CTLA-4 blockade increases antigen-specific CD8(+) T cells in prevaccinated patients with melanoma: three cases.

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Published in Cancer Immunol Immunother on April 05, 2011

Authors

Jianda Yuan1, Brian Ginsberg, David Page, Yanyun Li, Teresa Rasalan, Humilidad F Gallardo, Yinyan Xu, Sylvia Adams, Nina Bhardwaj, Klaus Busam, Lloyd J Old, James P Allison, Achim Jungbluth, Jedd D Wolchok

Author Affiliations

1: Immunology Program, Ludwig Center for Cancer Immunotherapy, Sloan-Kettering Institute, New York, NY 10065, USA.

Associated clinical trials:

Ipilimumab +/- Vaccine Therapy in Treating Patients With Locally Advanced, Unresectable or Metastatic Pancreatic Cancer | NCT00836407

Ipilimumab With or Without Vaccine Therapy in Treating Patients With Previously Treated Stage IV Melanoma | NCT00357461

NCT00124670

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