Published in Nanoscale on March 08, 2011
Deriving the consequences of genomic variants with the Ensembl API and SNP Effect Predictor. Bioinformatics (2010) 15.90
Ensembl 2011. Nucleic Acids Res (2010) 14.68
Ensembl's 10th year. Nucleic Acids Res (2009) 10.82
An overview of Ensembl. Genome Res (2004) 10.35
A first-generation linkage disequilibrium map of human chromosome 22. Nature (2002) 7.03
The DNA sequence of the human X chromosome. Nature (2005) 6.97
Genome analysis of the platypus reveals unique signatures of evolution. Nature (2008) 5.74
Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer. Nat Genet (2012) 5.28
A database and API for variation, dense genotyping and resequencing data. BMC Bioinformatics (2010) 4.68
The functional spectrum of low-frequency coding variation. Genome Biol (2011) 4.42
Identification of a SUMO-binding motif that recognizes SUMO-modified proteins. Proc Natl Acad Sci U S A (2004) 4.19
Locus Reference Genomic sequences: an improved basis for describing human DNA variants. Genome Med (2010) 4.19
Insights into hominid evolution from the gorilla genome sequence. Nature (2012) 4.12
Comparative and demographic analysis of orang-utan genomes. Nature (2011) 3.83
Deleterious- and disease-allele prevalence in healthy individuals: insights from current predictions, mutation databases, and population-scale resequencing. Am J Hum Genet (2012) 3.30
Spread of an inactive form of caspase-12 in humans is due to recent positive selection. Am J Hum Genet (2006) 3.00
SNP and haplotype mapping for genetic analysis in the rat. Nat Genet (2008) 2.96
Genome-wide copy-number-variation study identified a susceptibility gene, UGT2B17, for osteoporosis. Am J Hum Genet (2008) 2.65
Small ubiquitin-like modifier (SUMO) recognition of a SUMO binding motif: a reversal of the bound orientation. J Biol Chem (2005) 2.44
How is mRNA expression predictive for protein expression? A correlation study on human circulating monocytes. Acta Biochim Biophys Sin (Shanghai) (2008) 2.19
Repair of methylation damage in DNA and RNA by mammalian AlkB homologues. J Biol Chem (2005) 2.19
The intrinsic affinity between E2 and the Cys domain of E1 in ubiquitin-like modifications. Mol Cell (2007) 2.05
Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts. Proc Natl Acad Sci U S A (2012) 1.94
Elevated expression of CUEDC2 protein confers endocrine resistance in breast cancer. Nat Med (2011) 1.93
Mice lacking sodium channel beta1 subunits display defects in neuronal excitability, sodium channel expression, and nodal architecture. J Neurosci (2004) 1.92
Unique binding interactions among Ubc9, SUMO and RanBP2 reveal a mechanism for SUMO paralog selection. Nat Struct Mol Biol (2004) 1.90
Curve analysis of the aging orbital aperture. Plast Reconstr Surg (2002) 1.87
A calibrated human Y-chromosomal phylogeny based on resequencing. Genome Res (2012) 1.83
Impact of the bag exchange procedure on risk of peritonitis. Perit Dial Int (2010) 1.80
Solution structure of the C-terminal domain of Ku80 suggests important sites for protein-protein interactions. Structure (2004) 1.78
Botulinum toxin type A for the treatment of trigeminal neuralgia: results from a randomized, double-blind, placebo-controlled trial. Cephalalgia (2012) 1.78
Antibacterial activity of graphite, graphite oxide, graphene oxide, and reduced graphene oxide: membrane and oxidative stress. ACS Nano (2011) 1.78
Sequential posttranslational modifications program FEN1 degradation during cell-cycle progression. Mol Cell (2012) 1.76
Identification of a substrate recognition site on Ubc9. J Biol Chem (2002) 1.71
Role of an N-terminal site of Ubc9 in SUMO-1, -2, and -3 binding and conjugation. Biochemistry (2003) 1.70
Stabilization of G-quadruplex DNA and down-regulation of oncogene c-myc by quindoline derivatives. J Med Chem (2007) 1.70
Reduced sodium channel density, altered voltage dependence of inactivation, and increased susceptibility to seizures in mice lacking sodium channel beta 2-subunits. Proc Natl Acad Sci U S A (2002) 1.52
Transcriptional dynamics of bile salt export pump during pregnancy: mechanisms and implications in intrahepatic cholestasis of pregnancy. Hepatology (2014) 1.48
EGFR mutation detection in NSCLC--assessment of diagnostic application and recommendations of the German Panel for Mutation Testing in NSCLC. Virchows Arch (2010) 1.45
Genetic basis of Y-linked hearing impairment. Am J Hum Genet (2013) 1.42
Genome-wide association study identifies ALDH7A1 as a novel susceptibility gene for osteoporosis. PLoS Genet (2010) 1.41
Genome-wide association study suggested copy number variation may be associated with body mass index in the Chinese population. J Hum Genet (2009) 1.40
Mesenchymal stem cells induce mature dendritic cells into a novel Jagged-2-dependent regulatory dendritic cell population. Blood (2008) 1.39
A young Drosophila duplicate gene plays essential roles in spermatogenesis by regulating several Y-linked male fertility genes. PLoS Genet (2010) 1.35
Sharper and faster "nano darts" kill more bacteria: a study of antibacterial activity of individually dispersed pristine single-walled carbon nanotube. ACS Nano (2009) 1.29
The DNA-binding properties of the ARID-containing subunits of yeast and mammalian SWI/SNF complexes. Nucleic Acids Res (2004) 1.21
A new permutation strategy of pathway-based approach for genome-wide association study. BMC Bioinformatics (2009) 1.19
Associations of HLA-DP variants with hepatitis B virus infection in southern and northern Han Chinese populations: a multicenter case-control study. PLoS One (2011) 1.19
Multistage genome-wide association meta-analyses identified two new loci for bone mineral density. Hum Mol Genet (2013) 1.17
Desmoplakin acts as a tumor suppressor by inhibition of the Wnt/β-catenin signaling pathway in human lung cancer. Carcinogenesis (2012) 1.17
Sensitivity enhancement of multidimensional NMR experiments by paramagnetic relaxation effects. J Am Chem Soc (2006) 1.16
Alfuzosin delays cardiac repolarization by a novel mechanism. J Pharmacol Exp Ther (2007) 1.14
Population differentiation as an indicator of recent positive selection in humans: an empirical evaluation. Genetics (2009) 1.13
Immunoprofiles of 11 biomarkers using tissue microarrays identify prognostic subgroups in colorectal cancer. Neoplasia (2005) 1.13
The Cryptococcus neoformans transcriptome at the site of human meningitis. MBio (2014) 1.11
Using chimeric mice with humanized livers to predict human drug metabolism and a drug-drug interaction. J Pharmacol Exp Ther (2012) 1.11
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicol Sci (2013) 1.11
Metabolic activation of nevirapine in human liver microsomes: dehydrogenation and inactivation of cytochrome P450 3A4. Drug Metab Dispos (2009) 1.10
Loss of desmocollin 1-3 and homeobox genes PITX1 and CDX2 are associated with tumor progression and survival in colorectal carcinoma. Int J Colorectal Dis (2012) 1.10
Mesenchymal stem cells derived from human umbilical cord ameliorate ischemia/reperfusion-induced acute renal failure in rats. Biotechnol Lett (2010) 1.09
Isolation and comparison of mesenchymal stem-like cells from human gastric cancer and adjacent non-cancerous tissues. J Cancer Res Clin Oncol (2010) 1.09
Activation of RXR and RAR signaling promotes myogenic differentiation of myoblastic C2C12 cells. Differentiation (2009) 1.09
Cdk1-phosphorylated CUEDC2 promotes spindle checkpoint inactivation and chromosomal instability. Nat Cell Biol (2011) 1.08
FGFR1 expression and gene copy numbers in human lung cancer. Virchows Arch (2012) 1.07
A SNP map of the rat genome generated from cDNA sequences. Science (2004) 1.06
Insights into high affinity small ubiquitin-like modifier (SUMO) recognition by SUMO-interacting motifs (SIMs) revealed by a combination of NMR and peptide array analysis. J Biol Chem (2011) 1.06
Reduced expression of desmocollin 2 is an independent prognostic biomarker for shorter patients survival in pancreatic ductal adenocarcinoma. J Clin Pathol (2011) 1.06
Toward the extraction of single species of single-walled carbon nanotubes using fluorene-based polymers. Nano Lett (2007) 1.05
Lateral dimension-dependent antibacterial activity of graphene oxide sheets. Langmuir (2012) 1.05
Identification of biomarkers to distinguish clear cell sarcoma from malignant melanoma. Hum Pathol (2012) 1.04
Isoform-specific monobody inhibitors of small ubiquitin-related modifiers engineered using structure-guided library design. Proc Natl Acad Sci U S A (2011) 1.03
Characterization of TRZ1, a yeast homolog of the human candidate prostate cancer susceptibility gene ELAC2 encoding tRNase Z. BMC Mol Biol (2005) 1.03
Presence of qnr gene in Escherichia coli and Klebsiella pneumoniae resistant to ciprofloxacin isolated from pediatric patients in China. BMC Infect Dis (2008) 1.02
Baiji genomes reveal low genetic variability and new insights into secondary aquatic adaptations. Nat Commun (2013) 1.01
Conformational transition associated with E1-E2 interaction in small ubiquitin-like modifications. J Biol Chem (2009) 1.01
Large pi-aromatic molecules as potential sensitizers for highly efficient dye-sensitized solar cells. Acc Chem Res (2009) 1.00
In vivo genome-wide expression study on human circulating B cells suggests a novel ESR1 and MAPK3 network for postmenopausal osteoporosis. J Bone Miner Res (2008) 1.00
SUMO conjugation to the matrix attachment region-binding protein, special AT-rich sequence-binding protein-1 (SATB1), targets SATB1 to promyelocytic nuclear bodies where it undergoes caspase cleavage. J Biol Chem (2008) 0.99
Creation of pure nanodrugs and their anticancer properties. Angew Chem Int Ed Engl (2012) 0.99
Clinical characteristics and outcomes of "silent" and "non-silent" peritonitis in patients on peritoneal dialysis. Perit Dial Int (2012) 0.98
Human genomic regions with exceptionally high levels of population differentiation identified from 911 whole-genome sequences. Genome Biol (2014) 0.98
Mechanism of E1-E2 interaction for the inhibition of Ubl adenylation. J Biol Chem (2010) 0.97
Hydrogen-bonding dynamics in photoinduced electron transfer in a ferrocene-quinone linked dyad with a rigid amide spacer. J Am Chem Soc (2002) 0.97
Structural basis for calmodulin as a dynamic calcium sensor. Structure (2012) 0.97
Alkylation of cysteine 468 in Stat3 defines a novel site for therapeutic development. ACS Chem Biol (2011) 0.97
Phosphorylation-dependent interaction of SATB1 and PIAS1 directs SUMO-regulated caspase cleavage of SATB1. Mol Cell Biol (2010) 0.97
Photovoltaic cells using composite nanoclusters of porphyrins and fullerenes with gold nanoparticles. J Am Chem Soc (2005) 0.97
Role of two residues proximal to the active site of Ubc9 in substrate recognition by the Ubc9.SUMO-1 thiolester complex. Biochemistry (2003) 0.96
Antibiotic use in five children's hospitals during 2002-2006: the impact of antibiotic guidelines issued by the Chinese Ministry of Health. Pharmacoepidemiol Drug Saf (2008) 0.96
High altitude adaptation in Daghestani populations from the Caucasus. Hum Genet (2011) 0.96
Characterization of the 3' --> 5' exonuclease activity found in human nucleoside diphosphate kinase 1 (NDK1) and several of its homologues. Biochemistry (2005) 0.96
Brain-derived neurotrophic factor contributes to spinal long-term potentiation and mechanical hypersensitivity by activation of spinal microglia in rat. Brain Behav Immun (2010) 0.95
Association analyses of RANKL/RANK/OPG gene polymorphisms with femoral neck compression strength index variation in Caucasians. Calcif Tissue Int (2009) 0.95
SUMOylation attenuates sensitivity toward hypoxia- or desferroxamine-induced injury by modulating adaptive responses in salivary epithelial cells. Am J Pathol (2006) 0.95
Occurrence of qnr-positive clinical isolates in Klebsiella pneumoniae producing ESBL or AmpC-type beta-lactamase from five pediatric hospitals in China. FEMS Microbiol Lett (2008) 0.95
Human complement factor H is a novel diagnostic marker for lung adenocarcinoma. Int J Oncol (2011) 0.95
[Clinical study on combination of acupuncture, cupping and medicine for treatment of fibromyalgia syndrome]. Zhongguo Zhen Jiu (2006) 0.94
FOXP2 targets show evidence of positive selection in European populations. Am J Hum Genet (2013) 0.94
High-purity separation of gold nanoparticle dimers and trimers. J Am Chem Soc (2009) 0.94