Nutritional Status Driving Infection by Trypanosoma cruzi: Lessons from Experimental Animals.

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Published in J Trop Med on April 14, 2011

Authors

Guilherme Malafaia1, André Talvani

Author Affiliations

1: Departamento de Ciências Biológicas, Núcleo de Pesquisas e Estudos Ambientais e Biológicos, Instituto Federal de Educação, Ciência e Tecnologia Goiano-Campus Urutaí, Rodovia Geraldo Silva Nascimento km 2.5, 75790-000 Urutaí, GO, Brazil.

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Zinc and immune function: the biological basis of altered resistance to infection. Am J Clin Nutr (1998) 4.23

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Interactions of nutrition and infection. Monogr Ser World Health Organ (1968) 2.46

Iron and its relation to immunity and infectious disease. J Nutr (2001) 2.41

The interaction between nutrition and infection. Clin Infect Dis (2008) 2.39

The immune system. First of two parts. N Engl J Med (2000) 2.05

Pathophysiology of the heart in Chagas' disease: current status and new developments. Cardiovasc Res (2003) 1.97

Regulation of Trypanosoma cruzi infection in mice by gamma interferon and interleukin 10: role of NK cells. Infect Immun (1996) 1.93

Chagas disease: what is known and what is needed--a background article. Mem Inst Oswaldo Cruz (2007) 1.90

Oral transmission of Chagas disease by consumption of açaí palm fruit, Brazil. Emerg Infect Dis (2009) 1.80

The role of natural killer cells in host-parasite interactions. Curr Opin Immunol (1995) 1.77

Nutrients and their role in host resistance to infection. J Leukoc Biol (2002) 1.76

Genetic Variability of Trypanosoma cruzi:Implications for the Pathogenesis of Chagas Disease. Parasitol Today (1998) 1.65

Kinetics of cytokine gene expression in experimental chagasic cardiomyopathy: tissue parasitism and endogenous IFN-gamma as important determinants of chemokine mRNA expression during infection with Trypanosoma cruzi. Microbes Infect (2000) 1.63

An update on Chagas disease (human American trypanosomiasis). Ann Trop Med Parasitol (2006) 1.43

Depletion of T-cell subpopulations results in exacerbation of myocarditis and parasitism in experimental Chagas' disease. Infect Immun (1994) 1.38

Malnutrition alters the innate immune response and increases early visceralization following Leishmania donovani infection. Infect Immun (2001) 1.37

Nutritional aspects of HIV-associated wasting in sub-Saharan Africa. Am J Clin Nutr (2010) 1.35

Evolution and pathology in chagas disease--a review. Mem Inst Oswaldo Cruz (2006) 1.33

Assessment by flow cytometry of cytokine production in malnourished children. Clin Diagn Lab Immunol (2005) 1.30

Red cell transketolase as an indicator of nutritional deficiency. Am J Clin Nutr (1980) 1.26

Interactions of malnutrition and immune impairment, with specific reference to immunity against parasites. Parasite Immunol (2006) 1.24

Flow cytometry study of lymphocyte subsets in malnourished and well-nourished children with bacterial infections. Clin Diagn Lab Immunol (2004) 1.20

Role of iron in Trypanosoma cruzi infection of mice. J Clin Invest (1984) 1.18

Prevalence of CD8(+)alpha beta T cells in Trypanosoma cruzi-elicited myocarditis is associated with acquisition of CD62L(Low)LFA-1(High)VLA-4(High) activation phenotype and expression of IFN-gamma-inducible adhesion and chemoattractant molecules. Microbes Infect (2001) 1.17

Nutrition and infectious diseases in developing countries and problems of acquired immunodeficiency syndrome. Exp Biol Med (Maywood) (2004) 1.15

Elevated concentrations of CCL2 and tumor necrosis factor-alpha in chagasic cardiomyopathy. Clin Infect Dis (2004) 1.14

Serum complement and immunoconglutinin in malnutrition. Arch Dis Child (1975) 1.12

Update of cell damage mechanisms in thiamine deficiency: focus on oxidative stress, excitotoxicity and inflammation. Alcohol Alcohol (2009) 1.11

Gastrointestinal aspects of Chagas' disease. Am J Dig Dis (1972) 1.10

CD45RA and CD45RO isoforms in infected malnourished and infected well-nourished children. Clin Exp Immunol (2001) 1.09

Regulation of cell signalling by vitamin E. Proc Nutr Soc (2002) 1.08

Assessment of nutritional status on hospital admission: nutritional scores. Eur J Clin Nutr (2003) 1.07

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Chemokine receptor expression on the surface of peripheral blood mononuclear cells in Chagas disease. J Infect Dis (2004) 0.96

Innate immunity and regulatory T-cells in human Chagas disease: what must be understood? Mem Inst Oswaldo Cruz (2009) 0.93

Diagnosis and treatment of (disease-related) in-hospital malnutrition: the performance of medical and nursing staff. Clin Nutr (2008) 0.92

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Malnutrition and infection: an update. Br J Nutr (2007) 0.91

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Correlation between zinc status and immune function in the elderly. Biogerontology (2006) 0.90

The thymus gland: a target organ for growth hormone. Scand J Immunol (2002) 0.90

Protein energy malnutrition. Pediatr Clin North Am (2009) 0.90

Protein-energy malnutrition decreases immune response to Leishmania chagasi vaccine in BALB/c mice. Parasite Immunol (2009) 0.90

Effect of malnutrition on susceptibility of rats to Trypanosoma cruzi. I. Thiamine deficiency. Exp Parasitol (1960) 0.89

Cellular immunity to Trypanosoma cruzi is mediated by helper T cells (CD4+). Trans R Soc Trop Med Hyg (1988) 0.89

Trace elements in human health with special reference to selenium. Am J Clin Nutr (1987) 0.88

T cells with a quiescent phenotype (CD45RA+) are overabundant in the blood and involuted lymphoid tissues in wasting protein and energy deficiencies. Immunology (1999) 0.88

Vitamin B6 and immune competence. Nutr Rev (1993) 0.88

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Effect of antioxidative vitamins on immune function with clinical applications. Int J Vitam Nutr Res (1997) 0.86

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Retracted Blood concentrations of Th2-type immunoglobulins are selectively increased in weanling mice subjected to acute malnutrition. Exp Biol Med (Maywood) (2005) 0.85

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[Epidemiologic determinants of Chagas' disease in Brazil: the infection, the disease and its morbidity/mortality]. Mem Inst Oswaldo Cruz (1988) 0.83

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Endotoxin induced production of interleukin-6 is enhanced by vitamin E deficiency and reduced by black tea extract. Inflamm Res (1995) 0.81

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EFFECT OF MALNUTRITION ON SUSCEPTIBILITY OF RATS TO TRYPANOSOMA CRUZI. V. VITAMIN A DEFICIENCY. Exp Parasitol (1963) 0.78

[Humoral immunity, 5 years after anti-tetanus vaccination, in a group of malaria-infected and malnourished African children]. Pathol Biol (Paris) (1988) 0.78

Effect of malnutrition on susceptibility of rats to Trypanosoma cruzi. II. Riboflavin deficiency. Exp Parasitol (1960) 0.78

Effect of malnutrition on susceptibility of rats to Trypanosoma cruzi. IV. Pyridoxine deficiency. Exp Parasitol (1960) 0.78

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Vitamin E deficiency enhances pathology in acute Trypanosoma cruzi-infected rats. Trans R Soc Trop Med Hyg (2006) 0.76

Chronic malnutrition and Trypanosoma cruzi infection in children. J Trop Pediatr (1995) 0.76

Effects of severe protein restriction in levels of parasitemia and in mortality of mice acutely infected with Trypanosoma cruzi. Rev Soc Bras Med Trop (1994) 0.76

The effect of iron nutritional status on Trypanosoma cruzi infection in germfree and conventional mice. Comp Biochem Physiol Comp Physiol (1993) 0.76

Trypanosoma cruzi antigen-specific antibody response in immunized mice during acute and chronic infection. J Parasitol (1990) 0.76

Trypanosoma cruzi: Different methods of data analysis to evaluate the genetics-biology relationship. Exp Parasitol (2009) 0.76

Immature circulating lymphocytes in severely malnourished Guatemalan children. J Pediatr Gastroenterol Nutr (1988) 0.76

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Benznidazole alters the pattern of Cyclophosphamide-induced reactivation in experimental Trypanosoma cruzi-dependent lineage infection. Acta Trop (2009) 0.76

Serum opsonic activity in acute protein-energy malnutrition. Bull World Health Organ (1981) 0.76

Immunomodulatory effects of zinc and DHEA on the Th-1 immune response in rats infected with Trypanosoma cruzi. Immunobiology (2009) 0.76

Cardiac noradrenalin in relation to protein malnutrition in chronic experimental Chagas' disease in the rat. Am J Trop Med Hyg (1984) 0.75

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