PubRank

Douglas G Johns

Author PubWeight™ 32.04‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Monocyte tissue factor-dependent activation of coagulation in hypercholesterolemic mice and monkeys is inhibited by simvastatin. J Clin Invest 2012 1.51
2 Urotensin-II: a novel systemic hypertensive factor in the cat. Naunyn Schmiedebergs Arch Pharmacol 2004 1.50
3 A PCSK9-binding antibody that structurally mimics the EGF(A) domain of LDL-receptor reduces LDL cholesterol in vivo. J Lipid Res 2010 1.29
4 Effects of p38 MAPK Inhibitor on angiotensin II-dependent hypertension, organ damage, and superoxide anion production. J Cardiovasc Pharmacol 2007 1.16
5 An anti-PCSK9 antibody reduces LDL-cholesterol on top of a statin and suppresses hepatocyte SREBP-regulated genes. Int J Biol Sci 2012 1.15
6 Lysophosphatidylcholine induces inflammatory activation of human coronary artery smooth muscle cells. Mol Cell Biochem 2006 1.11
7 From 'gills to pills': urotensin-II as a regulator of mammalian cardiorenal function. Trends Pharmacol Sci 2004 1.09
8 Role of superoxide anion in regulating pressor and vascular hypertrophic response to angiotensin II. Am J Physiol Heart Circ Physiol 2002 1.08
9 Anacetrapib promotes reverse cholesterol transport and bulk cholesterol excretion in Syrian golden hamsters. J Lipid Res 2011 1.08
10 Localization of fatty acyl and double bond positions in phosphatidylcholines using a dual stage CID fragmentation coupled with ion mobility mass spectrometry. J Am Soc Mass Spectrom 2011 1.03
11 In vivo D2O labeling to quantify static and dynamic changes in cholesterol and cholesterol esters by high resolution LC/MS. J Lipid Res 2010 0.97
12 The use of stable-isotopically labeled oleic acid to interrogate lipid assembly in vivo: assessing pharmacological effects in preclinical species. J Lipid Res 2011 0.95
13 A gene expression signature that classifies human atherosclerotic plaque by relative inflammation status. Circ Cardiovasc Genet 2011 0.93
14 Identifying static and kinetic lipid phenotypes by high resolution UPLC-MS: unraveling diet-induced changes in lipid homeostasis by coupling metabolomics and fluxomics. J Proteome Res 2011 0.91
15 Quantifying cholesterol synthesis in vivo using (2)H(2)O: enabling back-to-back studies in the same subject. J Lipid Res 2011 0.89
16 Quantifying apoprotein synthesis in rodents: coupling LC-MS/MS analyses with the administration of labeled water. J Lipid Res 2012 0.88
17 Demonstration of diet-induced decoupling of fatty acid and cholesterol synthesis by combining gene expression array and 2H2O quantification. Am J Physiol Endocrinol Metab 2011 0.86
18 Regulation of the ADMA-DDAH system in endothelial cells: a novel mechanism for the sterol response element binding proteins, SREBP1c and -2. Am J Physiol Heart Circ Physiol 2009 0.86
19 Headspace analyses of ²H labeling of acetone: enabling studies of fatty acid oxidation in vivo. Anal Biochem 2010 0.86
20 Equilibration of (2)H labeling between body water and free amino acids: enabling studies of proteome synthesis. Anal Biochem 2011 0.84
21 Reconstituted HDL elicits marked changes in plasma lipids following single-dose injection in C57Bl/6 mice. J Cardiovasc Pharmacol Ther 2011 0.84
22 Deletion of the UT receptor gene results in the selective loss of urotensin-II contractile activity in aortae isolated from UT receptor knockout mice. Br J Pharmacol 2003 0.83
23 Inhibitory effects of putative peptidic urotensin-II receptor antagonists on urotensin-II-induced contraction of cat isolated respiratory smooth muscle. Eur J Pharmacol 2005 0.83
24 Small molecule activation of lecithin cholesterol acyltransferase modulates lipoprotein metabolism in mice and hamsters. Metabolism 2011 0.83
25 Use of [13C18] oleic acid and mass isotopomer distribution analysis to study synthesis of plasma triglycerides in vivo: analytical and experimental considerations. Anal Chem 2013 0.83
26 NADPH oxidase-dependent and -independent mechanisms of reported inhibitors of reactive oxygen generation. J Enzyme Inhib Med Chem 2011 0.82
27 In vivo effects of anacetrapib on preβ HDL: improvement in HDL remodeling without effects on cholesterol absorption. J Lipid Res 2013 0.81
28 Inhibition of cholesteryl ester transfer protein by anacetrapib does not impair the anti-inflammatory properties of high density lipoprotein. Biochim Biophys Acta 2012 0.81
29 Cloning and pharmacological characterization of the cat urotensin-II receptor (UT). Biochem Pharmacol 2005 0.80
30 Tracking fatty acid kinetics in distinct lipoprotein fractions in vivo: a novel high-throughput approach for studying dyslipidemia in rodent models. J Lipid Res 2012 0.79
31 Inverse relationship between LDL cholesterol and PCSK9 plasma levels in dyslipidemic cynomolgus monkeys: effects of LDL lowering by ezetimibe in the absence of statins. Atherosclerosis 2013 0.79
32 Development of a high-throughput cell-based assay for superoxide production in HL-60 cells. J Biomol Screen 2010 0.79
33 Development of lipoprotein(a) siRNAs for mechanism of action studies in non-human primate models of atherosclerosis. J Cardiovasc Transl Res 2015 0.77
34 Techniques: Cardiovascular pharmacology and drug discovery in the 21st century. Trends Pharmacol Sci 2004 0.76
35 Attenuation of Slc27a5 gene expression followed by LC-MS measurement of bile acid reconjugation using metabolomics and a stable isotope tracer strategy. J Proteome Res 2011 0.75
36 In vivo isotopically labeled atherosclerotic aorta plaques in ApoE KO mice and molecular profiling by matrix-assisted laser desorption/ionization mass spectrometric imaging. Rapid Commun Mass Spectrom 2014 0.75
37 Determination of low levels of 2H-labeling using high-resolution mass spectrometry: application in studies of lipid flux and beyond. Rapid Commun Mass Spectrom 2014 0.75
38 Quantitative analysis of orphan G protein-coupled receptor mRNAs by TaqMan Real-Time PCR: G2A and GPR4 lysophospholipid receptor expression in leukocytes and in a rat myocardial infarction-heart failure model. Methods Mol Biol 2005 0.75
39 Measuring H(2)(18)O tracer incorporation on a QQQ-MS platform provides a rapid, transferable screening tool for relative protein synthesis. J Proteome Res 2012 0.75