Cornea: Window to Ocular Immunology.

PubWeight™: 0.81‹?›

🔗 View Article (PMID 21789035)

Published in Curr Immunol Rev on August 01, 2011

Authors

Jerry Y Niederkorn1

Author Affiliations

1: Department of Ophthalmology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

Articles cited by this

(truncated to the top 100)

Fas ligand-induced apoptosis as a mechanism of immune privilege. Science (1995) 8.23

VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment. J Clin Invest (2004) 5.59

Lymphangiogenesis and cancer metastasis. Nat Rev Cancer (2002) 3.90

Herpes simplex virus 1 interaction with Toll-like receptor 2 contributes to lethal encephalitis. Proc Natl Acad Sci U S A (2004) 3.74

Ocular immune privilege: therapeutic opportunities from an experiment of nature. Nat Rev Immunol (2003) 3.74

Cyclophosphamide-sensitive T lymphocytes suppress the in vivo generation of antigen-specific cytotoxic T lymphocytes. J Exp Med (1977) 3.38

Effects of transforming growth factor beta on the functions of natural killer cells: depressed cytolytic activity and blunting of interferon responsiveness. J Immunol (1986) 3.29

The collaborative corneal transplantation studies (CCTS). Effectiveness of histocompatibility matching in high-risk corneal transplantation. The Collaborative Corneal Transplantation Studies Research Group. Arch Ophthalmol (1992) 3.18

IL-17 disrupts corneal barrier following desiccating stress. Mucosal Immunol (2009) 2.65

Vascular endothelial growth factor receptor-3 mediates induction of corneal alloimmunity. Nat Med (2004) 2.64

See no evil, hear no evil, do no evil: the lessons of immune privilege. Nat Immunol (2006) 2.62

Proliferative capacity of the corneal endothelium. Prog Retin Eye Res (2003) 2.46

Alternatively spliced vascular endothelial growth factor receptor-2 is an essential endogenous inhibitor of lymphatic vessel growth. Nat Med (2009) 2.39

Desiccating stress induces T cell-mediated Sjögren's Syndrome-like lacrimal keratoconjunctivitis. J Immunol (2006) 2.33

Conclusions of the corneal transplant follow up study. Collaborating Surgeons. Br J Ophthalmol (1997) 2.23

Autoimmunity in dry eye is due to resistance of Th17 to Treg suppression. J Immunol (2009) 2.19

Conjunctival T-cell subpopulations in Sjögren's and non-Sjögren's patients with dry eye. Invest Ophthalmol Vis Sci (2002) 2.19

Antiinflammatory therapy for dry eye. Am J Ophthalmol (2004) 2.12

Orthotopic corneal transplantation in mice--evidence that the immunogenetic rules of rejection do not apply. Transplantation (1992) 2.11

Dry eye-induced conjunctival epithelial squamous metaplasia is modulated by interferon-gamma. Invest Ophthalmol Vis Sci (2007) 2.09

Predominance of Th1 cells in ocular tissues during herpetic stromal keratitis. J Immunol (1992) 1.92

Regulation of delayed-type hypersensitivity. III. Effect of cyclophosphamide on the suppressor cells for delayed-type hypersensitivity to sheep erythrocytes in mice. Eur J Immunol (1978) 1.89

Immunity causing blindness: five different paths to herpes stromal keratitis. Immunol Today (1997) 1.83

Nonvascular VEGF receptor 3 expression by corneal epithelium maintains avascularity and vision. Proc Natl Acad Sci U S A (2006) 1.81

Herpetic keratitis in athymic (nude) mice. Infect Immun (1979) 1.74

The critical role of lymph nodes in corneal alloimmunization and graft rejection. Invest Ophthalmol Vis Sci (2001) 1.71

Improvement of graft prognosis in penetrating normal-risk keratoplasty by HLA class I and II matching. Eye (Lond) (2004) 1.70

CD95 ligand (FasL)-induced apoptosis is necessary for corneal allograft survival. J Clin Invest (1997) 1.69

Early events in HSV keratitis--setting the stage for a blinding disease. Microbes Infect (2005) 1.59

B7-H1-induced apoptosis as a mechanism of immune privilege of corneal allografts. J Immunol (2006) 1.52

HLA-G2, -G3, and -G4 isoforms expressed as nonmature cell surface glycoproteins inhibit NK and antigen-specific CTL cytolysis. J Immunol (2001) 1.50

Immune privilege in the anterior chamber of the eye. Crit Rev Immunol (2002) 1.44

Critical role of corneal Langerhans cells in the CD4- but not CD8-mediated immunopathology in herpes simplex virus-1-infected mouse corneas. J Immunol (1992) 1.42

HLA-G-mediated inhibition of antigen-specific cytotoxic T lymphocytes. Int Immunol (1999) 1.41

Cutting edge: role of macrophage migration inhibitory factor in inhibiting NK cell activity and preserving immune privilege. J Immunol (1998) 1.40

Efficacy and safety of cyclosporin A ophthalmic emulsion in the treatment of moderate-to-severe dry eye disease: a dose-ranging, randomized trial. The Cyclosporin A Phase 2 Study Group. Ophthalmology (2000) 1.39

HLA-G suppresses proliferation of CD4(+) T-lymphocytes. J Reprod Immunol (2000) 1.33

Anterior chamber-associated immune deviation promotes corneal allograft survival. Invest Ophthalmol Vis Sci (1996) 1.33

Herpetic stromal keratitis: an immunopathologic disease mediated by CD4+ T lymphocytes. Invest Ophthalmol Vis Sci (1992) 1.30

Role of Fas-Fas ligand interactions in the immunorejection of allogeneic mouse corneal transplants. Transplantation (1997) 1.30

Interleukin-10 treatment can suppress stromal keratitis induced by herpes simplex virus type 1. J Immunol (1994) 1.29

Immune regulation and the eye: a dangerous compromise. FASEB J (1987) 1.25

Impaired cell-mediated immunity in mice bearing healthy orthotopic corneal allografts. J Immunol (1993) 1.25

The immune privilege of corneal grafts. J Leukoc Biol (2003) 1.25

The immune privilege of corneal allografts. Transplantation (1999) 1.25

Dry eye syndromes. Chem Immunol Allergy (2007) 1.24

Innate recognition network driving herpes simplex virus-induced corneal immunopathology: role of the toll pathway in early inflammatory events in stromal keratitis. J Virol (2007) 1.24

Draining lymph nodes play an essential role in alloimmunity generated in response to high-risk corneal transplantation. Cornea (2002) 1.23

Immune mechanisms of corneal allograft rejection. Curr Eye Res (2007) 1.23

Suppression of ongoing ocular inflammatory disease by topical administration of plasmid DNA encoding IL-10. J Immunol (1997) 1.21

Corneal transplantation: how successful are we? Br J Ophthalmol (2000) 1.21

Characterization of effector T cells in dry eye disease. Invest Ophthalmol Vis Sci (2009) 1.21

Differential expression of the complement regulatory proteins in the human eye. Invest Ophthalmol Vis Sci (1993) 1.20

Role of Th17 cells in the immunopathogenesis of dry eye disease. Mucosal Immunol (2009) 1.18

The function of donor versus recipient programmed death-ligand 1 in corneal allograft survival. J Immunol (2007) 1.17

Lethal encephalitis in myeloid differentiation factor 88-deficient mice infected with herpes simplex virus 1. Am J Pathol (2005) 1.16

Immunopathology of herpes simplex virus infections. Curr Top Microbiol Immunol (1992) 1.16

The induction of anterior chamber-associated immune deviation. Chem Immunol Allergy (2007) 1.16

Expression of HLA-G in human cornea, an immune-privileged tissue. Hum Immunol (2003) 1.13

The role of natural killer cells in protection of mice against death and corneal scarring following ocular HSV-1 infection. Antiviral Res (2000) 1.11

Association of CD4+ T cell-dependent keratitis with genetic susceptibility to Pseudomonas aeruginosa ocular infection. J Immunol (1997) 1.10

Long-term survival of corneal allografts is dependent on intact CD1d-reactive NKT cells. J Immunol (2002) 1.10

Bacterial infections of the cornea (Pseudomonas aeruginosa). Chem Immunol Allergy (2007) 1.10

TRAIL: a mechanism of tumor surveillance in an immune privileged site. J Immunol (2002) 1.09

Induction of interleukin-8 gene expression is associated with herpes simplex virus infection of human corneal keratocytes but not human corneal epithelial cells. J Virol (1993) 1.09

Immunology and immunomodulation of corneal transplantation. Int Rev Immunol (2002) 1.08

Keratoconjunctivitis sicca and corneal ulcers. Cornea (1990) 1.05

The immune response to corneal allograft requires a site-specific draining lymph node. Transplantation (2002) 1.05

Ocular immunosuppressive microenvironment. Chem Immunol Allergy (2007) 1.05

Substance P regulates natural killer cell interferon-gamma production and resistance to Pseudomonas aeruginosa infection. Eur J Immunol (2005) 1.04

Cell-mediated immune tolerance to HSV-1 antigens associated with reduced susceptibility to HSV-1 corneal lesions. Invest Ophthalmol Vis Sci (1987) 0.98

Immune privilege, T-cell tolerance, and tissue-restricted autoimmunity. Hum Immunol (1997) 0.98

NKT cells are critical to initiate an inflammatory response after Pseudomonas aeruginosa ocular infection in susceptible mice. J Immunol (2007) 0.97

Role of immunity and inflammation in corneal and ocular surface disease associated with dry eye. Adv Exp Med Biol (2002) 0.97

Reproducibility of HLA-A, B, and DR typing using peripheral blood samples: results of retyping in the collaborative corneal transplantation studies. Collaborative Corneal Transplantation Studies Group (corrected) Hum Immunol (1992) 0.96

Role of TRAIL and IFN-gamma in CD4+ T cell-dependent tumor rejection in the anterior chamber of the eye. J Immunol (2003) 0.96

Expression of two molecular forms of the complement decay-accelerating factor in the eye and lacrimal gland. Invest Ophthalmol Vis Sci (1990) 0.95

The role of Fas ligand and TNF-related apoptosis-inducing ligand (TRAIL) in the ocular immune response. Chem Immunol Allergy (2007) 0.93

Isolation and characterization of a unique natural killer cell inhibitory factor present in the anterior chamber of the eye. J Immunol (1996) 0.93

Mechanisms of corneal graft rejection: the sixth annual Thygeson Lecture, presented at the Ocular Microbiology and Immunology Group meeting, October 21, 2000. Cornea (2001) 0.91

PD-L1 expression on human ocular cells and its possible role in regulating immune-mediated ocular inflammation. Invest Ophthalmol Vis Sci (2008) 0.91

Effect of alloantibodies on corneal allograft survival. Invest Ophthalmol Vis Sci (2002) 0.91

Intracameral injection of allogeneic lymphocytes enhances corneal graft survival. Invest Ophthalmol Vis Sci (1990) 0.91

A new model of experimental autoimmune keratoconjunctivitis sicca (KCS) induced in Lewis rat by the autoantigen Klk1b22. Invest Ophthalmol Vis Sci (2008) 0.90

The role of the innate immune system in the reconstituted SCID mouse model of herpetic stromal keratitis. Clin Immunol Immunopathol (1996) 0.90

Local inhibition of natural killer cell activity promotes the progressive growth of intraocular tumors. Invest Ophthalmol Vis Sci (1997) 0.89

The RMA-S lymphoma mutant; consequences of a peptide loading defect on immunological recognition and graft rejection. Int J Cancer Suppl (1991) 0.89

Feline intraocular tumors may arise from transformation of lens epithelium. Vet Pathol (2003) 0.88

Ability of intracamerally inoculated B- and T-cell enriched allogeneic lymphocytes to enhance corneal allograft survival. Int Ophthalmol (1993) 0.87

Role of natural killer cells in the rejection process of corneal allografts in rats. Transplantation (2004) 0.87

Depletion of donor-derived Langerhans cells promotes corneal allograft survival. Cornea (1996) 0.86

Characteristics of rejection of orthotopic corneal allografts in the rat. Transplantation (1988) 0.86

IL-18 contributes to host resistance against infection with Pseudomonas aeruginosa through induction of IFN-gamma production. J Immunol (2002) 0.85

Immune privilege of the eye and fetus: parallel universes? Transplantation (2005) 0.85

Activation of NK cells in mice following corneal infection with herpes simplex virus type-1. Invest Ophthalmol Vis Sci (1992) 0.85

A small molecular weight factor in aqueous humor acts on C1q to prevent antibody-dependent complement activation. Invest Ophthalmol Vis Sci (1998) 0.85

The immunology of corneal transplantation. Dev Ophthalmol (1999) 0.83

The differential effects of donor versus host Langerhans cells in the rejection of MHC-matched corneal allografts. Transplantation (1991) 0.83

Susceptibility of corneal allografts and xenografts to antibody-mediated rejection. Immunol Lett (2005) 0.82

Are corneal cells susceptible to antibody-mediated killing in corneal allograft rejection? Transpl Immunol (2003) 0.82