PubRank

Richard K Wilson

Author PubWeight™ 1171.01‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Initial sequencing and comparative analysis of the mouse genome. Nature 2002 96.15
2 A second generation human haplotype map of over 3.1 million SNPs. Nature 2007 85.39
3 Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature 2007 75.09
4 Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes. Genome Res 2005 44.08
5 Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 2010 39.09
6 DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome. Nature 2008 38.13
7 Recurring mutations found by sequencing an acute myeloid leukemia genome. N Engl J Med 2009 33.09
8 Whole-genome sequencing and variant discovery in C. elegans. Nat Methods 2008 31.92
9 Mapping and sequencing of structural variation from eight human genomes. Nature 2008 30.28
10 Somatic mutations affect key pathways in lung adenocarcinoma. Nature 2008 30.02
11 International network of cancer genome projects. Nature 2010 20.35
12 Genome remodelling in a basal-like breast cancer metastasis and xenograft. Nature 2010 19.68
13 The B73 maize genome: complexity, diversity, and dynamics. Science 2009 18.73
14 BreakDancer: an algorithm for high-resolution mapping of genomic structural variation. Nat Methods 2009 18.41
15 Evolution of genes and genomes on the Drosophila phylogeny. Nature 2007 18.01
16 Genome-wide detection and characterization of positive selection in human populations. Nature 2007 17.27
17 Characterizing the cancer genome in lung adenocarcinoma. Nature 2007 16.48
18 Evolutionary and biomedical insights from the rhesus macaque genome. Science 2007 16.21
19 Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma. Cancer Cell 2010 16.12
20 VarScan: variant detection in massively parallel sequencing of individual and pooled samples. Bioinformatics 2009 16.04
21 VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing. Genome Res 2012 15.90
22 Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing. Nature 2012 14.33
23 DNMT3A mutations in acute myeloid leukemia. N Engl J Med 2010 14.07
24 The genome sequence of Caenorhabditis briggsae: a platform for comparative genomics. PLoS Biol 2003 13.32
25 The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes. Nature 2003 12.44
26 The genetic basis of early T-cell precursor acute lymphoblastic leukaemia. Nature 2012 9.89
27 De novo gene disruptions in children on the autistic spectrum. Neuron 2012 9.69
28 The origin and evolution of mutations in acute myeloid leukemia. Cell 2012 9.66
29 A high-resolution map of human evolutionary constraint using 29 mammals. Nature 2011 8.67
30 Comparison of genome degradation in Paratyphi A and Typhi, human-restricted serovars of Salmonella enterica that cause typhoid. Nat Genet 2004 8.60
31 A catalog of reference genomes from the human microbiome. Science 2010 8.10
32 Whole-genome analysis informs breast cancer response to aromatase inhibition. Nature 2012 8.03
33 Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas. Nat Genet 2012 7.61
34 Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome. Genome Res 2007 7.05
35 The DNA sequence of the human X chromosome. Nature 2005 6.97
36 Clonal architecture of secondary acute myeloid leukemia. N Engl J Med 2012 6.71
37 Genomic landscape of non-small cell lung cancer in smokers and never-smokers. Cell 2012 6.09
38 Viral discovery and sequence recovery using DNA microarrays. PLoS Biol 2003 5.95
39 The genome of a songbird. Nature 2010 5.90
40 Evolution of symbiotic bacteria in the distal human intestine. PLoS Biol 2007 5.79
41 Genome analysis of the platypus reveals unique signatures of evolution. Nature 2008 5.74
42 SomaticSniper: identification of somatic point mutations in whole genome sequencing data. Bioinformatics 2011 5.62
43 A genome-wide comparison of recent chimpanzee and human segmental duplications. Nature 2005 5.51
44 Characterization of missing human genome sequences and copy-number polymorphic insertions. Nat Methods 2010 5.44
45 Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia. N Engl J Med 2014 5.37
46 CREST maps somatic structural variation in cancer genomes with base-pair resolution. Nat Methods 2011 5.34
47 A genetic variation map for chicken with 2.8 million single-nucleotide polymorphisms. Nature 2004 5.24
48 Modernizing reference genome assemblies. PLoS Biol 2011 5.23
49 A novel retinoblastoma therapy from genomic and epigenetic analyses. Nature 2012 5.02
50 Novel mutations target distinct subgroups of medulloblastoma. Nature 2012 4.82
51 MuSiC: identifying mutational significance in cancer genomes. Genome Res 2012 4.73
52 The genome of the Western clawed frog Xenopus tropicalis. Science 2010 4.70
53 Landscape of somatic retrotransposition in human cancers. Science 2012 4.37
54 Abundant gene conversion between arms of palindromes in human and ape Y chromosomes. Nature 2003 4.31
55 Acquired copy number alterations in adult acute myeloid leukemia genomes. Proc Natl Acad Sci U S A 2009 4.17
56 Insights into hominid evolution from the gorilla genome sequence. Nature 2012 4.12
57 Use of whole-genome sequencing to diagnose a cryptic fusion oncogene. JAMA 2011 4.11
58 Characterizing a model human gut microbiota composed of members of its two dominant bacterial phyla. Proc Natl Acad Sci U S A 2009 4.09
59 Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes. Nat Genet 2011 4.02
60 The Pristionchus pacificus genome provides a unique perspective on nematode lifestyle and parasitism. Nat Genet 2008 3.93
61 Somatic mutations and germline sequence variants in the expressed tyrosine kinase genes of patients with de novo acute myeloid leukemia. Blood 2008 3.89
62 Endocrine-therapy-resistant ESR1 variants revealed by genomic characterization of breast-cancer-derived xenografts. Cell Rep 2013 3.85
63 Comparative and demographic analysis of orang-utan genomes. Nature 2011 3.83
64 Distinct patterns of mutations occurring in de novo AML versus AML arising in the setting of severe congenital neutropenia. Blood 2007 3.73
65 A burst of segmental duplications in the genome of the African great ape ancestor. Nature 2009 3.63
66 Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas. Nat Genet 2013 3.51
67 The genomic landscape of hypodiploid acute lymphoblastic leukemia. Nat Genet 2013 3.43
68 Evolutionary toggling of the MAPT 17q21.31 inversion region. Nat Genet 2008 3.42
69 The next-generation sequencing revolution and its impact on genomics. Cell 2013 3.35
70 A human genome structural variation sequencing resource reveals insights into mutational mechanisms. Cell 2010 3.22
71 The DNA sequence of human chromosome 7. Nature 2003 3.18
72 The theory of discovering rare variants via DNA sequencing. BMC Genomics 2009 3.12
73 Great ape genetic diversity and population history. Nature 2013 2.95
74 Chimpanzee and human Y chromosomes are remarkably divergent in structure and gene content. Nature 2010 2.92
75 Genomic and metabolic adaptations of Methanobrevibacter smithii to the human gut. Proc Natl Acad Sci U S A 2007 2.79
76 The structure and evolution of centromeric transition regions within the human genome. Nature 2004 2.78
77 Sequencing of the sea lamprey (Petromyzon marinus) genome provides insights into vertebrate evolution. Nat Genet 2013 2.76
78 Reconstructing complex regions of genomes using long-read sequencing technology. Genome Res 2014 2.63
79 Identification of a novel TP53 cancer susceptibility mutation through whole-genome sequencing of a patient with therapy-related AML. JAMA 2011 2.61
80 Aspects of coverage in medical DNA sequencing. BMC Bioinformatics 2008 2.60
81 Use of cigarette-smoking history to estimate the likelihood of mutations in epidermal growth factor receptor gene exons 19 and 21 in lung adenocarcinomas. J Clin Oncol 2006 2.58
82 PolyScan: an automatic indel and SNP detection approach to the analysis of human resequencing data. Genome Res 2007 2.58
83 Oil palm genome sequence reveals divergence of interfertile species in Old and New worlds. Nature 2013 2.58
84 A large and complex structural polymorphism at 16p12.1 underlies microdeletion disease risk. Nat Genet 2010 2.57
85 Analysis of the human neurexin genes: alternative splicing and the generation of protein diversity. Genomics 2002 2.54
86 Association of age at diagnosis and genetic mutations in patients with neuroblastoma. JAMA 2012 2.49
87 The Pediatric Cancer Genome Project. Nat Genet 2012 2.49
88 Novel MEK1 mutation identified by mutational analysis of epidermal growth factor receptor signaling pathway genes in lung adenocarcinoma. Cancer Res 2008 2.48
89 Evolution of human-specific neural SRGAP2 genes by incomplete segmental duplication. Cell 2012 2.43
90 Genome sequence of Cronobacter sakazakii BAA-894 and comparative genomic hybridization analysis with other Cronobacter species. PLoS One 2010 2.41
91 Challenges of sequencing human genomes. Brief Bioinform 2010 2.39
92 Human genome ultraconserved elements are ultraselected. Science 2007 2.34
93 Generation and annotation of the DNA sequences of human chromosomes 2 and 4. Nature 2005 2.27
94 DGIdb: mining the druggable genome. Nat Methods 2013 2.26
95 Mutational analysis of EGFR and related signaling pathway genes in lung adenocarcinomas identifies a novel somatic kinase domain mutation in FGFR4. PLoS One 2007 2.25
96 Cancer genome sequencing: a review. Hum Mol Genet 2009 2.15
97 Background mutations in parental cells account for most of the genetic heterogeneity of induced pluripotent stem cells. Cell Stem Cell 2012 2.11
98 Haplotype sorting using human fosmid clone end-sequence pairs. Genome Res 2008 2.10
99 The Oxytricha trifallax macronuclear genome: a complex eukaryotic genome with 16,000 tiny chromosomes. PLoS Biol 2013 2.08
100 Strict evolutionary conservation followed rapid gene loss on human and rhesus Y chromosomes. Nature 2012 2.06
101 The genome of Cyanothece 51142, a unicellular diazotrophic cyanobacterium important in the marine nitrogen cycle. Proc Natl Acad Sci U S A 2008 2.05
102 The draft genome of the parasitic nematode Trichinella spiralis. Nat Genet 2011 2.03
103 Conservation of Y-linked genes during human evolution revealed by comparative sequencing in chimpanzee. Nature 2005 1.97
104 The western painted turtle genome, a model for the evolution of extreme physiological adaptations in a slowly evolving lineage. Genome Biol 2013 1.87
105 A physical map of the chicken genome. Nature 2004 1.86
106 Sequence and comparative analysis of the maize NB mitochondrial genome. Plant Physiol 2004 1.83
107 Genomic impact of transient low-dose decitabine treatment on primary AML cells. Blood 2013 1.80
108 CMDS: a population-based method for identifying recurrent DNA copy number aberrations in cancer from high-resolution data. Bioinformatics 2009 1.73
109 The repetitive landscape of the chicken genome. Genome Res 2004 1.72
110 A pilot study of high-throughput, sequence-based mutational profiling of primary human acute myeloid leukemia cell genomes. Proc Natl Acad Sci U S A 2003 1.69
111 Sequencing a mouse acute promyelocytic leukemia genome reveals genetic events relevant for disease progression. J Clin Invest 2011 1.66
112 The physical and genetic framework of the maize B73 genome. PLoS Genet 2009 1.64
113 An Inv(16)(p13.3q24.3)-encoded CBFA2T3-GLIS2 fusion protein defines an aggressive subtype of pediatric acute megakaryoblastic leukemia. Cancer Cell 2012 1.61
114 Mutations of the SBDS gene are present in most patients with Shwachman-Diamond syndrome. Blood 2004 1.58
115 Identification of somatic JAK1 mutations in patients with acute myeloid leukemia. Blood 2007 1.55
116 Analysis of human mRNAs with the reference genome sequence reveals potential errors, polymorphisms, and RNA editing. Genome Res 2004 1.51
117 Genome sequence of enterovirus D68 from St. Louis, Missouri, USA. Emerg Infect Dis 2015 1.49
118 Gorilla genome structural variation reveals evolutionary parallelisms with chimpanzee. Genome Res 2011 1.47
119 Convergent evolution of chicken Z and human X chromosomes by expansion and gene acquisition. Nature 2010 1.46
120 PathScan: a tool for discerning mutational significance in groups of putative cancer genes. Bioinformatics 2011 1.46
121 Comparative genomics based on massive parallel transcriptome sequencing reveals patterns of substitution and selection across 10 bird species. Mol Ecol 2010 1.44
122 Reduced PU.1 expression causes myeloid progenitor expansion and increased leukemia penetrance in mice expressing PML-RARalpha. Proc Natl Acad Sci U S A 2005 1.43
123 The genome of the platyfish, Xiphophorus maculatus, provides insights into evolutionary adaptation and several complex traits. Nat Genet 2013 1.42
124 After the duplication: gene loss and adaptation in Saccharomyces genomes. Genetics 2005 1.40
125 Identification of a rare coding variant in complement 3 associated with age-related macular degeneration. Nat Genet 2013 1.39
126 What is finished, and why does it matter. Genome Res 2002 1.36
127 BreakFusion: targeted assembly-based identification of gene fusions in whole transcriptome paired-end sequencing data. Bioinformatics 2012 1.31
128 Chromothripsis and human disease: piecing together the shattering process. Cell 2012 1.30
129 Detailed analysis of a contiguous 22-Mb region of the maize genome. PLoS Genet 2009 1.29
130 Complete haplotype sequence of the human immunoglobulin heavy-chain variable, diversity, and joining genes and characterization of allelic and copy-number variation. Am J Hum Genet 2013 1.29
131 A vertebrate case study of the quality of assemblies derived from next-generation sequences. Genome Biol 2011 1.22
132 Sequencing human-gibbon breakpoints of synteny reveals mosaic new insertions at rearrangement sites. Genome Res 2008 1.21
133 Retrotransposition of gene transcripts leads to structural variation in mammalian genomes. Genome Biol 2013 1.20
134 Molecular refinement of gibbon genome rearrangements. Genome Res 2006 1.16
135 Nematode.net: a tool for navigating sequences from parasitic and free-living nematodes. Nucleic Acids Res 2004 1.16
136 Complete characterization of the microRNAome in a patient with acute myeloid leukemia. Blood 2010 1.16
137 Independent specialization of the human and mouse X chromosomes for the male germ line. Nat Genet 2013 1.15
138 Application of a superword array in genome assembly. Nucleic Acids Res 2006 1.14
139 A lover and a fighter: the genome sequence of an entomopathogenic nematode Heterorhabditis bacteriophora. PLoS One 2013 1.11
140 Physical map-assisted whole-genome shotgun sequence assemblies. Genome Res 2006 1.10
141 Genome of the house fly, Musca domestica L., a global vector of diseases with adaptations to a septic environment. Genome Biol 2014 1.08
142 Somatic mutations of PIK3R1 promote gliomagenesis. PLoS One 2012 1.06
143 A non-human primate system for large-scale genetic studies of complex traits. Hum Mol Genet 2012 1.05
144 Platypus globin genes and flanking loci suggest a new insertional model for beta-globin evolution in birds and mammals. BMC Biol 2008 1.03
145 Genomic pathology of SLE-associated copy-number variation at the FCGR2C/FCGR3B/FCGR2B locus. Am J Hum Genet 2012 1.02
146 Investigating hookworm genomes by comparative analysis of two Ancylostoma species. BMC Genomics 2005 1.02
147 Genomic landscapes and clonality of de novo AML. N Engl J Med 2013 1.01
148 Finished sequence and assembly of the DUF1220-rich 1q21 region using a haploid human genome. BMC Genomics 2014 0.99
149 Intestinal transcriptomes of nematodes: comparison of the parasites Ascaris suum and Haemonchus contortus with the free-living Caenorhabditis elegans. PLoS Negl Trop Dis 2008 0.98
150 Punctuated duplication seeding events during the evolution of human chromosome 2p11. Genome Res 2005 0.97
151 RB1 gene inactivation by chromothripsis in human retinoblastoma. Oncotarget 2014 0.96
152 The canine hookworm genome: analysis and classification of Ancylostoma caninum survey sequences. Mol Biochem Parasitol 2007 0.96
153 Massively parallel sequencing approaches for characterization of structural variation. Methods Mol Biol 2012 0.96
154 Assessing telomeric DNA content in pediatric cancers using whole-genome sequencing data. Genome Biol 2012 0.95
155 Novel venom gene discovery in the platypus. Genome Biol 2010 0.94
156 Characterizing Ancylostoma caninum transcriptome and exploring nematode parasitic adaptation. BMC Genomics 2010 0.93
157 Comparing low coverage random shotgun sequence data from Brassica oleracea and Oryza sativa genome sequence for their ability to add to the annotation of Arabidopsis thaliana. Genome Res 2005 0.92
158 Statistical aspects of discerning indel-type structural variation via DNA sequence alignment. BMC Genomics 2009 0.91
159 EAnnot: a genome annotation tool using experimental evidence. Genome Res 2004 0.90
160 Resolving the breakpoints of the 17q21.31 microdeletion syndrome with next-generation sequencing. Am J Hum Genet 2012 0.90
161 Has the chimpanzee Y chromosome been sequenced? Nat Genet 2006 0.89
162 Identification and analysis of genes expressed in the adult filarial parasitic nematode Dirofilaria immitis. Int J Parasitol 2006 0.88
163 The evolution of African great ape subtelomeric heterochromatin and the fusion of human chromosome 2. Genome Res 2012 0.87
164 Next-generation sequencing of cancer genomes: back to the future. Per Med 2009 0.86
165 Design and implementation of a generalized laboratory data model. BMC Bioinformatics 2007 0.86
166 Comprehensive genetic variant discovery in the surfactant protein B gene. Pediatr Res 2007 0.85
167 No bull: upholding community standards in public sharing of biological datasets. Proc Natl Acad Sci U S A 2013 0.85
168 BreakTrans: uncovering the genomic architecture of gene fusions. Genome Biol 2013 0.83
169 Transcriptomic analysis of the entomopathogenic nematode Heterorhabditis bacteriophora TTO1. BMC Genomics 2009 0.83
170 Molecular determinants archetypical to the phylum Nematoda. BMC Genomics 2009 0.80
171 Draft Genome Sequence of Acetobacter aceti Strain 1023, a Vinegar Factory Isolate. Genome Announc 2014 0.80
172 Genome science: a video tour of the Washington University Genome Sequencing Center for high school and undergraduate students. Cell Biol Educ 2005 0.79
173 The transcriptomes of the cattle parasitic nematode Ostertagia ostartagi. Vet Parasitol 2009 0.77
174 Correction: Tumor Evolution in Two Patients with Basal-like Breast Cancer: A Retrospective Genomics Study of Multiple Metastases. PLoS Med 2017 0.75
175 Corrigendum: The evolution of African great ape subtelomeric heterochromatin and the fusion of human chromosome 2. Genome Res 2017 0.75
176 Corrigendum: Whole genome analysis of a schistosomiasis-transmitting freshwater snail. Nat Commun 2017 0.75