Published in Proc Natl Acad Sci U S A on December 20, 2011
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NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc Natl Acad Sci U S A (2006) 21.58
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The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation. Science (2002) 13.86
Chimeric nucleases stimulate gene targeting in human cells. Science (2003) 12.12
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Antibody-based protection against HIV infection by vectored immunoprophylaxis. Nature (2011) 3.80
miR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice. J Exp Med (2011) 3.78
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NF-kappaB dysregulation in microRNA-146a-deficient mice drives the development of myeloid malignancies. Proc Natl Acad Sci U S A (2011) 2.74
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Encoding NF-kappaB temporal control in response to TNF: distinct roles for the negative regulators IkappaBalpha and A20. Genes Dev (2008) 2.29
Essential role for STAT5 signaling in CD25+CD4+ regulatory T cell homeostasis and the maintenance of self-tolerance. J Immunol (2003) 2.13
Regulation of NF-kappaB activity through lysine monomethylation of p65. Proc Natl Acad Sci U S A (2009) 2.10
Engineered lentivector targeting of dendritic cells for in vivo immunization. Nat Biotechnol (2008) 2.05
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Sam68 is required for both NF-κB activation and apoptosis signaling by the TNF receptor. Mol Cell (2011) 1.73
Targeting lentiviral vectors to specific cell types in vivo. Proc Natl Acad Sci U S A (2006) 1.71
Broad protection against influenza infection by vectored immunoprophylaxis in mice. Nat Biotechnol (2013) 1.71
MicroRNA-34a perturbs B lymphocyte development by repressing the forkhead box transcription factor Foxp1. Immunity (2010) 1.70
MicroRNA-146 represses endothelial activation by inhibiting pro-inflammatory pathways. EMBO Mol Med (2013) 1.70
Multifunctional T-cell analyses to study response and progression in adoptive cell transfer immunotherapy. Cancer Discov (2013) 1.68
IkappaBbeta acts to inhibit and activate gene expression during the inflammatory response. Nature (2010) 1.68
Essential roles of the kappa light chain intronic enhancer and 3' enhancer in kappa rearrangement and demethylation. Nat Immunol (2002) 1.63
Antitumor activity from antigen-specific CD8 T cells generated in vivo from genetically engineered human hematopoietic stem cells. Proc Natl Acad Sci U S A (2011) 1.61
MicroRNAs, new effectors and regulators of NF-κB. Immunol Rev (2012) 1.61
The combined absence of NF-kappa B1 and c-Rel reveals that overlapping roles for these transcription factors in the B cell lineage are restricted to the activation and function of mature cells. Proc Natl Acad Sci U S A (2002) 1.59
MicroRNA-125b potentiates macrophage activation. J Immunol (2011) 1.47
Epistasis between microRNAs 155 and 146a during T cell-mediated antitumor immunity. Cell Rep (2012) 1.46
Unique CD40-mediated biological program in B cell activation requires both type 1 and type 2 NF-kappaB activation pathways. Proc Natl Acad Sci U S A (2004) 1.39
MicroRNA-146a acts as a guardian of the quality and longevity of hematopoietic stem cells in mice. Elife (2013) 1.36
Reconstruction of the 1918 influenza virus: unexpected rewards from the past. MBio (2012) 1.34
Requirement for the NF-kappaB family member RelA in the development of secondary lymphoid organs. J Exp Med (2002) 1.32
Pregnancy induces a fetal antigen-specific maternal T regulatory cell response that contributes to tolerance. Proc Natl Acad Sci U S A (2010) 1.26
Generation of functional antigen-specific T cells in defined genetic backgrounds by retrovirus-mediated expression of TCR cDNAs in hematopoietic precursor cells. Proc Natl Acad Sci U S A (2002) 1.22
Oncomir miR-125b regulates hematopoiesis by targeting the gene Lin28A. Proc Natl Acad Sci U S A (2012) 1.22
Regulation of monocyte functional heterogeneity by miR-146a and Relb. Cell Rep (2012) 1.19
A computational-experimental approach identifies mutations that enhance surface expression of an oseltamivir-resistant influenza neuraminidase. PLoS One (2011) 1.16
Engineering human hematopoietic stem/progenitor cells to produce a broadly neutralizing anti-HIV antibody after in vitro maturation to human B lymphocytes. Blood (2008) 1.14
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Lentiviral vector delivery of human interleukin-7 (hIL-7) to human immune system (HIS) mice expands T lymphocyte populations. PLoS One (2010) 1.13
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Inhibitory effect of HIV-specific neutralizing IgA on mucosal transmission of HIV in humanized mice. Blood (2012) 1.11
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RNA splicing regulates the temporal order of TNF-induced gene expression. Proc Natl Acad Sci U S A (2013) 1.01
Adoptive transfer of MART-1 T-cell receptor transgenic lymphocytes and dendritic cell vaccination in patients with metastatic melanoma. Clin Cancer Res (2014) 1.01
Allelic exclusion and peripheral reconstitution by TCR transgenic T cells arising from transduced human hematopoietic stem/progenitor cells. Mol Ther (2013) 1.00
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Dimeric 2G12 as a potent protection against HIV-1. PLoS Pathog (2010) 0.98
The Yin and Yang of microRNAs: leukemia and immunity. Immunol Rev (2013) 0.98
Inhibition of DNA binding by NF-kappa B with pyrrole-imidazole polyamides. Biochemistry (2002) 0.97
Activation of the transcriptional function of the NF-κB protein c-Rel by O-GlcNAc glycosylation. Sci Signal (2013) 0.97
Targeting lentiviral vectors to antigen-specific immunoglobulins. Hum Gene Ther (2008) 0.96
As good as it gets? The problem of HIV persistence despite antiretroviral drugs. Cell Host Microbe (2012) 0.94
Uncovering the V(D)J recombinase. Cell (2004) 0.93
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Homeostatic cytokines orchestrate the segregation of CD4 and CD8 memory T-cell reservoirs in mice. Blood (2011) 0.91
CD4+CD25- T cells transduced to express MHC class I-restricted epitope-specific TCR synthesize Th1 cytokines and exhibit MHC class I-restricted cytolytic effector function in a human melanoma model. J Immunol (2008) 0.90
Regulation of stress-induced hematopoiesis. Curr Opin Hematol (2015) 0.84
EHMT1 protein binds to nuclear factor-κB p50 and represses gene expression. J Biol Chem (2012) 0.82
A TLR4 agonist synergizes with dendritic cell-directed lentiviral vectors for inducing antigen-specific immune responses. Vaccine (2012) 0.79
Exploring the limits of ultrafast polymerase chain reaction using liquid for thermal heat exchange: A proof of principle. Appl Phys Lett (2010) 0.78
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Use of mutated self-cleaving 2A peptides as a molecular rheostat to direct simultaneous formation of membrane and secreted anti-HIV immunoglobulins. PLoS One (2012) 0.78
Overcoming barriers to programming a therapeutic cellular immune response to fight melanoma. Pigment Cell Melanoma Res (2010) 0.77
Regulation of APC development, immune response, and autoimmunity by Bach1/HO-1 pathway in mice. Blood (2012) 0.77
Retraction. Uncoupling IL-2 signals that regulate T cell proliferation, survival, and Fas-mediated activation-induced cell death. Immunity (2009) 0.77
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