Published in Cell on February 09, 1990
Prohibitin, an evolutionarily conserved intracellular protein that blocks DNA synthesis in normal fibroblasts and HeLa cells. Mol Cell Biol (1991) 2.04
Mouse beta-globin DNA-binding protein B1 is identical to a proto-oncogene, the transcription factor Spi-1/PU.1, and is restricted in expression to hematopoietic cells and the testis. Mol Cell Biol (1993) 1.80
Constitutional 1p36 deletion in a child with neuroblastoma. Am J Hum Genet (1993) 1.75
Increased expression of the insulin-like growth factor I receptor gene, IGF1R, in Wilms tumor is correlated with modulation of IGF1R promoter activity by the WT1 Wilms tumor gene product. Proc Natl Acad Sci U S A (1993) 1.59
Mutations in the ZNF41 gene are associated with cognitive deficits: identification of a new candidate for X-linked mental retardation. Am J Hum Genet (2003) 1.52
Human platelet-derived growth factor A chain is transcriptionally repressed by the Wilms tumor suppressor WT1. Proc Natl Acad Sci U S A (1992) 1.51
Complete sequencing of the Fugu WAGR region from WT1 to PAX6: dramatic compaction and conservation of synteny with human chromosome 11p13. Proc Natl Acad Sci U S A (1998) 1.31
Paired box mutations in familial and sporadic aniridia predicts truncated aniridia proteins. Am J Hum Genet (1994) 1.29
Sequence and structural requirements for high-affinity DNA binding by the WT1 gene product. Mol Cell Biol (1995) 1.27
Zinc finger point mutations within the WT1 gene in Wilms tumor patients. Proc Natl Acad Sci U S A (1992) 1.26
Establishment of a highly sensitive and specific exon-trapping system. Proc Natl Acad Sci U S A (1992) 1.17
Role of EGR-1 in thapsigargin-inducible apoptosis in the melanoma cell line A375-C6. Mol Cell Biol (1995) 1.13
Loss of constitutional heterozygosity on chromosome 5q in hepatocellular carcinoma without cirrhosis. Br J Cancer (1991) 1.10
Genome-wide search for loss of heterozygosity in transgenic mouse tumors reveals candidate tumor suppressor genes on chromosomes 9 and 16. Proc Natl Acad Sci U S A (1994) 1.02
Inhibition of cellular proliferation by the Wilms' tumor suppressor WT1 is associated with suppression of insulin-like growth factor I receptor gene expression. Mol Cell Biol (1995) 1.00
Expression of the 11p13 Wilms' tumor gene, WT1, correlates with histologic category of Wilms' tumor. Am J Pathol (1992) 0.98
Chromosomal localisation of two putative 11p oncosuppressor genes involved in human ovarian tumours. Br J Cancer (1992) 0.97
Integration of Cistromic and Transcriptomic Analyses Identifies Nphs2, Mafb, and Magi2 as Wilms' Tumor 1 Target Genes in Podocyte Differentiation and Maintenance. J Am Soc Nephrol (2015) 0.95
Multiple mechanisms of MYCN dysregulation in Wilms tumour. Oncotarget (2015) 0.91
Neonatal tumours. Pediatr Surg Int (2010) 0.89
Evaluation of current cancer immunotherapy: hemato-oncology. Cancer J (2011) 0.88
A t(4;22) in a meningioma points to the localization of a putative tumor-suppressor gene. Am J Hum Genet (1991) 0.88
Educational paper: the podocytopathies. Eur J Pediatr (2012) 0.88
Clone pAT 133 identifies a gene that encodes another human member of a class of growth factor-induced genes with almost identical zinc-finger domains. Proc Natl Acad Sci U S A (1991) 0.88
Nuclear accumulation of beta-catenin protein indicates activation of wnt signaling in chemically induced rat nephroblastomas. Pediatr Dev Pathol (2010) 0.87
The zinc finger transcription factor EGR-1 impedes interleukin-1-inducible tumor growth arrest. Mol Cell Biol (1995) 0.86
A genome-wide association study identifies four novel susceptibility loci underlying inguinal hernia. Nat Commun (2015) 0.85
Clinical and molecular characterization of patients with heterozygous mutations in wilms tumor suppressor gene 1. Clin J Am Soc Nephrol (2015) 0.84
Distinctive properties of an anaplastic Wilms' tumor and its associated epithelial cell line. Am J Pathol (1994) 0.83
Morphology and growth characteristics of epithelial cells from classic Wilms' tumors. Am J Pathol (1993) 0.80
Deficiency of 5'-deoxy-5'-methylthioadenosine phosphorylase activity in malignancy. Absence of the protein in human enzyme-deficient cell lines. Biochem J (1992) 0.79
Tumour suppression associated with expression of human insulin-like growth factor II. Br J Cancer (1991) 0.79
Characterization of the rat vasoactive intestinal polypeptide receptor gene 5' region. Biochem J (1995) 0.78
Towards an understanding of Wilms' tumour. Int J Exp Pathol (1994) 0.75
Genetics of Obesity. Indian J Clin Biochem (2015) 0.75
Linkage mapping of the human CSF2 and IL3 genes. Proc Natl Acad Sci U S A (1991) 0.75
Mouse chromosome 2. Mamm Genome (1991) 0.75
Wilms tumor arising in a child with X-linked nephrogenic diabetes insipidus. Pediatr Nephrol (2009) 0.75
A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature (1994) 21.59
T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV. Nature (1985) 21.57
Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome. Nat Genet (1997) 10.71
The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis. Dev Cell (2001) 10.33
Movement of Bax from the cytosol to mitochondria during apoptosis. J Cell Biol (1997) 9.18
The Mouse Genome Database (MGD): integrating biology with the genome. Nucleic Acids Res (2004) 8.91
A physical map of the Escherichia coli K12 genome. Science (1987) 8.42
Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus. Cell (1990) 8.30
The Mouse Genome Database (MGD): from genes to mice--a community resource for mouse biology. Nucleic Acids Res (2005) 8.19
Purification, specific fragmentation, and separation of large DNA molecules. Methods Enzymol (1987) 7.40
Nuclear membrane dynamics and reassembly in living cells: targeting of an inner nuclear membrane protein in interphase and mitosis. J Cell Biol (1997) 6.57
Isolation and localization of DNA segments from specific human chromosomes. Proc Natl Acad Sci U S A (1980) 5.76
Conformation of the Bax C-terminus regulates subcellular location and cell death. EMBO J (1999) 5.10
Golgi membranes are absorbed into and reemerge from the ER during mitosis. Cell (1999) 4.79
Diffusional mobility of Golgi proteins in membranes of living cells. Science (1996) 4.73
Characterization of an antigenic determinant of the glycoprotein that correlates with pathogenicity of rabies virus. Proc Natl Acad Sci U S A (1983) 4.54
Case definitions, diagnostic algorithms, and priorities in encephalitis: consensus statement of the international encephalitis consortium. Clin Infect Dis (2013) 4.51
Determination of ligand-binding specificity by alternative splicing: two distinct growth factor receptors encoded by a single gene. Proc Natl Acad Sci U S A (1992) 4.50
Human red cell peptidases. Nature (1967) 4.46
Detection of an unstable fragment of DNA specific to individuals with myotonic dystrophy. Nature (1992) 4.44
A primary genetic map of markers of human chromosome 10. Genomics (1988) 4.23
Parameters governing the transfer of the genes for thymidine kinase and dihydrofolate reductase into mouse cells using metaphase chromosomes or DNA. Somatic Cell Genet (1980) 4.16
Adverse drug reactions-a matter of opinion. Clin Pharmacol Ther (1976) 4.07
Construction of a Not I restriction map of the fission yeast Schizosaccharomyces pombe genome. Nucleic Acids Res (1989) 3.95
Content and organization of the human Ig VH locus: definition of three new VH families and linkage to the Ig CH locus. EMBO J (1988) 3.82
Phase III trial comparing whole-pelvic versus prostate-only radiotherapy and neoadjuvant versus adjuvant combined androgen suppression: Radiation Therapy Oncology Group 9413. J Clin Oncol (2003) 3.73
Localization of the structural gene for human apolipoprotein A-I on the long arm of human chromosome 11. Proc Natl Acad Sci U S A (1984) 3.70
An electrophoretic karyotype for Schizosaccharomyces pombe by pulsed field gel electrophoresis. Nucleic Acids Res (1987) 3.59
Decreased levels of the cell-cycle inhibitor p27Kip1 protein: prognostic implications in primary breast cancer. Nat Med (1997) 3.57
Virus-induced neuronal apoptosis blocked by the herpes simplex virus latency-associated transcript. Science (2000) 3.51
Immuno-PCR: very sensitive antigen detection by means of specific antibody-DNA conjugates. Science (1992) 3.49
Identification of the familial cylindromatosis tumour-suppressor gene. Nat Genet (2000) 3.42
Analysis of cDNA clones specific for human T cells and the alpha and beta chains of the T-cell receptor heterodimer from a human T-cell line. Proc Natl Acad Sci U S A (1985) 3.41
Role of the SulB (FtsZ) protein in division inhibition during the SOS response in Escherichia coli: FtsZ stabilizes the inhibitor SulA in maxicells. Proc Natl Acad Sci U S A (1985) 3.31
Inquiry into clinical trial scandal at Canadian research hospital. Nat Med (1998) 3.27
The 26S proteasome is required for estrogen receptor-alpha and coactivator turnover and for efficient estrogen receptor-alpha transactivation. Mol Cell (2000) 3.23
Further changes in differentiation state accompanying the conversion of Chinese hamster cells of fibroblastic form by dibutyryl adenosine cyclic 3':5'-monophosphate and hormones. Proc Natl Acad Sci U S A (1971) 3.23
Identification of a Pax paired domain recognition sequence and evidence for DNA-dependent conformational changes. J Biol Chem (1994) 3.22
Bax and Bak coalesce into novel mitochondria-associated clusters during apoptosis. J Cell Biol (2001) 3.09
Microsatellite libraries enriched for several microsatellite sequences in plants. Biotechniques (1996) 3.08
Math5 is required for retinal ganglion cell and optic nerve formation. Development (2001) 3.07
Precise localization of human beta-globin gene complex on chromosome 11. Proc Natl Acad Sci U S A (1979) 3.05
Quality of Scottish Morbidity Record (SMR) data. Health Bull (Edinb) (1996) 3.05
An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumor. Cell (1990) 3.02
Two independent and interactive DNA-binding subdomains of the Pax6 paired domain are regulated by alternative splicing. Genes Dev (1994) 2.99
Six-month outcome of critically ill patients given glutamine-supplemented parenteral nutrition. Nutrition (1997) 2.92
Alternative splicing and genomic structure of the Wilms tumor gene WT1. Proc Natl Acad Sci U S A (1991) 2.83
Proteasome-dependent degradation of the human estrogen receptor. Proc Natl Acad Sci U S A (1999) 2.81
FRAP reveals that mobility of oestrogen receptor-alpha is ligand- and proteasome-dependent. Nat Cell Biol (2001) 2.76
Recalibration of the delirium prediction model for ICU patients (PRE-DELIRIC): a multinational observational study. Intensive Care Med (2014) 2.71
Prevalence of high blood pressure and elevated serum creatinine level in the United States: findings from the third National Health and Nutrition Examination Survey (1988-1994). Arch Intern Med (2001) 2.69
Strategies for mapping and cloning macroregions of mammalian genomes. Methods Enzymol (1987) 2.68
Deregulation of a homeobox gene, HOX11, by the t(10;14) in T cell leukemia. Science (1991) 2.64
Relationship between dopamine D(2) occupancy, clinical response, and side effects: a double-blind PET study of first-episode schizophrenia. Am J Psychiatry (2000) 2.61
Biosynthesis of vitamin B12: identity of fragment extruded during ring contraction to the corrin macrocycle. Proc Natl Acad Sci U S A (1981) 2.60
Fli-1 is required for murine vascular and megakaryocytic development and is hemizygously deleted in patients with thrombocytopenia. Immunity (2000) 2.59
Reliability and validity of DSM-IV axis V. Am J Psychiatry (2000) 2.59
Isolation of human fibroblast catalase cDNA clones. Sequence of clones derived from spliced and unspliced mRNA. J Biol Chem (1984) 2.57
The Angelman syndrome-associated protein, E6-AP, is a coactivator for the nuclear hormone receptor superfamily. Mol Cell Biol (1999) 2.57
CDK6 (PLSTIRE) and CDK4 (PSK-J3) are a distinct subset of the cyclin-dependent kinases that associate with cyclin D1. Oncogene (1994) 2.55
A histidine-rich protein gene marks a linkage group favored strongly in a genetic cross of Plasmodium falciparum. Cell (1987) 2.53
Pulsed-field gel electrophoresis of very large DNA molecules. Annu Rev Biophys Biophys Chem (1988) 2.47
The DNA sequence and biological annotation of human chromosome 1. Nature (2006) 2.42
CINEMATOGRAPHS OF LIVING DEVELOPING RABBIT-EGGS. Science (1929) 2.41
Mammalian cell growth proteins. I. Growth stimulation of fetuin. Proc Natl Acad Sci U S A (1968) 2.40
Math5 encodes a murine basic helix-loop-helix transcription factor expressed during early stages of retinal neurogenesis. Development (1998) 2.38
Promoter-specific inhibition of transcription by antibiotics which act on DNA gyrase. Nature (1978) 2.37
N.m.r. and molecular-modelling studies of the solution conformation of heparin. Biochem J (1993) 2.36
Oxygen sensing in airway chemoreceptors. Nature (1993) 2.35
Oncogene ect2 is related to regulators of small GTP-binding proteins. Nature (1993) 2.34
P-glycoprotein expression as a predictor of the outcome of therapy for neuroblastoma. N Engl J Med (1991) 2.32
A strategy for rapid and efficient DNA sequencing by mass spectrometry. Nat Biotechnol (1996) 2.30
A fine-structure deletion map of human chromosome 11p: analysis of J1 series hybrids. Somat Cell Mol Genet (1989) 2.29
Partial physical map of human chromosome 21. Somat Cell Mol Genet (1988) 2.27
Ranitidine 150 mg twice daily vs 300 mg nightly in treatment of duodenal ulcers. Lancet (1984) 2.25
Seven polymorphic loci mapping to human chromosomal region 11q22-qter. Genomics (1988) 2.23
A rapid method for isolating high quality plasmid DNA suitable for DNA sequencing. Nucleic Acids Res (1990) 2.20
Genetics of somatic mammalian cells: genetic, immunologic, and biochemical analysis with Chinese hamster cell hybrids containing selected human chromosomes. Proc Natl Acad Sci U S A (1976) 2.20
Relationship between disease activity indices and colonoscopic findings in patients with colonic inflammatory bowel disease. Gut (1986) 2.17
Reduction in hospital time to thrombolytic therapy by audit of policy guidelines. Eur Heart J (1990) 2.17
Protein translation components are colocalized in granules in oligodendrocytes. J Cell Sci (1995) 2.13
Structure and function of Cdc6/Cdc18: implications for origin recognition and checkpoint control. Mol Cell (2000) 2.07
Nonrandom loss of maternal chromosome 11 alleles in Wilms tumors. Am J Hum Genet (1987) 2.06
X chromosome map at 75-kb STS resolution, revealing extremes of recombination and GC content. Genome Res (1997) 2.06
Proteolytic activity of human osteoclast cathepsin K. Expression, purification, activation, and substrate identification. J Biol Chem (1996) 2.06
Megabase-scale mapping of the HLA gene complex by pulsed field gel electrophoresis. Science (1987) 2.01
Photodynamic therapy for the treatment of basal cell carcinoma. Arch Dermatol (1992) 2.01
Genetics of somatic mammalian cells: lethal antigens as genetic markers for study of human linkage groups. Proc Natl Acad Sci U S A (1971) 2.00
Terlipressin therapy for moderate-to-severe hyponatraemia in patients with liver failure. Intern Med J (2013) 2.00
Absence of cyclin D/cdk complexes in cells lacking functional retinoblastoma protein. Oncogene (1994) 1.99
A specific histochemical marker (lectin Ricinus communis agglutinin-1) for normal human microglia, and application to routine histopathology. Acta Neuropathol (1986) 1.98
Proposal for a unified CCN nomenclature. Mol Pathol (2003) 1.98
Synteny between glycinamide ribonucleotide synthetase and superoxide dismutase (soluble). Am J Hum Genet (1977) 1.97