Published in J Invest Dermatol on November 17, 2011
Key role of CRF in the skin stress response system. Endocr Rev (2013) 1.77
Increased serum baseline tryptase levels and extensive skin involvement are predictors for the severity of mast cell activation episodes in children with mastocytosis. Allergy (2012) 1.66
CRF induces intestinal epithelial barrier injury via the release of mast cell proteases and TNF-α. PLoS One (2012) 1.01
Synthesis, F-18 radiolabeling, and microPET evaluation of 3-(2,4-dichlorophenyl)-N-alkyl-N-fluoroalkyl-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amines as ligands of the corticotropin-releasing factor type-1 (CRF1) receptor. Bioorg Med Chem (2015) 0.91
Novel identified receptors on mast cells. Front Immunol (2012) 0.88
Role of Corticotropin-releasing Factor in Gastrointestinal Permeability. J Neurogastroenterol Motil (2015) 0.87
Psychological Stress and the Cutaneous Immune Response: Roles of the HPA Axis and the Sympathetic Nervous System in Atopic Dermatitis and Psoriasis. Dermatol Res Pract (2012) 0.85
Neuropeptide substance P and the immune response. Cell Mol Life Sci (2016) 0.84
Mast cell adenosine receptors function: a focus on the a3 adenosine receptor and inflammation. Front Immunol (2012) 0.83
Neurotensin and CRH interactions augment human mast cell activation. PLoS One (2012) 0.82
Chronic stress suppresses the expression of cutaneous hypothalamic-pituitary-adrenocortical axis elements and melanogenesis. PLoS One (2014) 0.80
Increased serum CRH levels with decreased skin CRHR-1 gene expression in psoriasis and atopic dermatitis. J Allergy Clin Immunol (2012) 0.80
Neuropeptides CRH, SP, HK-1, and Inflammatory Cytokines IL-6 and TNF Are Increased in Serum of Patients with Fibromyalgia Syndrome, Implicating Mast Cells. J Pharmacol Exp Ther (2016) 0.76
Stress-induced mast cell activation in glabrous and hairy skin. Mediators Inflamm (2014) 0.76
Neurokinin 1 receptor blockade in the medial amygdala attenuates alcohol drinking in rats with innate anxiety but not in Wistar rats. Br J Pharmacol (2015) 0.75
Extract of Polygala tenuifolia Alleviates Stress-Exacerbated Atopy-Like Skin Dermatitis through the Modulation of Protein Kinase A and p38 Mitogen-Activated Protein Kinase Signaling Pathway. Int J Mol Sci (2017) 0.75
Hair and stress: A pilot study of hair and cytokine balance alteration in healthy young women under major exam stress. PLoS One (2017) 0.75
Unlocking the stress-allergy puzzle: need for a more comprehensive stress model. Ann Allergy Asthma Immunol (2014) 0.75
Brain and Peripheral Atypical Inflammatory Mediators Potentiate Neuroinflammation and Neurodegeneration. Front Cell Neurosci (2017) 0.75
The hypothalamic-pituitary-adrenal axis and immune-mediated inflammation. N Engl J Med (1995) 6.17
Mast cells in the development of adaptive immune responses. Nat Immunol (2005) 4.96
The isolation of a new hypotensive peptide, neurotensin, from bovine hypothalami. J Biol Chem (1973) 3.83
Neuroendocrinology of the skin. Endocr Rev (2000) 3.34
Mast cell-orchestrated immunity to pathogens. Nat Rev Immunol (2010) 3.12
Corticotropin releasing hormone and proopiomelanocortin involvement in the cutaneous response to stress. Physiol Rev (2000) 2.98
Expression cloning of a human corticotropin-releasing-factor receptor. Proc Natl Acad Sci U S A (1993) 2.70
Synthesis, storage, and release of vascular endothelial growth factor/vascular permeability factor (VEGF/VPF) by human mast cells: implications for the biological significance of VEGF206. Mol Biol Cell (1998) 2.24
The role of substance P in inflammatory disease. J Cell Physiol (2004) 2.19
Transgenic delivery of VEGF to mouse skin leads to an inflammatory condition resembling human psoriasis. Blood (2003) 2.03
Critical role of mast cells in inflammatory diseases and the effect of acute stress. J Neuroimmunol (2004) 1.98
The effects of substance P on histamine and 5-hydroxytryptamine release in the rat. J Physiol (1982) 1.88
Differential expression of HPA axis homolog in the skin. Mol Cell Endocrinol (2006) 1.72
Corticotropin-releasing hormone induces skin mast cell degranulation and increased vascular permeability, a possible explanation for its proinflammatory effects. Endocrinology (1998) 1.71
Autocrine or paracrine inflammatory actions of corticotropin-releasing hormone in vivo. Science (1991) 1.70
Neuroimmunoendocrine circuitry of the 'brain-skin connection'. Trends Immunol (2005) 1.58
IL-33 augments substance P-induced VEGF secretion from human mast cells and is increased in psoriatic skin. Proc Natl Acad Sci U S A (2010) 1.56
Mast cells as targets of corticotropin-releasing factor and related peptides. Trends Pharmacol Sci (2004) 1.50
Angiogenesis drives psoriasis pathogenesis. Int J Exp Pathol (2009) 1.49
Differential expression of a cutaneous corticotropin-releasing hormone system. Endocrinology (2003) 1.46
Corticotropin-releasing hormone-receptor 2 is required for acute stress-induced bladder vascular permeability and release of vascular endothelial growth factor. BJU Int (2010) 1.46
The critical role of mast cells in allergy and inflammation. Ann N Y Acad Sci (2006) 1.43
Psychologic factors in psoriasis: consequences, mechanisms, and interventions. Dermatol Clin (2005) 1.36
Human mast cells express corticotropin-releasing hormone (CRH) receptors and CRH leads to selective secretion of vascular endothelial growth factor. J Immunol (2005) 1.31
Stress, symmetry, and psoriasis: possible role of neuropeptides. J Am Acad Dermatol (1986) 1.30
Neurokinin 1 receptor isoforms and the control of innate immunity. Trends Immunol (2009) 1.27
Corticotropin-releasing hormone augments proinflammatory cytokine production from macrophages in vitro and in lipopolysaccharide-induced endotoxin shock in mice. Infect Immun (2002) 1.22
Corticotropin-releasing hormone and its structurally related urocortin are synthesized and secreted by human mast cells. Endocrinology (2003) 1.14
Study of substance P and its receptor neurokinin-1 in psoriasis and their relation to chronic stress and pruritus. Arch Dermatol Res (2007) 1.11
Corticotropin-releasing hormone stimulates NF-kappaB in human epidermal keratinocytes. J Endocrinol (2004) 1.10
Mast cell involvement in murine hair growth. Dev Biol (1994) 1.06
Stress exposure modulates peptidergic innervation and degranulates mast cells in murine skin. Brain Behav Immun (2005) 1.04
On the role of the corticotropin-releasing hormone signalling system in the aetiology of inflammatory skin disorders. Br J Dermatol (2009) 1.02
Mast cell deficient and neurokinin-1 receptor knockout mice are protected from stress-induced hair growth inhibition. J Mol Med (Berl) (2005) 1.01
Mediation of systemic vascular hyperpermeability in severe psoriasis by circulating vascular endothelial growth factor. Arch Dermatol (2002) 0.97
Cloning and characterization of the human corticotropin-releasing factor-2 receptor complementary deoxyribonucleic acid. Endocrinology (1996) 0.96
Double-labeled immunofluorescence study of cutaneous nerves in psoriasis. Int J Dermatol (1998) 0.95
CRH mediates inflammation induced by lipopolysaccharide in human adult epidermal keratinocytes. J Invest Dermatol (2006) 0.94
Corticotropin releasing factor receptor 1 (CRF1) and CRF2 agonists exert an anti-inflammatory effect during the early phase of inflammation suppressing LPS-induced TNF-alpha release from macrophages via induction of COX-2 and PGE2. J Cell Physiol (2007) 0.94
VEGF is likely a key factor in the link between inflammation and angiogenesis in psoriasis: results of an immunohistochemical study. Int J Immunopathol Pharmacol (2006) 0.94
Skin corticotropin-releasing hormone receptor expression in psoriasis. J Invest Dermatol (2007) 0.92
Substance P stimulates murine epidermal keratinocyte proliferation and dermal mast cell degranulation in situ. Arch Dermatol Res (1995) 0.91
Role of substance P in stress-derived degranulation of dermal mast cells in mice. J Dermatol Sci (2006) 0.90
Corticotropin-releasing hormone triggers differentiation in HaCaT keratinocytes. Br J Dermatol (2005) 0.90
Intraepidermal nerve fiber expression of calcitonin gene-related peptide, vasoactive intestinal peptide and substance P in psoriasis. Arch Dermatol Res (1997) 0.89
Alopecia areata and affected skin CRH receptor upregulation induced by acute emotional stress. Dermatology (2001) 0.88
Association of cutaneous mast cells and sensory nerves with psychic stress in psoriasis. Psychother Psychosom (1993) 0.88
Quantitative histochemical analysis of mast cells and sensory nerves in psoriatic skin. J Pathol (1996) 0.87
Placental corticotrophin-releasing hormone and its receptors in human pregnancy and labour: still a scientific enigma. J Neuroendocrinol (2008) 0.87
Evidence for vascular endothelial growth factor (VEGF) as a modifier gene in psoriasis. J Invest Dermatol (2004) 0.86
Association of psychic stress with clinical severity and symptoms of psoriatic patients. Acta Derm Venereol (1996) 0.86
Vascular endothelial growth factor gene polymorphisms increase the risk to develop psoriasis. Exp Dermatol (2006) 0.86
Substance P induces expression of the corticotropin-releasing factor receptor 1 by activation of the neurokinin-1 receptor. Brain Res (2006) 0.86
Mast cells in psoriasis. Dermatology (1996) 0.85
Vascular endothelial growth factor 121 is the predominant isoform in psoriatic scales. Exp Dermatol (2005) 0.82
Human placenta, chorion, amnion and decidua express different variants of corticotropin-releasing factor receptor messenger RNA. Placenta (2000) 0.82
Neuropeptides and general neuronal marker in psoriasis--an immunohistochemical study. Clin Exp Dermatol (1995) 0.82
Corticotropin-releasing hormone receptor-1 and histidine decarboxylase expression in chronic urticaria. J Invest Dermatol (2005) 0.82
Vascular endothelial growth factor, vascular endothelial growth factor receptor-3 and cyclooxygenase-2 expression in psoriasis. Anal Quant Cytol Histol (2007) 0.80
Regulation of corticotropin-releasing hormone receptor-2 expression in human cord blood-derived cultured mast cells. J Mol Endocrinol (2005) 0.80
Substance P downregulates expression of the high affinity IgE receptor (FcepsilonRI) by human mast cells. J Neuroimmunol (2010) 0.78
Mg2+- and Ca2+-stimulated ATPase at the outer surface of human peripheral lymphocytes and hematopoietic cell lines. Correlation between enzyme activity and immunoglobulin secretion. Acta Physiol Scand (1976) 0.77
Mast Cells, Mastocytosis, and Related Disorders. N Engl J Med (2015) 3.90
Adverse cardiovascular events temporally associated with ma huang, an herbal source of ephedrine. Mayo Clin Proc (2002) 2.67
Mast cells and inflammation. Biochim Biophys Acta (2010) 1.91
Key role of CRF in the skin stress response system. Endocr Rev (2013) 1.77
IL-10, an inflammatory/inhibitory cytokine, but not always. Immunol Lett (2003) 1.76
Neuroimmunology of stress: skin takes center stage. J Invest Dermatol (2006) 1.72
The mast cell in interstitial cystitis: role in pathophysiology and pathogenesis. Urology (2007) 1.67
Neuroimmunoendocrine circuitry of the 'brain-skin connection'. Trends Immunol (2005) 1.58
IL-33 augments substance P-induced VEGF secretion from human mast cells and is increased in psoriatic skin. Proc Natl Acad Sci U S A (2010) 1.56
High levels of intrauterine corticotropin-releasing hormone, urocortin, tryptase, and interleukin-8 in spontaneous abortions. Endocrinology (2003) 1.52
Corticotropin-releasing hormone-receptor 2 is required for acute stress-induced bladder vascular permeability and release of vascular endothelial growth factor. BJU Int (2010) 1.46
Flavonols inhibit proinflammatory mediator release, intracellular calcium ion levels and protein kinase C theta phosphorylation in human mast cells. Br J Pharmacol (2005) 1.45
Acute stress induces cardiac mast cell activation and histamine release, effects that are increased in Apolipoprotein E knockout mice. Cardiovasc Res (2002) 1.45
Acute stress-induced seizures and loss of consciousness in a ten-year-old boy with cutaneous mastocytosis. J Clin Psychopharmacol (2002) 1.45
Chronic fatigue syndrome, mast cells, and tricyclic antidepressants. J Clin Psychopharmacol (2005) 1.44
The critical role of mast cells in allergy and inflammation. Ann N Y Acad Sci (2006) 1.43
Human mast cells express corticotropin-releasing hormone (CRH) receptors and CRH leads to selective secretion of vascular endothelial growth factor. J Immunol (2005) 1.31
Corticotropin-releasing hormone and brain mast cells regulate blood-brain-barrier permeability induced by acute stress. J Pharmacol Exp Ther (2002) 1.23
Corticotropin-releasing hormone and its structurally related urocortin are synthesized and secreted by human mast cells. Endocrinology (2003) 1.14
Brain cytokines and neuropsychiatric disorders. J Clin Psychopharmacol (2004) 1.14
TSC1/2 tumour suppressor complex maintains Drosophila germline stem cells by preventing differentiation. Development (2010) 1.13
IL-1 induces vesicular secretion of IL-6 without degranulation from human mast cells. J Immunol (2003) 1.11
Corticotropin-releasing hormone induces skin vascular permeability through a neurotensin-dependent process. Proc Natl Acad Sci U S A (2006) 1.10
Serotonin-selective reuptake inhibitors and nonsteroidal anti-inflammatory drugs--important considerations of adverse interactions especially for the treatment of myalgic encephalomyelitis/chronic fatigue syndrome. J Clin Psychopharmacol (2011) 1.09
Spectrum of mast cell activation disorders. Expert Rev Clin Immunol (2014) 1.08
Advances in therapy with antileukotriene drugs. Ann Clin Lab Sci (2004) 1.07
Mast cell tryptase: a new biomarker in patients with stable coronary artery disease. Atherosclerosis (2005) 1.05
Mitochondrial DNA and anti-mitochondrial antibodies in serum of autistic children. J Neuroinflammation (2010) 1.04
Human mast cell degranulation and preformed TNF secretion require mitochondrial translocation to exocytosis sites: relevance to atopic dermatitis. J Allergy Clin Immunol (2011) 1.02
Neurotensin is increased in serum of young children with autistic disorder. J Neuroinflammation (2010) 1.01
Role of mast cells in tumor growth. Ann Clin Lab Sci (2007) 1.01
Cytokines and other mediators in alopecia areata. Mediators Inflamm (2010) 0.99
Neuro-inflammation, blood-brain barrier, seizures and autism. J Neuroinflammation (2011) 0.97
Mast cells in allergic and inflammatory diseases. Curr Pharm Des (2012) 0.95
Effect of stress on brain inflammation and multiple sclerosis. Autoimmun Rev (2013) 0.95
Acute generalized exanthematous pustulosis (AGEP) triggered by a spider bite. Allergol Int (2009) 0.95
Mast cell activation and autism. Biochim Biophys Acta (2010) 0.95
Corticotropin-releasing hormone induces vascular endothelial growth factor release from human mast cells via the cAMP/protein kinase A/p38 mitogen-activated protein kinase pathway. Mol Pharmacol (2005) 0.94
Perinatal stress, brain inflammation and risk of autism-review and proposal. BMC Pediatr (2012) 0.94
Mercury induces inflammatory mediator release from human mast cells. J Neuroinflammation (2010) 0.94
Skin corticotropin-releasing hormone receptor expression in psoriasis. J Invest Dermatol (2007) 0.92
Contribution of stress to asthma worsening through mast cell activation. Ann Allergy Asthma Immunol (2012) 0.91
Quercetin is more effective than cromolyn in blocking human mast cell cytokine release and inhibits contact dermatitis and photosensitivity in humans. PLoS One (2012) 0.90
Regulation of IL-1-induced selective IL-6 release from human mast cells and inhibition by quercetin. Br J Pharmacol (2006) 0.90
Use of polyphenols in periodontal inflammation. Eur J Pharmacol (2013) 0.89
Mitochondria distinguish granule-stored from de novo synthesized tumor necrosis factor secretion in human mast cells. Int Arch Allergy Immunol (2012) 0.88
Mast cells squeeze the heart and stretch the gird: their role in atherosclerosis and obesity. Trends Pharmacol Sci (2011) 0.88
IL-9 induces VEGF secretion from human mast cells and IL-9/IL-9 receptor genes are overexpressed in atopic dermatitis. PLoS One (2012) 0.88
Stimulated human mast cells secrete mitochondrial components that have autocrine and paracrine inflammatory actions. PLoS One (2012) 0.88
Niacin-induced "flush" involves release of prostaglandin D2 from mast cells and serotonin from platelets: evidence from human cells in vitro and an animal model. J Pharmacol Exp Ther (2008) 0.88
IL-32 is increased along with tryptase in lesional psoriatic skin and is up-regulated by substance P in human mast cells. Eur J Dermatol (2010) 0.88
Stress-induced interleukin-6 release in mice is mast cell-dependent and more pronounced in Apolipoprotein E knockout mice. Cardiovasc Res (2003) 0.87