Local activation of CD8 T cells and systemic tumor eradication without toxicity via slow release and local delivery of agonistic CD40 antibody.

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Published in Clin Cancer Res on March 09, 2011

Authors

Marieke F Fransen1, Marjolein Sluijter, Hans Morreau, Ramon Arens, Cornelis J M Melief

Author Affiliations

1: Department of Immunohematology and Blood Transfusion, Leiden University Medical Center; ISA Pharmaceuticals, Leiden, the Netherlands.

Associated clinical trials:

Phase I-II Study of Intratumoral Urelumab Combined With Nivolumab in Patients With Solid Tumors (INTRUST) | NCT03792724

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