Published in PLoS One on April 19, 2011
Specific soluble oligomers of amyloid-β peptide undergo replication and form non-fibrillar aggregates in interfacial environments. J Biol Chem (2012) 0.89
Proteolytically inactive insulin-degrading enzyme inhibits amyloid formation yielding non-neurotoxic aβ peptide aggregates. PLoS One (2013) 0.87
Gadd153 and NF-κB crosstalk regulates 27-hydroxycholesterol-induced increase in BACE1 and β-amyloid production in human neuroblastoma SH-SY5Y cells. PLoS One (2013) 0.87
Dopamine-induced α-synuclein oligomers show self- and cross-propagation properties. Protein Sci (2014) 0.85
Self-propagative replication of Aβ oligomers suggests potential transmissibility in Alzheimer disease. PLoS One (2014) 0.81
Amyloid β Oligomeric Species Present in the Lag Phase of Amyloid Formation. PLoS One (2015) 0.79
Conformational Dynamics of Specific Aβ Oligomers Govern Their Ability To Replicate and Induce Neuronal Apoptosis. Biochemistry (2016) 0.78
Determination of critical nucleation number for a single nucleation amyloid-β aggregation model. Math Biosci (2016) 0.78
Strain-specific Fibril Propagation by an Aβ Dodecamer. Sci Rep (2017) 0.77
The natural product betulinic acid rapidly promotes amyloid-β fibril formation at the expense of soluble oligomers. ACS Chem Neurosci (2012) 0.75
Protein folding, misfolding and aggregation: The importance of two-electron stabilizing interactions. PLoS One (2017) 0.75
Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice. Science (1996) 19.72
Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo. Nature (2002) 19.36
A specific amyloid-beta protein assembly in the brain impairs memory. Nature (2006) 16.19
Physical basis of cognitive alterations in Alzheimer's disease: synapse loss is the major correlate of cognitive impairment. Ann Neurol (1991) 14.25
Alzheimer's disease: the amyloid cascade hypothesis. Science (1992) 13.80
Seeding "one-dimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie? Cell (1993) 10.15
Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease. Ann Neurol (1999) 7.69
Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease. Am J Pathol (1999) 7.16
Generating a prion with bacterially expressed recombinant prion protein. Science (2010) 6.26
On the nucleation and growth of amyloid beta-protein fibrils: detection of nuclei and quantitation of rate constants. Proc Natl Acad Sci U S A (1996) 4.75
Effect of environmental factors on the kinetics of insulin fibril formation: elucidation of the molecular mechanism. Biochemistry (2001) 3.47
Small molecule inhibitors of aggregation indicate that amyloid beta oligomerization and fibrillization pathways are independent and distinct. J Biol Chem (2007) 3.42
Globular amyloid beta-peptide oligomer - a homogenous and stable neuropathological protein in Alzheimer's disease. J Neurochem (2005) 3.06
Seeding specificity in amyloid growth induced by heterologous fibrils. J Biol Chem (2004) 2.35
Apolipoprotein E is a kinetic but not a thermodynamic inhibitor of amyloid formation: implications for the pathogenesis and treatment of Alzheimer disease. Proc Natl Acad Sci U S A (1995) 2.11
Ionization and phase behavior of fatty acids in water: application of the Gibbs phase rule. Biochemistry (1988) 1.94
Dimeric amyloid beta protein rapidly accumulates in lipid rafts followed by apolipoprotein E and phosphorylated tau accumulation in the Tg2576 mouse model of Alzheimer's disease. J Neurosci (2004) 1.92
Correlations of synaptic and pathological markers with cognition of the elderly. Neurobiol Aging (1995) 1.90
Interaction of Alzheimer beta-amyloid peptide(1-40) with lipid membranes. Biochemistry (1997) 1.71
Structure and polymorphism in lipid-water systems, and their possible biological implications. Ann N Y Acad Sci (1966) 1.71
Two types of Alzheimer's beta-amyloid (1-40) peptide membrane interactions: aggregation preventing transmembrane anchoring versus accelerated surface fibril formation. J Mol Biol (2004) 1.62
Lipid interaction converts prion protein to a PrPSc-like proteinase K-resistant conformation under physiological conditions. Biochemistry (2007) 1.62
Granulins: the structure and function of an emerging family of growth factors. J Endocrinol (1998) 1.57
Self-association of beta-amyloid peptide (1-40) in solution and binding to lipid membranes. J Mol Biol (1995) 1.57
Interactions of amyloid beta-protein with various gangliosides in raft-like membranes: importance of GM1 ganglioside-bound form as an endogenous seed for Alzheimer amyloid. Biochemistry (2002) 1.56
Selective inhibition of Abeta fibril formation. J Biol Chem (1996) 1.53
Physical, morphological and functional differences between ph 5.8 and 7.4 aggregates of the Alzheimer's amyloid peptide Abeta. J Mol Biol (1996) 1.45
A seed for Alzheimer amyloid in the brain. J Neurosci (2004) 1.45
Interaction between A beta(1-42) and A beta(1-40) in Alzheimer's beta-amyloid fibril formation in vitro. Biochemistry (1999) 1.40
Low concentrations of sodium dodecyl sulfate induce the extension of beta 2-microglobulin-related amyloid fibrils at a neutral pH. Biochemistry (2004) 1.39
Formation of amyloid fibers triggered by phosphatidylserine-containing membranes. Biochemistry (2004) 1.38
Amyloid-beta peptide assembly: a critical step in fibrillogenesis and membrane disruption. Biophys J (2001) 1.37
Acceleration of amyloid fibril formation by specific binding of Abeta-(1-40) peptide to ganglioside-containing membrane vesicles. J Biol Chem (1997) 1.35
A topological model of the interaction between alpha-synuclein and sodium dodecyl sulfate micelles. Biochemistry (2005) 1.33
Abeta-globulomers are formed independently of the fibril pathway. Neurobiol Dis (2008) 1.23
Docosahexaenoic acid and the aging brain. J Nutr (2008) 1.20
Interactions of amyloid beta-peptide (1-40) with ganglioside-containing membranes. Biochemistry (1999) 1.14
The interaction between Alzheimer amyloid beta(1-40) peptide and ganglioside GM1-containing membranes. FEBS Lett (1997) 1.13
Amyloid-beta(1-42) rapidly forms protofibrils and oligomers by distinct pathways in low concentrations of sodium dodecylsulfate. Biochemistry (2007) 1.13
Rifampicin prevents the aggregation and neurotoxicity of amyloid beta protein in vitro. Biochem Biophys Res Commun (1994) 1.12
Design of peptide-based inhibitors of human islet amyloid polypeptide fibrillogenesis. J Mol Biol (2002) 1.11
Polyunsaturated fatty acids induce alpha-synuclein-related pathogenic changes in neuronal cells. Am J Pathol (2007) 1.08
Amyloid beta oligomerization is induced by brain lipid rafts. J Cell Biochem (2006) 1.07
Fusogenic properties of the C-terminal domain of the Alzheimer beta-amyloid peptide. J Biol Chem (1996) 1.06
Structures of beta-amyloid peptide 1-40, 1-42, and 1-55-the 672-726 fragment of APP-in a membrane environment with implications for interactions with gamma-secretase. J Am Chem Soc (2009) 0.98
Aggregation of liposomes induced by the toxic peptides Alzheimer's Abetas, human amylin and prion (106-126): facilitation by membrane-bound GM1 ganglioside. Peptides (2004) 0.97
Secondary structure and interfacial aggregation of amyloid-beta(1-40) on sodium dodecyl sulfate micelles. Biochemistry (2006) 0.97
Fluorescence detection of a lipid-induced tetrameric intermediate in amyloid fibril formation by apolipoprotein C-II. J Biol Chem (2008) 0.96
Assembly of hereditary amyloid beta-protein variants in the presence of favorable gangliosides. FEBS Lett (2005) 0.95
GM1 ganglioside-mediated accumulation of amyloid beta-protein on cell membranes. Biochem Biophys Res Commun (2005) 0.94
GM1 ganglioside and the seeding of amyloid in Alzheimer's disease: endogenous seed for Alzheimer amyloid. Neuroscientist (2005) 0.94
Dietary fatty acids in dementia and predementia syndromes: epidemiological evidence and possible underlying mechanisms. Ageing Res Rev (2009) 0.92
Environment- and mutation-dependent aggregation behavior of Alzheimer amyloid beta-protein. J Neurochem (2004) 0.91
The interaction of beta-amyloid protein fragment (12-28) with lipid environments. Protein Sci (1997) 0.88
GM1 ganglioside-bound amyloid beta-protein in Alzheimer's disease brain. Neurobiol Aging (1998) 0.88
Interactions between fatty acids and alpha-synuclein. J Lipid Res (2006) 0.88
Aggregation of beta(2)-glycoprotein I induced by sodium lauryl sulfate and lysophospholipids. Biochemistry (2002) 0.86
Rapid assembly of amyloid-beta peptide at a liquid/liquid interface produces unstable beta-sheet fibers. Biochemistry (2005) 0.86
Alzheimer's disease amyloid beta peptide 25-35 inhibits lipid peroxidation as a result of its membrane interactions. Biochem Biophys Res Commun (1997) 0.85
Growth of beta(2)-microglobulin-related amyloid fibrils by non-esterified fatty acids at a neutral pH. Biochem J (2008) 0.84
Interactions between fatty acids and lipoprotein lipase: specific binding and complex formation. Biochemistry (1994) 0.82
Identification of short-chain oxidized phosphatidylcholine in human plasma. J Lipid Res (1996) 0.80
Accelerated Abeta aggregation in the presence of GM1-ganglioside-accumulated synaptosomes of aged apoE4-knock-in mouse brain. FEBS Lett (2004) 0.80
Intravenous lipid emulsions to deliver omega 3 fatty acids. Prostaglandins Leukot Essent Fatty Acids (2006) 0.79
Interactions of Abeta(1-40) with glycerophosphocholine and intact erythrocyte membranes: fluorescence and circular dichroism studies. Neurochem Res (2004) 0.76
Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity. Proc Natl Acad Sci U S A (2009) 3.65
Substrate-targeting gamma-secretase modulators. Nature (2008) 3.38
Accumulation of pathological tau species and memory loss in a conditional model of tauopathy. J Neurosci (2007) 2.55
BRI2 (ITM2b) inhibits Abeta deposition in vivo. J Neurosci (2008) 1.62
Biophysical analyses of synthetic amyloid-beta(1-42) aggregates before and after covalent cross-linking. Implications for deducing the structure of endogenous amyloid-beta oligomers. Biochemistry (2009) 0.99
The regulation of N-methyl-D-aspartate receptors by Src kinase. FEBS J (2011) 0.98
Dynamics of protofibril elongation and association involved in Aβ42 peptide aggregation in Alzheimer's disease. BMC Bioinformatics (2010) 0.98
Structure of the flexible amino-terminal domain of prion protein bound to a sulfated glycan. J Mol Biol (2009) 0.91
Facilitated cross-bridge interactions with thin filaments by familial hypertrophic cardiomyopathy mutations in α-tropomyosin. J Biomed Biotechnol (2011) 0.90
Bile acid and sterol metabolism with combined HMG-CoA reductase and PCSK9 suppression. J Lipid Res (2013) 0.90
Specific soluble oligomers of amyloid-β peptide undergo replication and form non-fibrillar aggregates in interfacial environments. J Biol Chem (2012) 0.89
Prolylpeptide binding by the prokaryotic SH3-like domain of the diphtheria toxin repressor: a regulatory switch. Biochemistry (2005) 0.89
Allele-specific germ cell epimutation in the spacer promoter of the 45S ribosomal RNA gene after Cr(III) exposure. Toxicol Appl Pharmacol (2004) 0.88
Sequence of ligand binding and structure change in the diphtheria toxin repressor upon activation by divalent transition metals. Biochemistry (2005) 0.88
Receptors and lytic mediators regulating anti-tumor activity by the leukemic killer T cell line TALL-104. J Leukoc Biol (2005) 0.86
Dopamine-induced α-synuclein oligomers show self- and cross-propagation properties. Protein Sci (2014) 0.85
The Balanced Budget Act of 1997 and the financial health of teaching hospitals. Ann Fam Med (2004) 0.83
Immunoinformatic evaluation of multiple epitope ensembles as vaccine candidates: E coli 536. Bioinformation (2012) 0.82
Antimicrobial poly(methacrylamide) derivatives prepared via aqueous RAFT polymerization exhibit biocidal efficiency dependent upon cation structure. Biomacromolecules (2012) 0.82
Ethanol potentiates HIV-1 gp120-induced apoptosis in human neurons via both the death receptor and NMDA receptor pathways. Virology (2005) 0.81
Characterization of neuronal Src kinase purified from a bacterial expression system. Protein Expr Purif (2010) 0.81
Smooth muscle titin Zq domain interaction with the smooth muscle alpha-actinin central rod. J Biol Chem (2008) 0.78
Roles of the SH2 and SH3 domains in the regulation of neuronal Src kinase functions. FEBS J (2010) 0.77
A modified Stokes-Einstein equation for Aβ aggregation. BMC Bioinformatics (2011) 0.77
Inhibition of Aβ42 peptide aggregation by a binuclear ruthenium(II)-platinum(II) complex: Potential for multi-metal organometallics as anti-amyloid agents. ACS Chem Neurosci (2010) 0.77
Kinetics and control of self-assembly of ABH1 hydrophobin from the edible white button mushroom. Biomacromolecules (2013) 0.76
The natural product betulinic acid rapidly promotes amyloid-β fibril formation at the expense of soluble oligomers. ACS Chem Neurosci (2012) 0.75
Nanoscale reduction in surface friction of polymer surfaces modified with Sc3 hydrophobin from Schizophyllum commune. Biomacromolecules (2006) 0.75
Fulminant meningococcal sepsis: localized outbreak of three patients treated with therapeutic plasma exchange by membrane filtration. Blood Purif (2010) 0.75
Body MR Imaging: Artifacts, k-Space, and Solutions-Erratum. Radiographics (2015) 0.75
After the injury. Am J Med (2007) 0.75
Thermal control of nanostructure and molecular network development in epoxy-amine thermosets. ACS Appl Mater Interfaces (2012) 0.75
Polypeptide-catalyzed silica for dental applications. J Biomed Mater Res B Appl Biomater (2009) 0.75
Aqueous RAFT Synthesis of Glycopolymers for Determination of Saccharide Structure and Concentration Effects on Amyloid β Aggregation. Biomacromolecules (2017) 0.75
POSS-enhanced phase separation in air-processed P3HT:PCBM bulk heterojunction photovoltaic systems. ACS Appl Mater Interfaces (2013) 0.75
Treatment of severe tetanus with intrathecal baclofen via implantable infusion device: a case report. Neuromodulation (2014) 0.75
PARENTERAL DRUG ASSOCIATION POINTS TO CONSIDER: Pharmaceutical Quality Metrics Updated September 2014. PDA J Pharm Sci Technol (2014) 0.75