Published in Curr Protoc Toxicol on May 01, 2011
Role of manganese in neurodegenerative diseases. J Trace Elem Med Biol (2011) 1.73
DMH1, a highly selective small molecule BMP inhibitor promotes neurogenesis of hiPSCs: comparison of PAX6 and SOX1 expression during neural induction. ACS Chem Neurosci (2012) 1.11
Metals, oxidative stress and neurodegeneration: a focus on iron, manganese and mercury. Neurochem Int (2012) 0.99
Manganese-Induced Parkinsonism and Parkinson's Disease: Shared and Distinguishable Features. Int J Environ Res Public Health (2015) 0.86
Optimization of fluorescence assay of cellular manganese status for high throughput screening. J Biochem Mol Toxicol (2012) 0.79
Redox dynamics of manganese as a mitochondrial life-death switch. Biochem Biophys Res Commun (2017) 0.75
A new generation of Ca2+ indicators with greatly improved fluorescence properties. J Biol Chem (1985) 90.20
Measurement of cytosolic free Ca2+ with quin2. Methods Enzymol (1989) 4.33
Dominant phenotypes produced by the HD mutation in STHdh(Q111) striatal cells. Hum Mol Genet (2000) 3.87
PicoGreen quantitation of DNA: effective evaluation of samples pre- or post-PCR. Nucleic Acids Res (1996) 3.74
Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1. Neuron (2003) 3.25
Use of manganese to discriminate between calcium influx and mobilization from internal stores in stimulated human neutrophils. J Biol Chem (1989) 3.06
Fluorescence and bioluminescence measurement of cytoplasmic free calcium. Biochem J (1987) 3.00
Fluorescent probes of cell signaling. Annu Rev Neurosci (1989) 2.71
Molecular diversity of voltage-dependent Ca2+ channels. Trends Pharmacol Sci (1991) 2.25
Manganese: recent advances in understanding its transport and neurotoxicity. Toxicol Appl Pharmacol (2007) 2.17
Iron, manganese, and cobalt transport by Nramp1 (Slc11a1) and Nramp2 (Slc11a2) expressed at the plasma membrane. Blood (2003) 1.63
Nramp 2 (DCT1/DMT1) expressed at the plasma membrane transports iron and other divalent cations into a calcein-accessible cytoplasmic pool. J Biol Chem (2000) 1.45
Manganese uptake and efflux in cultured rat astrocytes. J Neurochem (1992) 1.26
Calcium homeostasis and mitochondrial dysfunction in striatal neurons of Huntington disease. J Biol Chem (2007) 1.21
Manganese neurotoxicity and glutamate-GABA interaction. Neurochem Int (2003) 1.20
Mitochondrial-dependent Ca2+ handling in Huntington's disease striatal cells: effect of histone deacetylase inhibitors. J Neurosci (2006) 1.19
Disease-toxicant screen reveals a neuroprotective interaction between Huntington's disease and manganese exposure. J Neurochem (2009) 1.00
Endogenous heavy metal ions perturb fura-2 measurements of basal and hormone-evoked Ca2+ signals. Biophys J (1996) 0.95
Fluorometric assay for DNA polymerases and reverse transcriptase. Biotechniques (1996) 0.91
Altered manganese homeostasis and manganese toxicity in a Huntington's disease striatal cell model are not explained by defects in the iron transport system. Toxicol Sci (2010) 0.91
Effect of manganese exposure on intracellular Ca2+ homeostasis and expression of NMDA receptor subunits in primary cultured neurons. Neurotoxicology (2009) 0.88
Changes in nine enzyme markers for neurons, glia, and endothelial cells in agonal state and Huntington's disease caudate nucleus. J Neurochem (1986) 0.88
Novel high-throughput assay to assess cellular manganese levels in a striatal cell line model of Huntington's disease confirms a deficit in manganese accumulation. Neurotoxicology (2011) 0.87
Determination of manganese in biological materials by electrothermal atomic absorption spectrometry: a review. Clin Chem (1988) 0.80
Use of the fluorescent dye PicoGreen for quantification of PCR products after agarose gel electrophoresis. Biotechniques (1996) 0.78
Opposing effects of polyglutamine expansion on native protein complexes contribute to SCA1. Nature (2008) 3.68
ATAXIN-1 interacts with the repressor Capicua in its native complex to cause SCA1 neuropathology. Cell (2006) 3.39
Regulation of RNA splicing by the methylation-dependent transcriptional repressor methyl-CpG binding protein 2. Proc Natl Acad Sci U S A (2005) 2.90
Glutamine-expanded ataxin-7 alters TFTC/STAGA recruitment and chromatin structure leading to photoreceptor dysfunction. PLoS Biol (2006) 2.12
Ferroportin is a manganese-responsive protein that decreases manganese cytotoxicity and accumulation. J Neurochem (2009) 1.23
ATXN1 protein family and CIC regulate extracellular matrix remodeling and lung alveolarization. Dev Cell (2011) 1.12
DMH1, a highly selective small molecule BMP inhibitor promotes neurogenesis of hiPSCs: comparison of PAX6 and SOX1 expression during neural induction. ACS Chem Neurosci (2012) 1.11
Role of astrocytes in brain function and disease. Toxicol Pathol (2010) 1.06
DHCEO accumulation is a critical mediator of pathophysiology in a Smith-Lemli-Opitz syndrome model. Neurobiol Dis (2011) 1.05
Manganese Is Essential for Neuronal Health. Annu Rev Nutr (2015) 1.03
Disease-toxicant screen reveals a neuroprotective interaction between Huntington's disease and manganese exposure. J Neurochem (2009) 1.00
Disease-toxicant interactions in manganese exposed Huntington disease mice: early changes in striatal neuron morphology and dopamine metabolism. PLoS One (2012) 0.92
Lipid modifications of Sonic hedgehog ligand dictate cellular reception and signal response. PLoS One (2011) 0.91
Altered manganese homeostasis and manganese toxicity in a Huntington's disease striatal cell model are not explained by defects in the iron transport system. Toxicol Sci (2010) 0.91
Genetic risk for Parkinson's disease correlates with alterations in neuronal manganese sensitivity between two human subjects. Neurotoxicology (2012) 0.89
Gender and manganese exposure interactions on mouse striatal neuron morphology. Neurotoxicology (2011) 0.88
Morphometric analysis in neurodegenerative disorders. Curr Protoc Toxicol (2010) 0.88
Novel high-throughput assay to assess cellular manganese levels in a striatal cell line model of Huntington's disease confirms a deficit in manganese accumulation. Neurotoxicology (2011) 0.87
The potential of induced pluripotent stem cells as a translational model for neurotoxicological risk. Neurotoxicology (2012) 0.82
Untargeted metabolic profiling identifies interactions between Huntington's disease and neuronal manganese status. Metallomics (2015) 0.80
Changes in the striatal proteome of YAC128Q mice exhibit gene-environment interactions between mutant huntingtin and manganese. J Proteome Res (2012) 0.80
Age- and manganese-dependent modulation of dopaminergic phenotypes in a C. elegans DJ-1 genetic model of Parkinson's disease. Metallomics (2015) 0.80
BDNF and Huntingtin protein modifications by manganese: implications for striatal medium spiny neuron pathology in manganese neurotoxicity. J Neurochem (2014) 0.79
Optimization of fluorescence assay of cellular manganese status for high throughput screening. J Biochem Mol Toxicol (2012) 0.79
Loss of pdr-1/parkin influences Mn homeostasis through altered ferroportin expression in C. elegans. Metallomics (2015) 0.77
Novel BAC Mouse Model of Huntington's Disease with 225 CAG Repeats Exhibits an Early Widespread and Stable Degenerative Phenotype. J Huntingtons Dis (2015) 0.76