Use of a rapid test of pneumococcal colonization density to diagnose pneumococcal pneumonia.

PubWeight™: 1.70‹?› | Rank: Top 3%

🔗 View Article (PMC 3275757)

Published in Clin Infect Dis on December 08, 2011

Authors

W C Albrich1, S A Madhi, P V Adrian, N van Niekerk, T Mareletsi, C Cutland, M Wong, M Khoosal, A Karstaedt, P Zhao, A Deatly, M Sidhu, K U Jansen, K P Klugman

Author Affiliations

1: Respiratory and Meningeal Pathogens Research Unit, University of the Witwatersrand, Johannesburg, South Africa. werner.albrich@ksa.ch

Articles citing this

Comprehensive Molecular Testing for Respiratory Pathogens in Community-Acquired Pneumonia. Clin Infect Dis (2016) 3.58

Density interactions among Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus in the nasopharynx of young Peruvian children. Pediatr Infect Dis J (2013) 2.47

Influenza promotes pneumococcal growth during coinfection by providing host sialylated substrates as a nutrient source. Cell Host Microbe (2014) 2.26

The PneuCarriage Project: A Multi-Centre Comparative Study to Identify the Best Serotyping Methods for Examining Pneumococcal Carriage in Vaccine Evaluation Studies. PLoS Med (2015) 1.46

Influence of bacterial interactions on pneumococcal colonization of the nasopharynx. Trends Microbiol (2012) 1.33

Rates of acquisition and clearance of pneumococcal serotypes in the nasopharynges of children in Kilifi District, Kenya. J Infect Dis (2012) 1.11

Comparison of sputum and nasopharyngeal aspirate samples and of the PCR gene targets lytA and Spn9802 for quantitative PCR for rapid detection of pneumococcal pneumonia. J Clin Microbiol (2013) 1.09

Cohort profile: The study of respiratory pathogens in Andean children. Int J Epidemiol (2013) 1.07

Effect of age and vaccination with a pneumococcal conjugate vaccine on the density of pneumococcal nasopharyngeal carriage. Clin Infect Dis (2012) 1.04

Diagnosis of pneumococcal pneumonia: current pitfalls and the way forward. Infect Chemother (2013) 1.00

Detection of Streptococcus pneumoniae from Different Types of Nasopharyngeal Swabs in Children. PLoS One (2013) 0.95

Etiology of community-acquired pneumonia and diagnostic yields of microbiological methods: a 3-year prospective study in Norway. BMC Infect Dis (2015) 0.95

Optimization of Polymyxin B in Combination with Doripenem To Combat Mutator Pseudomonas aeruginosa. Antimicrob Agents Chemother (2016) 0.93

Pneumococcal colonisation density: a new marker for disease severity in HIV-infected adults with pneumonia. BMJ Open (2014) 0.93

Mechanisms of Bacterial Colonization of the Respiratory Tract. Annu Rev Microbiol (2015) 0.91

Within-host selection is limited by an effective population of Streptococcus pneumoniae during nasopharyngeal colonization. Infect Immun (2013) 0.91

Impaired innate mucosal immunity in aged mice permits prolonged Streptococcus pneumoniae colonization. Infect Immun (2013) 0.89

Density and duration of experimental human pneumococcal carriage. Clin Microbiol Infect (2014) 0.89

Development of two real-time multiplex PCR assays for the detection and quantification of eight key bacterial pathogens in lower respiratory tract infections. Clin Microbiol Infect (2015) 0.89

Macrophage migration inhibitory factor promotes clearance of pneumococcal colonization. J Immunol (2014) 0.88

Genomic load from sputum samples and nasopharyngeal swabs for diagnosis of pneumococcal pneumonia in HIV-infected adults. J Clin Microbiol (2014) 0.85

Evaluation of yield of currently available diagnostics by sample type to optimize detection of respiratory pathogens in patients with a community-acquired pneumonia. Influenza Other Respir Viruses (2013) 0.84

Population density profiles of nasopharyngeal carriage of 5 bacterial species in pre-school children measured using quantitative PCR offer potential insights into the dynamics of transmission. Hum Vaccin Immunother (2016) 0.83

Single-plex quantitative assays for the detection and quantification of most pneumococcal serotypes. PLoS One (2015) 0.83

Pneumococcal aetiology and serotype distribution in paediatric community-acquired pneumonia. PLoS One (2014) 0.79

Increased Nasopharyngeal Density and Concurrent Carriage of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis Are Associated with Pneumonia in Febrile Children. PLoS One (2016) 0.78

Is Higher Viral Load in the Upper Respiratory Tract Associated With Severe Pneumonia? Findings From the PERCH Study. Clin Infect Dis (2017) 0.78

Dried Saliva Spots: A Robust Method for Detecting Streptococcus pneumoniae Carriage by PCR. Int J Mol Sci (2016) 0.78

Risk Factors for Influenza-Associated Severe Acute Respiratory Illness Hospitalization in South Africa, 2012-2015. Open Forum Infect Dis (2017) 0.77

How best to determine causative pathogens of pneumonia. Pneumonia (Nathan) (2016) 0.76

Addressing the Analytic Challenges of Cross-Sectional Pediatric Pneumonia Etiology Data. Clin Infect Dis (2017) 0.76

A prospective study of agents associated with acute respiratory infection among young American Indian children. Pediatr Infect Dis J (2013) 0.75

Clinical and Microbiological Factors Associated with High Nasopharyngeal Pneumococcal Density in Patients with Pneumococcal Pneumonia. PLoS One (2015) 0.75

A Novel Metallo-β-Lactamase Involved in the Ampicillin Resistance of Streptococcus pneumoniae ATCC 49136 Strain. PLoS One (2016) 0.75

Multiplex urinary antigen detection for 13 Streptococcus pneumoniae serotypes improves diagnosis of pneumococcal pneumonia in South African HIV-infected adults. J Clin Microbiol (2016) 0.75

PERCH in Perspective: What Can It Teach Us About Pneumonia Etiology in Children? Clin Infect Dis (2017) 0.75

Making standards for quantitative real-time pneumococcal PCR. Biomol Detect Quantif (2014) 0.75

Pneumococcal Colonization Rates in Patients Admitted to a United Kingdom Hospital with Lower Respiratory Tract Infection: a Prospective Case-Control Study. J Clin Microbiol (2016) 0.75

Utility of oropharyngeal real-time PCR for S. pneumoniae and H. influenzae for diagnosis of pneumonia in adults. Eur J Clin Microbiol Infect Dis (2016) 0.75

Influence of the pneumococcal conjugate vaccines on the temporal variation of pneumococcal carriage and the nasal microbiota in healthy infants: a longitudinal analysis of a case-control study. Microbiome (2017) 0.75

Nasopharyngeal bacterial load as a marker for rapid and easy diagnosis of invasive pneumococcal disease in children from Mozambique. PLoS One (2017) 0.75

Articles cited by this

Streptococcus pneumoniae colonisation: the key to pneumococcal disease. Lancet Infect Dis (2004) 9.73

Defining community acquired pneumonia severity on presentation to hospital: an international derivation and validation study. Thorax (2003) 9.54

Efficacy of nine-valent pneumococcal conjugate vaccine against pneumonia and invasive pneumococcal disease in The Gambia: randomised, double-blind, placebo-controlled trial. Lancet (2005) 7.99

Epidemiologic studies of Streptococcus pneumoniae in infants: acquisition, carriage, and infection during the first 24 months of life. J Infect Dis (1980) 7.45

Evaluation and improvement of real-time PCR assays targeting lytA, ply, and psaA genes for detection of pneumococcal DNA. J Clin Microbiol (2007) 4.44

Cigarette smoking and invasive pneumococcal disease. Active Bacterial Core Surveillance Team. N Engl J Med (2000) 4.20

Using a combination of reference tests to assess the accuracy of a new diagnostic test. Stat Med (1999) 4.16

A role for Streptococcus pneumoniae in virus-associated pneumonia. Nat Med (2004) 3.49

Report from a WHO Working Group: standard method for detecting upper respiratory carriage of Streptococcus pneumoniae. Pediatr Infect Dis J (2003) 3.29

Diagnostic value of microscopic examination of Gram-stained sputum and sputum cultures in patients with bacteremic pneumococcal pneumonia. Clin Infect Dis (2004) 3.11

Nasopharyngeal carriage of Streptococcus pneumoniae in Gambian villagers. Clin Infect Dis (2006) 2.96

Aetiology, outcome, and risk factors for mortality among adults with acute pneumonia in Kenya. Lancet (2000) 2.74

Indirect effect of 7-valent pneumococcal conjugate vaccine on pneumococcal colonization among unvaccinated household members. Clin Infect Dis (2008) 2.72

Detection of bacterial DNA in cerebrospinal fluid by an assay for simultaneous detection of Neisseria meningitidis, Haemophilus influenzae, and streptococci using a seminested PCR strategy. J Clin Microbiol (1994) 2.69

Limited role of antibody in clearance of Streptococcus pneumoniae in a murine model of colonization. Infect Immun (2004) 2.53

Severity of pneumococcal pneumonia associated with genomic bacterial load. Chest (2009) 2.46

The etiology of community-acquired pneumonia in Australia: why penicillin plus doxycycline or a macrolide is the most appropriate therapy. Clin Infect Dis (2008) 2.39

Indirect effect of conjugate vaccine on adult carriage of Streptococcus pneumoniae: an explanation of trends in invasive pneumococcal disease. J Infect Dis (2006) 2.30

The descriptive epidemiology of Streptococcus pneumoniae and Haemophilus influenzae nasopharyngeal carriage in children and adults in Kilifi district, Kenya. Pediatr Infect Dis J (2008) 2.23

The contribution of smoking and exposure to tobacco smoke to Streptococcus pneumoniae and Haemophilus influenzae carriage in children and their mothers. Clin Infect Dis (2006) 2.12

Association between nasopharyngeal load of Streptococcus pneumoniae, viral coinfection, and radiologically confirmed pneumonia in Vietnamese children. Pediatr Infect Dis J (2011) 1.92

Influenza alone and in sequence with pneumonia due to Streptococcus pneumoniae in the squirrel monkey. J Infect Dis (1975) 1.88

Prospective study of etiologic agents of community-acquired pneumonia in patients with HIV infection. AIDS (2002) 1.82

PCR diagnosis of invasive candidiasis: systematic review and meta-analysis. J Clin Microbiol (2010) 1.59

Microbial etiology of community-acquired pneumonia in the adult population of 4 municipalities in eastern Finland. Clin Infect Dis (2001) 1.47

Quantitative PCR assay using sputum samples for rapid diagnosis of pneumococcal pneumonia in adult emergency department patients. J Clin Microbiol (2005) 1.41

Protection against nasopharyngeal colonization by Streptococcus pneumoniae is mediated by antigen-specific CD4+ T cells. Infect Immun (2008) 1.39

World Health Organisation definition of "radiologically-confirmed pneumonia" may under-estimate the true public health value of conjugate pneumococcal vaccines. Vaccine (2006) 1.38

Role of Streptococcus pneumoniae in hospitalization for acute community-acquired pneumonia associated with culture-confirmed Mycobacterium tuberculosis in children: a pneumococcal conjugate vaccine probe study. Pediatr Infect Dis J (2010) 1.33

Novel approaches to the identification of Streptococcus pneumoniae as the cause of community-acquired pneumonia. Clin Infect Dis (2008) 1.29

Streptococcus pneumoniae DNA load in blood as a marker of infection in patients with community-acquired pneumonia. J Clin Microbiol (2009) 1.25

Toward a quantitative DNA-based definition of pneumococcal pneumonia: a comparison of Streptococcus pneumoniae target genes, with special reference to the Spn9802 fragment. Diagn Microbiol Infect Dis (2007) 1.23

TB presenting as community-acquired pneumonia in a setting of high TB incidence and high HIV prevalence. Int J Tuberc Lung Dis (2007) 1.17

Royal Society of Tropical Medicine and Hygiene Meeting at Manson House, London, 12 December 1996. HIV and pneumococcal infection in Africa. Microbiological aspects. Trans R Soc Trop Med Hyg (1998) 1.13

Prospective multicenter study of the causative organisms of community-acquired pneumonia in adults in Japan. J Infect Chemother (2006) 1.11

Decline in microbial studies for patients with pulmonary infections. Clin Infect Dis (2004) 1.11

Estimating the proportion of pneumonia attributable to pneumococcus in Kenyan adults: latent class analysis. Epidemiology (2010) 1.03

Nasopharyngeal carriage of individual Streptococcus pneumoniae serotypes during pediatric pneumonia as a means to estimate serotype disease potential. Pediatr Infect Dis J (2011) 1.00

Haemophilus influenzae type b and Streptococcus pneumoniae as causes of pneumonia among children in Beijing, China. Emerg Infect Dis (2000) 0.92

Increased rates of intense nasopharyngeal bacterial colonization of Vietnamese children with radiological pneumonia. Tohoku J Exp Med (2007) 0.92

Usefulness of aetiological tests for guiding antibiotic therapy in community-acquired pneumonia. Int J Antimicrob Agents (2007) 0.89

Articles by these authors

A comparison of enalapril with hydralazine-isosorbide dinitrate in the treatment of chronic congestive heart failure. N Engl J Med (1991) 8.65

Nomenclature of major antimicrobial-resistant clones of Streptococcus pneumoniae defined by the pneumococcal molecular epidemiology network. J Clin Microbiol (2001) 6.66

Essential role for oncogenic Ras in tumour maintenance. Nature (1999) 6.51

Prevention of neural-tube defects with folic acid in China. China-U.S. Collaborative Project for Neural Tube Defect Prevention. N Engl J Med (1999) 6.27

Epidemiological assessment of diet: a comparison of a 7-day diary with a food frequency questionnaire using urinary markers of nitrogen, potassium and sodium. Int J Epidemiol (2001) 4.94

Epidemiology of ciprofloxacin resistance and its relationship to extended-spectrum beta-lactamase production in Klebsiella pneumoniae isolates causing bacteremia. Clin Infect Dis (2000) 4.24

Outcome of cephalosporin treatment for serious infections due to apparently susceptible organisms producing extended-spectrum beta-lactamases: implications for the clinical microbiology laboratory. J Clin Microbiol (2001) 4.19

Immunogenicity and impact on nasopharyngeal carriage of a nonavalent pneumococcal conjugate vaccine. J Infect Dis (1999) 3.72

Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC. Curr Biol (1998) 3.51

Failure of chloramphenicol therapy in penicillin-resistant pneumococcal meningitis. Lancet (1992) 3.42

Expression profiling in the muscular dystrophies: identification of novel aspects of molecular pathophysiology. J Cell Biol (2000) 3.34

Prevalence of child physical and sexual abuse in the community. Results from the Ontario Health Supplement. JAMA (1997) 3.24

The L1 major capsid protein of human papillomavirus type 11 recombinant virus-like particles interacts with heparin and cell-surface glycosaminoglycans on human keratinocytes. J Biol Chem (1999) 3.16

Management of community-acquired pneumonia in the era of pneumococcal resistance: a report from the Drug-Resistant Streptococcus pneumoniae Therapeutic Working Group. Arch Intern Med (2000) 3.09

Loss-of-function mutations in the cathepsin C gene result in periodontal disease and palmoplantar keratosis. Nat Genet (1999) 3.01

Extracapsular cataract extraction compared with small incision surgery by phacoemulsification: a randomised trial. Br J Ophthalmol (2001) 2.98

Analgesic efficacy of ultrasound-guided transversus abdominis plane block in patients undergoing open appendicectomy. Br J Anaesth (2009) 2.83

CD21 is a ligand for CD23 and regulates IgE production. Nature (1992) 2.58

Severity of prevalent vertebral fractures and the risk of subsequent vertebral and nonvertebral fractures: results from the MORE trial. Bone (2003) 2.51

Genetic diversity of penicillin-binding protein 2B and 2X genes from Streptococcus pneumoniae in South Africa. Antimicrob Agents Chemother (1993) 2.44

The 5'-proximal region of the wheat Cab-1 gene contains a 268-bp enhancer-like sequence for phytochrome response. EMBO J (1987) 2.31

One-year prevalence of psychiatric disorder in Ontarians 15 to 64 years of age. Can J Psychiatry (1996) 2.18

Genetic diversity and molecular epidemiology of respiratory syncytial virus over four consecutive seasons in South Africa: identification of new subgroup A and B genotypes. J Gen Virol (2001) 2.09

Ketone bodies do not directly alter excitatory or inhibitory hippocampal synaptic transmission. Neurology (2000) 2.09

Increased disease burden and antibiotic resistance of bacteria causing severe community-acquired lower respiratory tract infections in human immunodeficiency virus type 1-infected children. Clin Infect Dis (2000) 2.02

Countercurrent immunoelectrophoresis of urine as well as of CSF and blood for diagnosis of bacterial meningitis. J Pediatr (1976) 2.00

Alterations in PBP 1A essential-for high-level penicillin resistance in Streptococcus pneumoniae. Antimicrob Agents Chemother (1998) 1.98

Hormonal control of the renal conversion of 25-hydroxycholecalciferol to 1,25-dihydroxycholecalciferol. J Clin Invest (1972) 1.93

Size and motion of the mitral valve annulus in man. I. A two-dimensional echocardiographic method and findings in normal subjects. Circulation (1981) 1.88

Lack of utility of serotyping multiple colonies for detection of simultaneous nasopharyngeal carriage of different pneumococcal serotypes. Pediatr Infect Dis J (2000) 1.87

Association of serotypes of Streptococcus pneumoniae with disease severity and outcome in adults: an international study. Clin Infect Dis (2007) 1.87

Recombinant 25-kDa CD23 and interleukin 1 alpha promote the survival of germinal center B cells: evidence for bifurcation in the development of centrocytes rescued from apoptosis. Eur J Immunol (1991) 1.82

Alterations in penicillin-binding protein 2B from penicillin-resistant wild-type strains of Streptococcus pneumoniae. Antimicrob Agents Chemother (1995) 1.82

Phytochrome activation of two nuclear genes requires cytoplasmic protein synthesis. EMBO J (1989) 1.81

The clinical value of serum CEA, CA19-9, and CA242 in the diagnosis and prognosis of pancreatic cancer. Eur J Surg Oncol (2005) 1.77

Laparoscopic complications in markedly obese urologic patients (a multi-institutional review) Urology (1996) 1.75

Spread of the Spanish multi-resistant serotype 23F clone of Streptococcus pneumoniae to Seoul, Korea. Microb Drug Resist (1997) 1.74

Nav1.7-related small fiber neuropathy: impaired slow-inactivation and DRG neuron hyperexcitability. Neurology (2012) 1.73

Neutrophil-epithelial crosstalk at the intestinal lumenal surface mediated by reciprocal secretion of adenosine and IL-6. J Clin Invest (2001) 1.73

Interrogating fiber Bragg grating sensors by thermally scanning a demultiplexer based on arrayed waveguide gratings. Opt Lett (2004) 1.71

Pneumococcal vaccines: an update on current strategies. Vaccine (2004) 1.69

Impact of human immunodeficiency virus type 1 on the disease spectrum of Streptococcus pneumoniae in South African children. Pediatr Infect Dis J (2000) 1.69

Evaluation of the Etest as a means of determining the antibiotic susceptibilities of isolates of Streptococcus pneumoniae and Haemophilus influenzae from children in the Central African Republic. J Antimicrob Chemother (2000) 1.67

Mutations in the dihydrofolate reductase gene of trimethoprim-resistant isolates of Streptococcus pneumoniae. Antimicrob Agents Chemother (1997) 1.66

Helicobacter pylori and oesophageal and gastric cancers in a prospective study in China. Br J Cancer (2006) 1.64

Age-related decline in female fertility is not due to diminished capacity of the uterus to sustain embryo implantation. Fertil Steril (1994) 1.64

Evidence that MIG-6 is a tumor-suppressor gene. Oncogene (2006) 1.62

Serotype 19f multiresistant pneumococcal clone harboring two erythromycin resistance determinants (erm(B) and mef(A)) in South Africa. Antimicrob Agents Chemother (2001) 1.60

Prospective study of serum 25(OH)-vitamin D concentration and risk of oesophageal and gastric cancers. Br J Cancer (2007) 1.60

Epidural analgesia compared with combined spinal-epidural analgesia during labor in nulliparous women. N Engl J Med (1997) 1.60

Neutralizing monoclonal antibodies to hepatocyte growth factor/scatter factor (HGF/SF) display antitumor activity in animal models. Proc Natl Acad Sci U S A (2001) 1.58

Antiretroviral therapy improves cognitive impairment in HIV+ individuals in sub-Saharan Africa. Neurology (2006) 1.56

Stimulation of aggrecan synthesis in cartilage explants by cyclic loading is localized to regions of high interstitial fluid flow. Arch Biochem Biophys (1999) 1.56

Clinical and nasopharyngeal isolates of unusual multiply resistant pneumococci. Am J Dis Child (1986) 1.55

Altered control of postural sway following cerebral infarction: a cross-sectional analysis. Neurology (2010) 1.55

Community-onset Staphylococcus aureus bacteraemia in hospitalised African children: high incidence in HIV-infected children and high prevalence of multidrug resistance. Paediatr Int Child Health (2012) 1.54

Increased burden of respiratory viral associated severe lower respiratory tract infections in children infected with human immunodeficiency virus type-1. J Pediatr (2000) 1.54

Laboratory-based diagnosis of pneumococcal pneumonia: state of the art and unmet needs. Clin Microbiol Infect (2011) 1.54

Hybrid papillomavirus L1 molecules assemble into virus-like particles that reconstitute conformational epitopes and induce neutralizing antibodies to distinct HPV types. Virology (2001) 1.52

Efficacy of Vi polysaccharide vaccine against strains of Salmonella typhi: reply. Vaccine (1998) 1.51

Abnormal homicide in Hong Kong. Br J Psychiatry (1973) 1.50

TDP-43 subtypes are associated with distinct atrophy patterns in frontotemporal dementia. Neurology (2010) 1.49

Antibiotic-resistant pneumococcal disease in South African children. Am J Dis Child (1992) 1.49

'Atypical' bacteria are a common cause of community-acquired pneumonia in hospitalised adults. S Afr Med J (1994) 1.46

Three predominant clones identified within penicillin-resistant South African isolates of Streptococcus pneumoniae. Microb Drug Resist (1997) 1.45

Sequence determination of human papillomavirus type 6a and assembly of virus-like particles in Saccharomyces cerevisiae. Virology (1995) 1.43

Prostaglandin E2 and nitric oxide mediate the acute inflammatory (erythemal) response to topical 5-aminolaevulinic acid photodynamic therapy in human skin. Br J Dermatol (2013) 1.42

Acquisition, carriage, and transmission of pneumococci with decreased antibiotic susceptibility in young children attending a day care facility in southern Israel. J Infect Dis (1998) 1.42

In vitro activities of 14 antibiotics against 100 human isolates of Yersinia pestis from a southern African plague focus. Antimicrob Agents Chemother (1996) 1.42

Impact of conjugate Haemophilus influenzae type b (Hib) vaccine introduction in South Africa. Bull World Health Organ (2006) 1.41

Alterations in MurM, a cell wall muropeptide branching enzyme, increase high-level penicillin and cephalosporin resistance in Streptococcus pneumoniae. Antimicrob Agents Chemother (2001) 1.40

Ring chromosome 14: a distinct clinical entity. J Med Genet (1981) 1.39

Adalimumab-induced asthma. Rheumatology (Oxford) (2005) 1.38

Long-term results of electrophysiologically guided sotalol therapy for life-threatening ventricular arrhythmias. Am Heart J (1996) 1.38

Rifampicin antibiotic impregnation of the St. Jude Medical mechanical valve sewing ring: a weapon against endocarditis. J Thorac Cardiovasc Surg (1996) 1.38

Clinical and cost effectiveness of surgery for morbid obesity: a systematic review and economic evaluation. Int J Obes Relat Metab Disord (2003) 1.38

Gradual phenotypic conversion associated with immortalization of cultured human mammary epithelial cells. Mol Biol Cell (1997) 1.37

Overexpression of HAb18G/CD147 promotes invasion and metastasis via alpha3beta1 integrin mediated FAK-paxillin and FAK-PI3K-Ca2+ pathways. Cell Mol Life Sci (2008) 1.37

The impact of HIV on Streptococcus pneumoniae bacteraemia in a South African population. AIDS (1998) 1.35

Rapid identification of Candida dubliniensis using a species-specific molecular beacon. J Clin Microbiol (2000) 1.34

Increased carriage of trimethoprim/sulfamethoxazole-resistant Streptococcus pneumoniae in Malawian children after treatment for malaria with sulfadoxine/pyrimethamine. J Infect Dis (2000) 1.33

Cardioprotective effects of 70-kDa heat shock protein in transgenic mice. Proc Natl Acad Sci U S A (1996) 1.32

Mutations in ribosomal protein L16 conferring reduced susceptibility to evernimicin (SCH27899): implications for mechanism of action. Antimicrob Agents Chemother (2000) 1.32

5' phospholipid phosphatase SHIP-2 causes protein kinase B inactivation and cell cycle arrest in glioblastoma cells. Mol Cell Biol (2000) 1.31

Neutralization of human papillomavirus (HPV) pseudovirions: a novel and efficient approach to detect and characterize HPV neutralizing antibodies. Virology (2000) 1.31

Intranasal treatment of cowpox virus respiratory infections in mice with cidofovir. Antiviral Res (2000) 1.30

Long-term survival of Streptococcus pneumoniae at room temperature on Dorset egg medium. J Clin Microbiol (1998) 1.26

Regenerated mdx mouse skeletal muscle shows differential mRNA expression. J Appl Physiol (1985) (2002) 1.26

Rapid detection of penicillin-resistant Streptococcus pneumoniae in cerebrospinal fluid by a seminested-PCR strategy. J Clin Microbiol (1998) 1.26

Neural correlates of working memory in Temporal Lobe Epilepsy--an fMRI study. Neuroimage (2012) 1.25

Non-Penicillin-Binding protein mediated high-level penicillin and cephalosporin resistance in a Hungarian clone of Streptococcus pneumoniae. Microb Drug Resist (2000) 1.24

Third chronological supplement to the carcinogenic potency database: standardized results of animal bioassays published through December 1986 and by the National Toxicology Program through June 1987. Environ Health Perspect (1990) 1.24

Molecular basis of rifampin resistance in Streptococcus pneumoniae. Antimicrob Agents Chemother (1999) 1.24

Streptococcus pneumoniae blood culture isolates from patients with and without human immunodeficiency virus infection: alterations in penicillin susceptibilities and in serogroups or serotypes. Clin Infect Dis (1997) 1.23

Upper gastrointestinal endoscopy performed by nurses: scope for the future? Gut (2003) 1.23

Viral oncogenes accelerate conversion to immortality of cultured conditionally immortal human mammary epithelial cells. Oncogene (1999) 1.22

Is familial non-medullary thyroid carcinoma more aggressive than sporadic thyroid cancer? A multicenter series. Surgery (2000) 1.22