Published in ACS Nano on February 16, 2011
Use of metal oxide nanoparticle band gap to develop a predictive paradigm for oxidative stress and acute pulmonary inflammation. ACS Nano (2012) 2.35
Toxicity of nanomaterials. Chem Soc Rev (2011) 2.07
Implementation of alternative test strategies for the safety assessment of engineered nanomaterials. J Intern Med (2013) 1.74
Nanomaterial toxicity testing in the 21st century: use of a predictive toxicological approach and high-throughput screening. Acc Chem Res (2012) 1.56
Interactions of engineered nanomaterials in physiological media and implications for in vitro dosimetry. Nanotoxicology (2012) 1.54
An in vivo and in vitro toxicological characterisation of realistic nanoscale CeO₂ inhalation exposures. Nanotoxicology (2012) 1.43
Designed synthesis of CeO2 nanorods and nanowires for studying toxicological effects of high aspect ratio nanomaterials. ACS Nano (2012) 1.39
Microfluidic technologies for accelerating the clinical translation of nanoparticles. Nat Nanotechnol (2012) 1.39
Surface defects on plate-shaped silver nanoparticles contribute to its hazard potential in a fish gill cell line and zebrafish embryos. ACS Nano (2012) 1.32
An integrated approach for the in vitro dosimetry of engineered nanomaterials. Part Fibre Toxicol (2014) 1.21
A Safer Formulation Concept for Flame-Generated Engineered Nanomaterials. ACS Sustain Chem Eng (2013) 1.17
High content screening in zebrafish speeds up hazard ranking of transition metal oxide nanoparticles. ACS Nano (2011) 1.08
Large-scale assessment of the zebrafish embryo as a possible predictive model in toxicity testing. PLoS One (2011) 1.00
In vivo quantitative study of sized-dependent transport and toxicity of single silver nanoparticles using zebrafish embryos. Chem Res Toxicol (2012) 0.99
Integrating zebrafish toxicology and nanoscience for safer product development. Green Chem (2013) 0.98
Zebrafish: an in vivo model for nano EHS studies. Small (2012) 0.96
Automated phenotype recognition for zebrafish embryo based in vivo high throughput toxicity screening of engineered nano-materials. PLoS One (2012) 0.89
High content analysis provides mechanistic insights on the pathways of toxicity induced by amine-modified polystyrene nanoparticles. PLoS One (2014) 0.86
Zebrafish high-throughput screening to study the impact of dissolvable metal oxide nanoparticles on the hatching enzyme, ZHE1. Small (2012) 0.86
Innovation in academic chemical screening: filling the gaps in chemical biology. Curr Opin Chem Biol (2013) 0.85
Advanced computational modeling for in vitro nanomaterial dosimetry. Part Fibre Toxicol (2015) 0.85
In Vivo Nanotoxicity Testing using the Zebrafish Embryo Assay. J Mater Chem B Mater Biol Med (2013) 0.85
Application of magnetic nanoparticles to gene delivery. Int J Mol Sci (2011) 0.85
The role of chorion on toxicity of silver nanoparticles in the embryonic zebrafish assay. Environ Health Toxicol (2014) 0.84
TOXICITY PROFILING OF ENGINEERED NANOMATERIALS VIA MULTIVARIATE DOSE-RESPONSE SURFACE MODELING. Ann Appl Stat (2012) 0.83
Multilaboratory evaluation of 15 bioassays for (eco)toxicity screening and hazard ranking of engineered nanomaterials: FP7 project NANOVALID. Nanotoxicology (2016) 0.79
High throughput toxicity screening and intracellular detection of nanomaterials. Wiley Interdiscip Rev Nanomed Nanobiotechnol (2016) 0.78
Hierarchical Rank Aggregation with Applications to Nanotoxicology. J Agric Biol Environ Stat (2013) 0.78
A novel liposome-based nanocarrier loaded with an LPS-dsRNA cocktail for fish innate immune system stimulation. PLoS One (2013) 0.77
Test strategy for assessing the risks of nanomaterials in the environment considering general regulatory procedures. Environ Sci Eur (2015) 0.77
Polyethylene glycol modification decreases the cardiac toxicity of carbonaceous dots in mouse and zebrafish models. Acta Pharmacol Sin (2015) 0.76
Acute effects of TiO2 nanomaterials on the viability and taxonomic composition of aquatic bacterial communities assessed via high-throughput screening and next generation sequencing. PLoS One (2014) 0.76
Direct stimulation of human fibroblasts by nCeO2 in vitro is attenuated with an amorphous silica coating. Part Fibre Toxicol (2016) 0.76
The impact of species and cell type on the nanosafety profile of iron oxide nanoparticles in neural cells. J Nanobiotechnology (2016) 0.76
Oxidative stress response in neural stem cells exposed to different superparamagnetic iron oxide nanoparticles. Int J Nanomedicine (2016) 0.75
Preparation, characterization, and in vitro dosimetry of dispersed, engineered nanomaterials. Nat Protoc (2017) 0.75
Relating Nanoparticle Properties to Biological Outcomes in Exposure Escalation Experiments. Environmetrics (2014) 0.75
Teratological effects of a panel of sixty water-soluble toxicants on zebrafish development. Zebrafish (2014) 0.75
Genotoxic capacity of Cd/Se semiconductor quantum dots with differing surface chemistries. Mutagenesis (2015) 0.75
The neglected nano-specific toxicity of ZnO nanoparticles in the yeast Saccharomyces cerevisiae. Sci Rep (2016) 0.75
ZEBRAFISH AS AN IN VIVO MODEL FOR SUSTAINABLE CHEMICAL DESIGN. Green Chem (2016) 0.75
The Developmental Toxicity of Complex Silica-Embedded Nickel Nanoparticles Is Determined by Their Physicochemical Properties. PLoS One (2016) 0.75
Silver nanoparticles incite size- and dose-dependent developmental phenotypes and nanotoxicity in zebrafish embryos. Chem Res Toxicol (2013) 0.75
Structure Activity Relationships of Engineered Nanomaterials in inducing NLRP3 Inflammasome Activation and Chronic Lung Fibrosis. NanoImpact (2016) 0.75
Facilitation of trace metal uptake in cells by inulin coating of metallic nanoparticles. R Soc Open Sci (2017) 0.75
Toxic potential of materials at the nanolevel. Science (2006) 19.24
TM4 microarray software suite. Methods Enzymol (2006) 13.78
Understanding biophysicochemical interactions at the nano-bio interface. Nat Mater (2009) 11.95
A toxicologic review of quantum dots: toxicity depends on physicochemical and environmental factors. Environ Health Perspect (2006) 6.66
Comparison of the mechanism of toxicity of zinc oxide and cerium oxide nanoparticles based on dissolution and oxidative stress properties. ACS Nano (2008) 5.68
In vitro toxicity of nanoparticles in BRL 3A rat liver cells. Toxicol In Vitro (2005) 4.47
Comparison of the abilities of ambient and manufactured nanoparticles to induce cellular toxicity according to an oxidative stress paradigm. Nano Lett (2006) 4.44
Cytotoxicity of colloidal CdSe and CdSe/ZnS nanoparticles. Nano Lett (2005) 3.65
Evaluation and comparison of gene clustering methods in microarray analysis. Bioinformatics (2006) 3.16
Toxicology for the twenty-first century. Nature (2009) 2.81
Cationic polystyrene nanosphere toxicity depends on cell-specific endocytic and mitochondrial injury pathways. ACS Nano (2008) 2.73
In vivo imaging of transport and biocompatibility of single silver nanoparticles in early development of zebrafish embryos. ACS Nano (2007) 2.67
Use of a rapid cytotoxicity screening approach to engineer a safer zinc oxide nanoparticle through iron doping. ACS Nano (2010) 2.29
Twenty-eight-day oral toxicity, genotoxicity, and gender-related tissue distribution of silver nanoparticles in Sprague-Dawley rats. Inhal Toxicol (2008) 2.25
High-throughput in vivo vertebrate screening. Nat Methods (2010) 2.20
Proinflammogenic effects of low-toxicity and metal nanoparticles in vivo and in vitro: highlighting the role of particle surface area and surface reactivity. Inhal Toxicol (2007) 2.06
Toxicity assessments of multisized gold and silver nanoparticles in zebrafish embryos. Small (2009) 1.95
Toxicity of silver nanoparticles in zebrafish models. Nanotechnology (2008) 1.89
Exposure-related health effects of silver and silver compounds: a review. Ann Occup Hyg (2005) 1.87
Dispersion and stability optimization of TiO2 nanoparticles in cell culture media. Environ Sci Technol (2010) 1.84
Decreased dissolution of ZnO by iron doping yields nanoparticles with reduced toxicity in the rodent lung and zebrafish embryos. ACS Nano (2011) 1.75
A predictive toxicological paradigm for the safety assessment of nanomaterials. ACS Nano (2009) 1.75
Twenty-eight-day inhalation toxicity study of silver nanoparticles in Sprague-Dawley rats. Inhal Toxicol (2007) 1.74
Concept of assessing nanoparticle hazards considering nanoparticle dosemetric and chemical/biological response metrics. J Toxicol Environ Health A (2010) 1.61
Nanotechnology. Can high-speed tests sort out which nanomaterials are safe? Science (2008) 1.59
From ecotoxicology to nanoecotoxicology. Toxicology (2009) 1.54
New clues for platinum antitumor chemistry: kinetically controlled metal binding to DNA. Proc Natl Acad Sci U S A (2003) 1.51
Cell death mechanisms and their implications in toxicology. Toxicol Sci (2010) 1.43
Current in vitro methods in nanoparticle risk assessment: limitations and challenges. Eur J Pharm Biopharm (2008) 1.32
Zebrafish as a correlative and predictive model for assessing biomaterial nanotoxicity. Adv Drug Deliv Rev (2009) 1.26
Comparison of the toxicity of silver, gold and platinum nanoparticles in developing zebrafish embryos. Nanotoxicology (2010) 1.24
Interactions between mammalian cell DNA and inorganic platinum compounds. II. Interstrand cross-linking of isolated and cellular DNA by platinum(IV) compounds. Biochem Pharmacol (1974) 1.24
Nanoscale and fine zinc oxide particles: can in vitro assays accurately forecast lung hazards following inhalation exposures? Environ Sci Technol (2009) 1.22
Quantum dot nanotoxicity assessment using the zebrafish embryo. Environ Sci Technol (2009) 1.18
Swimming into the future of drug discovery: in vivo chemical screens in zebrafish. ACS Chem Biol (2010) 1.16
The impact of ZnO nanoparticle aggregates on the embryonic development of zebrafish (Danio rerio). Nanotechnology (2009) 1.12
Self-organizing map analysis of toxicity-related cell signaling pathways for metal and metal oxide nanoparticles. Environ Sci Technol (2011) 1.11
Metal-fume fever from inhaling zinc oxide. AMA Arch Ind Health (1957) 0.97
Development of pulmonary tolerance in mice exposed to zinc oxide fumes. Toxicol Sci (2001) 0.96
Cisplatin-induced toxicity is associated with platinum deposition in mouse kidney mitochondria in vivo and with selective inactivation of the alpha-ketoglutarate dehydrogenase complex in LLC-PK1 cells. Biochemistry (2006) 0.93
Clustering algorithms: on learning, validation, performance, and applications to genomics. Curr Genomics (2009) 0.92
Central nervous system effects of chronic toluene abuse--clinical, brainstem evoked response and magnetic resonance imaging studies. Neurotoxicol Teratol (1989) 0.92
Toluene-induced oxidative stress in several brain regions and other organs. Mol Chem Neuropathol (1993) 0.87
Increased cytosolic Ca2+ amplifies oxygen radical-induced alterations of the ultrastructure and the energy metabolism of isolated rat pancreatic acinar cells. Digestion (1998) 0.86
Consequences of cadmium toxicity in rat hepatocytes: mitochondrial dysfunction and lipid peroxidation. Toxicology (1986) 0.86
Influence of the composition of natural organic matter on Pb bioavailability to microalgae. Environ Sci Technol (2005) 0.82
Mining biological data using self-organizing map. J Chem Inf Comput Sci (2003) 0.82
Uptake of platinum by zebrafish (Danio rerio) and ramshorn snail (Marisa cornuarietis) and resulting effects on early embryogenesis. Chemosphere (2009) 0.79
Sub-chronic toxicity of low concentrations of industrial volatile organic pollutants in vitro. Toxicol Appl Pharmacol (2006) 0.77
Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N Engl J Med (2000) 48.03
Toxic potential of materials at the nanolevel. Science (2006) 19.24
Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive. Nat Cell Biol (2004) 12.12
Understanding biophysicochemical interactions at the nano-bio interface. Nat Mater (2009) 11.95
Higher versus lower positive end-expiratory pressures in patients with the acute respiratory distress syndrome. N Engl J Med (2004) 11.78
Translating the A1C assay into estimated average glucose values. Diabetes Care (2008) 11.55
Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM. Cancer Res (2004) 9.70
Genome-wide association studies of 14 agronomic traits in rice landraces. Nat Genet (2010) 8.75
Heritable gene targeting in zebrafish using customized TALENs. Nat Biotechnol (2011) 8.34
Pulmonary-artery versus central venous catheter to guide treatment of acute lung injury. N Engl J Med (2006) 7.97
Human capillary morphogenesis protein 2 functions as an anthrax toxin receptor. Proc Natl Acad Sci U S A (2003) 5.95
Transplantation and in vivo imaging of multilineage engraftment in zebrafish bloodless mutants. Nat Immunol (2003) 5.73
Mutations in BRAF and KRAS characterize the development of low-grade ovarian serous carcinoma. J Natl Cancer Inst (2003) 5.64
Donor-derived brain tumor following neural stem cell transplantation in an ataxia telangiectasia patient. PLoS Med (2009) 5.50
Randomized, placebo-controlled clinical trial of an aerosolized β₂-agonist for treatment of acute lung injury. Am J Respir Crit Care Med (2011) 5.24
A map of rice genome variation reveals the origin of cultivated rice. Nature (2012) 4.92
Skeletal muscle-specific ablation of raptor, but not of rictor, causes metabolic changes and results in muscle dystrophy. Cell Metab (2008) 4.91
BRAF mutation predicts a poorer clinical prognosis for papillary thyroid cancer. J Clin Endocrinol Metab (2005) 4.39
Five-year outcomes of the China National Free Antiretroviral Treatment Program. Ann Intern Med (2009) 4.21
Genome-wide association study of flowering time and grain yield traits in a worldwide collection of rice germplasm. Nat Genet (2011) 4.19
Multifunctional inorganic nanoparticles for imaging, targeting, and drug delivery. ACS Nano (2008) 3.88
Effect of earlier initiation of antiretroviral treatment and increased treatment coverage on HIV-related mortality in China: a national observational cohort study. Lancet Infect Dis (2011) 3.85
L-methylfolate as adjunctive therapy for SSRI-resistant major depression: results of two randomized, double-blind, parallel-sequential trials. Am J Psychiatry (2012) 3.73
Whole blood and leukocyte RNA isolation for gene expression analyses. Physiol Genomics (2004) 3.22
The effects of dexpramipexole (KNS-760704) in individuals with amyotrophic lateral sclerosis. Nat Med (2011) 3.16
Myc-induced T cell leukemia in transgenic zebrafish. Science (2003) 3.15
Cytotoxicity of carbon nanomaterials: single-wall nanotube, multi-wall nanotube, and fullerene. Environ Sci Technol (2005) 3.12
Prestin-based outer hair cell motility is necessary for mammalian cochlear amplification. Neuron (2008) 2.98
Identifying the proteins to which small-molecule probes and drugs bind in cells. Proc Natl Acad Sci U S A (2009) 2.94
Safety and efficacy of lithium in combination with riluzole for treatment of amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled trial. Lancet Neurol (2010) 2.91
Function annotation of the rice transcriptome at single-nucleotide resolution by RNA-seq. Genome Res (2010) 2.73
The Chinese free antiretroviral treatment program: challenges and responses. AIDS (2007) 2.73
Chromosomal deletions and inversions mediated by TALENs and CRISPR/Cas in zebrafish. Nucleic Acids Res (2013) 2.73
Ribosomal protein S19 deficiency in zebrafish leads to developmental abnormalities and defective erythropoiesis through activation of p53 protein family. Blood (2008) 2.68
Differential regulation of distinct Vps34 complexes by AMPK in nutrient stress and autophagy. Cell (2013) 2.66
TALEN-mediated precise genome modification by homologous recombination in zebrafish. Nat Methods (2013) 2.64
Increased cardiovascular disease risk indices in HIV-infected women. J Acquir Immune Defic Syndr (2005) 2.63
Effects of recruitment maneuvers in patients with acute lung injury and acute respiratory distress syndrome ventilated with high positive end-expiratory pressure. Crit Care Med (2003) 2.63
Current progress of China's free ART program. Cell Res (2005) 2.59
The effect of highly active antiretroviral therapy on mortality among HIV-infected former plasma donors in China. Clin Infect Dis (2008) 2.56
The Human MitoChip: a high-throughput sequencing microarray for mitochondrial mutation detection. Genome Res (2004) 2.54
PI(3,5)P(2) controls membrane trafficking by direct activation of mucolipin Ca(2+) release channels in the endolysosome. Nat Commun (2010) 2.54
DeltaNp63alpha and TAp63alpha regulate transcription of genes with distinct biological functions in cancer and development. Cancer Res (2003) 2.46
Gold Nanorods Mediate Tumor Cell Death by Compromising Membrane Integrity. Adv Mater (2007) 2.46
ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification. Cell Stem Cell (2008) 2.46
An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomised, first-in-man study. Lancet Neurol (2013) 2.43
A broad-spectrum antiviral targeting entry of enveloped viruses. Proc Natl Acad Sci U S A (2010) 2.41
Antiretroviral therapy to prevent HIV transmission in serodiscordant couples in China (2003-11): a national observational cohort study. Lancet (2012) 2.41
The role of oxidative stress in ambient particulate matter-induced lung diseases and its implications in the toxicity of engineered nanoparticles. Free Radic Biol Med (2008) 2.37
Engineered design of mesoporous silica nanoparticles to deliver doxorubicin and P-glycoprotein siRNA to overcome drug resistance in a cancer cell line. ACS Nano (2010) 2.36
Ets1-related protein is a key regulator of vasculogenesis in zebrafish. PLoS Biol (2006) 2.35
Use of metal oxide nanoparticle band gap to develop a predictive paradigm for oxidative stress and acute pulmonary inflammation. ACS Nano (2012) 2.35
Glucose metabolism in patients with schizophrenia treated with atypical antipsychotic agents: a frequently sampled intravenous glucose tolerance test and minimal model analysis. Arch Gen Psychiatry (2005) 2.35
TIF1gamma controls erythroid cell fate by regulating transcription elongation. Cell (2010) 2.33
The small molecule harmine is an antidiabetic cell-type-specific regulator of PPARgamma expression. Cell Metab (2007) 2.32
Use of a rapid cytotoxicity screening approach to engineer a safer zinc oxide nanoparticle through iron doping. ACS Nano (2010) 2.29
Beyond mortality: future clinical research in acute lung injury. Am J Respir Crit Care Med (2010) 2.28
Rapid analysis of angiogenesis drugs in a live fluorescent zebrafish assay. Arterioscler Thromb Vasc Biol (2003) 2.26
Genetic deletion of ghrelin does not decrease food intake but influences metabolic fuel preference. Proc Natl Acad Sci U S A (2004) 2.23
Stability and aggregation of metal oxide nanoparticles in natural aqueous matrices. Environ Sci Technol (2010) 2.21
A small molecule that binds Hedgehog and blocks its signaling in human cells. Nat Chem Biol (2009) 2.21
Hyperthermic effects of gold nanorods on tumor cells. Nanomedicine (Lond) (2007) 2.20
Protein corona fingerprinting predicts the cellular interaction of gold and silver nanoparticles. ACS Nano (2014) 2.17
Comparison of analysis approaches for phase III clinical trials in amyotrophic lateral sclerosis. Muscle Nerve (2012) 2.13
Pivotal contributions of megakaryocytes to the biology of idiopathic myelofibrosis. Blood (2007) 2.09
Magnetic resonance imaging by synergistic diffusion-diffraction patterns. Phys Rev Lett (2012) 2.02
Irisin stimulates browning of white adipocytes through mitogen-activated protein kinase p38 MAP kinase and ERK MAP kinase signaling. Diabetes (2013) 2.02
Genome-wide scan for familial nasopharyngeal carcinoma reveals evidence of linkage to chromosome 4. Nat Genet (2002) 2.00
An estimator for treatment comparisons among survivors in randomized trials. Biometrics (2005) 2.00
Interferon-induced transmembrane protein-3 genetic variant rs12252-C is associated with severe influenza in Chinese individuals. Nat Commun (2013) 2.00
Autonomous in vitro anticancer drug release from mesoporous silica nanoparticles by pH-sensitive nanovalves. J Am Chem Soc (2010) 1.99
Genomic analyses of the microsporidian Nosema ceranae, an emergent pathogen of honey bees. PLoS Pathog (2009) 1.97
Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Proc Natl Acad Sci U S A (2007) 1.96
The activation domains, the proline-rich domain, and the C-terminal basic domain in p53 are necessary for acetylation of histones on the proximal p21 promoter and interaction with p300/CREB-binding protein. J Biol Chem (2003) 1.94
A coding VKORC1 Asp36Tyr polymorphism predisposes to warfarin resistance. Blood (2006) 1.94
Spontaneous spinal epidural hematoma: analysis of 23 cases. Surg Neurol (2007) 1.94
Cloned zebrafish by nuclear transfer from long-term-cultured cells. Nat Biotechnol (2002) 1.89
Evidence of a dissociation pattern in resting-state default mode network connectivity in first-episode, treatment-naive major depression patients. Biol Psychiatry (2011) 1.87
Processing pathway dependence of amorphous silica nanoparticle toxicity: colloidal vs pyrolytic. J Am Chem Soc (2012) 1.86
Lipid storage disorders block lysosomal trafficking by inhibiting a TRP channel and lysosomal calcium release. Nat Commun (2012) 1.85
Dispersion and stability optimization of TiO2 nanoparticles in cell culture media. Environ Sci Technol (2010) 1.84