PubRank

W N Chia

Author PubWeight™ 17.98‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A specific, highly active malate dehydrogenase by redesign of a lactate dehydrogenase framework. Science 1988 2.63
2 Cloning, expression and complete nucleotide sequence of the Bacillus stearothermophilus L-lactate dehydrogenase gene. Gene 1986 1.76
3 Site-directed mutagenesis reveals role of mobile arginine residue in lactate dehydrogenase catalysis. Nature 1987 1.43
4 An investigation of the contribution made by the carboxylate group of an active site histidine-aspartate couple to binding and catalysis in lactate dehydrogenase. Biochemistry 1988 1.25
5 The use of genetically engineered tryptophan to identify the movement of a domain of B. stearothermophilus lactate dehydrogenase with the process which limits the steady-state turnover of the enzyme. Biochem Biophys Res Commun 1988 1.18
6 A strong carboxylate-arginine interaction is important in substrate orientation and recognition in lactate dehydrogenase. Biochim Biophys Acta 1987 1.05
7 Designs for a broad substrate specificity keto acid dehydrogenase. Biochemistry 1990 1.00
8 Detection and characterization of intermediates in the folding of large proteins by the use of genetically inserted tryptophan probes. Biochemistry 1991 0.97
9 Key residues in the allosteric transition of Bacillus stearothermophilus pyruvate kinase identified by site-directed mutagenesis. J Mol Biol 1992 0.91
10 A single amino acid substitution deregulates a bacterial lactate dehydrogenase and stabilizes its tetrameric structure. Biochim Biophys Acta 1987 0.90
11 Mapping motion in large proteins by single tryptophan probes inserted by site-directed mutagenesis: lactate dehydrogenase. Biochem Soc Trans 1987 0.86
12 The importance of arginine 171 in substrate binding by Bacillus stearothermophilus lactate dehydrogenase. Biochem Biophys Res Commun 1987 0.86
13 The engineering of a more thermally stable lactate dehydrogenase by reduction of the area of a water-accessible hydrophobic surface. Biochim Biophys Acta 1987 0.84
14 Rational construction of a 2-hydroxyacid dehydrogenase with new substrate specificity. Biochem Biophys Res Commun 1987 0.83
15 Expression of the copy DNA for human A4 and B4 L-lactate dehydrogenases in Escherichia coli. Biochim Biophys Acta 1990 0.77
16 The use of site-directed mutagenesis and time-resolved fluorescence spectroscopy to assign the fluorescence contributions of individual tryptophan residues in Bacillus stearothermophilus lactate dehydrogenase. Biochim Biophys Acta 1987 0.77