Published in J Am Chem Soc on August 16, 2011
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Multiplex amplification of large sets of human exons. Nat Methods (2007) 15.11
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin. PLoS Biol (2010) 11.85
Interrogating a high-density SNP map for signatures of natural selection. Genome Res (2002) 10.33
Somatic coding mutations in human induced pluripotent stem cells. Nature (2011) 9.50
Increased methylation variation in epigenetic domains across cancer types. Nat Genet (2011) 8.92
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alpha-Synuclein is phosphorylated in synucleinopathy lesions. Nat Cell Biol (2002) 6.64
Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells. Mol Cell (2011) 4.89
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Human oocytes reprogram somatic cells to a pluripotent state. Nature (2011) 4.03
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Presenilin-dependent transcriptional control of the Abeta-degrading enzyme neprilysin by intracellular domains of betaAPP and APLP. Neuron (2005) 3.83
A public resource facilitating clinical use of genomes. Proc Natl Acad Sci U S A (2012) 3.72
Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome. Nature (2011) 3.56
Impaired dopamine release and synaptic plasticity in the striatum of PINK1-deficient mice. Proc Natl Acad Sci U S A (2007) 3.50
Targeted gene correction of laminopathy-associated LMNA mutations in patient-specific iPSCs. Cell Stem Cell (2011) 3.32
Nigrostriatal dopaminergic deficits and hypokinesia caused by inactivation of the familial Parkinsonism-linked gene DJ-1. Neuron (2005) 3.30
Neuronal activity modifies the DNA methylation landscape in the adult brain. Nat Neurosci (2011) 3.27
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A novel medium access control protocol with low delay and traffic adaptivity for wireless body area networks. J Med Syst (2011) 2.17
LRRK2 regulates synaptic vesicle endocytosis. Exp Cell Res (2008) 2.09
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Decoupling suspension controller based on magnetic flux feedback. ScientificWorldJournal (2013) 2.03
Tet1 controls meiosis by regulating meiotic gene expression. Nature (2012) 2.01
Quantifying the Waddington landscape and biological paths for development and differentiation. Proc Natl Acad Sci U S A (2011) 2.00
Evolutionary history and adaptation from high-coverage whole-genome sequences of diverse African hunter-gatherers. Cell (2012) 2.00
Metabolic signatures uncover distinct targets in molecular subsets of diffuse large B cell lymphoma. Cancer Cell (2012) 1.98
Notch controls embryonic Schwann cell differentiation, postnatal myelination and adult plasticity. Nat Neurosci (2009) 1.93
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The effect of single nucleotide polymorphism identification strategies on estimates of linkage disequilibrium. Mol Biol Evol (2003) 1.93
Activation of telomerase by human cytomegalovirus. J Natl Cancer Inst (2009) 1.92
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SLC11A1 (NRAMP1) polymorphisms and tuberculosis susceptibility: updated systematic review and meta-analysis. PLoS One (2011) 1.70
PTEN-inducible kinase 1 (PINK1)/Park6 is indispensable for normal heart function. Proc Natl Acad Sci U S A (2011) 1.70
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Massively parallel polymerase cloning and genome sequencing of single cells using nanoliter microwells. Nat Biotechnol (2013) 1.69
Conditional activation of β-catenin signaling in mice leads to severe defects in intervertebral disc tissue. Arthritis Rheum (2012) 1.67
A prospective clinical study of proximal humerus fractures treated with a locking proximal humerus plate. J Orthop Trauma (2011) 1.66
A multicenter, double-blind, randomized, controlled phase III clinical trial of chicken type II collagen in rheumatoid arthritis. Arthritis Res Ther (2009) 1.65
Analysis of spatial and temporal water pollution patterns in Lake Dianchi using multivariate statistical methods. Environ Monit Assess (2009) 1.62
(α-NaYbF4:Tm(3+))/CaF2 core/shell nanoparticles with efficient near-infrared to near-infrared upconversion for high-contrast deep tissue bioimaging. ACS Nano (2012) 1.61
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Conditional inactivation of presenilin 1 prevents amyloid accumulation and temporarily rescues contextual and spatial working memory impairments in amyloid precursor protein transgenic mice. J Neurosci (2005) 1.53
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Alcohol dehydrogenase-specific T-cell responses are associated with alcohol consumption in patients with alcohol-related cirrhosis. Hepatology (2013) 1.47
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Effect of airborne contaminants on the wettability of supported graphene and graphite. Nat Mater (2013) 1.42
ROS-dependent regulation of Parkin and DJ-1 localization during oxidative stress in neurons. Hum Mol Genet (2012) 1.42
NOTCH signaling in skeletal progenitors is critical for fracture repair. J Clin Invest (2016) 1.41
Transcriptional repression of p53 by parkin and impairment by mutations associated with autosomal recessive juvenile Parkinson's disease. Nat Cell Biol (2009) 1.41
Monodisperse porous LiFePO4 microspheres for a high power Li-ion battery cathode. J Am Chem Soc (2011) 1.41
Racial/Ethnic disparities in ART adherence in the United States: findings from the MACH14 study. J Acquir Immune Defic Syndr (2012) 1.41
A Cdc20-APC ubiquitin signaling pathway regulates presynaptic differentiation. Science (2009) 1.40
Transcriptome and targetome analysis in MIR155 expressing cells using RNA-seq. RNA (2010) 1.39
Escherichia coli O86 O-antigen biosynthetic gene cluster and stepwise enzymatic synthesis of human blood group B antigen tetrasaccharide. J Am Chem Soc (2005) 1.38
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Library-free methylation sequencing with bisulfite padlock probes. Nat Methods (2012) 1.37
Anal HPV infection in HIV-positive men who have sex with men from China. PLoS One (2010) 1.37
A regulatory network involving Foxn4, Mash1 and delta-like 4/Notch1 generates V2a and V2b spinal interneurons from a common progenitor pool. Development (2007) 1.37
The expression of the Alzheimer's amyloid precursor protein-like gene is regulated by developmental timing microRNAs and their targets in Caenorhabditis elegans. Dev Biol (2008) 1.36
Parkinson's disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures. J Neural Transm (Vienna) (2011) 1.35
A stable solution-processed polymer semiconductor with record high-mobility for printed transistors. Sci Rep (2012) 1.35
Loss of leucine-rich repeat kinase 2 causes age-dependent bi-phasic alterations of the autophagy pathway. Mol Neurodegener (2012) 1.34
Absence of nigral degeneration in aged parkin/DJ-1/PINK1 triple knockout mice. J Neurochem (2009) 1.34
Parallel PWMs based fully digital transmitter with wide carrier frequency range. ScientificWorldJournal (2013) 1.34
Recent progress in understanding molecular mechanisms of cartilage degeneration during osteoarthritis. Ann N Y Acad Sci (2011) 1.34
Reduced beta-amyloid production and increased inflammatory responses in presenilin conditional knock-out mice. J Biol Chem (2004) 1.33
Hierarchical Aligned Cluster Analysis for Temporal Clustering of Human Motion. IEEE Trans Pattern Anal Mach Intell (2012) 1.31
Community-based survey of HIV transmission modes among intravenous drug users in Sichuan, China. Sex Transm Dis (2004) 1.31