Published in Bioorg Med Chem on October 24, 2011
The Concise Guide to PHARMACOLOGY 2013/14: enzymes. Br J Pharmacol (2013) 5.57
Transient hypercapnia reveals an underlying cerebrovascular pathology in a murine model for HIV-1 associated neuroinflammation: role of NO-cGMP signaling and normalization by inhibition of cyclic nucleotide phosphodiesterase-5. J Neuroinflammation (2012) 0.77
Interlaboratory comparison of results of susceptibility testing with caspofungin against Candida and Aspergillus species. J Clin Microbiol (2004) 4.70
Intrathecal ziconotide in the treatment of refractory pain in patients with cancer or AIDS: a randomized controlled trial. JAMA (2004) 3.47
Best practice statement on cryosurgery for the treatment of localized prostate cancer. J Urol (2008) 2.85
Physiologically based pharmacokinetic modeling 1: predicting the tissue distribution of moderate-to-strong bases. J Pharm Sci (2005) 1.95
Treatment of scedosporiosis with voriconazole: clinical experience with 107 patients. Antimicrob Agents Chemother (2008) 1.69
Prediction of pathogenic mutations in patients with early-onset breast cancer by family history. Lancet (2003) 1.52
Candidemia in nonneutropenic critically ill patients: risk factors for non-albicans Candida spp. Crit Care Med (2008) 1.50
Differentiation of frontotemporal dementia from dementia with Lewy bodies using FP-CIT SPECT. J Neurol Neurosurg Psychiatry (2012) 1.47
IL-converting enzyme/caspase-1 inhibitor VX-765 blocks the hypersensitive response to an inflammatory stimulus in monocytes from familial cold autoinflammatory syndrome patients. J Immunol (2005) 1.38
Active surveillance for candidemia, Australia. Emerg Infect Dis (2006) 1.30
Not just little adults: candidemia epidemiology, molecular characterization, and antifungal susceptibility in neonatal and pediatric patients. Pediatrics (2009) 1.25
BRCA1, BRCA2 and TP53 mutations in very early-onset breast cancer with associated risks to relatives. Eur J Cancer (2006) 1.24
Randomised controlled trial of parent groups for child antisocial behaviour targeting multiple risk factors: the SPOKES project. J Child Psychol Psychiatry (2009) 1.19
Prediction of human pharmacokinetics from preclinical information: comparative accuracy of quantitative prediction approaches. J Clin Pharmacol (2009) 1.18
Prognostic factors in prostate cancer. Key elements in structured histopathology reporting of radical prostatectomy specimens. Pathology (2011) 1.14
Rapid identification and differentiation of Trichophyton species, based on sequence polymorphisms of the ribosomal internal transcribed spacer regions, by rolling-circle amplification. J Clin Microbiol (2008) 1.11
A randomized, double-blind, placebo-controlled study of intrathecal ziconotide in adults with severe chronic pain. J Pain Symptom Manage (2006) 1.11
A novel series of potent and selective PDE5 inhibitors with potential for high and dose-independent oral bioavailability. J Med Chem (2006) 1.08
Clonality and α-a recombination in the Australian Cryptococcus gattii VGII population--an emerging outbreak in Australia. PLoS One (2011) 1.08
Asymmetric 1,8/13,2,x-M2C2B10 14-vertex metallacarboranes by direct electrophilic insertion reactions; the VCD and BHD methods in critical analysis of cage C atom positions. Dalton Trans (2014) 1.07
Determinants of mortality in non-neutropenic ICU patients with candidaemia. Crit Care (2009) 1.06
Geographic variation in the frequency of isolation and fluconazole and voriconazole susceptibilities of Candida glabrata: an assessment from the ARTEMIS DISK Global Antifungal Surveillance Program. Diagn Microbiol Infect Dis (2010) 1.06
Telemedicine/telehealth: an international perspective. Clinical applications in telemedicine/telehealth. Telemed J E Health (2002) 1.05
Intrathecal ziconotide in the treatment of chronic nonmalignant pain: a randomized, double-blind, placebo-controlled clinical trial. Neuromodulation (2006) 1.01
Structure-based design, synthesis, and biological evaluation of 1,1-dioxoisothiazole and benzo[b]thiophene-1,1-dioxide derivatives as novel inhibitors of hepatitis C virus NS5B polymerase. Bioorg Med Chem Lett (2008) 0.97
Impact of a parenting program in a high-risk, multi-ethnic community: the PALS trial. J Child Psychol Psychiatry (2010) 0.96
Simulation of human intravenous and oral pharmacokinetics of 21 diverse compounds using physiologically based pharmacokinetic modelling. Clin Pharmacokinet (2011) 0.95
Identification of signal transduction pathways used by orphan g protein-coupled receptors. Assay Drug Dev Technol (2003) 0.94
Shaping a screening file for maximal lead discovery efficiency and effectiveness: elimination of molecular redundancy. J Chem Inf Model (2012) 0.93
Protocol for optimal detection and exclusion of a patent foramen ovale using transthoracic echocardiography with agitated saline microbubbles. Echocardiography (2006) 0.92
Concurrent epizootic hyperinfections of sea lice (predominantly Caligus chiastos) and blood flukes (Cardicola forsteri) in ranched Southern Bluefin tuna. Vet Parasitol (2010) 0.92
Metabolism: a bottleneck in in vitro toxicological test development. The report and recommendations of ECVAM workshop 54. Altern Lab Anim (2006) 0.91
Unprecedented steric deformation of ortho-carborane. Chem Commun (Camb) (2008) 0.91
Tissue distribution of basic drugs: accounting for enantiomeric, compound and regional differences amongst beta-blocking drugs in rat. J Pharm Sci (2005) 0.91
Late-onset post-traumatic Phaeoacremonium parasiticum endophthalmitis. Clin Experiment Ophthalmol (2007) 0.90
Discovery of potent & selective inhibitors of activated thrombin-activatable fibrinolysis inhibitor for the treatment of thrombosis. J Med Chem (2007) 0.90
The life cycle of Cardicola forsteri (Trematoda: Aporocotylidae), a pathogen of ranched southern bluefin tuna, Thunnus maccoyi. Int J Parasitol (2011) 0.89
Predicting penetration across the blood-brain barrier from simple descriptors and fragmentation schemes. J Chem Inf Model (2007) 0.88
How to make 8,1,2-closo-MC₂B₉ metallacarboranes. Angew Chem Int Ed Engl (2014) 0.88
Pharmacokinetics and pharmacodynamics of intrathecal ziconotide in chronic pain patients. J Clin Pharmacol (2003) 0.87
In vitro and in vivo SAR of pyrido[3,4-d]pyramid-4-ylamine based mGluR1 antagonists. Bioorg Med Chem Lett (2009) 0.86
Intrathecal ziconotide for severe chronic pain: safety and tolerability results of an open-label, long-term trial. Anesth Analg (2008) 0.85
Sodium-dependent recovery of ionised magnesium concentration following magnesium load in rat heart myocytes. Pflugers Arch (2005) 0.83
A comparative assessment of three formulations of botulinum toxin A for facial rhytides: a systematic review and meta-analyses. Syst Rev (2013) 0.83
Case studies addressing human pharmacokinetic uncertainty using a combination of pharmacokinetic simulation and alternative first in human paradigms. Xenobiotica (2011) 0.83
Cyclomyces tabacinus as a cause of deep tissue infection: the first case report. Mycoses (2006) 0.82
PD168077, a D(4) receptor agonist, reverses object recognition deficits in rats: potential role for D(4) receptor mechanisms in improving cognitive dysfunction in schizophrenia. J Psychopharmacol (2010) 0.81
All-terrain vehicles (ATVs) on the road: a serious traffic safety and public health concern. Traffic Inj Prev (2013) 0.81
The conformations of 13-vertex ML2C2B10 metallacarboranes: experimental and computational studies. J Am Chem Soc (2007) 0.81
Phase II study of autologous stem cell transplant using busulfan-melphalan chemotherapy-only conditioning followed by interferon for relapsed poor prognosis follicular non-Hodgkin lymphoma. Leuk Lymphoma (2010) 0.80
Loading rat heart myocytes with Mg2+ using low-[Na+] solutions. J Physiol (2006) 0.80
An audit of intravenous fluid prescribing and plasma electrolyte monitoring; a comparison with guidelines from the National Patient Safety Agency. Paediatr Anaesth (2008) 0.79
Single-use acupuncture needles: scanning electron-microscopy of needle-tips. Acupunct Med (2002) 0.79
Population pharmacokinetic model of the pregabalin-sildenafil interaction in rats: application of simulation to preclinical PK-PD study design. Pharm Res (2009) 0.79
Novel selective inhibitors of neutral endopeptidase for the treatment of female sexual arousal disorder. Bioorg Med Chem (2006) 0.79
Novel selective inhibitors of neutral endopeptidase for the treatment of female sexual arousal disorder. Synthesis and activity of functionalized glutaramides. J Med Chem (2006) 0.79
The effect of probe to skin contact force on Cutometer MPA 580 measurements. J Med Eng Technol (2013) 0.79
Modulation of the partition coefficient between octanol and buffer at pH 7.4 and pKa to achieve the optimum balance of blood clearance and volume of distribution for a series of tetrahydropyran histamine type 3 receptor antagonists. Drug Metab Dispos (2009) 0.79
Factors influencing regional differences in intestinal absorption of UK-343,664 in rat: possible role in dose-dependent pharmacokinetics. J Pharm Sci (2006) 0.79
Discovery of a selective small-molecule melanocortin-4 receptor agonist with efficacy in a pilot study of sexual dysfunction in humans. J Med Chem (2010) 0.79
Idiopathic diffuse dendriform pulmonary ossification in a dental technician. Pathology (2012) 0.78
Serendipity in drug-discovery: a new series of 2-(benzyloxy)benzamides as TRPM8 antagonists. Bioorg Med Chem Lett (2013) 0.78
The discovery of potent nonstructural protein 5A (NS5A) inhibitors with a unique resistance profile-Part 2. ChemMedChem (2014) 0.78
Sulfonamides as selective oestrogen receptor β agonists. Bioorg Med Chem Lett (2011) 0.78
Evaluation of metaquant microdialysis for measurement of absolute concentrations of amphetamine and dopamine in brain: a viable method for assessing pharmacokinetic profile of drugs in the brain. J Neurosci Methods (2009) 0.78
Treatment of a critically ill child with disseminated Candida glabrata with a recombinant human antibody specific for fungal heat shock protein 90 and liposomal amphotericin B, caspofungin, and voriconazole. Pediatr Crit Care Med (2008) 0.78
Rapid detection of ERG11 gene mutations in clinical Candida albicans isolates with reduced susceptibility to fluconazole by rolling circle amplification and DNA sequencing. BMC Microbiol (2009) 0.78
The discovery of potent nonstructural protein 5A (NS5A) inhibitors with a unique resistance profile-Part 1. ChemMedChem (2014) 0.78
Triazole oxytocin antagonists: Identification of an aryloxyazetidine replacement for a biaryl substituent. Bioorg Med Chem Lett (2009) 0.77
Small, non-peptide C5a receptor antagonists: part 1. Bioorg Med Chem Lett (2008) 0.77
Plate-based diversity subset screening: an efficient paradigm for high throughput screening of a large screening file. Mol Divers (2013) 0.77
Stress reactivity and family relationships in the development and treatment of endometriosis. Fertil Steril (2005) 0.77
Face mask removal in the spine-injured football player: a review. Emerg Med Serv (2002) 0.77
The design and discovery of novel amide CCR5 antagonists. Bioorg Med Chem Lett (2009) 0.77
Design and synthesis of pyridazinone-based 5-HT(2C) agonists. Bioorg Med Chem Lett (2009) 0.76
Donor-transmitted malignancy confirmed by quantitative fluorescence polymerase chain reaction genotype analysis: a rare indication for liver retransplantation. Liver Transpl (2008) 0.76
Toxicokinetics and metabolism. Altern Lab Anim (2005) 0.76
Synthesis and evaluation of N-aryl pyrrolidinones as novel anti-HIV-1 agents. Part 1. Bioorg Med Chem Lett (2006) 0.76
Cyclization of the acyl glucuronide metabolite of a neutral endopeptidase inhibitor to an electrophilic glutarimide: synthesis, reactivity, and mechanistic analysis. J Med Chem (2007) 0.76
Biosensor-based approach to the identification of protein kinase ligands with dual-site modes of action. J Biomol Screen (2011) 0.76
Non-benzimidazole containing inhibitors of respiratory syncytial virus. Bioorg Med Chem Lett (2012) 0.75
Successful treatment of phaeohyphomycotic keratitis caused by Bipolaris australiensis. Clin Experiment Ophthalmol (2008) 0.75
Nonlinear oral pharmacokinetics of the alpha-antagonist 4-amino-5-(4-fluorophenyl)-6,7-dimethoxy-2-[4-(morpholinocarbonyl)-perhydro-1,4-diazepin-1-yl]quinoline in humans: use of preclinical data to rationalize clinical observations. Drug Metab Dispos (2004) 0.75
Children and autism--Part 1--recognition and pharmacological management. Aust Fam Physician (2007) 0.75
Development of a novel program to facilitate monitoring physical health and adverse effects in children and adolescents prescribed antipsychotic medication. Australas Psychiatry (2008) 0.75
Anaplastic lymphoma kinase-positive anaplastic large cell lymphoma presenting with spontaneous splenic rupture. Pathology (2004) 0.75
Part 3: Design and synthesis of proline-derived α2δ ligands. Bioorg Med Chem Lett (2011) 0.75
The time isn't right. Nurs Stand (2008) 0.75
Counting the cost. Nurs Stand (2008) 0.75