Acute respiratory distress syndrome leads to reduced ratio of ACE/ACE2 activities and is prevented by angiotensin-(1-7) or an angiotensin II receptor antagonist.

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Published in J Pathol on October 18, 2011

Authors

Roelie M Wösten-van Asperen1, René Lutter, Patricia A Specht, Gert N Moll, Job B van Woensel, Chris M van der Loos, Harry van Goor, Jelena Kamilic, Sandrine Florquin, Albert P Bos

Author Affiliations

1: Department of Paediatric Intensive Care, Emma Children's Hospital/Academic Medical Centre, Amsterdam, The Netherlands. r.m.vanasperen@amc.uva.nl

Associated clinical trials:

Apelin; ACE2 and Biomarkers of Alveolar-capillary Permeability in SARS-cov-2 (COVID-19). (APEL-COVID) | NCT04632732

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