Published in Blood on June 27, 2011
Induced pluripotent stem cells--opportunities for disease modelling and drug discovery. Nat Rev Drug Discov (2011) 2.58
Blood-derived human iPS cells generate optic vesicle-like structures with the capacity to form retinal laminae and develop synapses. Invest Ophthalmol Vis Sci (2012) 1.50
Patient-specific hepatocyte-like cells derived from induced pluripotent stem cells model pazopanib-mediated hepatotoxicity. Sci Rep (2017) 1.38
Specimen collection for induced pluripotent stem cell research: harmonizing the approach to informed consent. Stem Cells Transl Med (2012) 1.24
Efficient generation of integration-free ips cells from human adult peripheral blood using BCL-XL together with Yamanaka factors. PLoS One (2013) 1.06
Modeling heterogeneous patients with a clinical diagnosis of schizophrenia with induced pluripotent stem cells. Biol Psychiatry (2013) 1.05
Modeling chemotherapeutic neurotoxicity with human induced pluripotent stem cell-derived neuronal cells. PLoS One (2015) 1.02
Reliable generation of induced pluripotent stem cells from human lymphoblastoid cell lines. Stem Cells Transl Med (2014) 0.95
Cellular reprogramming of human peripheral blood cells. Genomics Proteomics Bioinformatics (2013) 0.94
Reprogramming LCLs to iPSCs Results in Recovery of Donor-Specific Gene Expression Signature. PLoS Genet (2015) 0.86
Induced pluripotent stem cells from GMP-grade hematopoietic progenitor cells and mononuclear myeloid cells. Stem Cell Res Ther (2011) 0.85
HapMap SNP Scanner: an online program to mine SNPs responsible for cell phenotype. Tissue Antigens (2012) 0.80
In vitro human cell line models to predict clinical response to anticancer drugs. Pharmacogenomics (2015) 0.79
Human iPSC-derived neurons and lymphoblastoid cells for personalized medicine research in neuropsychiatric disorders. Dialogues Clin Neurosci (2016) 0.77
C9orf72 promoter hypermethylation is reduced while hydroxymethylation is acquired during reprogramming of ALS patient cells. Exp Neurol (2015) 0.77
The Generation of Human Induced Pluripotent Stem Cells from Blood Cells: An Efficient Protocol Using Serial Plating of Reprogrammed Cells by Centrifugation. Stem Cells Int (2016) 0.76
Induced pluripotent stem cells in hematology: current and future applications. Blood Cancer J (2014) 0.76
Modeling neurological diseases with induced pluripotent cells reprogrammed from immortalized lymphoblastoid cell lines. Mol Brain (2016) 0.75
Will brain cells derived from induced pluripotent stem cells or directly converted from somatic cells (iNs) be useful for schizophrenia research? Schizophr Bull (2013) 0.75
Utility of Lymphoblastoid Cell Lines for Induced Pluripotent Stem Cell Generation. Stem Cells Int (2016) 0.75
Modulation of human allogeneic and syngeneic pluripotent stem cells and immunological implications for transplantation. Transplant Rev (Orlando) (2016) 0.75
Induced pluripotent stem cell lines derived from human somatic cells. Science (2007) 71.50
Human induced pluripotent stem cells free of vector and transgene sequences. Science (2009) 17.16
Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency. Cell (2008) 10.68
Strategies and new developments in the generation of patient-specific pluripotent stem cells. Cell Stem Cell (2007) 6.62
Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures. Cell Res (2011) 3.58
The coupling of synthesis and partitioning of EBV's plasmid replicon is revealed in live cells. EMBO J (2007) 2.71
Open chromatin in pluripotency and reprogramming. Nat Rev Mol Cell Biol (2011) 2.69
EBNA-1: a protein pivotal to latent infection by Epstein-Barr virus. Rev Med Virol (2000) 2.12
Efficient generation of transgene-free induced pluripotent stem cells from normal and neoplastic bone marrow and cord blood mononuclear cells. Blood (2011) 1.92
Transcriptional activation by EBV nuclear antigen 1 is essential for the expression of EBV's transforming genes. Proc Natl Acad Sci U S A (2006) 1.81
Efficient feeder-free episomal reprogramming with small molecules. PLoS One (2011) 1.79
Epstein-Barr virus quantitation by real-time PCR targeting multiple gene segments: a novel approach to screen for the virus in paraffin-embedded tissue and plasma. J Mol Diagn (2004) 1.64
Developmental plasticity of lymphocytes. Curr Opin Immunol (2008) 1.29
EBV Immortalization of human B lymphocytes separated from small volumes of cryo-preserved whole blood. Int J Epidemiol (2008) 1.08
Proof for EBV's sustaining role in Burkitt's lymphomas. Semin Cancer Biol (2009) 0.99
Successful differentiation to T cells, but unsuccessful B-cell generation, from B-cell-derived induced pluripotent stem cells. Int Immunol (2010) 0.96
Reprogramming of B cells. Methods Mol Biol (2010) 0.88
Transcription profiling of Epstein-Barr virus nuclear antigen (EBNA)-1 expressing cells suggests targeting of chromatin remodeling complexes. PLoS One (2010) 0.87
Clonotypic B cells in classic Hodgkin lymphoma. Blood (2009) 0.83
Induced pluripotent stem cell lines derived from human somatic cells. Science (2007) 71.50
Human DNA methylomes at base resolution show widespread epigenomic differences. Nature (2009) 34.27
Histone modifications at human enhancers reflect global cell-type-specific gene expression. Nature (2009) 24.41
Human induced pluripotent stem cells free of vector and transgene sequences. Science (2009) 17.16
The NIH Roadmap Epigenomics Mapping Consortium. Nat Biotechnol (2010) 13.99
Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells. Nature (2011) 13.94
ProbeMatch: rapid alignment of oligonucleotides to genome allowing both gaps and mismatches. Bioinformatics (2009) 13.34
Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature (2008) 12.21
RNA-Seq gene expression estimation with read mapping uncertainty. Bioinformatics (2009) 10.74
Somatic coding mutations in human induced pluripotent stem cells. Nature (2011) 9.50
Recurrent gain of chromosomes 17q and 12 in cultured human embryonic stem cells. Nat Biotechnol (2003) 9.15
Distinct epigenomic landscapes of pluripotent and lineage-committed human cells. Cell Stem Cell (2010) 8.74
Whole-genome analysis of histone H3 lysine 4 and lysine 27 methylation in human embryonic stem cells. Cell Stem Cell (2007) 8.59
Derivation of human embryonic stem cells in defined conditions. Nat Biotechnol (2006) 8.28
MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells. Cell (2009) 8.14
Feeder-independent culture of human embryonic stem cells. Nat Methods (2006) 7.61
Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming. Nat Biotechnol (2009) 7.59
Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency. Proc Natl Acad Sci U S A (2010) 7.31
Functional cardiomyocytes derived from human induced pluripotent stem cells. Circ Res (2009) 7.09
Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells. Nat Methods (2005) 6.37
BMP4 initiates human embryonic stem cell differentiation to trophoblast. Nat Biotechnol (2002) 6.20
Chemically defined conditions for human iPSC derivation and culture. Nat Methods (2011) 5.84
Homologous recombination in human embryonic stem cells. Nat Biotechnol (2003) 5.77
Human embryonic stem cells develop into multiple types of cardiac myocytes: action potential characterization. Circ Res (2003) 5.12
NANOG is a direct target of TGFbeta/activin-mediated SMAD signaling in human ESCs. Cell Stem Cell (2008) 4.88
EBSeq: an empirical Bayes hierarchical model for inference in RNA-seq experiments. Bioinformatics (2013) 4.79
Gene expression patterns in human embryonic stem cells and human pluripotent germ cell tumors. Proc Natl Acad Sci U S A (2003) 4.67
Human embryonic stem cell-derived CD34+ cells: efficient production in the coculture with OP9 stromal cells and analysis of lymphohematopoietic potential. Blood (2004) 4.32
Epigenomic analysis of multilineage differentiation of human embryonic stem cells. Cell (2013) 3.81
Nanog and transcriptional networks in embryonic stem cell pluripotency. Cell Res (2007) 3.56
Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis. Proc Natl Acad Sci U S A (2013) 3.53
Hematopoietic and endothelial differentiation of human induced pluripotent stem cells. Stem Cells (2009) 3.46
Directed differentiation of dopaminergic neuronal subtypes from human embryonic stem cells. Stem Cells (2005) 3.38
Cell type-specific DNA methylation patterns in the human breast. Proc Natl Acad Sci U S A (2008) 2.99
Extracellular matrix promotes highly efficient cardiac differentiation of human pluripotent stem cells: the matrix sandwich method. Circ Res (2012) 2.91
Basic fibroblast growth factor support of human embryonic stem cell self-renewal. Stem Cells (2005) 2.78
Actin-myosin contractility is responsible for the reduced viability of dissociated human embryonic stem cells. Cell Stem Cell (2010) 2.69
Caspase activity mediates the differentiation of embryonic stem cells. Cell Stem Cell (2008) 2.68
Leukosialin (CD43) defines hematopoietic progenitors in human embryonic stem cell differentiation cultures. Blood (2006) 2.66
High purity human-induced pluripotent stem cell-derived cardiomyocytes: electrophysiological properties of action potentials and ionic currents. Am J Physiol Heart Circ Physiol (2011) 2.65
A mesoderm-derived precursor for mesenchymal stem and endothelial cells. Cell Stem Cell (2010) 2.58
Surface antigens of human embryonic stem cells: changes upon differentiation in culture. J Anat (2002) 2.52
High-level sustained transgene expression in human embryonic stem cells using lentiviral vectors. Stem Cells (2003) 2.42
Genetic correction and analysis of induced pluripotent stem cells from a patient with gyrate atrophy. Proc Natl Acad Sci U S A (2011) 2.41
Proteomic and phosphoproteomic comparison of human ES and iPS cells. Nat Methods (2011) 2.39
Mass spectrometry identifies and quantifies 74 unique histone H4 isoforms in differentiating human embryonic stem cells. Proc Natl Acad Sci U S A (2008) 2.29
Optic vesicle-like structures derived from human pluripotent stem cells facilitate a customized approach to retinal disease treatment. Stem Cells (2011) 2.26
Pluripotent stem cell lines. Genes Dev (2008) 2.25
Ronin is essential for embryogenesis and the pluripotency of mouse embryonic stem cells. Cell (2008) 2.21
Trophoblast differentiation in embryoid bodies derived from human embryonic stem cells. Endocrinology (2003) 2.15
FGF2 sustains NANOG and switches the outcome of BMP4-induced human embryonic stem cell differentiation. Cell Stem Cell (2011) 2.11
A germ cell origin of embryonic stem cells? Development (2005) 2.09
Defined substrates for human embryonic stem cell growth identified from surface arrays. ACS Chem Biol (2007) 2.08
Quantitative selection of DNA aptamers through microfluidic selection and high-throughput sequencing. Proc Natl Acad Sci U S A (2010) 2.01
Human embryonic stem cell phosphoproteome revealed by electron transfer dissociation tandem mass spectrometry. Proc Natl Acad Sci U S A (2009) 1.95
Efficient generation of transgene-free induced pluripotent stem cells from normal and neoplastic bone marrow and cord blood mononuclear cells. Blood (2011) 1.92
Passaging and colony expansion of human pluripotent stem cells by enzyme-free dissociation in chemically defined culture conditions. Nat Protoc (2012) 1.74
Dynamic chromatin states in human ES cells reveal potential regulatory sequences and genes involved in pluripotency. Cell Res (2011) 1.72
Absence of the DNA-/RNA-binding protein MSY2 results in male and female infertility. Proc Natl Acad Sci U S A (2005) 1.71
Crystallographic identification of a noncompetitive inhibitor binding site on the hepatitis C virus NS5B RNA polymerase enzyme. J Virol (2003) 1.57
Conserved regulation of MAP kinase expression by PUF RNA-binding proteins. PLoS Genet (2007) 1.51
Blood-derived human iPS cells generate optic vesicle-like structures with the capacity to form retinal laminae and develop synapses. Invest Ophthalmol Vis Sci (2012) 1.50
A study of the relationships between oligonucleotide properties and hybridization signal intensities from NimbleGen microarray datasets. Nucleic Acids Res (2008) 1.47
The microwell control of embryoid body size in order to regulate cardiac differentiation of human embryonic stem cells. Biomaterials (2009) 1.46
Identification of the hemogenic endothelial progenitor and its direct precursor in human pluripotent stem cell differentiation cultures. Cell Rep (2012) 1.46
Evaluation of de novo transcriptome assemblies from RNA-Seq data. Genome Biol (2014) 1.46
X-box-binding protein 1 activates lytic Epstein-Barr virus gene expression in combination with protein kinase D. J Virol (2007) 1.45
MicroRNA 92b controls the G1/S checkpoint gene p57 in human embryonic stem cells. Stem Cells (2009) 1.43
Arrays for the combinatorial exploration of cell adhesion. J Am Chem Soc (2004) 1.41
Directed differentiation of human embryonic stem cells into functional dendritic cells through the myeloid pathway. J Immunol (2006) 1.34
Generation of red blood cells from human induced pluripotent stem cells. Stem Cells Dev (2011) 1.25
Functional endothelial cells derived from rhesus monkey embryonic stem cells. Blood (2003) 1.25
The effects of adult guidance and peer discussion on the development of children's representations: evidence from the training of pedestrian skills. Br J Psychol (2005) 1.24
Human embryonic stem cell-derived hematopoietic cells are capable of engrafting primary as well as secondary fetal sheep recipients. Blood (2005) 1.23
Dielectrophoretic separation of platelets from diluted whole blood in microfluidic channels. Electrophoresis (2008) 1.20
Phosphorylation regulates human OCT4. Proc Natl Acad Sci U S A (2012) 1.19
Human embryonic stem cells reprogram myeloid precursors following cell-cell fusion. Stem Cells (2005) 1.17
LongSAGE profiling of nine human embryonic stem cell lines. Genome Biol (2007) 1.15
Optical mapping discerns genome wide DNA methylation profiles. BMC Mol Biol (2008) 1.14
ZEB1 and c-Jun levels contribute to the establishment of highly lytic Epstein-Barr virus infection in gastric AGS cells. J Virol (2007) 1.14
Quantitative selection and parallel characterization of aptamers. Proc Natl Acad Sci U S A (2013) 1.13
Comparative RNA-seq analysis in the unsequenced axolotl: the oncogene burst highlights early gene expression in the blastema. PLoS Comput Biol (2013) 1.11
Instant spectral assignment for advanced decision tree-driven mass spectrometry. Proc Natl Acad Sci U S A (2012) 1.08
Differentiation of human embryonic stem cells occurs through symmetric cell division. Stem Cells (2005) 1.04
Secreted proteoglycans directly mediate human embryonic stem cell-basic fibroblast growth factor 2 interactions critical for proliferation. Stem Cells (2008) 1.01
Modeling human retinal development with patient-specific induced pluripotent stem cells reveals multiple roles for visual system homeobox 2. Stem Cells (2014) 0.99
No evidence for clonal selection due to lentiviral integration sites in human induced pluripotent stem cells. Stem Cells (2010) 0.99
Sumoylation of the Epstein-Barr virus BZLF1 protein inhibits its transcriptional activity and is regulated by the virus-encoded protein kinase. J Virol (2010) 0.99