Published in PLoS Genet on March 03, 2011
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Adjustment for population stratification via principal components in association analysis of rare variants. Genet Epidemiol (2012) 1.03
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Region-based association analysis of human quantitative traits in related individuals. PLoS One (2013) 0.97
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A data-driven method for identifying rare variants with heterogeneous trait effects. Genet Epidemiol (2011) 0.95
Identifying rare variants associated with complex traits via sequencing. Curr Protoc Hum Genet (2013) 0.95
Multiple regression methods show great potential for rare variant association tests. PLoS One (2012) 0.95
Utilizing population controls in rare-variant case-parent association tests. Am J Hum Genet (2014) 0.92
The admixture maximum likelihood test to test for association between rare variants and disease phenotypes. BMC Bioinformatics (2013) 0.91
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FamLBL: detecting rare haplotype disease association based on common SNPs using case-parent triads. Bioinformatics (2014) 0.91
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FFBSKAT: fast family-based sequence kernel association test. PLoS One (2014) 0.90
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Smoothed functional principal component analysis for testing association of the entire allelic spectrum of genetic variation. Eur J Hum Genet (2012) 0.89
Filtering genetic variants and placing informative priors based on putative biological function. BMC Genet (2016) 0.89
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Mining the LIPG allelic spectrum reveals the contribution of rare and common regulatory variants to HDL cholesterol. PLoS Genet (2011) 0.88
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A flexible approach for the analysis of rare variants allowing for a mixture of effects on binary or quantitative traits. PLoS Genet (2013) 0.88
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SNPs3D: candidate gene and SNP selection for association studies. BMC Bioinformatics (2006) 21.54
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A groupwise association test for rare mutations using a weighted sum statistic. PLoS Genet (2009) 19.64
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Discovering genetic ancestry using spectral graph theory. Genet Epidemiol (2010) 3.03
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Genetic determinants of QT interval variation and sudden cardiac death. Curr Opin Genet Dev (2007) 1.38
PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet (2007) 209.92
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A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
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Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science (2007) 51.70
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Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature (2009) 33.26
Integrating common and rare genetic variation in diverse human populations. Nature (2010) 32.30
The landscape of somatic copy-number alteration across human cancers. Nature (2010) 31.88
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat Genet (2008) 30.20
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A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science (2006) 27.49
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Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
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Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35
Detecting recent positive selection in the human genome from haplotype structure. Nature (2002) 22.00
Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. Nat Genet (2008) 20.73
Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet (2008) 20.66
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
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New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
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