Published in Dalton Trans on April 04, 2011
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Transferring the concept of multinuclearity to ruthenium complexes for improvement of anticancer activity. J Med Chem (2009) 1.51
Studies of the in vitro anticancer, antimicrobial and antioxidant potentials of selected Yemeni medicinal plants from the island Soqotra. BMC Complement Altern Med (2009) 1.29
Exclusive platination of loop adenines in the human telomeric G-quadruplex. Org Biomol Chem (2009) 1.07
Correlations between the activities of 19 anti-tumor agents and the intracellular glutathione concentrations in a panel of 14 human cancer cell lines: comparisons with the National Cancer Institute data. Anticancer Drugs (2006) 0.95
Synthesis, crystal structure and biological activities of copper(II) complexes with chelating bidentate 2-substituted benzimidazole ligands. J Inorg Biochem (2006) 0.89
Studies of the mechanism of action of platinum(II) complexes with potent cytotoxicity in human cancer cells. J Med Chem (2009) 0.87
Trans,trans,trans-[PtIV(N3)2(OH)2(py)(NH3)]: a light-activated antitumor platinum complex that kills human cancer cells by an apoptosis-independent mechanism. Mol Cancer Ther (2012) 0.84
Anticancer activity and mode of action of titanocene C. Invest New Drugs (2010) 0.82
Identification of a glutathione peroxidase inhibitor that reverses resistance to anticancer drugs in human B-cell lymphoma cell lines. Bioorg Med Chem Lett (2012) 0.82
Synthesis, structural characterization, and in vitro antitumor activity of novel N-(6-chloro-1,1-dioxo-1,4,2-benzodithiazin-3-yl)arylsulfonamides. Bioorg Med Chem (2007) 0.81
Aroyl hydrazones of 2-phenylindole-3-carbaldehydes as novel antimitotic agents. Bioorg Med Chem (2008) 0.81
Investigation of the in vitro metabolism of the analgesic flupirtine. Drug Metab Dispos (2008) 0.80
Chiral platinum(II) metallointercalators with potent in vitro cytotoxic activity. ChemMedChem (2007) 0.80
No correlation between GSH levels in human cancer cell lines and the cell growth inhibitory activities of platinum diamine complexes. Arch Pharm (Weinheim) (2004) 0.80
Influence of pyridine versus piperidine ligands on the chemical, DNA binding and cytotoxic properties of light activated trans,trans,trans-[Pt(N3)2(OH)2(NH3)(L)]. J Inorg Biochem (2011) 0.79
DNA binding studies and cytotoxicity of a dinuclear PtII diazapyrenium-based metallo-supramolecular rectangular box. Chemistry (2012) 0.79
Cytotoxic saponins from the seeds of Pittosporum angustifolium. Z Naturforsch C (2014) 0.79
Synthesis and cytotoxic activity of imidazo[1,2-a]-1,3,5-triazine analogues of 6-mercaptopurine. Arch Pharm (Weinheim) (2008) 0.78
Triterpene glycosides from the leaves of Pittosporum angustifolium. Planta Med (2013) 0.78
Synthesis, enzymatic evaluation, and docking studies of fluorogenic caspase 8 tetrapeptide substrates. ChemMedChem (2010) 0.78
3,5,7,9-Substituted hexaazaacridines: toward structures with nearly degenerate singlet-triplet energy separations. J Org Chem (2008) 0.78
[(2-Phenylindol-3-yl)methylene]propanedinitriles inhibit the growth of breast cancer cells by cell cycle arrest in G(2)/M phase and apoptosis. Bioorg Med Chem (2007) 0.78
Structure-activity relationships of novel heteroaryl-acrylonitriles as cytotoxic and antibacterial agents. Eur J Med Chem (2007) 0.77
Nicotinamide adenine dinucleotide phosphate-regenerating system coupled to a glutathione-reductase microtiter method for determination of total glutathione concentrations in adherent growing cancer cell lines. Anal Biochem (2003) 0.77
Synthesis, crystal structure, cytotoxic and superoxide dismutase activities of copper(II) complexes of N-(4,5-dihydroimidazol-2-yl)azoles. Arch Pharm (Weinheim) (2007) 0.77
Structure-activity relationships of targeted RuII(η6-p-cymene) anticancer complexes with flavonol-derived ligands. J Med Chem (2012) 0.77
Correlations between the activities of 19 standard anticancer agents, antioxidative enzyme activities and the expression of ATP-binding cassette transporters: comparison with the National Cancer Institute data. Anticancer Drugs (2007) 0.77
Oxidation potentials of N-modified derivatives of the analgesic flupirtine linked to potassium KV 7 channel opening activity but not hepatocyte toxicity. ChemMedChem (2014) 0.76
Quantification of elastase-like activity in 13 human cancer cell lines and in an immortalized human epithelial cell line by RP-HPLC. Biol Chem (2003) 0.76
Synthesis of indirubin-N'-glycosides and their anti-proliferative activity against human cancer cell lines. Bioorg Med Chem (2008) 0.76
Dancing of the second aromatic residue around the 6,8-diazabicyclo[3.2.2]nonane framework: influence on sigma receptor affinity and cytotoxicity. J Med Chem (2009) 0.76
Characterization of chemosensitivity and resistance of human cancer cell lines to platinum(II) versus platinum(IV) anticancer agents. Anticancer Drugs (2009) 0.76
Synthesis of bicyclic sigma receptor ligands with cytotoxic activity. J Med Chem (2007) 0.75
Metabolic activation and analgesic effect of flupirtine in healthy subjects, influence of the polymorphic NAT2, UGT1A1 and GSTP1. Br J Clin Pharmacol (2015) 0.75
Sustainable synthesis and automated deposition: an accessible discovery screening library of fragment-like purines. Mol Divers (2012) 0.75
Characterization of three B-cell lymphoma cell lines from chemotherapy resistant patients with respect to in vitro sensitivity to 21 antitumor agents, ABC-transporter expression and cellular redox status. J Cancer Res Clin Oncol (2007) 0.75
Tractable synthesis of multipurpose screening compounds with under-represented molecular features for an open access screening platform. Mol Divers (2014) 0.75
Microwave-assisted synthesis and evaluation of acylhydrazones as potential inhibitors of bovine glutathione peroxidase. Mol Divers (2014) 0.75
Synthesis and in vitro anti-tumor activity of N-{1-[(3-thioxo-5,6-dihydroimidazo[2,1-c][1,2,4]thiadiazol-7-ylthio)thiocarbonyl]-2-imidazolidene}arylsulfonamides. Bioorg Med Chem Lett (2006) 0.75
2,4-Diamino-9H-pyrimido[4,5-b]indol-5-ols: synthesis, in vitro cytotoxic activity, and QSAR investigations. Bioorg Med Chem (2006) 0.75
Relationships between the structure of 6-substituted 6,8-diazabicyclo[3.2.2]nonan-2-ones and their sigma receptor affinity and cytotoxic activity. Bioorg Med Chem (2009) 0.75
Relationships between the structure of 6-allyl-6,8-diazabicyclo[3.2.2]nonane derivatives and their sigma receptor affinity and cytotoxic activity. Bioorg Med Chem (2008) 0.75
3,5,7,9-Tetraphenylhexaazaacridine: a highly stable, weakly antiaromatic species with 16 pi electrons. Angew Chem Int Ed Engl (2005) 0.75
Synthesis and biological activity of new 2-amino-8-chloro-5,5-dioxo[1,2,4]triazolo[2,3-b][1,4,2]benzodithiazines. Eur J Med Chem (2006) 0.75
Synthesis and cytotoxicity testing of novel 2-(3-substituted-6-chloro-1,1-dioxo-1,4,2-benzodithiazin-7-yl)-3-phenyl-4(3H)-quinazolinones. Arch Pharm (Weinheim) (2008) 0.75
Cytotoxic and antimicrobial activities of Cu(II), Co(II), Pt(II) and Zn(II) Complexes with N,O-chelating heterocyclic carboxylates. Arch Pharm (Weinheim) (2011) 0.75
Synthesis and biological evaluation of conformationally restricted σ(1) receptor ligands with 7,9-diazabicyclo[4.2.2]decane scaffold. Org Biomol Chem (2010) 0.75
Unusual reactivity of cytotoxic cis-dihydrazide Pt(II) complexes in aqueous solution. J Inorg Biochem (2003) 0.75
Synthesis, reactions and structure-activity relationships of 1-hydroxyspiro[2.5]cyclooct-4-en-3-ones: illudin analogs with in vitro cytotoxic activity. Bioorg Med Chem (2006) 0.75
Synthesis of novel aryl(heteroaryl)sulfonyl ureas of possible biological interest. Molecules (2010) 0.75
Evaluation of (S)- and (R)-misonidazole as GPX inhibitors: synthesis, characterization including circular dichroism and in vitro testing on bovine GPx-1. Arch Pharm (Weinheim) (2013) 0.75
Synthesis and biological activity of some 2-imidazolinylhydrazone derivatives. Acta Pol Pharm (2009) 0.75
Synthesis and pharmacological evaluation of SNC80 analogues with a bridged piperazine ring. ChemMedChem (2009) 0.75
In vitro anticancer activity and evaluation of DNA duplex binding affinity of phenyl-substituted indoloquinolines. Bioorg Med Chem Lett (2011) 0.75
Synthesis, cytotoxicity testing, and structure-activity relationships of novel 6-chloro-7-(4-phenylimino-4H-3,1-benzoxazin-2-yl)-3-(substituted)-1,4,2-benzodithiazine 1,1-dioxides. Arch Pharm (Weinheim) (2011) 0.75
Synthesis, pharmacological evaluation, and σ1 receptor interaction analysis of hydroxyethyl substituted piperazines. J Med Chem (2014) 0.75