Published in Development on March 29, 2011
Uniting germline and stem cells: the function of Piwi proteins and the piRNA pathway in diverse organisms. Annu Rev Genet (2011) 2.07
RNA granules in germ cells. Cold Spring Harb Perspect Biol (2011) 1.80
Heterotypic piRNA Ping-Pong requires qin, a protein with both E3 ligase and Tudor domains. Mol Cell (2011) 1.79
Biology of PIWI-interacting RNAs: new insights into biogenesis and function inside and outside of germlines. Genes Dev (2012) 1.75
Deciphering arginine methylation: Tudor tells the tale. Nat Rev Mol Cell Biol (2011) 1.69
A systematic analysis of Drosophila TUDOR domain-containing proteins identifies Vreteno and the Tdrd12 family as essential primary piRNA pathway factors. EMBO J (2011) 1.58
Tdrkh is essential for spermatogenesis and participates in primary piRNA biogenesis in the germline. EMBO J (2013) 1.22
Mitochondrial protein BmPAPI modulates the length of mature piRNAs. RNA (2013) 1.07
Next generation organelles: structure and role of germ granules in the germline. Mol Reprod Dev (2012) 1.01
Posttranscriptional regulation of gene expression by Piwi proteins and piRNAs. Mol Cell (2014) 0.96
Tdrd1 acts as a molecular scaffold for Piwi proteins and piRNA targets in zebrafish. EMBO J (2011) 0.95
PIWI proteins and their interactors in piRNA biogenesis, germline development and gene expression. Natl Sci Rev (2014) 0.92
Identification and Functional Analysis of the Pre-piRNA 3' Trimmer in Silkworms. Cell (2016) 0.90
The Tudor domain protein Tapas, a homolog of the vertebrate Tdrd7, functions in the piRNA pathway to regulate retrotransposons in germline of Drosophila melanogaster. BMC Biol (2014) 0.89
The RNase PARN-1 Trims piRNA 3' Ends to Promote Transcriptome Surveillance in C. elegans. Cell (2016) 0.87
Aub and Ago3 Are Recruited to Nuage through Two Mechanisms to Form a Ping-Pong Complex Assembled by Krimper. Mol Cell (2015) 0.82
Distinct features of the piRNA pathway in somatic and germ cells: from piRNA cluster transcription to piRNA processing and amplification. Mob DNA (2014) 0.80
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Piwi maintains germline stem cells and oogenesis in Drosophila through negative regulation of Polycomb group proteins. Nat Genet (2016) 0.78
The piRNA Pathway Guards the Germline Genome Against Transposable Elements. Adv Exp Med Biol (2016) 0.77
The Drosophila Su(var)3-7 gene is required for oogenesis and female fertility, genetically interacts with piwi and aubergine, but impacts only weakly transposon silencing. PLoS One (2014) 0.77
Tudor-SN Interacts with Piwi Antagonistically in Regulating Spermatogenesis but Synergistically in Silencing Transposons in Drosophila. PLoS Genet (2016) 0.76
Zfrp8 forms a complex with fragile-X mental retardation protein and regulates its localization and function. Dev Biol (2016) 0.76
Capturing the cloud: UAP56 in nuage assembly and function. Cell (2012) 0.76
Piwi Proteins and piRNAs step onto the systems biology stage. Adv Exp Med Biol (2014) 0.76
Stable intronic sequence RNAs have possible regulatory roles in Drosophila melanogaster. J Cell Biol (2015) 0.75
Diversity of the piRNA pathway for nonself silencing: worm-specific piRNA biogenesis factors. Genes Dev (2014) 0.75
Caenorhabditis elegans RSD-2 and RSD-6 promote germ cell immortality by maintaining small interfering RNA populations. Proc Natl Acad Sci U S A (2014) 0.75
Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila. Cell (2007) 18.35
Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans. Cell (2006) 15.12
MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies. Nat Cell Biol (2005) 12.12
A distinct small RNA pathway silences selfish genetic elements in the germline. Science (2006) 11.63
A slicer-mediated mechanism for repeat-associated siRNA 5' end formation in Drosophila. Science (2007) 10.73
P bodies and the control of mRNA translation and degradation. Mol Cell (2007) 9.98
A germline-specific class of small RNAs binds mammalian Piwi proteins. Nature (2006) 9.88
The Piwi-piRNA pathway provides an adaptive defense in the transposon arms race. Science (2007) 9.36
A novel class of small RNAs bind to MILI protein in mouse testes. Nature (2006) 8.80
P bodies: at the crossroads of post-transcriptional pathways. Nat Rev Mol Cell Biol (2007) 7.96
Double-stranded RNA-mediated silencing of genomic tandem repeats and transposable elements in the D. melanogaster germline. Curr Biol (2001) 7.06
A novel class of evolutionarily conserved genes defined by piwi are essential for stem cell self-renewal. Genes Dev (1998) 6.74
Specific association of Piwi with rasiRNAs derived from retrotransposon and heterochromatic regions in the Drosophila genome. Genes Dev (2006) 6.60
Specialized piRNA pathways act in germline and somatic tissues of the Drosophila ovary. Cell (2009) 6.39
A role for Piwi and piRNAs in germ cell maintenance and transposon silencing in Zebrafish. Cell (2007) 6.31
A three-dimensional view of the molecular machinery of RNA interference. Nature (2009) 6.31
An epigenetic role for maternally inherited piRNAs in transposon silencing. Science (2008) 5.05
Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes. Genes Dev (2006) 4.97
P-body formation is a consequence, not the cause, of RNA-mediated gene silencing. Mol Cell Biol (2007) 4.90
piwi encodes a nucleoplasmic factor whose activity modulates the number and division rate of germline stem cells. Development (2000) 4.54
Collapse of germline piRNAs in the absence of Argonaute3 reveals somatic piRNAs in flies. Cell (2009) 4.39
On the road to reading the RNA-interference code. Nature (2009) 4.33
Aubergine encodes a Drosophila polar granule component required for pole cell formation and related to eIF2C. Development (2001) 4.13
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An epigenetic activation role of Piwi and a Piwi-associated piRNA in Drosophila melanogaster. Nature (2007) 3.86
A regulatory circuit for piwi by the large Maf gene traffic jam in Drosophila. Nature (2009) 3.68
Drosophila PIWI associates with chromatin and interacts directly with HP1a. Genes Dev (2007) 3.46
The Drosophila fusome, a germline-specific organelle, contains membrane skeletal proteins and functions in cyst formation. Development (1994) 3.40
Unique germ-line organelle, nuage, functions to repress selfish genetic elements in Drosophila melanogaster. Proc Natl Acad Sci U S A (2007) 3.31
zucchini and squash encode two putative nucleases required for rasiRNA production in the Drosophila germline. Dev Cell (2007) 3.29
Me31B silences translation of oocyte-localizing RNAs through the formation of cytoplasmic RNP complex during Drosophila oogenesis. Development (2001) 3.22
The biogenesis and function of PIWI proteins and piRNAs: progress and prospect. Annu Rev Cell Dev Biol (2009) 3.21
Sorting of Drosophila small silencing RNAs partitions microRNA* strands into the RNA interference pathway. RNA (2009) 3.19
The role of PIWI and the miRNA machinery in Drosophila germline determination. Curr Biol (2006) 3.06
The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline. Dev Cell (2009) 2.96
Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family members. Genes Dev (2009) 2.95
MIWI associates with translational machinery and PIWI-interacting RNAs (piRNAs) in regulating spermatogenesis. Proc Natl Acad Sci U S A (2006) 2.80
A broadly conserved pathway generates 3'UTR-directed primary piRNAs. Curr Biol (2009) 2.69
Loss of the Mili-interacting Tudor domain-containing protein-1 activates transposons and alters the Mili-associated small RNA profile. Nat Struct Mol Biol (2009) 2.64
The Drosophila SDE3 homolog armitage is required for oskar mRNA silencing and embryonic axis specification. Cell (2004) 2.59
Arginine methylation of Piwi proteins catalysed by dPRMT5 is required for Ago3 and Aub stability. Nat Cell Biol (2009) 2.42
Tudor domains bind symmetrical dimethylated arginines. J Biol Chem (2005) 2.23
Efficient protein trafficking requires trailer hitch, a component of a ribonucleoprotein complex localized to the ER in Drosophila. Dev Cell (2005) 2.14
Mili interacts with tudor domain-containing protein 1 in regulating spermatogenesis. Curr Biol (2009) 2.13
aubergine enhances oskar translation in the Drosophila ovary. Development (1996) 1.98
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Functional involvement of Tudor and dPRMT5 in the piRNA processing pathway in Drosophila germlines. EMBO J (2009) 1.94
Tdrd6 is required for spermiogenesis, chromatoid body architecture, and regulation of miRNA expression. Curr Biol (2009) 1.81
The Sm-protein methyltransferase, dart5, is essential for germ-cell specification and maintenance. Curr Biol (2006) 1.78
Mouse Piwi interactome identifies binding mechanism of Tdrkh Tudor domain to arginine methylated Miwi. Proc Natl Acad Sci U S A (2009) 1.73
Oocyte determination and the origin of polarity in Drosophila: the role of the spindle genes. Development (1997) 1.61
Repression of retroelements in Drosophila germline via piRNA pathway by the Tudor domain protein Tejas. Curr Biol (2010) 1.57
The expression profile of purified Drosophila germline stem cells. Dev Biol (2005) 1.57
Arginine methylation of Aubergine mediates Tudor binding and germ plasm localization. RNA (2009) 1.53
Isolation of new polar granule components in Drosophila reveals P body and ER associated proteins. Mech Dev (2008) 1.48
piRNAs mediate posttranscriptional retroelement silencing and localization to pi-bodies in the Drosophila germline. J Cell Biol (2009) 1.46
Molecular evolution of piRNA and transposon control pathways in Drosophila. Cold Spring Harb Symp Quant Biol (2010) 1.21
Localization of double-stranded small interfering RNA to cytoplasmic processing bodies is Ago2 dependent and results in up-regulation of GW182 and Argonaute-2. Mol Biol Cell (2008) 1.20
Biochemical fractionation and assembly of the membrane components that mediate nascent chain targeting and translocation. Cell (1991) 1.18
nup154 genetically interacts with cup and plays a cell-type-specific function during Drosophila melanogaster egg-chamber development. Genetics (2007) 0.96
SnapShot: Fly piRNAs, PIWI proteins, and the ping-pong cycle. Cell (2009) 0.81
A novel class of small RNAs in mouse spermatogenic cells. Genes Dev (2006) 5.85
miwi, a murine homolog of piwi, encodes a cytoplasmic protein essential for spermatogenesis. Dev Cell (2002) 5.85
Mili, a mammalian member of piwi family gene, is essential for spermatogenesis. Development (2004) 5.47
MicroRNAs: key regulators of stem cells. Nat Rev Mol Cell Biol (2009) 4.26
An epigenetic activation role of Piwi and a Piwi-associated piRNA in Drosophila melanogaster. Nature (2007) 3.86
Drosophila PIWI associates with chromatin and interacts directly with HP1a. Genes Dev (2007) 3.46
Dynamic transcriptomes during neural differentiation of human embryonic stem cells revealed by short, long, and paired-end sequencing. Proc Natl Acad Sci U S A (2010) 3.28
The biogenesis and function of PIWI proteins and piRNAs: progress and prospect. Annu Rev Cell Dev Biol (2009) 3.21
The role of PIWI and the miRNA machinery in Drosophila germline determination. Curr Biol (2006) 3.06
MIWI associates with translational machinery and PIWI-interacting RNAs (piRNAs) in regulating spermatogenesis. Proc Natl Acad Sci U S A (2006) 2.80
Role for piRNAs and noncoding RNA in de novo DNA methylation of the imprinted mouse Rasgrf1 locus. Science (2011) 2.17
Mili interacts with tudor domain-containing protein 1 in regulating spermatogenesis. Curr Biol (2009) 2.13
Uniting germline and stem cells: the function of Piwi proteins and the piRNA pathway in diverse organisms. Annu Rev Genet (2011) 2.07
Molecular characterization of hiwi, a human member of the piwi gene family whose overexpression is correlated to seminomas. Oncogene (2002) 2.03
MITOPLD is a mitochondrial protein essential for nuage formation and piRNA biogenesis in the mouse germline. Dev Cell (2011) 1.94
Lin28-mediated post-transcriptional regulation of Oct4 expression in human embryonic stem cells. Nucleic Acids Res (2009) 1.93
MILI, a PIWI-interacting RNA-binding protein, is required for germ line stem cell self-renewal and appears to positively regulate translation. J Biol Chem (2008) 1.93
Genome-wide studies reveal that Lin28 enhances the translation of genes important for growth and survival of human embryonic stem cells. Stem Cells (2011) 1.90
A major epigenetic programming mechanism guided by piRNAs. Dev Cell (2013) 1.89
Regulatory relationship among piwi, pumilio, and bag-of-marbles in Drosophila germline stem cell self-renewal and differentiation. Curr Biol (2005) 1.88
Nanos maintains germline stem cell self-renewal by preventing differentiation. Science (2004) 1.74
Septic arthritis after arthroscopic anterior cruciate ligament reconstruction: a retrospective analysis of incidence, presentation, treatment, and cause. Arthroscopy (2008) 1.65
Drosophila Piwi functions in Hsp90-mediated suppression of phenotypic variation. Nat Genet (2010) 1.62
Interplay of PIWI/Argonaute protein MIWI and kinesin KIF17b in chromatoid bodies of male germ cells. J Cell Sci (2006) 1.52
Precancerous stem cells have the potential for both benign and malignant differentiation. PLoS One (2007) 1.36
Pumilio 1 suppresses multiple activators of p53 to safeguard spermatogenesis. Curr Biol (2012) 1.34
Piecing together the mosaic of early mammalian development through microRNAs. J Biol Chem (2008) 1.32
The Yb body, a major site for Piwi-associated RNA biogenesis and a gateway for Piwi expression and transport to the nucleus in somatic cells. J Biol Chem (2010) 1.30
Chromator, a novel and essential chromodomain protein interacts directly with the putative spindle matrix protein skeletor. J Cell Biochem (2004) 1.29
A high-resolution whole-genome map of key chromatin modifications in the adult Drosophila melanogaster. PLoS Genet (2011) 1.27
The Yb protein defines a novel organelle and regulates male germline stem cell self-renewal in Drosophila melanogaster. J Cell Biol (2009) 1.26
Tdrkh is essential for spermatogenesis and participates in primary piRNA biogenesis in the germline. EMBO J (2013) 1.22
Identification of Piwil2-like (PL2L) proteins that promote tumorigenesis. PLoS One (2010) 1.17
Beyond transposons: the epigenetic and somatic functions of the Piwi-piRNA mechanism. Curr Opin Cell Biol (2013) 1.16
piRNA biogenesis during adult spermatogenesis in mice is independent of the ping-pong mechanism. Cell Res (2012) 1.15
The chromodomain protein, Chromator, interacts with JIL-1 kinase and regulates the structure of Drosophila polytene chromosomes. J Cell Sci (2006) 1.04
Germline stem cells in the Drosophila ovary descend from pole cells in the anterior region of the embryonic gonad. Development (2004) 1.01
Function of Piwi, a nuclear Piwi/Argonaute protein, is independent of its slicer activity. Proc Natl Acad Sci U S A (2013) 1.00
PIWI proteins and PIWI-interacting RNAs function in Hydra somatic stem cells. Proc Natl Acad Sci U S A (2013) 0.98
High-efficiency siRNA-based gene knockdown in human embryonic stem cells. RNA (2010) 0.98
The division of Drosophila germline stem cells and their precursors requires a specific cyclin. Curr Biol (2005) 0.95
Small noncoding RNAs in the germline. Cold Spring Harb Perspect Biol (2011) 0.94
Screens for piwi suppressors in Drosophila identify dosage-dependent regulators of germline stem cell division. Genetics (2003) 0.92
Pinpointing the expression of piRNAs and function of the PIWI protein subfamily during spermatogenesis in the mouse. Dev Biol (2011) 0.91
Stem cells: to be and not to be. Nature (2003) 0.89
Relation of tunnel enlargement and tunnel placement after single-bundle anterior cruciate ligament reconstruction. Arthroscopy (2011) 0.87
Quantitative changes in the mitochondrial proteome from subjects with mild cognitive impairment, early stage, and late stage Alzheimer's disease. J Alzheimers Dis (2010) 0.86
A Drosophila chromatin factor interacts with the Piwi-interacting RNA mechanism in niche cells to regulate germline stem cell self-renewal. Genetics (2010) 0.86
Repressing the repressor: a lincRNA as a MicroRNA sponge in embryonic stem cell self-renewal. Dev Cell (2013) 0.85
Piwi genes are dispensable for normal hematopoiesis in mice. PLoS One (2013) 0.84
The miRNA Regulation of Stem Cells. Wiley Interdiscip Rev Membr Transp Signal (2011) 0.84
Essential roles of the chromatin remodeling factor BRG1 in spermatogenesis in mice. Biol Reprod (2012) 0.84
Cloning, expression, and characterization of the gsdA gene encoding thermophilic glucose-6-phosphate dehydrogenase from Aquifex aeolicus. Extremophiles (2002) 0.82
Effect of repeated freezing-thawing on the Achilles tendon of rabbits. Knee Surg Sports Traumatol Arthrosc (2010) 0.81
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Sex-lethal is a target of Bruno-mediated translational repression in promoting the differentiation of stem cell progeny during Drosophila oogenesis. Dev Biol (2006) 0.79
Protein immobilization on carbon nanotubes through a molecular adapter. J Nanosci Nanotechnol (2004) 0.78
Biosensor for asparagine using a thermostable recombinant asparaginase from Archaeoglobus fulgidus. Anal Chem (2002) 0.77
Anatomic, arthroscopically assisted, mini-open fibular collateral ligament reconstruction: an in vitro biomechanical study. Am J Sports Med (2013) 0.77
In situ forces and length patterns of the fibular collateral ligament under controlled loading: an in vitro biomechanical study using a robotic system. Knee Surg Sports Traumatol Arthrosc (2014) 0.77
High-efficiency transfection and siRNA-mediated gene knockdown in human pluripotent stem cells. Curr Protoc Stem Cell Biol (2012) 0.77
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Poreless eggshells. J Clin Invest (2015) 0.75
Chromatin immunoprecipitation assay of Piwi in Drosophila. Methods Mol Biol (2014) 0.75
Stem cells in 2009. Cell Stem Cell (2009) 0.75
A Bottom-up Synthesis of Vinyl-Cellulose Nanosheets and their Nanocomposite Hydrogels with Enhanced Strength. Biomacromolecules (2017) 0.75
Adsorption of heavy metal ions from aqueous solution by crosslinked carboxymethyl konjac glucomannan. J Hazard Mater (2006) 0.75
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