Published in PLoS One on March 24, 2011
Multivariate protein signatures of pre-clinical Alzheimer's disease in the Alzheimer's disease neuroimaging initiative (ADNI) plasma proteome dataset. PLoS One (2012) 1.51
Unveiling clusters of RNA transcript pairs associated with markers of Alzheimer's disease progression. PLoS One (2012) 1.18
GPU-FS-kNN: a software tool for fast and scalable kNN computation using GPUs. PLoS One (2012) 1.15
Evaluation of a previously suggested plasma biomarker panel to identify Alzheimer's disease. PLoS One (2012) 1.09
Brain amyloidosis ascertainment from cognitive, imaging, and peripheral blood protein measures. Neurology (2015) 0.88
Plasma proteomics for the identification of Alzheimer disease. Alzheimer Dis Assoc Disord (2013) 0.85
Multiplex assessment of a panel of 16 serum molecules for the differential diagnosis of Alzheimer's disease. Am J Neurodegener Dis (2013) 0.79
Altered expression of RNA splicing proteins in Alzheimer's disease patients: evidence from two microarray studies. Dement Geriatr Cogn Dis Extra (2013) 0.76
Identification of Differentially Expressed Genes through Integrated Study of Alzheimer's Disease Affected Brain Regions. PLoS One (2016) 0.76
Diagnosis of multiple cancer types by shrunken centroids of gene expression. Proc Natl Acad Sci U S A (2002) 30.32
Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins. Nat Med (2007) 6.80
Vascular endothelial growth factor B controls endothelial fatty acid uptake. Nature (2010) 3.40
A serum protein-based algorithm for the detection of Alzheimer disease. Arch Neurol (2010) 2.42
Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling. Neurobiol Aging (2010) 2.32
Region-specific neurotrophin imbalances in Alzheimer disease: decreased levels of brain-derived neurotrophic factor and increased levels of nerve growth factor in hippocampus and cortical areas. Arch Neurol (2000) 1.80
Intracerebral production of tumor necrosis factor-alpha, a local neuroprotective agent, in Alzheimer disease and vascular dementia. J Clin Immunol (1999) 1.68
Cognitive and physical activity differently modulate disease progression in the amyloid precursor protein (APP)-23 model of Alzheimer's disease. Biol Psychiatry (2006) 1.66
Binding of beta-amyloid to the p75 neurotrophin receptor induces apoptosis. A possible mechanism for Alzheimer's disease. J Clin Invest (1997) 1.66
Microglia from Creutzfeldt-Jakob disease-infected brains are infectious and show specific mRNA activation profiles. J Virol (2002) 1.59
Beta-amyloid(1-42) induces neuronal death through the p75 neurotrophin receptor. J Neurosci (2008) 1.59
Uncovering molecular biomarkers that correlate cognitive decline with the changes of hippocampus' gene expression profiles in Alzheimer's disease. PLoS One (2010) 1.41
Regional specificity of alterations in NGF, BDNF and NT-3 levels in Alzheimer's disease. Neuroreport (1996) 1.34
The role of insulin and neurotrophic factor signaling in brain aging and Alzheimer's Disease. Exp Gerontol (2006) 1.32
The p75 neurotrophin receptor promotes amyloid-beta(1-42)-induced neuritic dystrophy in vitro and in vivo. J Neurosci (2009) 1.31
Identification of a 5-protein biomarker molecular signature for predicting Alzheimer's disease. PLoS One (2008) 1.31
Identifying early markers of Alzheimer's disease using quantitative multiplex proteomic immunoassay panels. Ann N Y Acad Sci (2009) 1.24
Novel role for vascular endothelial growth factor (VEGF) receptor-1 and its ligand VEGF-B in motor neuron degeneration. J Neurosci (2008) 1.23
Identification of upregulated genes in scrapie-infected brain tissue. J Virol (2000) 1.23
Granulocyte colony stimulating factor decreases brain amyloid burden and reverses cognitive impairment in Alzheimer's mice. Neuroscience (2009) 1.22
Biological activity of nerve growth factor precursor is dependent upon relative levels of its receptors. J Biol Chem (2009) 1.21
Combinatorial optimization models for finding genetic signatures from gene expression datasets. Methods Mol Biol (2008) 1.19
Protective effects of intranasal losartan in the APP/PS1 transgenic mouse model of Alzheimer disease. Rejuvenation Res (2010) 1.19
Small molecule neurotrophin receptor ligands: novel strategies for targeting Alzheimer's disease mechanisms. Curr Alzheimer Res (2007) 1.18
Insulin-like growth factors and insulin-like growth factor binding proteins in cerebrospinal fluid and serum of patients with dementia of the Alzheimer type. J Neural Transm Park Dis Dement Sect (1993) 1.15
β-Amyloid impairs axonal BDNF retrograde trafficking. Neurobiol Aging (2009) 1.13
Abeta-specific Th2 cells provide cognitive and pathological benefits to Alzheimer's mice without infiltrating the CNS. Neurobiol Dis (2009) 1.06
Microarrays--identifying molecular portraits for prostate tumors with different Gleason patterns. Methods Mol Med (2008) 1.05
Benchmarking a memetic algorithm for ordering microarray data. Biosystems (2006) 1.04
Macrophage colony-stimulating factor augments beta-amyloid-induced interleukin-1, interleukin-6, and nitric oxide production by microglial cells. J Biol Chem (1998) 1.03
Does the p75 neurotrophin receptor mediate Abeta-induced toxicity in Alzheimer's disease? J Neurochem (2006) 1.03
Fas and Fas ligand are associated with neuritic degeneration in the AD brain and participate in beta-amyloid-induced neuronal death. Neurobiol Dis (2003) 1.03
Angiopoietin-2 confers Atheroprotection in apoE-/- mice by inhibiting LDL oxidation via nitric oxide. Circ Res (2009) 1.03
RANTES upregulation in the Alzheimer's disease brain: a possible neuroprotective role. Neurobiol Aging (2008) 1.02
Peripheral chemokine receptors, their ligands, cytokines and Alzheimer's disease. J Alzheimers Dis (2008) 1.02
Neutralization of granulocyte macrophage colony-stimulating factor decreases amyloid beta 1-42 and suppresses microglial activity in a transgenic mouse model of Alzheimer's disease. Hum Mol Genet (2009) 1.01
Serum levels of CXCL13 are elevated in active multiple sclerosis. Mult Scler (2009) 1.01
Angiogenic proteins are expressed by brain blood vessels in Alzheimer's disease. J Alzheimers Dis (2006) 1.00
A neurotrophic rationale for the therapy of neurodegenerative disorders. Curr Alzheimer Res (2009) 0.98
Akt-dependent expression of NAIP-1 protects neurons against amyloid-{beta} toxicity. J Biol Chem (2005) 0.98
Selective vulnerability in Alzheimer's disease: amyloid precursor protein and p75(NTR) interaction. Ann Neurol (2009) 0.97
Neurotrophin-3 prevents the death of adult central noradrenergic neurons in vivo. Nature (1994) 0.96
The killing of neurons by beta-amyloid peptides, prions, and pro-inflammatory cytokines. Ital J Anat Embryol (2007) 0.95
Nitric oxide synthase-3 overexpression causes apoptosis and impairs neuronal mitochondrial function: relevance to Alzheimer's-type neurodegeneration. Lab Invest (2003) 0.93
P75 neurotrophin receptor regulates expression of neural cell adhesion molecule 1. Neurobiol Dis (2005) 0.91
Fas antigen expression in brains of patients with Alzheimer-type dementia. Brain Res (1995) 0.91
Genetic signatures for a rodent model of Parkinson's disease using combinatorial optimization methods. Methods Mol Biol (2008) 0.89
The role of the p75 neurotrophin receptor in cholinergic dysfunction in Alzheimer's disease. Neuroscientist (2009) 0.89
IL8 and CXCL13 are potent chemokines for the recruitment of human neural precursor cells across brain endothelial cells. J Neuroimmunol (2010) 0.89
Signaling of the neurotrophin receptor p75 in relation to Alzheimer's disease. Biochem Biophys Res Commun (2009) 0.89
Neurotrophins: from pathophysiology to treatment in Alzheimer's disease. Curr Alzheimer Res (2008) 0.88
apolipoprotein-E dependent role for the FAS receptor in early onset Alzheimer's disease: finding of a positive association for a polymorphism in the TNFRSF6 gene. Hum Genet (2000) 0.88
Increased cerebrospinal fluid levels of neurotrophin 3 (NT-3) in elderly patients with major depression. Mol Psychiatry (2000) 0.87
Distinguishing childhood absence epilepsy patients from controls by the analysis of their background brain electrical activity (II): a combinatorial optimization approach for electrode selection. J Neurosci Methods (2009) 0.87
Alzheimer-associated neuronal thread protein-induced apoptosis and impaired mitochondrial function in human central nervous system-derived neuronal cells. J Neuropathol Exp Neurol (2001) 0.85
Expression and production of two selected beta-chemokines in peripheral blood mononuclear cells from patients with Alzheimer's disease. Exp Gerontol (2005) 0.84
p75 reduces beta-amyloid-induced sympathetic innervation deficits in an Alzheimer's disease mouse model. Proc Natl Acad Sci U S A (2009) 0.83
Fas antigen and sporadic Alzheimer's disease in Southern Italy: evaluation of two polymorphisms in the TNFRSF6 gene. Neurochem Res (2007) 0.83
Roles of platelet-derived growth factor-B expression in the ventral horn and motor cortex in the spinal cord-hemisected rhesus monkey. J Neurotrauma (2009) 0.80
Increased serum levels of CD95 in Alzheimer's disease. Dement Geriatr Cogn Disord (2002) 0.79
Polymorphisms of fas gene: relationship with Alzheimer's disease and cognitive decline. Dement Geriatr Cogn Disord (2006) 0.79
Association between APOE epsilon4 allele and increased expression of CD95 on T cells from patients with Alzheimer's disease. Methods Find Exp Clin Pharmacol (2004) 0.79
Further evidence for role of a promoter variant in the TNFRSF6 gene in Alzheimer disease. Hum Mutat (2003) 0.78
The Fas gene A-670G polymorphism is not associated with sporadic Alzheimer disease in a Chinese Han population. Brain Res (2006) 0.78
The Fas promoter polymorphism at position -670 is not associated with late-onset sporadic Alzheimer's disease. Dement Geriatr Cogn Disord (2004) 0.78
Apolipoprotein E epsilon 4 is associated with an increased vulnerability to cell death in Alzheimer's disease. J Neural Transm (Vienna) (2006) 0.77
Fas and activated caspase 8 in normal, Alzheimer and multiple infarct brains. Neurosci Lett (2004) 0.77
Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. Ann Neurol (2011) 3.52
Genome-wide analysis of long noncoding RNA stability. Genome Res (2012) 2.49
Common variants at 6p21.1 are associated with large artery atherosclerotic stroke. Nat Genet (2012) 1.81
The multiple sclerosis whole blood mRNA transcriptome and genetic associations indicate dysregulation of specific T cell pathways in pathogenesis. Hum Mol Genet (2010) 1.73
Multivariate protein signatures of pre-clinical Alzheimer's disease in the Alzheimer's disease neuroimaging initiative (ADNI) plasma proteome dataset. PLoS One (2012) 1.51
Uncovering molecular biomarkers that correlate cognitive decline with the changes of hippocampus' gene expression profiles in Alzheimer's disease. PLoS One (2010) 1.41
Identification of a 5-protein biomarker molecular signature for predicting Alzheimer's disease. PLoS One (2008) 1.31
Cancer biomarker discovery: the entropic hallmark. PLoS One (2010) 1.26
Language Individuation and Marker Words: Shakespeare and His Maxwell's Demon. PLoS One (2013) 1.25
Is there more than one proctitis syndrome? A revisitation using data from the TROG 96.01 trial. Radiother Oncol (2008) 1.20
Combinatorial optimization models for finding genetic signatures from gene expression datasets. Methods Mol Biol (2008) 1.19
Unveiling clusters of RNA transcript pairs associated with markers of Alzheimer's disease progression. PLoS One (2012) 1.18
GPU-FS-kNN: a software tool for fast and scalable kNN computation using GPUs. PLoS One (2012) 1.15
Microarrays--identifying molecular portraits for prostate tumors with different Gleason patterns. Methods Mol Med (2008) 1.05
A transcription factor map as revealed by a genome-wide gene expression analysis of whole-blood mRNA transcriptome in multiple sclerosis. PLoS One (2010) 1.00
QAPgrid: a two level QAP-based approach for large-scale data analysis and visualization. PLoS One (2011) 0.92
Are myocardial infarction--associated single-nucleotide polymorphisms associated with ischemic stroke? Stroke (2012) 0.91
A memetic-aided approach to hierarchical clustering from distance matrices: application to gene expression clustering and phylogeny. Biosystems (2003) 0.90
Genetic signatures for a rodent model of Parkinson's disease using combinatorial optimization methods. Methods Mol Biol (2008) 0.89
'Neuroinflammation' differs categorically from inflammation: transcriptomes of Alzheimer's disease, Parkinson's disease, schizophrenia and inflammatory diseases compared. Neurogenetics (2014) 0.88
Distinguishing childhood absence epilepsy patients from controls by the analysis of their background brain electrical activity (II): a combinatorial optimization approach for electrode selection. J Neurosci Methods (2009) 0.87
Sifting the wheat from the chaff: prioritizing GWAS results by identifying consistency across analytical methods. Genet Epidemiol (2011) 0.85
Brain transcriptome perturbations in the Hfe(-/-) mouse model of genetic iron loading. Brain Res (2012) 0.83
Distinguishing childhood absence epilepsy patients from controls by the analysis of their background brain electrical activity. J Neurosci Methods (2008) 0.81
The Gene Interaction Miner: a new tool for data mining contextual information for protein-protein interaction analysis. Bioinformatics (2009) 0.78
A kernelisation approach for multiple d-Hitting Set and its application in optimal multi-drug therapeutic combinations. PLoS One (2010) 0.77
Changes in brain transcripts related to Alzheimer's disease in a model of HFE hemochromatosis are not consistent with increased Alzheimer's disease risk. J Alzheimers Dis (2012) 0.76
Hierarchical clustering using the arithmetic-harmonic cut: complexity and experiments. PLoS One (2010) 0.75