Modulation of the two promoters of the galactose operon of Escherichia coli.

PubWeight™: 2.91‹?› | Rank: Top 1%

🔗 View Article (PMID 221830)

Published in Nature on June 07, 1979

Authors

S Adhya, W Miller

Articles citing this

Linkage map of Escherichia coli K-12, edition 6. Microbiol Rev (1980) 27.40

lon transcriptional regulation of genes necessary for capsular polysaccharide synthesis in Escherichia coli K-12. J Bacteriol (1984) 3.26

Sequence of galR gene indicates a common evolutionary origin of lac and gal repressor in Escherichia coli. Proc Natl Acad Sci U S A (1982) 2.77

Cyclic nucleotides in procaryotes. Microbiol Rev (1981) 2.67

Demonstration of two operator elements in gal: in vitro repressor binding studies. Proc Natl Acad Sci U S A (1984) 2.54

The structure of tandem regulatory regions in the deo operon of Escherichia coli K12. EMBO J (1982) 2.28

The interaction of the recognition helix of lac repressor with lac operator. EMBO J (1987) 2.19

lac Repressor blocks transcribing RNA polymerase and terminates transcription. Proc Natl Acad Sci U S A (1986) 2.07

Carbon starvation and growth rate-dependent regulation of the Escherichia coli ribosomal RNA promoters: differential control of dual promoters. Proc Natl Acad Sci U S A (1983) 1.98

Repressor induced site-specific binding of HU for transcriptional regulation. EMBO J (1997) 1.94

Mutational analysis of the redox-sensitive transcriptional regulator OxyR: regions important for DNA binding and multimerization. J Bacteriol (1995) 1.89

Tandem CRP binding sites in the deo operon of Escherichia coli K-12. EMBO J (1982) 1.83

DNA sequence of the carA gene and the control region of carAB: tandem promoters, respectively controlled by arginine and the pyrimidines, regulate the synthesis of carbamoyl-phosphate synthetase in Escherichia coli K-12. Proc Natl Acad Sci U S A (1984) 1.81

Synthetic lac operator mediates repression through lac repressor when introduced upstream and downstream from lac promoter. EMBO J (1986) 1.80

Characterization of two mutations in the Escherichia coli galE gene inactivating the second galactose operator and comparative studies of repressor binding. EMBO J (1983) 1.72

Unusual organization of the ilvIH promoter of Escherichia coli. J Bacteriol (1985) 1.68

Interaction of spatially separated protein-DNA complexes for control of gene expression: operator conversions. Proc Natl Acad Sci U S A (1988) 1.58

Footprinting analysis of mammalian RNA polymerase II along its transcript: an alternative view of transcription elongation. Proc Natl Acad Sci U S A (1991) 1.52

RNA polymerase idling and clearance in gal promoters: use of supercoiled minicircle DNA template made in vivo. Proc Natl Acad Sci U S A (1993) 1.40

Cyclic AMP-induced conformational change of cyclic AMP receptor protein (CRP): intragenic suppressors of cyclic AMP-independent CRP mutations. J Bacteriol (1988) 1.37

L factor that is required for beta-galactosidase synthesis is the nusA gene product involved in transcription termination. Proc Natl Acad Sci U S A (1980) 1.32

Cyclic AMP-dependent constitutive expression of gal operon: use of repressor titration to isolate operator mutations. Proc Natl Acad Sci U S A (1983) 1.30

NADP, corepressor for the Bacillus catabolite control protein CcpA. Proc Natl Acad Sci U S A (1998) 1.28

The upstream operator of the Escherichia coli galactose operon is sufficient for repression of transcription initiated at the cyclic AMP-stimulated promoter. EMBO J (1986) 1.27

Control of transcription of gal repressor and isorepressor genes in Escherichia coli. J Bacteriol (1993) 1.26

A "master" in base unpairing during isomerization of a promoter upon RNA polymerase binding. Proc Natl Acad Sci U S A (2001) 1.25

Regulatory architecture of the iron-regulated fepD-ybdA bidirectional promoter region in Escherichia coli. J Bacteriol (2001) 1.24

Effect of Escherichia coli nusG function on lambda N-mediated transcription antitermination. J Bacteriol (1992) 1.23

lac repressor mutants with double or triple exchanges in the recognition helix bind specifically to lac operator variants with multiple exchanges. EMBO J (1989) 1.18

Genetics of galactose metabolism of Erwinia amylovora and its influence on polysaccharide synthesis and virulence of the fire blight pathogen. J Bacteriol (1994) 1.16

Unusual properties of promoter-up mutations in the Escherichia coli galactose operon and evidence suggesting RNA polymerase-induced DNA bending. EMBO J (1987) 1.15

Further inducibility of a constitutive system: ultrainduction of the gal operon. J Bacteriol (1991) 1.12

In vivo regulation of the uvrA gene: role of the "-10" and "-35" promoter regions. Nucleic Acids Res (1983) 1.10

Cyclic-AMP-dependent switch in initiation of transcription from the two promoters of the Escherichia coli gal operon: identification and assay of 5'-triphosphate ends of mRNA by GTP:RNA guanyltransferase. J Bacteriol (1989) 1.09

Cellular stress created by intermediary metabolite imbalances. Proc Natl Acad Sci U S A (2009) 1.09

Divergent effects of cyclic adenosine 3',5'-monophosphate on formation of type 1 fimbriae in different K-12 strains of Escherichia coli. J Bacteriol (1981) 1.08

Regulation of galactose operon expression: glucose effects and role of cyclic adenosine 3',5'-monophosphate. J Bacteriol (1981) 0.97

Interaction of Gal repressor with inducer and operator: induction of gal transcription from repressor-bound DNA. Proc Natl Acad Sci U S A (1997) 0.93

Identification of a complex operator for galP1, the glucose-sensitive, galactose-dependent promoter of the Streptomyces galactose operon. J Bacteriol (1993) 0.91

Genetic interaction between the beta' subunit of RNA polymerase and the arginine-rich domain of Escherichia coli nusA protein. J Bacteriol (1991) 0.89

nusA amber mutation that causes temperature-sensitive growth of Escherichia coli. J Bacteriol (1988) 0.88

Guanylate cyclase activity in Escherichia coli mutants defective in adenylate cyclase. J Bacteriol (1981) 0.88

DNA conformational change in Gal repressor-operator complex: involvement of central G-C base pair(s) of dyad symmetry. Nucleic Acids Res (1988) 0.88

A rapid assay for affinity and kinetics of molecular interactions with nucleic acids. Nucleic Acids Res (2011) 0.88

DNA sequences in gal operon override transcription elongation blocks. J Mol Biol (2008) 0.88

Independence of cyclic AMP and relA gene stimulation of glycogen synthesis in intact Escherichia coli cells. J Bacteriol (1985) 0.88

Analysis of transcription termination signals in the nin region of bacteriophage lambda: the roc deletion. J Bacteriol (1988) 0.87

Transcription termination signals in the nin region of bacteriophage lambda: identification of Rho-dependent termination regions. Genetics (1995) 0.87

A single-base-pair mutation changes the specificities of both a transcription activation protein and its binding site. Proc Natl Acad Sci U S A (1993) 0.84

Methylation-dependent transcription controls plasmid replication of the CloDF13 cop-1(Ts) mutant. J Bacteriol (1986) 0.83

Induction of the galactose enzymes in Escherichia coli is independent of the C-1-hydroxyl optical configuration of the inducer D-galactose. J Bacteriol (2008) 0.80

Phage HK022 Nun protein represses translation of phage lambda N (transcription termination/translation repression). Proc Natl Acad Sci U S A (2003) 0.80

In vivo transcription dynamics of the galactose operon: a study on the promoter transition from P1 to P2 at onset of stationary phase. PLoS One (2011) 0.77

Differential role of base pairs on gal promoters strength. J Mol Biol (2014) 0.76

Molecular Mechanisms of Transcription Initiation at gal Promoters and their Multi-Level Regulation by GalR, CRP and DNA Loop. Biomolecules (2015) 0.75

Regulation of galactose-1-phosphate uridyltransferase gene expression. Eur J Pediatr (1995) 0.75

Fusion of the promoter region of rRNA operon rrnB to lac Z gene. Nucleic Acids Res (1980) 0.75

Genome-Wide Transcriptional Regulation and Chromosome Structural Arrangement by GalR in E. coli. Front Mol Biosci (2016) 0.75

Articles by these authors

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res (1997) 665.31

Basic local alignment search tool. J Mol Biol (1990) 659.07

A greedy algorithm for aligning DNA sequences. J Comput Biol (2000) 47.89

Optimal alignments in linear space. Comput Appl Biosci (1988) 38.10

Protein sequence similarity searches using patterns as seeds. Nucleic Acids Res (1998) 23.87

The UCSC Genome Browser Database: 2008 update. Nucleic Acids Res (2007) 23.13

A computer program for aligning a cDNA sequence with a genomic DNA sequence. Genome Res (1998) 22.69

Aligning two sequences within a specified diagonal band. Comput Appl Biosci (1992) 19.31

PipMaker--a web server for aligning two genomic DNA sequences. Genome Res (2000) 17.46

Evidence for two functional gal promoters in intact Escherichia coli cells. J Biol Chem (1981) 17.42

Complete genome sequence of Salmonella enterica serovar Typhimurium LT2. Nature (2001) 16.89

Comparative analyses of multi-species sequences from targeted genomic regions. Nature (2003) 13.31

Identification of a coordinate regulator of interleukins 4, 13, and 5 by cross-species sequence comparisons. Science (2000) 10.14

Control of transcription termination. Annu Rev Biochem (1978) 9.24

Long human-mouse sequence alignments reveal novel regulatory elements: a reason to sequence the mouse genome. Genome Res (1997) 8.49

Scoring pairwise genomic sequence alignments. Pac Symp Biocomput (2002) 8.42

Comparison of DNA sequences with protein sequences. Genomics (1997) 7.76

Cyclic adenosine 5'-monophosphate in Escherichia coli. Bacteriol Rev (1976) 7.55

Transcriptional regulation by cAMP and its receptor protein. Annu Rev Biochem (1993) 6.49

Mapping sequenced E.coli genes by computer: software, strategies and examples. Nucleic Acids Res (1991) 6.29

Dual control for transcription of the galactose operon by cyclic AMP and its receptor protein at two interspersed promoters. Cell (1977) 5.29

Isolation and characterization of conditional lethal mutants of Escherichia coli defective in transcription termination factor rho. Proc Natl Acad Sci U S A (1976) 4.93

Large-scale comparative sequence analysis of the human and murine Bruton's tyrosine kinase loci reveals conserved regulatory domains. Genome Res (1997) 4.82

Promoter occlusion: transcription through a promoter may inhibit its activity. Cell (1982) 4.43

Bending of DNA by gene-regulatory proteins: construction and use of a DNA bending vector. Gene (1989) 4.41

A family of bacterial regulators homologous to Gal and Lac repressors. J Biol Chem (1992) 4.07

Alignment of Escherichia coli K12 DNA sequences to a genomic restriction map. Nucleic Acids Res (1990) 4.07

A controlled trial of a formalin-inactivated hepatitis A vaccine in healthy children. N Engl J Med (1992) 4.05

Comparative sequence analysis of a gene-rich cluster at human chromosome 12p13 and its syntenic region in mouse chromosome 6. Genome Res (1998) 3.80

Locus control regions of mammalian beta-globin gene clusters: combining phylogenetic analyses and experimental results to gain functional insights. Gene (1997) 3.77

A control element within a structural gene: the gal operon of Escherichia coli. Cell (1983) 3.62

The natural history of recurrent herpes simplex labialis: implications for antiviral therapy. N Engl J Med (1977) 3.61

A local alignment tool for very long DNA sequences. Comput Appl Biosci (1995) 3.58

Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): I. As2O3 exerts dose-dependent dual effects on APL cells. Blood (1997) 3.56

A deletion analysis of prophage lambda and adjacent genetic regions. Proc Natl Acad Sci U S A (1968) 3.46

Long-circulating bacteriophage as antibacterial agents. Proc Natl Acad Sci U S A (1996) 3.34

Post-processing long pairwise alignments. Bioinformatics (1999) 3.00

A space-efficient algorithm for local similarities. Comput Appl Biosci (1990) 2.98

Glucose effect and the galactose enzymes of Escherichia coli: correlation between glucose inhibition of induction and inducer transport. J Bacteriol (1966) 2.97

Transcription antitermination by bacteriophage lambda N gene product. J Mol Biol (1980) 2.95

Functional domains of Pseudomonas exotoxin identified by deletion analysis of the gene expressed in E. coli. Cell (1987) 2.93

Release of polarity in Escherichia coli by gene N of phage lambda: termination and antitermination of transcription. Proc Natl Acad Sci U S A (1974) 2.92

Comparative analysis of the gene-dense ACHE/TFR2 region on human chromosome 7q22 with the orthologous region on mouse chromosome 5. Nucleic Acids Res (2001) 2.89

A comparison of filtered leukocyte-reduced and cytomegalovirus (CMV) seronegative blood products for the prevention of transfusion-associated CMV infection after marrow transplant. Blood (1995) 2.83

Polycystic ovaries treated by laparoscopic laser vaporization. Fertil Steril (1989) 2.77

Effect of Rho on transcription of bacterial operons. Nat New Biol (1973) 2.74

Analysis of the quality and utility of random shotgun sequencing at low redundancies. Genome Res (1998) 2.74

Correlation of the highest-energy cosmic rays with nearby extragalactic objects. Science (2007) 2.57

Demonstration of two operator elements in gal: in vitro repressor binding studies. Proc Natl Acad Sci U S A (1984) 2.54

Metabolism of (14C) cefaclor, a cephalosporin antibiotic, in three species of laboratory animals. Antimicrob Agents Chemother (1976) 2.52

Comparative genome analysis delimits a chromosomal domain and identifies key regulatory elements in the alpha globin cluster. Hum Mol Genet (2001) 2.46

Treatment of moderate/severe acute graft-versus-host disease after allogeneic bone marrow transplantation: an analysis of clinical risk features and outcome. Blood (1990) 2.38

Globin gene server: a prototype E-mail database server featuring extensive multiple alignments and data compilation for electronic genetic analysis. Genomics (1994) 2.36

Sites of allosteric shift in the structure of the cyclic AMP receptor protein. Cell (1985) 2.36

Site-specific DNA binding of nuclear factor I: analyses of cellular binding sites. Mol Cell Biol (1985) 2.19

Comparison of five methods for finding conserved sequences in multiple alignments of gene regulatory regions. Nucleic Acids Res (1999) 2.19

Biotin-requiring mutants of Escherichia coli K-12. J Bacteriol (1967) 2.16

Phosphoglucomutase mutants of Escherichia coli K-12. J Bacteriol (1971) 2.07

Comparison of the Escherichia coli K-12 genome with sampled genomes of a Klebsiella pneumoniae and three salmonella enterica serovars, Typhimurium, Typhi and Paratyphi. Nucleic Acids Res (2000) 2.07

Recommendations from an international expert panel on the use of neoadjuvant (primary) systemic treatment of operable breast cancer: new perspectives 2006. Ann Oncol (2007) 2.05

Characterization of the human and mouse unconventional myosin XV genes responsible for hereditary deafness DFNB3 and shaker 2. Genomics (1999) 1.97

A tool for aligning very similar DNA sequences. Comput Appl Biosci (1997) 1.97

Alignments without low-scoring regions. J Comput Biol (1998) 1.96

Activation of transcription at specific promoters by glycerol. J Biol Chem (1974) 1.95

Comparative sequence of human and mouse BAC clones from the mnd2 region of chromosome 2p13. Genome Res (1999) 1.94

Repressor induced site-specific binding of HU for transcriptional regulation. EMBO J (1997) 1.94

Cooperative DNA binding of heterologous proteins: evidence for contact between the cyclic AMP receptor protein and RNA polymerase. Proc Natl Acad Sci U S A (1988) 1.94

Diabetes mellitus: an underestimated public health program. J Chronic Dis (1975) 1.87

Sequence and comparative analysis of the mouse 1-megabase region orthologous to the human 11p15 imprinted domain. Genome Res (2000) 1.85

How cyclic AMP and its receptor protein act in Escherichia coli. Cell (1982) 1.77

Chaining multiple-alignment blocks. J Comput Biol (1994) 1.75

Analysis of genetic instability during mammary tumor progression using a novel selection-based assay for in vivo mutations in a bacteriophage lambda transgene target. Proc Natl Acad Sci U S A (1996) 1.73

Activity of immunotoxins constructed with modified Pseudomonas exotoxin A lacking the cell recognition domain. J Biol Chem (1988) 1.73

The galactose regulon of Escherichia coli. Mol Microbiol (1993) 1.72

Genome sequence comparisons: hurdles in the fast lane to functional genomics. Brief Bioinform (2000) 1.71

DNA looping in cellular repression of transcription of the galactose operon. Genes Dev (1990) 1.70

Accuracy of bedside chest hard-copy screen-film versus hard- and soft-copy computed radiographs in a medical intensive care unit: receiver operating characteristic analysis. Radiology (1997) 1.69

Software tools for analyzing pairwise alignments of long sequences. Nucleic Acids Res (1991) 1.68

Approximate matching of regular expressions. Bull Math Biol (1989) 1.68

Positive and negative regulatory elements of the rabbit embryonic epsilon-globin gene revealed by an improved multiple alignment program and functional analysis. DNA Seq (1993) 1.66

Rapid and sensitive detection of Leishmania kinetoplast DNA from spleen and blood samples of kala-azar patients. Parasitology (1992) 1.65

Control of gal transcription through DNA looping: inhibition of the initial transcribing complex. Proc Natl Acad Sci U S A (1992) 1.65

Dynamic programming algorithms for biological sequence comparison. Methods Enzymol (1992) 1.65

The Paced Auditory Serial Addition Task (PASAT): norms for age, education, and ethnicity. Assessment (1998) 1.65

Histone-like protein HU as a specific transcriptional regulator: co-factor role in repression of gal transcription by GAL repressor. Genes Cells (1996) 1.65

DNA bending by negative regulatory proteins: Gal and Lac repressors. Genes Dev (1989) 1.62

Racism, society, and disease: an exploration of the social and biological mechanisms of differential mortality. Int J Health Serv (1981) 1.62

Repression and activation of transcription by Gal and Lac repressors: involvement of alpha subunit of RNA polymerase. EMBO J (1995) 1.60

Conserved E boxes function as part of the enhancer in hypersensitive site 2 of the beta-globin locus control region. Role of basic helix-loop-helix proteins. J Biol Chem (1997) 1.58

Interaction of spatially separated protein-DNA complexes for control of gene expression: operator conversions. Proc Natl Acad Sci U S A (1988) 1.58

Improved mortality among U.S. Blacks, 1968-1978: the role of antiracist struggle. Int J Health Serv (1981) 1.53

Bacteriophage K1-5 encodes two different tail fiber proteins, allowing it to infect and replicate on both K1 and K5 strains of Escherichia coli. J Virol (2001) 1.50

Recent developments in linear-space alignment methods: a survey. J Comput Biol (1994) 1.49

Activity of a recombinant fusion protein between transforming growth factor type alpha and Pseudomonas toxin. Proc Natl Acad Sci U S A (1987) 1.48

Measurement of the depth of maximum of extensive air showers above 10{18} eV. Phys Rev Lett (2010) 1.48

Gal repressosome contains an antiparallel DNA loop. Nat Struct Biol (2001) 1.48

In vitro repression of the transcription of gas operon by purified gal repressor. Proc Natl Acad Sci U S A (1973) 1.48

A randomized trial comparing prednisone with antithymocyte globulin/prednisone as an initial systemic therapy for moderately severe acute graft-versus-host disease. Biol Blood Marrow Transplant (2000) 1.48

Allosteric changes in the cAMP receptor protein of Escherichia coli: hinge reorientation. Proc Natl Acad Sci U S A (1992) 1.45