Published in Nat Genet on October 16, 2011
Effects of short-course oral corticosteroid therapy in early dengue infection in Vietnamese patients: a randomized, placebo-controlled trial. Clin Infect Dis (2012) 3.06
Human genetic susceptibility to infectious disease. Nat Rev Genet (2012) 2.25
Genome-wide association study of spontaneous resolution of hepatitis C virus infection: data from multiple cohorts. Ann Intern Med (2013) 1.82
Major histocompatibility complex genomics and human disease. Annu Rev Genomics Hum Genet (2013) 1.75
Dengue in India. Indian J Med Res (2012) 1.70
Deep whole-genome sequencing of 100 southeast Asian Malays. Am J Hum Genet (2013) 1.55
Genotypic variants at 2q33 and risk of esophageal squamous cell carcinoma in China: a meta-analysis of genome-wide association studies. Hum Mol Genet (2012) 1.28
Common variants in the HLA-DRB1-HLA-DQA1 HLA class II region are associated with susceptibility to visceral leishmaniasis. Nat Genet (2013) 1.15
Epidemiological risk factors associated with high global frequency of inapparent dengue virus infections. Front Immunol (2014) 1.13
Enhanced humoral and HLA-A2-restricted dengue virus-specific T-cell responses in humanized BLT NSG mice. Immunology (2012) 1.12
Genetic variants of MICB and PLCE1 and associations with non-severe dengue. PLoS One (2013) 1.10
Leukocyte immunoglobulin-like receptor B1 is critical for antibody-dependent dengue. Proc Natl Acad Sci U S A (2014) 1.00
Variation at HLA-DRB1 is associated with resistance to enteric fever. Nat Genet (2014) 0.99
Sequential dengue virus infections detected in active and passive surveillance programs in Thailand, 1994-2010. BMC Public Health (2015) 0.99
Flaviviruses, an expanding threat in public health: focus on dengue, West Nile, and Japanese encephalitis virus. J Neurovirol (2014) 0.98
Long-term safety assessment of live attenuated tetravalent dengue vaccines: deliberations from a WHO technical consultation. Vaccine (2013) 0.95
Clinical evaluation of dengue and identification of risk factors for severe disease: protocol for a multicentre study in 8 countries. BMC Infect Dis (2016) 0.93
TM4SF20 ancestral deletion and susceptibility to a pediatric disorder of early language delay and cerebral white matter hyperintensities. Am J Hum Genet (2013) 0.93
Lovastatin for adult patients with dengue: protocol for a randomised controlled trial. Trials (2012) 0.93
ABCC5, a gene that influences the anterior chamber depth, is associated with primary angle closure glaucoma. PLoS Genet (2014) 0.92
Targeting host factors to treat West Nile and dengue viral infections. Viruses (2014) 0.92
Review article: Research on dengue during World War II revisited. Am J Trop Med Hyg (2014) 0.91
NK Cells during Dengue Disease and Their Recognition of Dengue Virus-Infected cells. Front Immunol (2014) 0.90
Is diabetes a risk factor for a severe clinical presentation of dengue?--review and meta-analysis. PLoS Negl Trop Dis (2015) 0.90
Dogma in classifying dengue disease. Am J Trop Med Hyg (2013) 0.89
Distinct genetic association at the PLCE1 locus with oesophageal squamous cell carcinoma in the South African population. Carcinogenesis (2012) 0.87
JC polyomavirus infection is strongly controlled by human leucocyte antigen class II variants. PLoS Pathog (2014) 0.86
Ancestry, admixture and fitness in Colombian genomes. Sci Rep (2015) 0.85
Dengue in travelers: kinetics of viremia and NS1 antigenemia and their associations with clinical parameters. PLoS One (2013) 0.84
Genetic susceptibility to Chagas disease: an overview about the infection and about the association between disease and the immune response genes. Biomed Res Int (2013) 0.84
A replication study confirms the association of GWAS-identified SNPs at MICB and PLCE1 in Thai patients with dengue shock syndrome. BMC Med Genet (2014) 0.83
Recent advances in understanding dengue. F1000Res (2016) 0.82
A polymorphism in human CD1A is associated with susceptibility to tuberculosis. Genes Immun (2014) 0.82
PLCE1 mRNA and protein expression and survival of patients with esophageal squamous cell carcinoma and gastric adenocarcinoma. Cancer Epidemiol Biomarkers Prev (2014) 0.81
Fight against dengue in India: progresses and challenges. Parasitol Res (2013) 0.80
Tackling dengue fever: Current status and challenges. Virol J (2015) 0.79
Dengue human infection models supporting drug development. J Infect Dis (2014) 0.79
Interaction of a dengue virus NS1-derived peptide with the inhibitory receptor KIR3DL1 on natural killer cells. Clin Exp Immunol (2015) 0.79
Common polymorphisms in the CD43 gene region are associated with tuberculosis disease and mortality. Am J Respir Cell Mol Biol (2015) 0.79
Antibody-dependent enhancement of dengue virus infection inhibits RLR-mediated Type-I IFN-independent signalling through upregulation of cellular autophagy. Sci Rep (2016) 0.78
Madariaga virus infection associated with a case of acute disseminated encephalomyelitis. Am J Trop Med Hyg (2015) 0.77
Revealing the molecular signatures of host-pathogen interactions. Genome Biol (2011) 0.77
Host genetic variants and gene expression patterns associated with Epstein-Barr virus copy number in lymphoblastoid cell lines. PLoS One (2014) 0.77
Insights into the molecular evolution of Dengue virus type 4 in Puerto Rico over two decades of emergence. Virus Res (2015) 0.76
Host genomics in infectious diseases. Infect Chemother (2013) 0.76
Clinical outcome and genetic differences within a monophyletic Dengue virus type 2 population. PLoS One (2015) 0.76
DenguePredict: An Integrated Drug Repositioning Approach towards Drug Discovery for Dengue. AMIA Annu Symp Proc (2015) 0.76
Association of FcγRIIa Polymorphism with Clinical Outcome of Dengue Infection: First Insight from Pakistan. Am J Trop Med Hyg (2015) 0.76
Micronutrients and dengue. Am J Trop Med Hyg (2014) 0.76
PLCε1 regulates SDF-1α-induced lymphocyte adhesion and migration to sites of inflammation. Proc Natl Acad Sci U S A (2017) 0.75
A polymorphism in human MR1 is associated with mRNA expression and susceptibility to tuberculosis. Genes Immun (2016) 0.75
Discovery and Validation of Prognostic Biomarker Models to Guide Triage among Adult Dengue Patients at Early Infection. PLoS One (2016) 0.75
Hypoxia enhances antibody-dependent dengue virus infection. EMBO J (2017) 0.75
Circulating levels of soluble MICB in infants with symptomatic primary dengue virus infections. PLoS One (2014) 0.75
Polymorphisms of Transporter Associated with Antigen Presentation, Tumor Necrosis Factor-α and Interleukin-10 and their Implications for Protection and Susceptibility to Severe Forms of Dengue Fever in Patients in Sri Lanka. J Glob Infect Dis (2016) 0.75
In silico transcriptional regulation and functional analysis of dengue shock syndrome associated SNPs in PLCE1 and MICB genes. Funct Integr Genomics (2016) 0.75
Japanese Encephalitis Virus Exploits Dopamine D2 Receptor-phospholipase C to Target Dopaminergic Human Neuronal Cells. Front Microbiol (2017) 0.75
OSBPL10, RXRA and lipid metabolism confer African-ancestry protection against dengue haemorrhagic fever in admixed Cubans. PLoS Pathog (2017) 0.75
Genomics and infectious disease: a call to identify the ethical, legal and social implications for public health and clinical practice. Genome Med (2014) 0.75
Genomic approaches for understanding dengue: insights from the virus, vector, and host. Genome Biol (2016) 0.75
The MHC locus and genetic susceptibility to autoimmune and infectious diseases. Genome Biol (2017) 0.75
Genetic variants of MICB and PLCE1 and associations with the laboratory features of dengue. BMC Infect Dis (2017) 0.75
PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet (2007) 209.92
Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics (2004) 125.23
Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet (2006) 115.71
Dengue and dengue hemorrhagic fever. Clin Microbiol Rev (1998) 19.59
Dengue viremia titer, antibody response pattern, and virus serotype correlate with disease severity. J Infect Dis (2000) 11.44
A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1). Nat Genet (2009) 8.39
Positional cloning uncovers mutations in PLCE1 responsible for a nephrotic syndrome variant that may be reversible. Nat Genet (2006) 5.29
Differing influences of virus burden and immune activation on disease severity in secondary dengue-3 virus infections. J Infect Dis (2002) 4.67
Genome-wide association identifies multiple ulcerative colitis susceptibility loci. Nat Genet (2010) 4.65
Epidemiology of inapparent and symptomatic acute dengue virus infection: a prospective study of primary school children in Kamphaeng Phet, Thailand. Am J Epidemiol (2002) 4.62
Spatial and temporal clustering of dengue virus transmission in Thai villages. PLoS Med (2008) 3.59
Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma. Nat Genet (2011) 3.19
Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis. Nat Genet (2011) 3.06
Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3. Nat Genet (2010) 2.96
Genetic model testing and statistical power in population-based association studies of quantitative traits. Genet Epidemiol (2007) 2.95
Trends in patterns of dengue transmission over 4 years in a pediatric cohort study in Nicaragua. J Infect Dis (2010) 2.80
Determinants of inapparent and symptomatic dengue infection in a prospective study of primary school children in Kamphaeng Phet, Thailand. PLoS Negl Trop Dis (2011) 2.78
Interactions of human NKG2D with its ligands MICA, MICB, and homologs of the mouse RAE-1 protein family. Immunogenetics (2001) 2.43
A variant in the CD209 promoter is associated with severity of dengue disease. Nat Genet (2005) 2.31
A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population. Nat Genet (2009) 2.26
HLA-A and -B allele associations with secondary dengue virus infections correlate with disease severity and the infecting viral serotype in ethnic Thais. Tissue Antigens (2002) 2.18
Epidemiological factors associated with dengue shock syndrome and mortality in hospitalized dengue patients in Ho Chi Minh City, Vietnam. Am J Trop Med Hyg (2011) 2.17
Seroprevalence of dengue antibodies, annual incidence and risk factors among children in southern Vietnam. Trop Med Int Health (2005) 1.95
Epidemiology of dengue and dengue hemorrhagic fever in a cohort of adults living in Bandung, West Java, Indonesia. Am J Trop Med Hyg (2005) 1.84
Strong HLA class I--restricted T cell responses in dengue hemorrhagic fever: a double-edged sword? J Infect Dis (2001) 1.79
NKG2D ligands: key targets of the immune response. Trends Immunol (2008) 1.71
Dengue virus infections and maternal antibody decay in a prospective birth cohort study of Vietnamese infants. J Infect Dis (2009) 1.57
Susceptibility to dengue hemorrhagic fever in vietnam: evidence of an association with variation in the vitamin d receptor and Fc gamma receptor IIa genes. Am J Trop Med Hyg (2002) 1.55
The activating NKG2D receptor assembles in the membrane with two signaling dimers into a hexameric structure. Proc Natl Acad Sci U S A (2005) 1.54
A prospective cohort study of dengue infection in schoolchildren in Long Xuyen, Viet Nam. Trans R Soc Trop Med Hyg (2010) 1.51
The early whole-blood transcriptional signature of dengue virus and features associated with progression to dengue shock syndrome in Vietnamese children and young adults. J Virol (2010) 1.47
TNF and LTA gene, allele, and extended HLA haplotype associations with severe dengue virus infection in ethnic Thais. J Infect Dis (2009) 1.06
The global distribution and burden of dengue. Nature (2013) 27.92
Oseltamivir resistance during treatment of influenza A (H5N1) infection. N Engl J Med (2005) 15.53
Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia. Nat Med (2006) 14.21
Avian influenza A (H5N1) infection in humans. N Engl J Med (2005) 12.95
TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study. N Engl J Med (2007) 12.24
Avian influenza A (H5N1) in 10 patients in Vietnam. N Engl J Med (2004) 11.31
Dengue. N Engl J Med (2012) 10.45
Dengue: a continuing global threat. Nat Rev Microbiol (2010) 9.96
Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial. Lancet (2010) 8.52
Genomewide association study of leprosy. N Engl J Med (2009) 8.17
Fatal avian influenza A (H5N1) in a child presenting with diarrhea followed by coma. N Engl J Med (2005) 6.47
Normal gut microbiota modulates brain development and behavior. Proc Natl Acad Sci U S A (2011) 6.16
Hemofiltration and peritoneal dialysis in infection-associated acute renal failure in Vietnam. N Engl J Med (2002) 5.24
Evolutionary history of Salmonella typhi. Science (2006) 5.00
RNA viral community in human feces: prevalence of plant pathogenic viruses. PLoS Biol (2006) 4.93
Genome-wide association identifies multiple ulcerative colitis susceptibility loci. Nat Genet (2010) 4.65
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. Nat Genet (2012) 4.46
Genome-wide and fine-resolution association analysis of malaria in West Africa. Nat Genet (2009) 4.30
A study of typhoid fever in five Asian countries: disease burden and implications for controls. Bull World Health Organ (2008) 4.11
The influence of host and bacterial genotype on the development of disseminated disease with Mycobacterium tuberculosis. PLoS Pathog (2008) 3.79
Dihydroartemisinin-piperaquine against multidrug-resistant Plasmodium falciparum malaria in Vietnam: randomised clinical trial. Lancet (2004) 3.72
The WHO dengue classification and case definitions: time for a reassessment. Lancet (2006) 3.69
The lta4h locus modulates susceptibility to mycobacterial infection in zebrafish and humans. Cell (2010) 3.64
Prophylactic and therapeutic efficacy of human monoclonal antibodies against H5N1 influenza. PLoS Med (2007) 3.63
Adjunctive Dexamethasone in HIV-Associated Cryptococcal Meningitis. N Engl J Med (2016) 3.59
Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections. Cell (2012) 3.54
The human immune response to Dengue virus is dominated by highly cross-reactive antibodies endowed with neutralizing and enhancing activity. Cell Host Microbe (2010) 3.48
Variations in the age-specific curves of human papillomavirus prevalence in women worldwide. Int J Cancer (2006) 3.38
Diagnostic accuracy of NS1 ELISA and lateral flow rapid tests for dengue sensitivity, specificity and relationship to viraemia and antibody responses. PLoS Negl Trop Dis (2009) 3.30
Streptococcus suis meningitis in adults in Vietnam. Clin Infect Dis (2008) 3.18
In vivo susceptibility of Plasmodium falciparum to artesunate in Binh Phuoc Province, Vietnam. Malar J (2012) 3.13
Effects of short-course oral corticosteroid therapy in early dengue infection in Vietnamese patients: a randomized, placebo-controlled trial. Clin Infect Dis (2012) 3.06
Evaluation of diagnostic tests: dengue. Nat Rev Microbiol (2010) 2.91
Clinical features of human influenza A (H5N1) infection in Vietnam: 2004-2006. Clin Infect Dis (2009) 2.89
Patterns of host genome-wide gene transcript abundance in the peripheral blood of patients with acute dengue hemorrhagic fever. J Infect Dis (2007) 2.89
The epidemiology of respiratory syncytial virus lower respiratory tract infections in children less than 5 years of age in Indonesia. Pediatr Infect Dis J (2011) 2.82
In vivo assessment of drug efficacy against Plasmodium falciparum malaria: duration of follow-up. Antimicrob Agents Chemother (2004) 2.77
Phylogenetic relationships and differential selection pressures among genotypes of dengue-2 virus. Virology (2002) 2.75
Genomic epidemiology of a dengue virus epidemic in urban Singapore. J Virol (2009) 2.74
Antimicrobial drug resistance of Salmonella enterica serovar typhi in asia and molecular mechanism of reduced susceptibility to the fluoroquinolones. Antimicrob Agents Chemother (2007) 2.73
A common human TLR1 polymorphism regulates the innate immune response to lipopeptides. Eur J Immunol (2007) 2.71
Altitude Sickness in Climbers and Efficacy of NSAIDs Trial (ASCENT): randomized, controlled trial of ibuprofen versus placebo for prevention of altitude illness. Wilderness Environ Med (2012) 2.70
Meta-analysis identifies common variants associated with body mass index in east Asians. Nat Genet (2012) 2.70
Multicentre prospective study on dengue classification in four South-east Asian and three Latin American countries. Trop Med Int Health (2011) 2.60
Into the eye of the cytokine storm. Microbiol Mol Biol Rev (2012) 2.58
Transparent development of the WHO rapid advice guidelines. PLoS Med (2007) 2.57
Gatifloxacin versus chloramphenicol for uncomplicated enteric fever: an open-label, randomised, controlled trial. Lancet Infect Dis (2011) 2.54
Antigenic fingerprinting of H5N1 avian influenza using convalescent sera and monoclonal antibodies reveals potential vaccine and diagnostic targets. PLoS Med (2009) 2.47
A genome-wide association study identifies novel and functionally related susceptibility Loci for Kawasaki disease. PLoS Genet (2009) 2.45
Progress towards a dengue vaccine. Lancet Infect Dis (2009) 2.45
The influence of HIV infection on clinical presentation, response to treatment, and outcome in adults with Tuberculous meningitis. J Infect Dis (2005) 2.38
Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia. Nat Genet (2013) 2.36
Clinical diagnosis and assessment of severity of confirmed dengue infections in Vietnamese children: is the world health organization classification system helpful? Am J Trop Med Hyg (2004) 2.33
Multi-country evaluation of the sensitivity and specificity of two commercially-available NS1 ELISA assays for dengue diagnosis. PLoS Negl Trop Dis (2010) 2.33
Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease. Nat Genet (2010) 2.32
Policy: An intergovernmental panel on antimicrobial resistance. Nature (2014) 2.22
Epidemiological factors associated with dengue shock syndrome and mortality in hospitalized dengue patients in Ho Chi Minh City, Vietnam. Am J Trop Med Hyg (2011) 2.17
Emergence of the Asian 1 genotype of dengue virus serotype 2 in viet nam: in vivo fitness advantage and lineage replacement in South-East Asia. PLoS Negl Trop Dis (2010) 2.17
High-throughput genotyping of Salmonella enterica serovar Typhi allowing geographical assignment of haplotypes and pathotypes within an urban District of Jakarta, Indonesia. J Clin Microbiol (2008) 2.14
Serologic survey of pandemic (H1N1) 2009 virus, Guangxi Province, China. Emerg Infect Dis (2009) 2.13
Early Dengue infection and outcome study (EDEN) - study design and preliminary findings. Ann Acad Med Singapore (2006) 2.12
Diagnosis of childhood tuberculosis and host RNA expression in Africa. N Engl J Med (2014) 2.12
Liver involvement associated with dengue infection in adults in Vietnam. Am J Trop Med Hyg (2010) 2.10
Clinical characteristics of Dengue shock syndrome in Vietnamese children: a 10-year prospective study in a single hospital. Clin Infect Dis (2013) 2.08
Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. Nat Genet (2012) 2.05
Population-level antibody estimates to novel influenza A/H7N9. J Infect Dis (2013) 2.03
Usefulness and applicability of the revised dengue case classification by disease: multi-centre study in 18 countries. BMC Infect Dis (2011) 2.03
Randomized controlled comparison of ofloxacin, azithromycin, and an ofloxacin-azithromycin combination for treatment of multidrug-resistant and nalidixic acid-resistant typhoid fever. Antimicrob Agents Chemother (2006) 2.01
Smoking and human papillomavirus infection: pooled analysis of the International Agency for Research on Cancer HPV Prevalence Surveys. Int J Epidemiol (2008) 2.00
Decision tree algorithms predict the diagnosis and outcome of dengue fever in the early phase of illness. PLoS Negl Trop Dis (2008) 1.99
Genome-wide association study identifies FCGR2A as a susceptibility locus for Kawasaki disease. Nat Genet (2011) 1.97
Comparison of two dengue NS1 rapid tests for sensitivity, specificity and relationship to viraemia and antibody responses. BMC Infect Dis (2010) 1.97