PubRank

Shmuel Muallem

Author PubWeight™ 137.18‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 STIM1 carboxyl-terminus activates native SOC, I(crac) and TRPC1 channels. Nat Cell Biol 2006 5.68
2 SOAR and the polybasic STIM1 domains gate and regulate Orai channels. Nat Cell Biol 2009 4.73
3 STIM1 heteromultimerizes TRPC channels to determine their function as store-operated channels. Nat Cell Biol 2007 3.47
4 Gating of CFTR by the STAS domain of SLC26 transporters. Nat Cell Biol 2004 3.43
5 Homer binds TRPC family channels and is required for gating of TRPC1 by IP3 receptors. Cell 2003 3.11
6 STIM1 gates TRPC channels, but not Orai1, by electrostatic interaction. Mol Cell 2008 2.30
7 A molecular mechanism for aberrant CFTR-dependent HCO(3)(-) transport in cystic fibrosis. EMBO J 2002 2.11
8 TRPC channels as STIM1-regulated store-operated channels. Cell Calcium 2007 2.04
9 NaBC1 is a ubiquitous electrogenic Na+ -coupled borate transporter essential for cellular boron homeostasis and cell growth and proliferation. Mol Cell 2004 2.02
10 TRP-ML1 regulates lysosomal pH and acidic lysosomal lipid hydrolytic activity. J Biol Chem 2005 1.96
11 Transporter-mediated bile acid uptake causes Ca2+-dependent cell death in rat pancreatic acinar cells. Gastroenterology 2002 1.91
12 Corticosteroids correct aberrant CFTR localization in the duct and regenerate acinar cells in autoimmune pancreatitis. Gastroenterology 2010 1.86
13 The solute carrier 26 family of proteins in epithelial ion transport. Physiology (Bethesda) 2008 1.76
14 TRP-ML1 is a lysosomal monovalent cation channel that undergoes proteolytic cleavage. J Biol Chem 2005 1.75
15 Coupling modes and stoichiometry of Cl-/HCO3- exchange by slc26a3 and slc26a6. J Gen Physiol 2006 1.73
16 Protease-activated receptor 2 exerts local protection and mediates some systemic complications in acute pancreatitis. Gastroenterology 2004 1.72
17 Molecular mechanism of pancreatic and salivary gland fluid and HCO3 secretion. Physiol Rev 2012 1.71
18 Hypoxia reprograms calcium signaling and regulates myoglobin expression. Am J Physiol Cell Physiol 2008 1.69
19 RANKL-mediated reactive oxygen species pathway that induces long lasting Ca2+ oscillations essential for osteoclastogenesis. J Biol Chem 2010 1.58
20 Slc26a6 regulates CFTR activity in vivo to determine pancreatic duct HCO3- secretion: relevance to cystic fibrosis. EMBO J 2006 1.56
21 Gain-of-function mutation in TRPML3 causes the mouse Varitint-Waddler phenotype. J Biol Chem 2007 1.56
22 Homer 1 mediates store- and inositol 1,4,5-trisphosphate receptor-dependent translocation and retrieval of TRPC3 to the plasma membrane. J Biol Chem 2006 1.50
23 A novel mode of TRPML3 regulation by extracytosolic pH absent in the varitint-waddler phenotype. EMBO J 2008 1.47
24 Homer proteins in Ca2+ signaling by excitable and non-excitable cells. Cell Calcium 2007 1.45
25 The Ca(2+) channel TRPML3 regulates membrane trafficking and autophagy. Traffic 2009 1.44
26 TRPC channels as STIM1-regulated SOCs. Channels (Austin) 2009 1.43
27 Congenital chloride-losing diarrhea causing mutations in the STAS domain result in misfolding and mistrafficking of SLC26A3. J Biol Chem 2008 1.43
28 Convergent regulation of the lysosomal two-pore channel-2 by Mg²⁺, NAADP, PI(3,5)P₂ and multiple protein kinases. EMBO J 2014 1.43
29 The Slc26a4 transporter functions as an electroneutral Cl-/I-/HCO3- exchanger: role of Slc26a4 and Slc26a6 in I- and HCO3- secretion and in regulation of CFTR in the parotid duct. J Physiol 2008 1.40
30 Mitochondria and calcium in health and disease. Cell Calcium 2008 1.39
31 An endoplasmic reticulum/plasma membrane junction: STIM1/Orai1/TRPCs. FEBS Lett 2009 1.39
32 Molecular determinants of fast Ca2+-dependent inactivation and gating of the Orai channels. Proc Natl Acad Sci U S A 2009 1.38
33 Deletion of TRPC3 in mice reduces store-operated Ca2+ influx and the severity of acute pancreatitis. Gastroenterology 2009 1.37
34 Spinophilin regulates Ca2+ signalling by binding the N-terminal domain of RGS2 and the third intracellular loop of G-protein-coupled receptors. Nat Cell Biol 2005 1.36
35 Diverse transport modes by the solute carrier 26 family of anion transporters. J Physiol 2008 1.35
36 Native Store-operated Ca2+ Influx Requires the Channel Function of Orai1 and TRPC1. J Biol Chem 2009 1.34
37 SLC26A9 is a Cl(-) channel regulated by the WNK kinases. J Physiol 2007 1.33
38 IRBIT coordinates epithelial fluid and HCO3- secretion by stimulating the transporters pNBC1 and CFTR in the murine pancreatic duct. J Clin Invest 2008 1.32
39 Transient receptor potential mucolipin 1 (TRPML1) and two-pore channels are functionally independent organellar ion channels. J Biol Chem 2011 1.32
40 Aberrant localization of intracellular organelles, Ca2+ signaling, and exocytosis in Mist1 null mice. J Biol Chem 2005 1.30
41 Spinophilin/neurabin reciprocally regulate signaling intensity by G protein-coupled receptors. EMBO J 2007 1.29
42 Dynamic control of cystic fibrosis transmembrane conductance regulator Cl(-)/HCO3(-) selectivity by external Cl(-). J Biol Chem 2004 1.28
43 Evolution of calcium homeostasis: from birth of the first cell to an omnipresent signalling system. Cell Calcium 2007 1.26
44 Calcium signaling complexes in microdomains of polarized secretory cells. Cell Calcium 2006 1.24
45 Pancreatitis: the neglected duct. Gut 2008 1.22
46 SLC26A7 is a Cl- channel regulated by intracellular pH. J Biol Chem 2004 1.22
47 Polarized but differential localization and recruitment of STIM1, Orai1 and TRPC channels in secretory cells. Traffic 2010 1.20
48 Homer 2 tunes G protein-coupled receptors stimulus intensity by regulating RGS proteins and PLCbeta GAP activities. J Cell Biol 2003 1.20
49 Signalling specificity in GPCR-dependent Ca2+ signalling. Cell Signal 2003 1.19
50 IRBIT governs epithelial secretion in mice by antagonizing the WNK/SPAK kinase pathway. J Clin Invest 2011 1.18
51 Reactive oxygen species-mediated TRPC6 protein activation in vascular myocytes, a mechanism for vasoconstrictor-regulated vascular tone. J Biol Chem 2011 1.17
52 Borate transport and cell growth and proliferation. Not only in plants. Cell Cycle 2005 1.15
53 Irbit mediates synergy between ca(2+) and cAMP signaling pathways during epithelial transport in mice. Gastroenterology 2013 1.10
54 AE4 is a DIDS-sensitive Cl(-)/HCO(-)(3) exchanger in the basolateral membrane of the renal CCD and the SMG duct. Am J Physiol Cell Physiol 2002 1.10
55 A new mode of Ca2+ signaling by G protein-coupled receptors: gating of IP3 receptor Ca2+ release channels by Gbetagamma. Curr Biol 2003 1.08
56 The STIM1 CTID domain determines access of SARAF to SOAR to regulate Orai1 channel function. J Cell Biol 2013 1.07
57 The cystic fibrosis transmembrane conductance regulator interacts with and regulates the activity of the HCO3- salvage transporter human Na+-HCO3- cotransport isoform 3. J Biol Chem 2002 1.06
58 Determinants of coupled transport and uncoupled current by the electrogenic SLC26 transporters. J Gen Physiol 2011 1.05
59 Regulatory interaction between CFTR and the SLC26 transporters. Novartis Found Symp 2006 1.04
60 Membrane potential regulates nicotinic acid adenine dinucleotide phosphate (NAADP) dependence of the pH- and Ca2+-sensitive organellar two-pore channel TPC1. J Biol Chem 2012 1.04
61 TRPpathies. J Physiol 2006 1.04
62 STIM1-dependent and STIM1-independent function of transient receptor potential canonical (TRPC) channels tunes their store-operated mode. J Biol Chem 2010 1.03
63 Genetic and pharmacologic inhibition of the Ca2+ influx channel TRPC3 protects secretory epithelia from Ca2+-dependent toxicity. Gastroenterology 2011 1.02
64 A role for the Ca2+ channel TRPML1 in gastric acid secretion, based on analysis of knockout mice. Gastroenterology 2010 1.01
65 Acidic Ca(2+) stores come to the fore. Cell Calcium 2011 1.00
66 ER stress disrupts Ca2+-signaling complexes and Ca2+ regulation in secretory and muscle cells from PERK-knockout mice. J Cell Sci 2005 0.98
67 Cell-specific behavior of P2X7 receptors in mouse parotid acinar and duct cells. J Biol Chem 2003 0.97
68 Protein-protein interaction and functionTRPC channels. Pflugers Arch 2005 0.97
69 Convergence of IRBIT, phosphatidylinositol (4,5) bisphosphate, and WNK/SPAK kinases in regulation of the Na+-HCO3- cotransporters family. Proc Natl Acad Sci U S A 2013 0.97
70 Selective Gαi subunits as novel direct activators of transient receptor potential canonical (TRPC)4 and TRPC5 channels. J Biol Chem 2012 0.97
71 Multiple effects of SERCA2b mutations associated with Darier's disease. J Biol Chem 2003 0.97
72 Peptidyl-prolyl isomerase FKBP52 controls chemotropic guidance of neuronal growth cones via regulation of TRPC1 channel opening. Neuron 2009 0.96
73 Ca2+ signaling in microdomains: Homer1 mediates the interaction between RyR2 and Cav1.2 to regulate excitation-contraction coupling. J Biol Chem 2007 0.94
74 The WNK/SPAK and IRBIT/PP1 pathways in epithelial fluid and electrolyte transport. Physiology (Bethesda) 2012 0.94
75 Molecular determinants mediating gating of Transient Receptor Potential Canonical (TRPC) channels by stromal interaction molecule 1 (STIM1). J Biol Chem 2014 0.93
76 The intracellular Ca²⁺ channels of membrane traffic. Channels (Austin) 2012 0.93
77 Properties of the TRPML3 channel pore and its stable expansion by the Varitint-Waddler-causing mutation. J Biol Chem 2010 0.92
78 Role of regulator of G protein signaling 2 (RGS2) in Ca(2+) oscillations and adaptation of Ca(2+) signaling to reduce excitability of RGS2-/- cells. J Biol Chem 2004 0.91
79 Aberrant Ca2+ handling in lysosomal storage disorders. Cell Calcium 2010 0.91
80 Regulation of the P2X7 receptor permeability to large molecules by extracellular Cl- and Na+. J Biol Chem 2005 0.90
81 TRPML: transporters of metals in lysosomes essential for cell survival? Cell Calcium 2011 0.88
82 IRBIT: it is everywhere. Neurochem Res 2010 0.88
83 Serine-threonine kinase with-no-lysine 4 (WNK4) controls blood pressure via transient receptor potential canonical 3 (TRPC3) in the vasculature. Proc Natl Acad Sci U S A 2011 0.87
84 Skeletal muscle dressed in SOCs. Nat Cell Biol 2008 0.86
85 Solute carrier family 26 member a2 (Slc26a2) protein functions as an electroneutral SOFormula/OH-/Cl- exchanger regulated by extracellular Cl-. J Biol Chem 2011 0.85
86 The gatekeepers of mitochondrial calcium influx: MICU1 and MICU2. EMBO Rep 2014 0.85
87 SLC26A6 and NaDC-1 transporters interact to regulate oxalate and citrate homeostasis. J Am Soc Nephrol 2013 0.85
88 Analyses of RGS protein control of agonist-evoked Ca2+ signaling. Methods Enzymol 2004 0.84
89 Mitochondrial Ca2+ homeostasis in lysosomal storage diseases. Cell Calcium 2008 0.84
90 The TRPCs-STIM1-Orai interaction. Handb Exp Pharmacol 2014 0.84
91 Functional mapping of Ca2+ signaling complexes in plasma membrane microdomains of polarized cells. J Biol Chem 2004 0.82
92 Ca(2+) signalling and gene regulation. Cell Calcium 2011 0.81
93 SLC26A7 can function as a chloride-loading mechanism in parietal cells. Pflugers Arch 2007 0.81
94 Ca2+ signaling in polarized exocrine cells. Adv Exp Med Biol 2002 0.80
95 Unlocking SOAR releases STIM. EMBO J 2011 0.80
96 Mechanism and synergism in epithelial fluid and electrolyte secretion. Pflugers Arch 2013 0.80
97 Subpopulation of store-operated Ca2+ channels regulate Ca2+-induced Ca2+ release in non-excitable cells. J Biol Chem 2004 0.79
98 Aquaporin 1 water channel is overexpressed in the plasma membranes of pancreatic ducts in patients with autoimmune pancreatitis. J Med Invest 2009 0.78
99 Markers of squamous cell carcinoma in sarco/endoplasmic reticulum Ca2+ ATPase 2 heterozygote mice keratinocytes. Prog Biophys Mol Biol 2009 0.78
100 Multiple roles of the SO4(2-)/Cl-/OH- exchanger protein Slc26a2 in chondrocyte functions. J Biol Chem 2013 0.77
101 What the mitochondria see. Mol Cell 2010 0.77
102 Lipids in Ca2+ signalling--an introduction. Cell Calcium 2009 0.77
103 Opening the TRPML gates. Chem Biol 2010 0.77
104 The α2B-adrenergic receptor is mutant in cortical myoclonus and epilepsy. Ann Neurol 2014 0.76
105 The art of physiology in the hands of the master: the calcium community celebrates the 70th birthday of Ole Holger Petersen. Cell Calcium 2013 0.76
106 Cloning, expression and functional characterization of the putative regeneration and tolerance factor (RTF/TJ6) as a functional vacuolar ATPase proton pump regulatory subunit with a conserved sequence of immunoreceptor tyrosine-based activation motif. Int Immunol 2005 0.76