Published in Biochemistry on February 20, 1979
Calcineurin: a calcium- and calmodulin-binding protein of the nervous system. Proc Natl Acad Sci U S A (1979) 3.33
Function of a calmodulin in postsynaptic densities. III. Calmodulin-binding proteins of the postsynaptic density. J Cell Biol (1981) 1.89
A molecular description of nerve terminal function. Annu Rev Biochem (1983) 1.82
Purification of two calcium/calmodulin-dependent forms of cyclic nucleotide phosphodiesterase by using conformation-specific monoclonal antibody chromatography. Proc Natl Acad Sci U S A (1982) 1.68
Purification and properties of the insulin-stimulated cyclic AMP phosphodiesterase from rat liver plasma membranes. Biochem J (1981) 1.58
Function of calmodulin in postsynaptic densities. I. Presence of a calmodulin-activatable cyclic nucleotide phosphodiesterase activity. J Cell Biol (1981) 0.91
Expression of the functional cone phototransduction cascade in retinoblastoma. J Clin Invest (1990) 0.91
Heterogeneity of cyclic nucleotide phosphodiesterases in liver endoplasmic reticulum. Biochem J (1983) 0.88
Submitochondrial localization and asymmetric disposition of two peripheral cyclic nucleotide phosphodiesterases. Biochem J (1982) 0.88
Sequential adsorption-electrophoresis: combined procedure for purification of calcium-dependent cyclic nucleotide phosphodiesterase. Proc Natl Acad Sci U S A (1979) 0.87
Characterization of a calmodulin-binding protein that is deficient in trifluoperazine-resistant variants of the macrophage-like cell line J774. Proc Natl Acad Sci U S A (1983) 0.84
Purification and kinetic properties of two soluble forms of calmodulin-dependent cyclic nucleotide phosphodiesterase from rat pancreas. Biochem J (1983) 0.84
The effect of K-252a, a potent microbial inhibitor of protein kinase, on activated cyclic nucleotide phosphodiesterase. Biochem J (1988) 0.82
Regulation of reactivated elongation in lysed cell models of teleost retinal cones by cAMP and calcium. J Cell Biol (1986) 0.80
Characterization of a calmodulin-dependent high-affinity cyclic AMP and cyclic GMP phosphodiesterase from male mouse germ cells. Biochem J (1984) 0.77
Studies on the soluble phosphodiesterases of chicken gizzard smooth muscle. Biochem J (1983) 0.75
Isolation of a 5.3-S calmodulin-deficient 3':5'-cyclic nucleotide phosphodiesterase from cardiac muscle. Biochem J (1982) 0.75
Postreceptor signal transduction by cyclic adenosine monophosphate and the Ca2+-calmodulin complex. J Cell Biol (1984) 0.75
Solution structure of a calmodulin-target peptide complex by multidimensional NMR. Science (1992) 6.16
Calmodulin. Annu Rev Biochem (1980) 4.22
Calmodulin. Adv Protein Chem (1982) 3.89
Identification of the NH2-terminal blocking group of calcineurin B as myristic acid. FEBS Lett (1982) 3.42
Solution structure of calcium-free calmodulin. Nat Struct Biol (1995) 3.36
Calcineurin: a calcium- and calmodulin-binding protein of the nervous system. Proc Natl Acad Sci U S A (1979) 3.33
Solution structure of Ca(2+)-calmodulin reveals flexible hand-like properties of its domains. Nat Struct Biol (2001) 3.18
Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activity. Biochemistry (1992) 3.05
Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A. Proc Natl Acad Sci U S A (1992) 2.98
Purification of cyclic 3',5'-nucleotide phosphodiesterase inhibitory protein by affinity chromatography on activator protein coupled to Sepharose. Biochemistry (1978) 2.89
Purification and characterization of smooth muscle myosin light chain kinase. J Biol Chem (1981) 2.84
Discovery of a Ca2+- and calmodulin-dependent protein phosphatase: probable identity with calcineurin (CaM-BP80). FEBS Lett (1982) 2.75
Changes in D(--)-beta-hydroxybutyric dehydrogenase activity during brain maturation in the rat. J Biol Chem (1967) 2.55
Conformational transition accompanying the binding of Ca2+ to the protein activator of 3',5'-cyclic adenosine monophosphate phosphodiesterase. Biochemistry (1977) 2.34
Phosphorylation of smooth muscle myosin light chain kinase by the catalytic subunit of adenosine 3': 5'-monophosphate-dependent protein kinase. J Biol Chem (1978) 2.33
Calcineurin: from structure to function. Curr Top Cell Regul (2000) 2.10
Positive cooperative binding of calcium to bovine brain calmodulin. Biochemistry (1980) 2.08
Dual calcium ion regulation of calcineurin by calmodulin and calcineurin B. Biochemistry (1994) 2.02
Effects of cations on affinity of calmodulin for calcium: ordered binding of calcium ions allows the specific activation of calmodulin-stimulated enzymes. Biochemistry (1981) 1.87
Functional domain structure of calcineurin A: mapping by limited proteolysis. Biochemistry (1989) 1.86
Activation of calcineurin by limited proteolysis. Proc Natl Acad Sci U S A (1983) 1.85
Calmodulin. Adv Cyclic Nucleotide Protein Phosphorylation Res (1984) 1.65
Ca2+ binding and conformational change in two series of point mutations to the individual Ca(2+)-binding sites of calmodulin. J Biol Chem (1992) 1.64
Inhibition of neutrophil chemokinesis on vitronectin by inhibitors of calcineurin. Science (1992) 1.53
Cloning of human calcineurin A: evidence for two isozymes and identification of a polyproline structural domain. Proc Natl Acad Sci U S A (1989) 1.52
Superoxide dismutase protects calcineurin from inactivation. Nature (1996) 1.32
The processive degradation of individual polyribonucleotide chains. II. Micrococcus lysodeikticus polynucleotide phosphorylase. J Biol Chem (1968) 1.26
Isolation and characterization of bovine brain calcineurin: a calmodulin-stimulated protein phosphatase. Methods Enzymol (1983) 1.23
Dephosphorylation of phosphopeptides by calcineurin (protein phosphatase 2B). Eur J Biochem (1994) 1.23
Calmodulin binding by calcineurin. Ligand-induced renaturation of protein immobilized on nitrocellulose. J Biol Chem (1987) 1.22
Purification of smooth muscle myosin light-chain kinase. Methods Enzymol (1982) 1.21
Interaction of calmodulin with myosin light chain kinase and cAMP-dependent protein kinase in bovine brain. J Biol Chem (1981) 1.21
Identification, characterization, and functional correlation of calmodulin-dependent protein phosphatase in sperm. J Cell Biol (1988) 1.19
Calcium modulation of inositol 1,4,5-trisphosphate-induced calcium release from neuroblastoma x glioma hybrid (NG108-15) microsomes. J Biol Chem (1986) 1.17
The effects of deletions in the central helix of calmodulin on enzyme activation and peptide binding. J Biol Chem (1989) 1.16
Phosphorylase kinase from rabbit skeletal muscle: identification of the calmodulin-binding subunits. Eur J Biochem (1980) 1.16
A convenient method for the preparation of primer-dependent polynucleotide phosphorylase from Micrococcus lysodeikticus. Biochem Biophys Res Commun (1967) 1.14
Agonist and antagonist properties of calmodulin fragments. J Biol Chem (1984) 1.13
Ultrastructural immunocytochemical localization of calmodulin in cultured cells. J Histochem Cytochem (1983) 1.13
Isotope-edited multidimensional NMR of calcineurin B in the presence of the non-deuterated detergent CHAPS. J Biomol NMR (1993) 1.11
The role of alpha-lactalbumin in lactose synthetase. Biochem Biophys Res Commun (1970) 1.10
The structure of the B subunit of calcineurin. Eur J Biochem (1984) 1.09
Calmodulin activates the isolated catalytic unit of brain adenylate cyclase. J Biol Chem (1981) 1.08
The proteolytic conversion of polynucleotide phosphorylase to a primer-dependent form. J Biol Chem (1969) 1.06
Interaction of 125I-labeled Ca2+-dependent regulator protein with cyclic nucleotide phosphodiesterase and its inhibitory protein. J Biol Chem (1978) 1.04
Low affinity Ca2+-binding sites of calcineurin B mediate conformational changes in calcineurin A. Biochemistry (2000) 1.04
Activation of phosphorylase kinase from rabbit skeletal muscle by calmodulin and troponin. FEBS Lett (1979) 1.03
Exocytosis induction in Paramecium tetraurelia cells by exogenous phosphoprotein phosphatase in vivo and in vitro: possible involvement of calcineurin in exocytotic membrane fusion. J Cell Biol (1987) 1.03
Calcineurin A alpha (PPP3CA), calcineurin A beta (PPP3CB) and calcineurin B (PPP3R1) are located on human chromosomes 4, 10q21-->q22 and 2p16-->p15 respectively. Cytogenet Cell Genet (1996) 0.99
Serine/threonine phosphatases in the nervous system. Curr Opin Neurobiol (1991) 0.98
Genetically engineered calmodulins differentially activate target enzymes. J Biol Chem (1986) 0.98
1H, 13C, 15N nuclear magnetic resonance backbone assignments and secondary structure of human calcineurin B. Biochemistry (1994) 0.97
Reversible and irreversible activation of cyclic nucleotide phosphodiesterase: separation of the regulatory and catalytic domains by limited proteolysis. Adv Cyclic Nucleotide Protein Phosphorylation Res (1984) 0.97
Fluorescence studies of the interaction of calmodulin with myosin light chain kinase. J Biol Chem (1981) 0.94
Specific perturbation by Ca2+ of tyrosyl residue 138 of calmodulin. J Biol Chem (1979) 0.94
Identification and quantification of calcium-binding proteins in squid axoplasm. J Neurosci (1988) 0.94
Solution structure of calmodulin and its complex with a myosin light chain kinase fragment. Cell Calcium (1992) 0.94
Polynucleotide phosphorylase of Micrococcus luteus (Micrococcus lysodeikticus). The effect of sulfhydryl compounds on the ability to catalyze the polymerization reaction. J Biol Chem (1968) 0.93
The interaction of -lactalbumin and the A protein of lactose synthetase. J Biol Chem (1972) 0.92
Reversible polymerization of histidine ammonia lyase. The role of sulfhydryl groups in the activity and polymeric state of the enzyme. J Biol Chem (1970) 0.90
Rabbit FKBP-59/HBI does not inhibit calcineurin activity in vitro. Biochem Biophys Res Commun (1994) 0.89
Volume change by density. Ribonuclease in 0-8 M guanidinium chloride. Biochemistry (1977) 0.88
Regulation of the calcium signal by calmodulin. Ciba Found Symp (1986) 0.88
Characterization of the lanthanide ion-binding properties of calcineurin-B using laser-induced luminescence spectroscopy. Biochemistry (1994) 0.87
Spurious protein activators of Bordetella pertussis adenylate cyclase. Eur J Biochem (1981) 0.86
Molecular cloning and characterization of the genes encoding the two subunits of Drosophila melanogaster calcineurin. J Biol Chem (1992) 0.86
Heteronuclear 3D NMR and isotopic labeling of calmodulin. Towards the complete assignment of the 1H NMR spectrum. Biochem Pharmacol (1990) 0.86
Purification and characterization of a novel Ca2+-binding protein (CBP-18) from bovine brain. J Biol Chem (1984) 0.86
Isolation and sequence of a cDNA clone for human calcineurin B, the Ca2+-binding subunit of the Ca2+/calmodulin-stimulated protein phosphatase. DNA (1989) 0.86
Domain II of calmodulin is involved in activation of calcineurin. FEBS Lett (1988) 0.86
Conformation-dependent nitration of the protein activator of cyclic adenosine 3',5'-monophosphate phosphodiesterase. Biochemistry (1978) 0.85
Calcium-induced sensitization of the central helix of calmodulin to proteolysis. Biochemistry (1991) 0.85
Identification of the calmodulin-regulated protein phosphatase, calcineurin, in rat pancreatic islets. Biochim Biophys Acta (1991) 0.84
Isolation of a cysteine-peptide at the active site of histidine ammonia-lyase. J Biol Chem (1972) 0.84
Calcium ion dependent covalent modification of calmodulin with norchlorpromazine isothiocyanate. Biochemistry (1983) 0.84
Interaction of calmodulin with skeletal muscle myosin light chain kinase. Biochemistry (1981) 0.82
Metal activation of histidine ammonia-lyase. Metal ion-sulfhydryl group relationship. J Biol Chem (1972) 0.82
Calcium control of muscle phosphorylase kinase through the combined action of calmodulin and troponin. Ann N Y Acad Sci (1980) 0.81
Concerted role of calmodulin and calcineurin in calcium regulation. Ann N Y Acad Sci (1980) 0.81
Characterization of a high-affinity monoclonal antibody to calcineurin whose epitope defines a new structural domain of calcineurin A. Eur J Biochem (1989) 0.80
Phenothiazine-binding and attachment sites of CAPP1-calmodulin. Biochemistry (1989) 0.80
Affinity selection of chemically modified proteins: role of lysyl residues in the binding of calmodulin to calcineurin. Biochemistry (1987) 0.80
Activation of enzymes by calmodulins containing intramolecular cross-links. Biochim Biophys Acta (1993) 0.79
The regulation of muscle phosphorylase kinase by calcium ions, calmodulin and troponin-C. Cell Calcium (1981) 0.79
The phosphorylation of calmodulin and calmodulin fragments by kinase fractions from bovine brain. Biochim Biophys Acta (1988) 0.79
Selective affinity chromatography with calmodulin fragments coupled to sepharose. J Biol Chem (1985) 0.79
A deoxyadenylate kinase activity associated with polynucleotide phosphorylase from Micrococcus luteus. Nucleic Acids Res (1976) 0.78
4-Nitro-L-histidine as a substrate for histidine ammonia-lyase: the role of beta-hydrogen acidity in the rate-limiting step. Biochem Biophys Res Commun (1979) 0.78
Histidine ammonia-lyase. The use of 4-fluorohistidine in identification of the rate-determining step. J Biol Chem (1975) 0.78