Published in PLoS One on November 16, 2011
Updates on HIPK2: a resourceful oncosuppressor for clearing cancer. J Exp Clin Cancer Res (2012) 1.10
Post-translational control of IL-1β via the human papillomavirus type 16 E6 oncoprotein: a novel mechanism of innate immune escape mediated by the E3-ubiquitin ligase E6-AP and p53. PLoS Pathog (2013) 1.00
Isolation of three novel rat and mouse papillomaviruses and their genomic characterization. PLoS One (2012) 0.92
Protective vaccination against papillomavirus-induced skin tumors under immunocompetent and immunosuppressive conditions: a preclinical study using a natural outbred animal model. PLoS Pathog (2014) 0.90
Risk of squamous cell skin cancer after organ transplant associated with antibodies to cutaneous papillomaviruses, polyomaviruses, and TMC6/8 (EVER1/2) variants. Cancer Med (2014) 0.88
Autophosphorylation and Pin1 binding coordinate DNA damage-induced HIPK2 activation and cell death. Proc Natl Acad Sci U S A (2013) 0.88
HPV vaccination for prevention of skin cancer. Hum Vaccin Immunother (2015) 0.88
Src kinase modulates the apoptotic p53 pathway by altering HIPK2 localization. Cell Cycle (2013) 0.86
Natural history of cutaneous human papillomavirus (HPV) infection in men: the HIM study. PLoS One (2014) 0.86
Genus beta human papillomavirus E6 proteins vary in their effects on the transactivation of p53 target genes. J Virol (2014) 0.83
The transmembrane channel-like protein family and human papillomaviruses: Insights into epidermodysplasia verruciformis and progression to squamous cell carcinoma. Oncoimmunology (2014) 0.82
ShaPINg Cell Fate Upon DNA Damage: Role of Pin1 Isomerase in DNA Damage-Induced Cell Death and Repair. Front Oncol (2014) 0.80
Functional Roles of E6 and E7 Oncoproteins in HPV-Induced Malignancies at Diverse Anatomical Sites. Cancers (Basel) (2016) 0.79
Updates on Psoriasis and Cutaneous Oncology: Proceedings from the 2013 MauiDerm Meeting. J Clin Aesthet Dermatol (2013) 0.79
Eyebrow hairs from actinic keratosis patients harbor the highest number of cutaneous human papillomaviruses. BMC Infect Dis (2013) 0.77
Oncoprotein E7 from beta human papillomavirus 38 induces formation of an inhibitory complex for a subset of p53-regulated promoters. J Virol (2013) 0.77
Updates on Psoriasis and Cutaneous Oncology: Proceedings from the 2016 MauiDerm Meeting based on presentations by. J Clin Aesthet Dermatol (2016) 0.77
HIPK2 restricts SIRT1 activity upon severe DNA damage by a phosphorylation-controlled mechanism. Cell Death Differ (2015) 0.76
Homeodomain-interacting protein kinase 2 (HIPK2): a promising target for anti-cancer therapies. Oncotarget (2017) 0.75
Hyperglycemia triggers HIPK2 protein degradation. Oncotarget (2016) 0.75
Epidemiologic classification of human papillomavirus types associated with cervical cancer. N Engl J Med (2003) 31.67
Papillomaviruses and cancer: from basic studies to clinical application. Nat Rev Cancer (2002) 15.46
Classification of papillomaviruses. Virology (2004) 14.16
Classification of papillomaviruses (PVs) based on 189 PV types and proposal of taxonomic amendments. Virology (2010) 7.24
p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53. Cell (2000) 5.64
Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis. Nat Cell Biol (2002) 3.55
Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2. Nat Cell Biol (2002) 3.24
Localization of the E6-AP regions that direct human papillomavirus E6 binding, association with p53, and ubiquitination of associated proteins. Mol Cell Biol (1993) 2.91
A human osteosarcoma cell line secretes a growth factor structurally related to a homodimer of PDGF A-chains. Nature (1986) 2.58
Chapter 8: Human papillomavirus and skin cancer. J Natl Cancer Inst Monogr (2003) 2.32
Characterization of two types of human papillomaviruses in lesions of epidermodysplasia verruciformis. Proc Natl Acad Sci U S A (1978) 2.26
Role of Bak in UV-induced apoptosis in skin cancer and abrogation by HPV E6 proteins. Genes Dev (2000) 2.01
Human papillomavirus-DNA loads in actinic keratoses exceed those in non-melanoma skin cancers. J Invest Dermatol (2005) 1.94
Epidermodysplasia verruciformis as a model in studies on the role of papovaviruses in oncogenesis. Cancer Res (1972) 1.91
The E6 and E7 proteins of the cutaneous human papillomavirus type 38 display transforming properties. J Virol (2003) 1.81
A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase. Proc Natl Acad Sci U S A (1995) 1.81
HPV-associated skin disease. J Pathol (2006) 1.74
Body language: the function of PML nuclear bodies in apoptosis regulation. Cell Death Differ (2003) 1.62
Control of HIPK2 stability by ubiquitin ligase Siah-1 and checkpoint kinases ATM and ATR. Nat Cell Biol (2008) 1.60
HIPK2 represses beta-catenin-mediated transcription, epidermal stem cell expansion, and skin tumorigenesis. Proc Natl Acad Sci U S A (2007) 1.58
E6 proteins from multiple human betapapillomavirus types degrade Bak and protect keratinocytes from apoptosis after UVB irradiation. J Virol (2008) 1.54
IKKalpha controls p52/RelB at the skp2 gene promoter to regulate G1- to S-phase progression. EMBO J (2006) 1.43
HIPK2 regulates transforming growth factor-beta-induced c-Jun NH(2)-terminal kinase activation and apoptosis in human hepatoma cells. Cancer Res (2003) 1.32
E6 proteins from diverse cutaneous HPV types inhibit apoptosis in response to UV damage. Oncogene (2000) 1.31
Multicenter study of the association between betapapillomavirus infection and cutaneous squamous cell carcinoma. Cancer Res (2010) 1.30
Serum- and calcium-induced differentiation of human keratinocytes is inhibited by the E6 oncoprotein of human papillomavirus type 16. J Virol (1996) 1.20
Human papillomaviruses and non-melanoma skin cancer: basic virology and clinical manifestations. Dis Markers (2007) 1.19
Homeodomain-interacting protein kinase 2 is the ionizing radiation-activated p53 serine 46 kinase and is regulated by ATM. Cancer Res (2007) 1.16
A case-control study of betapapillomavirus infection and cutaneous squamous cell carcinoma in organ transplant recipients. Am J Transplant (2011) 1.13
Comparative analysis of the intracellular location of the high- and low-risk human papillomavirus oncoproteins. Virology (2002) 1.11
How cells switch HIPK2 on and off. Cell Death Differ (2008) 1.07
Prevalence and associated factors of betapapillomavirus infections in individuals without cutaneous squamous cell carcinoma. J Gen Virol (2009) 1.04
Genomic characterization of ten novel cutaneous human papillomaviruses from keratotic lesions of immunosuppressed patients. J Gen Virol (2011) 1.03
Regulation of homeodomain-interacting protein kinase 2 (HIPK2) effector function through dynamic small ubiquitin-related modifier-1 (SUMO-1) modification. J Biol Chem (2005) 0.93
Comparative transforming potential of different human papillomaviruses associated with non-melanoma skin cancer. Virology (2007) 0.85
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Human papillomavirus-DNA loads in actinic keratoses exceed those in non-melanoma skin cancers. J Invest Dermatol (2005) 1.94
The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte autophagy. Nat Commun (2012) 1.88
Gene expression patterns of normal human skin, actinic keratosis, and squamous cell carcinoma: a spectrum of disease progression. Arch Dermatol (2010) 1.78
Control of HIPK2 stability by ubiquitin ligase Siah-1 and checkpoint kinases ATM and ATR. Nat Cell Biol (2008) 1.60
Guidelines for the management of squamous cell carcinoma in organ transplant recipients. Dermatol Surg (2004) 1.58
Human papillomavirus-16 is the predominant type etiologically involved in penile squamous cell carcinoma. J Clin Oncol (2007) 1.53
Dynamics of component exchange at PML nuclear bodies. J Cell Sci (2008) 1.47
Human NK cells are alerted to induction of p53 in cancer cells by upregulation of the NKG2D ligands ULBP1 and ULBP2. Cancer Res (2011) 1.41
Sunscreens in organ transplant patients. Nephrol Dial Transplant (2008) 1.40
Skin changes following organ transplantation: an interdisciplinary challenge. Dtsch Arztebl Int (2014) 1.39
Multicenter study of the association between betapapillomavirus infection and cutaneous squamous cell carcinoma. Cancer Res (2010) 1.30
FLASH links the CD95 signaling pathway to the cell nucleus and nuclear bodies. EMBO J (2007) 1.26
Identification of differentially expressed genes in cutaneous squamous cell carcinoma by microarray expression profiling. Mol Cancer (2006) 1.21
The role of human papillomavirus oncoproteins E6 and E7 in apoptosis. Cancer Lett (2002) 1.20
PML is required for homeodomain-interacting protein kinase 2 (HIPK2)-mediated p53 phosphorylation and cell cycle arrest but is dispensable for the formation of HIPK domains. Cancer Res (2003) 1.19
Human papillomaviruses and non-melanoma skin cancer: basic virology and clinical manifestations. Dis Markers (2007) 1.19
Coactivator function of RIP140 for NFkappaB/RelA-dependent cytokine gene expression. Blood (2008) 1.18
Role of nuclear bodies in apoptosis signalling. Biochim Biophys Acta (2008) 1.18
Homeodomain-interacting protein kinase 2 is the ionizing radiation-activated p53 serine 46 kinase and is regulated by ATM. Cancer Res (2007) 1.16
The human papillomavirus oncoprotein E7 attenuates NF-kappa B activation by targeting the Ikappa B kinase complex. J Biol Chem (2002) 1.11
Multiple evolutionary mechanisms drive papillomavirus diversification. Mol Biol Evol (2007) 1.10
IFN-alpha-induced apoptosis in hepatocellular carcinoma involves promyelocytic leukemia protein and TRAIL independently of p53. Cancer Res (2009) 1.09
Quantifying the phylodynamic forces driving papillomavirus evolution. Mol Biol Evol (2011) 1.08
Human papillomaviruses in transplant-associated skin cancers. Dermatol Surg (2004) 1.07
Epigenetic silencing of interferon-kappa in human papillomavirus type 16-positive cells. Cancer Res (2009) 1.07
Prevalence and associated factors of betapapillomavirus infections in individuals without cutaneous squamous cell carcinoma. J Gen Virol (2009) 1.04
Apoptosis and autophagy: Regulation of apoptosis by DNA damage signalling - roles of p53, p73 and HIPK2. FEBS J (2009) 1.04
Genomic characterization of ten novel cutaneous human papillomaviruses from keratotic lesions of immunosuppressed patients. J Gen Virol (2011) 1.03
Gangliosides with O-acetylated sialic acids in tumors of neuroectodermal origin. Neurochem Res (2002) 1.01
Alterations in AP-1 and AP-1 regulatory genes during HPV-induced carcinogenesis. Cell Oncol (2008) 1.01
Clinical applicability of in vivo fluorescence confocal microscopy for noninvasive diagnosis and therapeutic monitoring of nonmelanoma skin cancer. J Biomed Opt (2008) 1.00
Identification of dysregulated genes in cutaneous squamous cell carcinoma. Oncol Rep (2006) 1.00
Post-translational control of IL-1β via the human papillomavirus type 16 E6 oncoprotein: a novel mechanism of innate immune escape mediated by the E3-ubiquitin ligase E6-AP and p53. PLoS Pathog (2013) 1.00
Current state of vitiligo therapy--evidence-based analysis of the literature. J Dtsch Dermatol Ges (2007) 0.99
Hepatitis C virus core protein inhibits tumor suppressor protein promyelocytic leukemia function in human hepatoma cells. Cancer Res (2005) 0.99
A linkage map of an F2 hybrid population of Antirrhinum majus and A. molle. Genetics (2003) 0.98
Nucleolin as activator of human papillomavirus type 18 oncogene transcription in cervical cancer. J Exp Med (2002) 0.98
PIK3CA-mediated PI3-kinase signalling is essential for HPV-induced transformation in vitro. Mol Cancer (2011) 0.98
Clinical investigations of Toll-like receptor agonists. Expert Opin Investig Drugs (2008) 0.98
Comparative epidemiology and pathogenic factors for nonmelanoma skin cancer in organ transplant patients. Dermatol Surg (2004) 0.97
Keratotic skin lesions and other risk factors are associated with skin cancer in organ-transplant recipients: a case-control study in The Netherlands, United Kingdom, Germany, France, and Italy. J Invest Dermatol (2007) 0.97
mTOR inhibitor-associated dermatologic and mucosal problems. Clin Transplant (2010) 0.97
Alternative splicing of human papillomavirus type-16 E6/E6* early mRNA is coupled to EGF signaling via Erk1/2 activation. Proc Natl Acad Sci U S A (2010) 0.96
Regulation of MCP-1 chemokine transcription by p53. Mol Cancer (2010) 0.96
Adeno-associated virus type 5 exploits two different entry pathways in human embryo fibroblasts. J Gen Virol (2009) 0.96
Selective suppression of monocyte chemoattractant protein-1 expression by human papillomavirus E6 and E7 oncoproteins in human cervical epithelial and epidermal cells. Int J Cancer (2003) 0.95
FOXO3 is a glucocorticoid receptor target and regulates LKB1 and its own expression based on cellular AMP levels via a positive autoregulatory loop. PLoS One (2012) 0.95
Gene expression of the tumour suppressor LKB1 is mediated by Sp1, NF-Y and FOXO transcription factors. PLoS One (2012) 0.94
Loss of net as repressor leads to constitutive increased c-fos transcription in cervical cancer cells. J Biol Chem (2004) 0.94
Association of human papillomavirus infections with cutaneous tumors in immunosuppressed patients. Transpl Int (2003) 0.94
Genomic characterization of the first insectivoran papillomavirus reveals an unusually long, second non-coding region and indicates a close relationship to Betapapillomavirus. J Gen Virol (2009) 0.93
Persistence of Mastomys natalensis papillomavirus in multiple organs identifies novel targets for infection. J Gen Virol (2007) 0.93
Peritumoral clefting in basal cell carcinoma: correlation of in vivo reflectance confocal microscopy and routine histology. J Cutan Pathol (2010) 0.93
HDAC inhibitors trigger apoptosis in HPV-positive cells by inducing the E2F-p73 pathway. Oncogene (2004) 0.93
Human papillomavirus load in eyebrow hair follicles and risk of cutaneous squamous cell carcinoma. Cancer Epidemiol Biomarkers Prev (2013) 0.93
Restoration of p53 expression sensitizes human papillomavirus type 16 immortalized human keratinocytes to CD95-mediated apoptosis. Oncogene (2002) 0.92
Imiquimod 2.5% and 3.75% for the treatment of actinic keratoses: results of two placebo-controlled studies of daily application to the face and balding scalp for two 3-week cycles. J Am Acad Dermatol (2010) 0.92
Isolation of three novel rat and mouse papillomaviruses and their genomic characterization. PLoS One (2012) 0.92
Isolation and genomic characterization of the first Norway rat (Rattus norvegicus) papillomavirus and its phylogenetic position within Pipapillomavirus, primarily infecting rodents. J Gen Virol (2009) 0.92
Genomic characterization of a novel human papillomavirus (HPV-117) with a high viral load in a persisting wart. Virology (2010) 0.91
Resiquimod, a topical drug for viral skin lesions and skin cancer. Expert Opin Investig Drugs (2012) 0.91
Interaction of human papillomavirus type 16 L2 with cellular proteins: identification of novel nuclear body-associated proteins. Virology (2002) 0.90
The angiogenesis inhibitor thrombospondin-1 inhibits acute cutaneous hypersensitivity reactions. J Invest Dermatol (2009) 0.90
Clinical applicability of in vivo reflectance confocal microscopy for the diagnosis of actinic keratoses. Dermatol Surg (2008) 0.89
Loss of epidermal Langerhans cells occurs in human papillomavirus alpha, gamma, and mu but not beta genus infections. J Invest Dermatol (2009) 0.89
Novel animal papillomavirus sequences and accurate phylogenetic placement. Mol Phylogenet Evol (2012) 0.89
Sp100 is important for the stimulatory effect of homeodomain-interacting protein kinase-2 on p53-dependent gene expression. Oncogene (2003) 0.89
Development of a general-primer-PCR-reverse-line-blotting system for detection of beta and gamma cutaneous human papillomaviruses. J Clin Microbiol (2005) 0.88
Autophosphorylation and Pin1 binding coordinate DNA damage-induced HIPK2 activation and cell death. Proc Natl Acad Sci U S A (2013) 0.88
Herpes simplex virus immediate-early protein ICP0 is targeted by SIAH-1 for proteasomal degradation. J Virol (2011) 0.88
HPV vaccination for prevention of skin cancer. Hum Vaccin Immunother (2015) 0.88
Interference with energy metabolism by 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside induces HPV suppression in cervical carcinoma cells and apoptosis in the absence of LKB1. Biochem J (2007) 0.87
Disturbance of tumor necrosis factor alpha-mediated beta interferon signaling in cervical carcinoma cells. J Virol (2002) 0.87
Human papillomavirus and overexpression of P16INK4a in nonmelanoma skin cancer. Dermatol Surg (2004) 0.87
A novel rodent papillomavirus isolated from anogenital lesions in its natural host. Virology (2008) 0.87
FLASH meets nuclear bodies: CD95 receptor signals via a nuclear pathway. Cell Cycle (2007) 0.87
Low incidence of new actinic keratoses after topical 5% imiquimod cream treatment: a long-term follow-up study. Arch Dermatol (2004) 0.87
Applicability of confocal laser scanning microscopy for evaluation and monitoring of cutaneous wound healing. J Biomed Opt (2012) 0.87
Longitudinal study of seroprevalence and serostability of the human polyomaviruses JCV and BKV in organ transplant recipients. J Med Virol (2012) 0.86
Histone deacetylase inhibitor-induced sensitization to TNFalpha/TRAIL-mediated apoptosis in cervical carcinoma cells is dependent on HPV oncogene expression. Int J Cancer (2010) 0.86
Enhanced death ligand-induced apoptosis in cutaneous SCC cells by treatment with diclofenac/hyaluronic acid correlates with downregulation of c-FLIP. J Invest Dermatol (2010) 0.86
Growth arrest of HPV-positive cells after histone deacetylase inhibition is independent of E6/E7 oncogene expression. Virology (2002) 0.86
HIPK2 and cancer cell resistance to therapy. Future Oncol (2008) 0.86
Regulation of p53 functions: let's meet at the nuclear bodies. Curr Opin Cell Biol (2003) 0.86
Phylogenetic analysis of beta-papillomaviruses as inferred from nucleotide and amino acid sequence data. Mol Phylogenet Evol (2006) 0.85