Published in Nat Rev Gastroenterol Hepatol on February 08, 2011
The clinical importance of emerging Campylobacter species. Nat Rev Gastroenterol Hepatol (2011) 2.12
Global Epidemiology of Campylobacter Infection. Clin Microbiol Rev (2015) 1.73
Intestinal microbiota shifts towards elevated commensal Escherichia coli loads abrogate colonization resistance against Campylobacter jejuni in mice. PLoS One (2012) 1.63
The role of the immune system in governing host-microbe interactions in the intestine. Nat Immunol (2013) 1.41
Immunopathogenesis of IBD: current state of the art. Nat Rev Gastroenterol Hepatol (2015) 1.34
Inflammatory monocytes regulate pathologic responses to commensals during acute gastrointestinal infection. Nat Med (2013) 1.30
Regulation of inflammasome activation. Immunol Rev (2015) 1.28
Effect of exclusive enteral nutrition on the microbiota of children with newly diagnosed Crohn's disease. Clin Transl Gastroenterol (2015) 1.18
Intestinal dysbiosis associated with systemic lupus erythematosus. MBio (2014) 1.14
Campylobacter concisus - A new player in intestinal disease. Front Cell Infect Microbiol (2012) 1.12
Microbial dysbiosis in pediatric patients with Crohn's disease. J Clin Microbiol (2012) 1.10
Crohn's and colitis in children and adolescents. World J Gastroenterol (2012) 1.10
Intraluminal containment of commensal outgrowth in the gut during infection-induced dysbiosis. Cell Host Microbe (2013) 1.08
Increase of faecal tryptic activity relates to changes in the intestinal microbiome: analysis of Crohn's disease with a multidisciplinary platform. PLoS One (2013) 0.99
Comparative (meta)genomic analysis and ecological profiling of human gut-specific bacteriophage φB124-14. PLoS One (2012) 0.96
Systems biology analysis of gene expression during in vivo Mycobacterium avium paratuberculosis enteric colonization reveals role for immune tolerance. PLoS One (2012) 0.95
Candida albicans primes TLR cytokine responses through a Dectin-1/Raf-1-mediated pathway. J Immunol (2013) 0.89
Seroprevalence of campylobacteriosis and relevant post-infectious sequelae. Eur J Clin Microbiol Infect Dis (2014) 0.89
Genetic dysbiosis: the role of microbial insults in chronic inflammatory diseases. J Oral Microbiol (2014) 0.86
The histopathological approach to inflammatory bowel disease: a practice guide. Virchows Arch (2014) 0.86
The role of autophagy in the intracellular survival of Campylobacter concisus. FEBS Open Bio (2014) 0.84
Accurate genome relative abundance estimation for closely related species in a metagenomic sample. BMC Bioinformatics (2014) 0.83
Comprehensive detection and discrimination of Campylobacter species by use of confocal micro-Raman spectroscopy and multilocus sequence typing. J Clin Microbiol (2012) 0.83
Circulating microparticles from Crohn's disease patients cause endothelial and vascular dysfunctions. PLoS One (2013) 0.81
Using phage display selected antibodies to dissect microbiomes for complete de novo genome sequencing of low abundance microbes. BMC Microbiol (2013) 0.81
Th17 responses and natural IgM antibodies are related to gut microbiota composition in systemic lupus erythematosus patients. Sci Rep (2016) 0.81
Interaction of Intestinal Microorganisms with the Human Host in the Framework of Autoimmune Diseases. Front Immunol (2015) 0.80
Environmental influences on the onset and clinical course of Crohn's disease-part 1: an overview of external risk factors. Gastroenterol Hepatol (N Y) (2013) 0.80
The microbiome and colorectal neoplasia: environmental modifiers of dysbiosis. Curr Gastroenterol Rep (2013) 0.79
Managing inflammatory bowel disease in adolescent patients. Adolesc Health Med Ther (2014) 0.79
Neuroimmunomodulation in the Gut: Focus on Inflammatory Bowel Disease. Mediators Inflamm (2016) 0.77
Culture- and quantitative IS900 real-time PCR-based analysis of the persistence of Mycobacterium avium subsp. paratuberculosis in a controlled dairy cow farm environment. Appl Environ Microbiol (2012) 0.77
Immunoregulatory function of PIR-A/B+ DCs in the inflammatory responses of dextran sodium sulfate-induced colitis. J Gastroenterol (2013) 0.77
Human colon-derived soluble factors modulate gut microbiota composition. Front Oncol (2015) 0.76
The role of autophagy in Crohn's disease. Cells (2012) 0.76
Biological pathways involved in the development of inflammatory bowel disease. Wien Klin Wochenschr (2014) 0.76
Unique β-Glucuronidase Locus in Gut Microbiomes of Crohn's Disease Patients and Unaffected First-Degree Relatives. PLoS One (2016) 0.76
Environmental influences on the onset and clinical course of Crohn's disease-part 2: infections and medication use. Gastroenterol Hepatol (N Y) (2013) 0.75
Carrageenan Gum and Adherent Invasive Escherichia coli in a Piglet Model of Inflammatory Bowel Disease: Impact on Intestinal Mucosa-associated Microbiota. Front Microbiol (2016) 0.75
Rapid change of fecal microbiome and disappearance of Clostridium difficile in a colonized infant after transition from breast milk to cow milk. Microbiome (2016) 0.75
Functional relationship between Campylobacter concisus and the stomach ecosystem in health and disease. ISME J (2013) 0.75
The intestinal microbiome, barrier function, and immune system in inflammatory bowel disease: a tripartite pathophysiological circuit with implications for new therapeutic directions. Therap Adv Gastroenterol (2016) 0.75
Starter Feeding Supplementation Alters Colonic Mucosal Bacterial Communities and Modulates Mucosal Immune Homeostasis in Newborn Lambs. Front Microbiol (2017) 0.75
Diet and microbiota in inflammatory bowel disease: The gut in disharmony. World J Gastroenterol (2017) 0.75
Control of lupus nephritis by changes of gut microbiota. Microbiome (2017) 0.75
A human gut microbial gene catalogue established by metagenomic sequencing. Nature (2010) 43.63
Autophagy fights disease through cellular self-digestion. Nature (2008) 33.83
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature (2001) 33.12
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature (2001) 28.24
A Toll-like receptor recognizes bacterial DNA. Nature (2000) 26.34
Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases. Proc Natl Acad Sci U S A (2007) 20.60
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet (2007) 19.08
Cryopyrin activates the inflammasome in response to toxins and ATP. Nature (2006) 18.74
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. Nat Genet (2006) 15.14
Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases. N Engl J Med (1997) 14.51
Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients. Proc Natl Acad Sci U S A (2008) 14.18
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility. Nat Genet (2007) 13.74
Reduced diversity of faecal microbiota in Crohn's disease revealed by a metagenomic approach. Gut (2005) 10.95
A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells. Nature (2008) 10.84
Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease. Nat Genet (2008) 9.52
Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome. Nat Genet (2001) 9.34
Human IRGM induces autophagy to eliminate intracellular mycobacteria. Science (2006) 9.17
TLR4 mutations are associated with endotoxin hyporesponsiveness in humans. Nat Genet (2000) 8.79
Mucosal flora in inflammatory bowel disease. Gastroenterology (2002) 8.42
How host-microbial interactions shape the nutrient environment of the mammalian intestine. Annu Rev Nutr (2002) 8.31
Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan. Science (2003) 7.49
Intracellular NOD-like receptors in host defense and disease. Immunity (2007) 6.48
Toll-like receptor 4 polymorphisms and atherogenesis. N Engl J Med (2002) 6.00
High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn's disease. Gastroenterology (2004) 5.94
Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry. Nat Immunol (2009) 5.83
Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease. Infect Immun (2000) 5.65
Spatial organization and composition of the mucosal flora in patients with inflammatory bowel disease. J Clin Microbiol (2005) 5.62
NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation. Nat Med (2009) 5.43
Reduction in diversity of the colonic mucosa associated bacterial microflora in patients with active inflammatory bowel disease. Gut (2004) 5.32
Alterations of the dominant faecal bacterial groups in patients with Crohn's disease of the colon. Gut (2003) 5.19
The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis. Immunity (2010) 5.12
Reduced Paneth cell alpha-defensins in ileal Crohn's disease. Proc Natl Acad Sci U S A (2005) 5.05
Effect of faecal stream diversion on recurrence of Crohn's disease in the neoterminal ileum. Lancet (1991) 5.02
Dysbiosis in inflammatory bowel disease. Gut (2004) 5.01
Enhanced Escherichia coli adherence and invasion in Crohn's disease and colon cancer. Gastroenterology (2004) 4.89
Low counts of Faecalibacterium prausnitzii in colitis microbiota. Inflamm Bowel Dis (2009) 4.72
Stimulation of the intracellular bacterial sensor NOD2 programs dendritic cells to promote interleukin-17 production in human memory T cells. Immunity (2007) 4.70
Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis. Cell Host Microbe (2010) 4.54
Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella. J Exp Med (2010) 4.52
NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal alpha-defensin expression. Gut (2004) 4.39
High-throughput diversity and functionality analysis of the gastrointestinal tract microbiota. Gut (2008) 4.10
Early lesions of recurrent Crohn's disease caused by infusion of intestinal contents in excluded ileum. Gastroenterology (1998) 4.08
Relevance of mutations in the TLR4 receptor in patients with gram-negative septic shock. Arch Intern Med (2002) 4.00
CARD15/NOD2 functions as an antibacterial factor in human intestinal epithelial cells. Gastroenterology (2003) 3.70
Host-mediated inflammation disrupts the intestinal microbiota and promotes the overgrowth of Enterobacteriaceae. Cell Host Microbe (2007) 3.28
Genetic analysis of innate immunity in Crohn's disease and ulcerative colitis identifies two susceptibility loci harboring CARD9 and IL18RAP. Am J Hum Genet (2008) 3.11
Differences between tissue-associated intestinal microfloras of patients with Crohn's disease and ulcerative colitis. J Clin Microbiol (2006) 3.02
Mucosal and invading bacteria in patients with inflammatory bowel disease compared with controls. Scand J Gastroenterol (2002) 3.00
Emergence of diverse Helicobacter species in the pathogenesis of gastric and enterohepatic diseases. Clin Microbiol Rev (2001) 2.97
Molecular analysis of the gut microbiota of identical twins with Crohn's disease. ISME J (2008) 2.96
Invasive ability of an Escherichia coli strain isolated from the ileal mucosa of a patient with Crohn's disease. Infect Immun (1999) 2.92
Mycobacterium avium subspecies paratuberculosis and Crohn's disease: a systematic review and meta-analysis. Lancet Infect Dis (2007) 2.85
Twin studies reveal specific imbalances in the mucosa-associated microbiota of patients with ileal Crohn's disease. Inflamm Bowel Dis (2009) 2.85
ATG16L1 and NOD2 interact in an autophagy-dependent antibacterial pathway implicated in Crohn's disease pathogenesis. Gastroenterology (2010) 2.83
Crohn's disease and the NOD2 gene: a role for paneth cells. Gastroenterology (2003) 2.72
Common variants in the NLRP3 region contribute to Crohn's disease susceptibility. Nat Genet (2008) 2.67
Crohn's disease-associated NOD2 variants share a signaling defect in response to lipopolysaccharide and peptidoglycan. Gastroenterology (2003) 2.64
Increased short- and long-term risk of inflammatory bowel disease after salmonella or campylobacter gastroenteritis. Gastroenterology (2009) 2.57
Immunocytochemical evidence of Listeria, Escherichia coli, and Streptococcus antigens in Crohn's disease. Gastroenterology (1995) 2.47
Specificities of the fecal microbiota in inflammatory bowel disease. Inflamm Bowel Dis (2006) 2.45
Commensal bacteria, traditional and opportunistic pathogens, dysbiosis and bacterial killing in inflammatory bowel diseases. Curr Opin Infect Dis (2009) 2.44
CEACAM6 acts as a receptor for adherent-invasive E. coli, supporting ileal mucosa colonization in Crohn disease. J Clin Invest (2007) 2.44
High prevalence of Escherichia coli belonging to the B2+D phylogenetic group in inflammatory bowel disease. Gut (2006) 2.43
Abnormal microbiota composition in the ileocolonic mucosa of Crohn's disease patients as revealed by polymerase chain reaction-denaturing gradient gel electrophoresis. Inflamm Bowel Dis (2006) 2.38
Autophagy gene variant IRGM -261T contributes to protection from tuberculosis caused by Mycobacterium tuberculosis but not by M. africanum strains. PLoS Pathog (2009) 2.35
Toll-like receptors--taking an evolutionary approach. Nat Rev Genet (2008) 2.31
Tumour necrosis factor alpha and interleukin 1beta in relapse of Crohn's disease. Lancet (1999) 2.29
Adherent invasive Escherichia coli strains from patients with Crohn's disease survive and replicate within macrophages without inducing host cell death. Infect Immun (2001) 2.28
Gut-associated bacterial microbiota in paediatric patients with inflammatory bowel disease. Gut (2006) 2.24
Double blind, placebo controlled trial of metronidazole in Crohn's disease. Gut (1991) 2.24
Crohn's disease-associated adherent-invasive E. coli are selectively favoured by impaired autophagy to replicate intracellularly. Cell Microbiol (2009) 2.23
The impact of the microbiota on the pathogenesis of IBD: lessons from mouse infection models. Nat Rev Microbiol (2010) 2.22
Chronic stimulation of Nod2 mediates tolerance to bacterial products. Proc Natl Acad Sci U S A (2007) 2.20
Adjunctive antibiotic therapy with rifaximin may help reduce Crohn's disease activity. Dig Dis Sci (2010) 2.18
Detection of Mycobacterium avium subspecies paratuberculosis from patients with Crohn's disease using nucleic acid-based techniques: a systematic review and meta-analysis. Inflamm Bowel Dis (2008) 2.12
Detection and isolation of Campylobacter species other than C. jejuni from children with Crohn's disease. J Clin Microbiol (2008) 2.06
Expression of Toll-like receptor 2 (TLR2), TLR4, and CD14 in biopsy samples of patients with inflammatory bowel diseases: upregulated expression of TLR2 in terminal ileum of patients with ulcerative colitis. J Histochem Cytochem (2007) 2.06
Association between a genomic polymorphism within the CD14 locus and septic shock susceptibility and mortality rate. Crit Care Med (2002) 1.97
Molecular diversity of Escherichia coli in the human gut: new ecological evidence supporting the role of adherent-invasive E. coli (AIEC) in Crohn's disease. Inflamm Bowel Dis (2009) 1.88
Association between Helicobacter pylori infection and inflammatory bowel disease: a meta-analysis and systematic review of the literature. Inflamm Bowel Dis (2010) 1.86
Dysbiosis of fecal microbiota in Crohn's disease patients as revealed by a custom phylogenetic microarray. Inflamm Bowel Dis (2010) 1.84
Nod2 regulates the host response towards microflora by modulating T cell function and epithelial permeability in mouse Peyer's patches. Gut (2009) 1.83
Association between a complex insertion/deletion polymorphism in NOD1 (CARD4) and susceptibility to inflammatory bowel disease. Hum Mol Genet (2005) 1.81
Epistasis between Toll-like receptor-9 polymorphisms and variants in NOD2 and IL23R modulates susceptibility to Crohn's disease. Am J Gastroenterol (2009) 1.80
The bacteriology of biopsies differs between newly diagnosed, untreated, Crohn's disease and ulcerative colitis patients. J Med Microbiol (2006) 1.79
Toll-like receptor-1, -2, and -6 polymorphisms influence disease extension in inflammatory bowel diseases. Inflamm Bowel Dis (2006) 1.79
Nod2-dependent Th2 polarization of antigen-specific immunity. J Immunol (2008) 1.78
Evaluation of Helicobacter species in inflammatory bowel disease. Aliment Pharmacol Ther (2003) 1.73
TUCAN (CARD8) genetic variants and inflammatory bowel disease. Gastroenterology (2006) 1.73
Highlighting new phylogenetic specificities of Crohn's disease microbiota. Inflamm Bowel Dis (2010) 1.70
TLR2, TLR4 and TLR9 polymorphisms and Crohn's disease in a New Zealand Caucasian cohort. J Gastroenterol Hepatol (2007) 1.70
The molecular basis of the host response to lipopolysaccharide. Nat Rev Microbiol (2010) 1.70
Campylobacter concisus and other Campylobacter species in children with newly diagnosed Crohn's disease. Inflamm Bowel Dis (2010) 1.69
NOD1 variation, immunoglobulin E and asthma. Hum Mol Genet (2005) 1.66
Imbalance in intestinal microflora constitution could be involved in the pathogenesis of inflammatory bowel disease. Int J Med Microbiol (2007) 1.65
Ribosomal DNA sequence analysis of mucosa-associated bacteria in Crohn's disease. Inflamm Bowel Dis (2004) 1.65
ATG16L1 and IL23R are associated with inflammatory bowel diseases but not with celiac disease in the Netherlands. Am J Gastroenterol (2007) 1.58
Active Crohn's disease and ulcerative colitis can be specifically diagnosed and monitored based on the biostructure of the fecal flora. Inflamm Bowel Dis (2008) 1.57
Host attachment, invasion, and stimulation of proinflammatory cytokines by Campylobacter concisus and other non-Campylobacter jejuni Campylobacter species. J Infect Dis (2010) 1.48
Prevalence of Campylobacter species in adult Crohn's disease and the preferential colonization sites of Campylobacter species in the human intestine. PLoS One (2011) 1.27
In vivo behavior of a Helicobacter pylori SS1 nixA mutant with reduced urease activity. Infect Immun (2002) 1.21
Microbial dysbiosis in pediatric patients with Crohn's disease. J Clin Microbiol (2012) 1.10
Comment to: Changes of faecal microflora in patients with Crohn's disease treated with an elemental diet and total parenteral nutrition. Dig Liver Dis (2012) 1.09
Inflammatory bowel disease therapies and gut function in a colitis mouse model. Biomed Res Int (2013) 1.00
Pathogenic potential of Campylobacter ureolyticus. Infect Immun (2011) 0.98
Immunoreactive proteins of Campylobacter concisus, an emergent intestinal pathogen. FEMS Immunol Med Microbiol (2011) 0.96
The secretome of Helicobacter trogontum. Helicobacter (2013) 0.93
The prevalence of the duodenal ulcer promoting gene (dupA) in Helicobacter pylori isolates varies by ethnic group and is not universally associated with disease development: a case-control study. Gut Pathog (2009) 0.92
Gastric epithelial cell CXC chemokine secretion following Helicobacter pylori infection in vitro. J Gastroenterol Hepatol (2004) 0.92
The role of TLR2, TLR4 and CD14 genetic polymorphisms in gastric carcinogenesis: a case-control study and meta-analysis. PLoS One (2013) 0.91
Comparative genomics of Campylobacter concisus isolates reveals genetic diversity and provides insights into disease association. BMC Genomics (2013) 0.90
Bacterial aetiological agents of intra-amniotic infections and preterm birth in pregnant women. Front Cell Infect Microbiol (2013) 0.90
How accurately can we detect Mycobacterium avium subsp. paratuberculosis infection? J Microbiol Methods (2011) 0.89
Sequencing and validation of the genome of a Campylobacter concisus reveals intra-species diversity. PLoS One (2011) 0.89
Is Helicobacter pylori a true microaerophile? Helicobacter (2006) 0.88
Draft genome sequences of Helicobacter pylori isolates from Malaysia, cultured from patients with functional dyspepsia and gastric cancer. J Bacteriol (2012) 0.88
Multiple Genome Sequences of Helicobacter pylori Strains of Diverse Disease and Antibiotic Resistance Backgrounds from Malaysia. Genome Announc (2013) 0.87
S100 calgranulin proteins S100A8, S100A9 and S100A12 are expressed in the inflamed gastric mucosa of Helicobacter pylori-infected children. Can J Gastroenterol (2008) 0.87
Helicobacter spp. other than Helicobacter pylori. Helicobacter (2010) 0.86
Protease-activated receptor-1 down-regulates the murine inflammatory and humoral response to Helicobacter pylori. Gastroenterology (2009) 0.85
Tools to covisualize and coanalyze proteomic data with genomes and transcriptomes: validation of genes and alternative mRNA splicing. J Proteome Res (2013) 0.85
Role of emerging Campylobacter species in inflammatory bowel diseases. Inflamm Bowel Dis (2014) 0.84
Role of Helicobacter species in Chinese patients with inflammatory bowel disease. J Clin Microbiol (2011) 0.83
The internal transcribed spacer region, a new tool for use in species differentiation and delineation of systematic relationships within the Campylobacter genus. Appl Environ Microbiol (2010) 0.82
Donor Recruitment for Fecal Microbiota Transplantation. Inflamm Bowel Dis (2015) 0.81
Phosphonate metabolism in Helicobacter pylori. Antonie Van Leeuwenhoek (2009) 0.81
PAR-1 polymorphisms and risk of Helicobacter pylori-related gastric cancer in a Chinese population. Anticancer Res (2012) 0.79
Campylobacter concisus and exotoxin 9 levels in paediatric patients with Crohn's disease and their association with the intestinal microbiota. J Med Microbiol (2013) 0.78
The pathogenic potential of Helicobacter pullorum: possible role for the type VI secretion system. Helicobacter (2012) 0.78
Characterization and application of a new monoclonal antibody with high specificity for Helicobacter hepaticus. Helicobacter (2009) 0.77
Interactions between gastric and enteric infections: clues to the pathogenesis of inflammatory bowel disease? N Z Med J (2011) 0.77
A comparison of glycan expression and adhesion of mouse-adapted strains and clinical isolates of Helicobacter pylori. FEMS Immunol Med Microbiol (2009) 0.76
Did transmission of Helicobacter pylori from humans cause a disease outbreak in a colony of Stripe-faced Dunnarts (Sminthopsis macroura)? Vet Res (2011) 0.76
Characterisation of Campylobacter jejuni genes potentially involved in phosphonate degradation. Gut Pathog (2009) 0.76
The NOD-like receptor signalling pathway in Helicobacter pylori infection and related gastric cancer: a case-control study and gene expression analyses. PLoS One (2015) 0.75
Genome Sequence of Campylobacter showae UNSWCD, Isolated from a Patient with Crohn's Disease. Genome Announc (2013) 0.75
Investigation of motility and biofilm formation by intestinal Campylobacter concisus strains. Gut Pathog (2012) 0.75
Functional relationship between Campylobacter concisus and the stomach ecosystem in health and disease. ISME J (2013) 0.75
Role of serum factors in epithelial cell responses to Helicobacter pylori infection in vitro. J Gastroenterol Hepatol (2005) 0.75
Do type VI secretion systems translocate more than proteins? Helicobacter (2013) 0.75