Published in Eur J Epidemiol on August 30, 2011
Variant of TREM2 associated with the risk of Alzheimer's disease. N Engl J Med (2012) 10.16
Systematic identification of trans eQTLs as putative drivers of known disease associations. Nat Genet (2013) 7.13
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science (2013) 4.71
Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease. Nat Genet (2014) 4.60
The Generation R Study: design and cohort update 2012. Eur J Epidemiol (2012) 2.84
Best practices and joint calling of the HumanExome BeadChip: the CHARGE Consortium. PLoS One (2013) 2.65
The Rotterdam Study: 2014 objectives and design update. Eur J Epidemiol (2013) 2.56
Projections on the number of individuals with atrial fibrillation in the European Union, from 2000 to 2060. Eur Heart J (2013) 2.17
A genome-wide association study identifies five loci influencing facial morphology in Europeans. PLoS Genet (2012) 1.91
A gene variant near ATM is significantly associated with metformin treatment response in type 2 diabetes: a replication and meta-analysis of five cohorts. Diabetologia (2012) 1.83
The Genome of the Netherlands: design, and project goals. Eur J Hum Genet (2013) 1.68
The Rotterdam Study: 2016 objectives and design update. Eur J Epidemiol (2015) 1.61
A genome-wide association study of depressive symptoms. Biol Psychiatry (2013) 1.58
Susceptibility to chronic mucus hypersecretion, a genome wide association study. PLoS One (2014) 1.52
Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function. PLoS Genet (2012) 1.52
Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus. PLoS Genet (2012) 1.49
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The Generation R Study: Biobank update 2015. Eur J Epidemiol (2014) 1.26
One risk assessment tool for cardiovascular disease, type 2 diabetes, and chronic kidney disease. Diabetes Care (2012) 1.21
High bone mineral density and fracture risk in type 2 diabetes as skeletal complications of inadequate glucose control: the Rotterdam Study. Diabetes Care (2013) 1.19
Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis. PLoS One (2013) 1.16
Methods of data collection and definitions of cardiac outcomes in the Rotterdam Study. Eur J Epidemiol (2012) 1.15
Trends in stroke incidence rates and stroke risk factors in Rotterdam, the Netherlands from 1990 to 2008. Eur J Epidemiol (2012) 1.13
Genome-wide association study meta-analysis of chronic widespread pain: evidence for involvement of the 5p15.2 region. Ann Rheum Dis (2012) 1.13
Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma. Nat Genet (2014) 1.13
Interleukin-6 receptor pathways in abdominal aortic aneurysm. Eur Heart J (2012) 1.12
Education influences the role of genetics in myopia. Eur J Epidemiol (2013) 1.10
Development and validation of a coronary risk prediction model for older U.S. and European persons in the Cardiovascular Health Study and the Rotterdam Study. Ann Intern Med (2012) 1.10
Molecular genetics and subjective well-being. Proc Natl Acad Sci U S A (2013) 1.09
Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease. Am J Clin Nutr (2013) 1.08
Genome-wide association analysis identifies six new loci associated with forced vital capacity. Nat Genet (2014) 1.07
The Rotterdam Scan Study: design and update up to 2012. Eur J Epidemiol (2011) 1.07
Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error. Am J Hum Genet (2013) 1.06
Meta-analysis investigating associations between healthy diet and fasting glucose and insulin levels and modification by loci associated with glucose homeostasis in data from 15 cohorts. Am J Epidemiol (2012) 1.03
Prediction of age-related macular degeneration in the general population: the Three Continent AMD Consortium. Ophthalmology (2013) 1.02
Harmonizing the classification of age-related macular degeneration in the three-continent AMD consortium. Ophthalmic Epidemiol (2014) 1.01
A meta-analysis of gene expression signatures of blood pressure and hypertension. PLoS Genet (2015) 0.99
The association between physical activity and dementia in an elderly population: the Rotterdam Study. Eur J Epidemiol (2013) 0.97
Lipids, lipid genes, and incident age-related macular degeneration: the three continent age-related macular degeneration consortium. Am J Ophthalmol (2014) 0.96
Comprehensive candidate gene study highlights UGT1A and BNC2 as new genes determining continuous skin color variation in Europeans. Hum Genet (2012) 0.95
Novel loci associated with usual sleep duration: the CHARGE Consortium Genome-Wide Association Study. Mol Psychiatry (2014) 0.94
Review of radiological scoring methods of osteoporotic vertebral fractures for clinical and research settings. Eur Radiol (2012) 0.93
Cerebral microbleeds and the risk of mortality in the general population. Eur J Epidemiol (2013) 0.93
Improving accuracy of rare variant imputation with a two-step imputation approach. Eur J Hum Genet (2014) 0.92
Common carotid intima-media thickness does not add to Framingham risk score in individuals with diabetes mellitus: the USE-IMT initiative. Diabetologia (2013) 0.91
Genetic, physiological, and lifestyle predictors of mortality in the general population. Am J Public Health (2012) 0.90
Vitamin D and C-Reactive Protein: A Mendelian Randomization Study. PLoS One (2015) 0.90
Patterns of cognitive function in aging: the Rotterdam Study. Eur J Epidemiol (2014) 0.89
Genome-wide association study for radiographic vertebral fractures: a potential role for the 16q24 BMD locus. Bone (2014) 0.88
Population-based meta-analysis in Caucasians confirms association with COL5A1 and ZNF469 but not COL8A2 with central corneal thickness. Hum Genet (2012) 0.88
Dairy products and the risk of stroke and coronary heart disease: the Rotterdam Study. Eur J Nutr (2014) 0.87
Cerebral microbleeds are associated with the progression of ischemic vascular lesions. Cerebrovasc Dis (2014) 0.87
Analysis of rare variants in the C3 gene in patients with age-related macular degeneration. PLoS One (2014) 0.87
Studying variability in human brain aging in a population-based German cohort-rationale and design of 1000BRAINS. Front Aging Neurosci (2014) 0.86
Serum uric acid and chronic kidney disease: the role of hypertension. PLoS One (2013) 0.86
Personalized prediction of lifetime benefits with statin therapy for asymptomatic individuals: a modeling study. PLoS Med (2012) 0.86
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A survey on computer aided diagnosis for ocular diseases. BMC Med Inform Decis Mak (2014) 0.85
High serum thyrotropin levels are associated with current but not with incident hypertension. Thyroid (2013) 0.85
Meat consumption and its association with C-reactive protein and incident type 2 diabetes: the Rotterdam Study. Diabetes Care (2012) 0.84
Generalized estimating equations for genome-wide association studies using longitudinal phenotype data. Stat Med (2014) 0.84
Adverse outcomes of frailty in the elderly: the Rotterdam Study. Eur J Epidemiol (2014) 0.84
A serum 25-hydroxyvitamin D concentration-associated genetic variant in DHCR7 interacts with type 2 diabetes status to influence subclinical atherosclerosis (measured by carotid intima-media thickness). Diabetologia (2014) 0.83
B vitamins, homocysteine and bone health. Nutrients (2015) 0.83
Nutrient intake and risk of open-angle glaucoma: the Rotterdam Study. Eur J Epidemiol (2012) 0.83
Dissecting the relationship between high-sensitivity serum C-reactive protein and increased fracture risk: the Rotterdam Study. Osteoporos Int (2013) 0.82
A genome-wide association meta-analysis of plasma Aβ peptides concentrations in the elderly. Mol Psychiatry (2014) 0.82
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β-Adrenoceptor blockers and pulmonary function in the general population: the Rotterdam Study. Br J Clin Pharmacol (2014) 0.82
Retinopathy and risk of dementia: the Rotterdam Study. Neurology (2012) 0.80
Predictive value of updating Framingham risk scores with novel risk markers in the U.S. general population. PLoS One (2014) 0.80
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Non-steroidal anti-inflammatory drugs and the risk of atrial fibrillation: a population-based follow-up study. BMJ Open (2014) 0.80
Clopidogrel use is associated with an increased prevalence of cerebral microbleeds in a stroke-free population: the Rotterdam study. J Am Heart Assoc (2013) 0.80
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Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium. Hum Genet (2014) 0.79
High caloric intake, poor cognition and dementia: the Caerphilly Prospective Study. Eur J Epidemiol (2012) 0.79
Normal spirometry values in healthy elderly: the Rotterdam Study. Eur J Epidemiol (2013) 0.78
Association of heat shock proteins with all-cause mortality. Age (Dordr) (2012) 0.78
Low-density lipoprotein receptor mutations generate synthetic genome-wide associations. Eur J Hum Genet (2012) 0.78
Older age relates to worsening of fine motor skills: a population-based study of middle-aged and elderly persons. Front Aging Neurosci (2014) 0.78
Separate prediction of intracerebral hemorrhage and ischemic stroke. Neurology (2014) 0.78
Comparison of semi-automated and manual measurements of carotid intima-media thickening. Biomed Res Int (2014) 0.77
MRI-based cerebellar volume measurements correlate with the International Cooperative Ataxia Rating Scale score in patients with spinocerebellar degeneration or multiple system atrophy. Cerebellum Ataxias (2016) 0.77
Methylation of migraine-related genes in different tissues of the rat. PLoS One (2014) 0.77
Multicenter cohort association study of SLC2A1 single nucleotide polymorphisms and age-related macular degeneration. Mol Vis (2012) 0.76
Multi-functionality of computer-aided quantitative vertebral fracture morphometry analyses. Quant Imaging Med Surg (2013) 0.76
Optimizing the information yield of 3-D OCT in glaucoma. Invest Ophthalmol Vis Sci (2012) 0.76
Association of heat shock proteins with Parkinson's disease. Eur J Epidemiol (2011) 0.76
Controlling bias and inflation in epigenome- and transcriptome-wide association studies using the empirical null distribution. Genome Biol (2017) 0.76
The design organization test: further demonstration of reliability and validity as a brief measure of visuospatial ability. Appl Neuropsychol Adult (2013) 0.75
Novel inflammatory markers for incident pre-diabetes and type 2 diabetes: the Rotterdam Study. Eur J Epidemiol (2017) 0.75
Gene transcripts associated with muscle strength: a CHARGE meta-analysis of 7,781 persons. Physiol Genomics (2015) 0.75
Diabetes and atrial fibrillation: stratification and prevention of stroke risks. EPMA J (2014) 0.75
Social disparities in diabetes care: a general population study in Denmark. Scand J Prim Health Care (2017) 0.75
Uncompromised 10-year survival of oldest old carrying somatic mutations in DNMT3A and TET2. Blood (2016) 0.75
Evaluation of Presumably Disease Causing SCN1A Variants in a Cohort of Common Epilepsy Syndromes. PLoS One (2016) 0.75
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Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35
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Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. Eur J Epidemiol (2010) 16.24
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nat Genet (2008) 12.32
Genome-wide association study of blood pressure and hypertension. Nat Genet (2009) 11.54
Variants in MTNR1B influence fasting glucose levels. Nat Genet (2008) 10.85
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Silent brain infarcts and the risk of dementia and cognitive decline. N Engl J Med (2003) 10.61
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The Swedish personal identity number: possibilities and pitfalls in healthcare and medical research. Eur J Epidemiol (2009) 7.62
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Genome-wide meta-analyses identify multiple loci associated with smoking behavior. Nat Genet (2010) 6.68
Prevalence, incidence and lifetime risk of atrial fibrillation: the Rotterdam study. Eur Heart J (2006) 6.31
Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study. Lancet (2008) 5.89
The Rotterdam Study: objectives and design update. Eur J Epidemiol (2007) 5.78
Body mass index as a predictor of fracture risk: a meta-analysis. Osteoporos Int (2005) 5.54
Prolonged QTc interval and risk of sudden cardiac death in a population of older adults. J Am Coll Cardiol (2006) 5.39
Alcohol consumption and risk of dementia: the Rotterdam Study. Lancet (2002) 5.32
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Multiple loci associated with indices of renal function and chronic kidney disease. Nat Genet (2009) 4.78
Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function. Nat Genet (2009) 4.56
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A genome-wide association study of optic disc parameters. PLoS Genet (2010) 1.87
A new marker for osteoarthritis: cross-sectional and longitudinal approach. Arthritis Rheum (2004) 1.87
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Genome-wide association study of blood pressure and hypertension. Nat Genet (2009) 11.54
Variants in MTNR1B influence fasting glucose levels. Nat Genet (2008) 10.85
Variant of TREM2 associated with the risk of Alzheimer's disease. N Engl J Med (2012) 10.16
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism. Science (2002) 9.90
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Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study. Lancet (2008) 5.89
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New loci associated with kidney function and chronic kidney disease. Nat Genet (2010) 5.58
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet (2012) 5.48
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Alcohol consumption and risk of dementia: the Rotterdam Study. Lancet (2002) 5.32
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