Immunol (2011) 1.93
Neutrophil ageing is regulated by the microbiome. Nature (2015) 1.91
A family business: stem cell progeny join the niche to regulate homeostasis. Nat Rev Mol Cell Biol (2012) 1.91
Macrophages support pathological erythropoiesis in polycythemia vera and β-thalassemia. Nat Med (2013) 1.89
The canonical Wnt pathway shapes niches supportive of hematopoietic stem/progenitor cells. Blood (2011) 1.89
Acute myeloid leukemia creates an arginase-dependent immunosuppressive microenvironment. Blood (2013) 1.79
The hematopoietic stem cell niche--home for friend and foe? Cytometry B Clin Cytom (2012) 1.70
Megakaryocytes regulate hematopoietic stem cell quiescence through CXCL4 secretion. Nat Med (2014) 1.68
Nice neighborhood: emerging concepts of the stem cell niche. Cell (2014) 1.63
Regulation of hematopoietic stem and progenitor cell mobilization by cholesterol efflux pathways. Cell Stem Cell (2012) 1.62
Macrophage heterogeneity in tissues: phenotypic diversity and functions. Immunol Rev (2014) 1.55
Transit-amplifying cells orchestrate stem cell activity and tissue regeneration. Cell (2014) 1.50
Diabetes Limits Stem Cell Mobilization Following G-CSF but Not Plerixafor. Diabetes (2015) 1.47
Mobilization of hematopoietic stem and progenitor cells using inhibitors of CXCR4 and VLA-4. Leukemia (2011) 1.44
Bone marrow adipocytes promote the regeneration of stem cells and haematopoiesis by secreting SCF. Nat Cell Biol (2017) 1.39
Macrophage Colony Stimulating Factor Derived from CD4+ T Cells Contributes to Control of a Blood-Borne Infection. PLoS Pathog (2016) 1.39
Leukemia cell mobilization with G-CSF plus plerixafor during busulfan-fludarabine conditioning for allogeneic stem cell transplantation. Bone Marrow Transplant (2015) 1.38
Monocytes-macrophages that express α-smooth muscle actin preserve primitive hematopoietic cells in the bone marrow. Nat Immunol (2012) 1.38
Identification of myeloid cell subsets in murine lungs using flow cytometry. Am J Respir Cell Mol Biol (2013) 1.37
Metchnikoff's policemen: macrophages in development, homeostasis and regeneration. Trends Mol Med (2011) 1.34
A matter of life and death: self-renewal in stem cells. EMBO Rep (2012) 1.30
Heme-mediated SPI-C induction promotes monocyte differentiation into iron-recycling macrophages. Cell (2014) 1.30
Osteoclasts promote the formation of hematopoietic stem cell niches in the bone marrow. J Exp Med (2012) 1.28
Chemotherapy-induced bone marrow nerve injury impairs hematopoietic regeneration. Nat Med (2013) 1.25
Disruption of SIRPα signaling in macrophages eliminates human acute myeloid leukemia stem cells in xenografts. J Exp Med (2012) 1.24
Making sense of hematopoietic stem cell niches. Blood (2015) 1.23
Normal and leukemic stem cell niches: insights and therapeutic opportunities. Cell Stem Cell (2015) 1.20
Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs. Nat Commun (2015) 1.20
Advances in understanding the leukaemia microenvironment. Br J Haematol (2014) 1.19
Osteal macrophages support physiologic skeletal remodeling and anabolic actions of parathyroid hormone in bone. Proc Natl Acad Sci U S A (2014) 1.18
Essential role of the IRF8-KLF4 transcription factor cascade in murine monocyte differentiation. Blood (2013) 1.16
Regulation of macrophage development and function in peripheral tissues. Nat Rev Immunol (2015) 1.16
Distinct roles for hepcidin and interleukin-6 in the recovery from anemia in mice injected with heat-killed Brucella abortus. Blood (2013) 1.15
Redox regulation of stem/progenitor cells and bone marrow niche. Free Radic Biol Med (2012) 1.15
Macrophages and mesenchymal stromal cells support survival and proliferation of multiple myeloma cells. Br J Haematol (2012) 1.12
Regulation of hematopoietic and leukemic stem cells by the immune system. Cell Death Differ (2014) 1.10
The bone marrow microenvironment as niche retreats for hematopoietic and leukemic stem cells. Adv Hematol (2013) 1.09
Advances in stem cell mobilization. Blood Rev (2014) 1.09
Hematopoietic stem cell injury induced by ionizing radiation. Antioxid Redox Signal (2014) 1.09
Reactive oxygen species in normal and tumor stem cells. Adv Cancer Res (2014) 1.06
Macrophages retain hematopoietic stem cells in the spleen via VCAM-1. J Exp Med (2015) 1.06
Extracellular matrix protein tenascin-C is required in the bone marrow microenvironment primed for hematopoietic regeneration. Blood (2012) 1.06
Prostaglandin E2 increases hematopoietic stem cell survival and accelerates hematopoietic recovery after radiation injury. Stem Cells (2013) 1.05
The role of the local environment and epigenetics in shaping macrophage identity and their effect on tissue homeostasis. Nat Immunol (2015) 1.03
The spatial and developmental relationships in the macrophage family. Arterioscler Thromb Vasc Biol (2011) 1.02
Concise review: Current concepts in bone marrow microenvironmental regulation of hematopoietic stem and progenitor cells. Stem Cells (2013) 1.02
Pten loss in the bone marrow leads to G-CSF-mediated HSC mobilization. J Exp Med (2013) 1.02
Sialoadhesin - a macrophage-restricted marker of immunoregulation and inflammation. Immunology (2013) 1.02
Macrophages mediate cardioprotective cellular postconditioning in acute myocardial infarction. J Clin Invest (2015) 1.00
Much More than M1 and M2 Macrophages, There are also CD169(+) and TCR(+) Macrophages. Front Immunol (2015) 0.99
A hostel for the hostile: the bone marrow niche in hematologic neoplasms. Haematologica (2015) 0.99
Norepinephrine reuptake inhibition promotes mobilization in mice: potential impact to rescue low stem cell yields. Blood (2012) 0.98
Many mechanisms mediating mobilization: an alliterative review. Curr Opin Hematol (2011) 0.98
Hardwiring Stem Cell Communication through Tissue Structure. Cell (2016) 0.97
Myeloma plasma cells alter the bone marrow microenvironment by stimulating the proliferation of mesenchymal stromal cells. Haematologica (2013) 0.97
Intercellular network structure and regulatory motifs in the human hematopoietic system. Mol Syst Biol (2014) 0.96
Niche heterogeneity in the bone marrow. Ann N Y Acad Sci (2016) 0.96
Proteomic cornerstones of hematopoietic stem cell differentiation: distinct signatures of multipotent progenitors and myeloid committed cells. Mol Cell Proteomics (2012) 0.96
Reactive oxygen species regulate hematopoietic stem cell self-renewal, migration and development, as well as their bone marrow microenvironment. Antioxid Redox Signal (2014) 0.96
Getting blood from bone: an emerging understanding of the role that osteoblasts play in regulating hematopoietic stem cells within their niche. Exp Hematol (2012) 0.95
Concise review: diabetes, the bone marrow niche, and impaired vascular regeneration. Stem Cells Transl Med (2014) 0.95
The hematopoietic stem cell niche in homeostasis and disease. Blood (2015) 0.95
An isolated cryptic peptide influences osteogenesis and bone remodeling in an adult mammalian model of digit amputation. Tissue Eng Part A (2011) 0.94
Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal. Nat Cell Biol (2016) 0.94
Hypoxia and metabolic properties of hematopoietic stem cells. Antioxid Redox Signal (2013) 0.94
From proliferation to proliferation: monocyte lineage comes full circle. Semin Immunopathol (2014) 0.93
Age-associated changes in the ecological niche: implications for mesenchymal stem cell aging. Stem Cell Res Ther (2013) 0.93
B-lymphopoiesis is stopped by mobilizing doses of G-CSF and is rescued by overexpression of the anti-apoptotic protein Bcl2. Haematologica (2012) 0.93
Haematopoietic stem cell niches: new insights inspire new questions. EMBO J (2013) 0.93
Stem cells supporting other stem cells. Front Genet (2013) 0.92
Cancer stem cells and tumor-associated macrophages: a roadmap for multitargeting strategies. Oncogene (2015) 0.92
GRK6 deficiency in mice causes autoimmune disease due to impaired apoptotic cell clearance. Nat Commun (2013) 0.92
Macrophages: gatekeepers of tissue integrity. Cancer Immunol Res (2013) 0.91
The stem cell niche: tissue physiology at a single cell level. J Clin Invest (2012) 0.90
Circadian rhythms in leukocyte trafficking. Semin Immunopathol (2014) 0.90
Fak depletion in both hematopoietic and nonhematopoietic niche cells leads to hematopoietic stem cell expansion. Exp Hematol (2011) 0.90
Expansion of bone marrow neutrophils following G-CSF administration in mice results in osteolineage cell apoptosis and mobilization of hematopoietic stem and progenitor cells. Leukemia (2012) 0.90
CLEC-2 in megakaryocytes is critical for maintenance of hematopoietic stem cells in the bone marrow. J Exp Med (2015) 0.89
CD200 positive human mesenchymal stem cells suppress TNF-alpha secretion from CD200 receptor positive macrophage-like cells. PLoS One (2012) 0.89
Multiple myeloma cells recruit tumor-supportive macrophages through the CXCR4/CXCL12 axis and promote their polarization toward the M2 phenotype. Oncotarget (2014) 0.89
Heme oxygenase-1 deficiency alters erythroblastic island formation, steady-state erythropoiesis and red blood cell lifespan in mice. Haematologica (2015) 0.89
Macrophage-Lineage Cells Negatively Regulate the Hematopoietic Stem Cell Pool in Response to Interferon Gamma at Steady State and During Infection. Stem Cells (2015) 0.88
Recent progress toward understanding the physiological function of bone marrow mesenchymal stem cells. Immunology (2012) 0.87
Consequences of irradiation on bone and marrow phenotypes, and its relation to disruption of hematopoietic precursors. Bone (2014) 0.87
Monocyte and macrophage heterogeneity. Nat Rev Immunol (2005) 24.36
SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell (2005) 24.00
Mesenchymal and haematopoietic stem cells form a unique bone marrow niche. Nature (2010) 15.28
Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion. Mol Cell Biol (2000) 14.74
In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens. Immunity (2002) 14.57
Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications. J Immunol Methods (1994) 13.53
Maintenance of the hematopoietic stem cell pool by CXCL12-CXCR4 chemokine signaling in bone marrow stromal cell niches. Immunity (2006) 11.28
Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses. J Clin Invest (1996) 7.97
Flk-2 is a marker in hematopoietic stem cell differentiation: a simple method to isolate long-term stem cells. Proc Natl Acad Sci U S A (2001) 7.58
Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow. Cell (2006) 7.23
Bone-marrow haematopoietic-stem-cell niches. Nat Rev Immunol (2006) 7.20
Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche. Nature (2008) 6.61
Haematopoietic stem cell release is regulated by circadian oscillations. Nature (2008) 6.50
Colony-stimulating factors in inflammation and autoimmunity. Nat Rev Immunol (2008) 5.86
Functional macrophage cell lines transformed by Abelson leukemia virus. Cell (1978) 5.76
A Cre-inducible diphtheria toxin receptor mediates cell lineage ablation after toxin administration. Nat Methods (2005) 5.59
Neural stem and progenitor cells in nestin-GFP transgenic mice. J Comp Neurol (2004) 5.22
The essential functions of adipo-osteogenic progenitors as the hematopoietic stem and progenitor cell niche. Immunity (2010) 4.13
Characterization of tumor necrosis factor-deficient mice. Proc Natl Acad Sci U S A (1997) 4.10
G-CSF potently inhibits osteoblast activity and CXCL12 mRNA expression in the bone marrow. Blood (2005) 3.76
Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs. Blood (2010) 3.26
Lack of evidence that hematopoietic stem cells depend on N-cadherin-mediated adhesion to osteoblasts for their maintenance. Cell Stem Cell (2007) 2.96
Conditional macrophage ablation in transgenic mice expressing a Fas-based suicide gene. J Leukoc Biol (2004) 2.74
Osteoblasts support B-lymphocyte commitment and differentiation from hematopoietic stem cells. Blood (2007) 2.65
Mosaic removal of hedgehog signaling in the adult SVZ reveals that the residual wild-type stem cells have a limited capacity for self-renewal. J Neurosci (2007) 2.56
Conditional macrophage ablation demonstrates that resident macrophages initiate acute peritoneal inflammation. J Immunol (2005) 2.50
Osteal tissue macrophages are intercalated throughout human and mouse bone lining tissues and regulate osteoblast function in vitro and in vivo. J Immunol (2008) 2.39
The murine inhibitory receptor mSiglec-E is expressed broadly on cells of the innate immune system whereas mSiglec-F is restricted to eosinophils. Eur J Immunol (2004) 2.38
Critical role of macrophages in the marginal zone in the suppression of immune responses to apoptotic cell-associated antigens. J Clin Invest (2007) 2.34
Targeted disruption of the beta2 adrenergic receptor gene. J Biol Chem (1999) 2.28
Targeted disruption of the beta 3-adrenergic receptor gene. J Biol Chem (1995) 2.27
Endothelial selectins and vascular cell adhesion molecule-1 promote hematopoietic progenitor homing to bone marrow. Proc Natl Acad Sci U S A (1998) 2.06
Properties and distribution of a lectin-like hemagglutinin differentially expressed by murine stromal tissue macrophages. J Exp Med (1986) 1.96
Expression of the G-CSF receptor in monocytic cells is sufficient to mediate hematopoietic progenitor mobilization by G-CSF in mice. J Exp Med (2011) 1.96
Improving stem cell mobilization strategies: future directions. Bone Marrow Transplant (2009) 1.71
Cooperation of beta(2)- and beta(3)-adrenergic receptors in hematopoietic progenitor cell mobilization. Ann N Y Acad Sci (2010) 1.70
Expression of the G-CSF receptor on hematopoietic progenitor cells is not required for their mobilization by G-CSF. Blood (2000) 1.66
Mobilized hematopoietic stem cell yield depends on species-specific circadian timing. Cell Stem Cell (2008) 1.49
Hematopoietic stem cell trafficking: regulated adhesion and attraction to bone marrow microenvironment. Ann N Y Acad Sci (2007) 1.44
Expression and induction in vitro of macrophage differentiation antigens on murine cell lines. J Immunol (1983) 1.29
Conditioned medium from mouse sarcoma 180 cells contains vascular endothelial growth factor. Growth Factors (1990) 1.28
Maintenance of hemopoietic stem cells and production of differentiated progeny in allogeneic and semiallogeneic bone marrow chimeras in vitro. J Exp Med (1977) 1.14
The antigen recognized by MOMA-I is sialoadhesin. Immunol Lett (2006) 0.98
The integrin alphaMbeta2 anchors hematopoietic progenitors in the bone marrow during enforced mobilization. Blood (2004) 0.92
Changes in murine bone marrow macrophages and erythroid burst-forming cells following the intravenous injection of liposome-encapsulated dichloromethylene diphosphonate (Cl2MDP). Eur J Haematol (2001) 0.89
Mesenchymal and haematopoietic stem cells form a unique bone marrow niche. Nature (2010) 15.28
Development of monocytes, macrophages, and dendritic cells. Science (2010) 12.86
Fate mapping analysis reveals that adult microglia derive from primitive macrophages. Science (2010) 12.15
Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques. J Clin Invest (2007) 9.09
Local macrophage proliferation, rather than recruitment from the blood, is a signature of TH2 inflammation. Science (2011) 8.53
Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis. J Exp Med (2007) 7.87
Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages. Nat Immunol (2012) 7.32
Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow. Cell (2006) 7.23
Identification of a factor that links apoptotic cells to phagocytes. Nature (2002) 6.76
Haematopoietic stem cell release is regulated by circadian oscillations. Nature (2008) 6.50
Autonomic nerve development contributes to prostate cancer progression. Science (2013) 6.11
Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice. Science (2004) 6.07
Origin of the lamina propria dendritic cell network. Immunity (2009) 5.95
Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes. Immunity (2013) 5.47
Langerhans cells arise from monocytes in vivo. Nat Immunol (2006) 5.46
CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells. Cell (2009) 5.30
CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis. Cell (2009) 5.22
Anti-PlGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vessels. Cell (2007) 5.09
Adenovirus serotype 5 hexon mediates liver gene transfer. Cell (2008) 5.00
Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cells. Nature (2007) 4.88
The receptor tyrosine kinase Flt3 is required for dendritic cell development in peripheral lymphoid tissues. Nat Immunol (2008) 4.86
The origin and development of nonlymphoid tissue CD103+ DCs. J Exp Med (2009) 4.79
The meaning, the sense and the significance: translating the science of mesenchymal stem cells into medicine. Nat Med (2013) 4.32
MHC class II-dependent basophil-CD4+ T cell interactions promote T(H)2 cytokine-dependent immunity. Nat Immunol (2009) 4.28
Deciphering the transcriptional network of the dendritic cell lineage. Nat Immunol (2012) 4.17
Local proliferation dominates lesional macrophage accumulation in atherosclerosis. Nat Med (2013) 4.14
Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C-dependent buffering mechanism. Nat Med (2009) 4.07
B cell-driven lymphangiogenesis in inflamed lymph nodes enhances dendritic cell mobilization. Immunity (2006) 4.04
Dendritic cell-induced memory T cell activation in nonlymphoid tissues. Science (2008) 3.97
Bone marrow mesenchymal stem and progenitor cells induce monocyte emigration in response to circulating toll-like receptor ligands. Immunity (2011) 3.88
Flt3 ligand regulates dendritic cell development from Flt3+ lymphoid and myeloid-committed progenitors to Flt3+ dendritic cells in vivo. J Exp Med (2003) 3.74
Blood-derived dermal langerin+ dendritic cells survey the skin in the steady state. J Exp Med (2007) 3.64
Immature monocytes acquire antigens from other cells in the bone marrow and present them to T cells after maturing in the periphery. J Exp Med (2006) 3.43
Microglia promote the death of developing Purkinje cells. Neuron (2004) 3.42
IL-33 amplifies the polarization of alternatively activated macrophages that contribute to airway inflammation. J Immunol (2009) 3.41
Dendritic cell and macrophage heterogeneity in vivo. Immunity (2011) 3.41
Alveolar macrophages have a protective antiinflammatory role during murine pneumococcal pneumonia. Am J Respir Crit Care Med (2002) 3.27
Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs. Blood (2010) 3.26
Hepatic recruitment of the inflammatory Gr1+ monocyte subset upon liver injury promotes hepatic fibrosis. Hepatology (2009) 3.20
Macrophage depletion inhibits experimental choroidal neovascularization. Invest Ophthalmol Vis Sci (2003) 3.17
Microbiota-dependent crosstalk between macrophages and ILC3 promotes intestinal homeostasis. Science (2014) 3.13
The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity. Cell Metab (2010) 3.11
Arteriolar niches maintain haematopoietic stem cell quiescence. Nature (2013) 3.07
Toll-like receptor-4 signaling and Kupffer cells play pivotal roles in the pathogenesis of non-alcoholic steatohepatitis. J Hepatol (2007) 3.06
Blood monocyte subsets differentially give rise to CD103+ and CD103- pulmonary dendritic cell populations. J Immunol (2008) 3.04
Characterization of the dust/smoke aerosol that settled east of the World Trade Center (WTC) in lower Manhattan after the collapse of the WTC 11 September 2001. Environ Health Perspect (2002) 2.93
Heterotypic interactions enabled by polarized neutrophil microdomains mediate thromboinflammatory injury. Nat Med (2009) 2.93
Macrophage depletion impairs wound healing and increases left ventricular remodeling after myocardial injury in mice. Am J Pathol (2007) 2.84
Lymph-migrating, tissue-derived dendritic cells are minor constituents within steady-state lymph nodes. J Exp Med (2008) 2.73
Primary role for adherent leukocytes in sickle cell vascular occlusion: a new paradigm. Proc Natl Acad Sci U S A (2002) 2.72
Hypoxia-induced pulmonary vascular remodeling requires recruitment of circulating mesenchymal precursors of a monocyte/macrophage lineage. Am J Pathol (2006) 2.70
Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac-derived macrophages. J Exp Med (2012) 2.69
Role of CCR8 and other chemokine pathways in the migration of monocyte-derived dendritic cells to lymph nodes. J Exp Med (2004) 2.68
Dendritic cells rapidly recruited into epithelial tissues via CCR6/CCL20 are responsible for CD8+ T cell crosspriming in vivo. Immunity (2006) 2.62
Notch2 receptor signaling controls functional differentiation of dendritic cells in the spleen and intestine. Immunity (2011) 2.61
Minimal differentiation of classical monocytes as they survey steady-state tissues and transport antigen to lymph nodes. Immunity (2013) 2.61
Excessive neutrophils and neutrophil extracellular traps contribute to acute lung injury of influenza pneumonitis. Am J Pathol (2011) 2.57
Identification of coagulation factor (F)X binding sites on the adenovirus serotype 5 hexon: effect of mutagenesis on FX interactions and gene transfer. Blood (2009) 2.55
Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis. Proc Natl Acad Sci U S A (2012) 2.54
Kupffer cells promote hepatic steatosis via interleukin-1beta-dependent suppression of peroxisome proliferator-activated receptor alpha activity. Hepatology (2010) 2.53
Enforced viral replication activates adaptive immunity and is essential for the control of a cytopathic virus. Nat Immunol (2011) 2.51
Dystroglycan is selectively cleaved at the parenchymal basement membrane at sites of leukocyte extravasation in experimental autoimmune encephalomyelitis. J Exp Med (2006) 2.51
Kupffer cell and interleukin-12-dependent loss of natural killer T cells in hepatosteatosis. Hepatology (2010) 2.48
Extramedullary hematopoiesis generates Ly-6C(high) monocytes that infiltrate atherosclerotic lesions. Circulation (2011) 2.45
Rapid induction of inflammatory lipid mediators by the inflammasome in vivo. Nature (2012) 2.41
On the pathogenic role of brain-sequestered alphabeta CD8+ T cells in experimental cerebral malaria. J Immunol (2002) 2.40
Plasmacytoid dendritic cells prime alloreactive T cells to mediate graft-versus-host disease as antigen-presenting cells. Blood (2009) 2.39
Suppressed monocyte recruitment drives macrophage removal from atherosclerotic plaques of Apoe-/- mice during disease regression. J Clin Invest (2011) 2.37
CD169-positive macrophages dominate antitumor immunity by crosspresenting dead cell-associated antigens. Immunity (2010) 2.37
CCR2 promotes hepatic fibrosis in mice. Hepatology (2009) 2.35
Role of macrophage targeting in the antitumor activity of trabectedin. Cancer Cell (2013) 2.35
Cell-specific gene expression in Langerhans cell histiocytosis lesions reveals a distinct profile compared with epidermal Langerhans cells. J Immunol (2010) 2.35
Critical role of macrophages in the marginal zone in the suppression of immune responses to apoptotic cell-associated antigens. J Clin Invest (2007) 2.34
Simultaneous targeting of toll- and nod-like receptors induces effective tumor-specific immune responses. Sci Transl Med (2012) 2.33
CD169⁺ macrophages provide a niche promoting erythropoiesis under homeostasis and stress. Nat Med (2013) 2.26