Published in Lancet on January 11, 2012
Neolifes Heart - Pulmonary Hypertension in Preterm Children | NCT02729844
Observatory of Pulmonary Arterial Hypertension of Congenital Heart Disease (ItinerAir) | NCT02260362
Predictors of Catastrophic Adverse Outcomes in Children With Pulmonary Hypertension Undergoing Cardiac Catheterization: A Multi-Institutional Analysis From the Pediatric Health Information Systems Database. J Am Coll Cardiol (2015) 3.09
An official American Thoracic Society Statement: pulmonary hypertension phenotypes. Am J Respir Crit Care Med (2014) 1.02
Frontiers in pulmonary hypertension in infants and children with bronchopulmonary dysplasia. Pediatr Pulmonol (2012) 1.01
Right ventricular to left ventricular diameter ratio at end-systole in evaluating outcomes in children with pulmonary hypertension. J Am Soc Echocardiogr (2013) 0.97
Clinical trials in neonates and children: Report of the pulmonary hypertension academic research consortium pediatric advisory committee. Pulm Circ (2013) 0.94
Effectiveness and safety of inhaled treprostinil for the treatment of pulmonary arterial hypertension in children. Am J Cardiol (2012) 0.88
Drug treatment of pulmonary hypertension in children. Paediatr Drugs (2014) 0.86
Current challenges in pediatric pulmonary hypertension. Semin Respir Crit Care Med (2013) 0.85
Hemodynamic and genetic analysis in children with idiopathic, heritable, and congenital heart disease associated pulmonary arterial hypertension. Respir Res (2013) 0.85
Pulmonary hypertension: diagnostic and therapeutic challenges. Ther Clin Risk Manag (2015) 0.84
Pulmonary Arterial Hypertension among HIV-Infected Children: Results of a National Survey and Review of the Literature. Front Pediatr (2015) 0.82
Trends in pediatric pulmonary hypertension-related hospitalizations in the United States from 2000-2009. Pulm Circ (2015) 0.81
Evolving management of pediatric pulmonary arterial hypertension: impact of phosphodiesterase inhibitors. Pediatr Cardiol (2012) 0.79
TBX4 mutations (small patella syndrome) are associated with childhood-onset pulmonary arterial hypertension. J Med Genet (2013) 0.79
Systemic arterial endothelial function in children and young adults with idiopathic pulmonary arterial hypertension: is there a relation to pulmonary endothelium-dependent relaxation? Pediatr Cardiol (2014) 0.78
Progress in the diagnosis and management of pulmonary hypertension in children. Curr Opin Pediatr (2014) 0.78
Clinical classification in pediatric pulmonary arterial hypertension associated with congenital heart disease. Pulm Circ (2016) 0.78
Safety and tolerability of targeted therapies for pulmonary hypertension in children. Pediatr Cardiol (2013) 0.77
Sex differences in the pulmonary circulation: implications for pulmonary hypertension. Am J Physiol Heart Circ Physiol (2014) 0.77
Epidemiology and clinical management of pulmonary hypertension in children. Korean Circ J (2012) 0.77
Non-invasive determination by cardiovascular magnetic resonance of right ventricular-vascular coupling in children and adolescents with pulmonary hypertension. J Cardiovasc Magn Reson (2015) 0.77
Prevention of hyperoxia-induced bronchial hyperreactivity by sildenafil and vasoactive intestinal peptide: impact of preserved lung function and structure. Respir Res (2014) 0.76
Cardiovascular magnetic resonance catheterization derived pulmonary vascular resistance and medium-term outcomes in congenital heart disease. J Cardiovasc Magn Reson (2015) 0.76
Pulmonary arterial hypertension associated with congenital heart disease and Eisenmenger syndrome: current practice in pediatrics. Minerva Pediatr (2015) 0.76
Pulmonary hypertension in early life. Lancet (2012) 0.75
Safety and tolerability considerations in the use of sildenafil for children with pulmonary arterial hypertension. Drug Healthc Patient Saf (2015) 0.75
Transthoracic echocardiography in the evaluation of pediatric pulmonary hypertension and ventricular dysfunction. Pulm Circ (2016) 0.75
Interdisciplinary networks for the treatment of childhood pulmonary vascular disease: what pulmonary hypertension doctors can learn from pediatric oncologists. Pulm Circ (2013) 0.75
Evaluation of circulating proteins and hemodynamics towards predicting mortality in children with pulmonary arterial hypertension. PLoS One (2013) 0.75
Does intravenous sildenafil clinically ameliorate pulmonary hypertension during perioperative management of congenital heart diseases in children? - A prospective randomized study. Ann Card Anaesth (2015) 0.75
Pulmonary hypertension in the premature infant: a challenging comorbidity in a vulnerable population. Curr Opin Pediatr (2016) 0.75
Editorial: Pediatric Pulmonary Hypertension. Front Pediatr (2015) 0.75
Executive Summary of the American Heart Association and American Thoracic Society Joint Guidelines for Pediatric Pulmonary Hypertension. Am J Respir Crit Care Med (2016) 0.75
Pulmonary Hypertension in Children - a Practical Approach. Maedica (Buchar) (2015) 0.75
Learning a Comorbidity-Driven Taxonomy of Pediatric Pulmonary Hypertension. Circ Res (2017) 0.75
Hemodynamic Evaluation of Children with Persistent or Recurrent Pulmonary Arterial Hypertension Following Complete Repair of Congenital Heart Disease. Pediatr Cardiol (2017) 0.75
Addressing the challenges of phenotyping pediatric pulmonary vascular disease. Pulm Circ (2017) 0.75
A Computable Phenotype Improves Cohort Ascertainment in a Pediatric Pulmonary Hypertension Registry. J Pediatr (2017) 0.75
Oxidative injury of the pulmonary circulation in the perinatal period: Short- and long-term consequences for the human cardiopulmonary system. Pulm Circ (2017) 0.75
Home Exercise Training in Children and Adolescents with Pulmonary Arterial Hypertension: A Pilot Study. Pediatr Cardiol (2016) 0.75
Pulmonary hypertension's variegated landscape: a snapshot. Pulm Circ (2017) 0.75
Pulmonary arterial hypertension in the USA: an epidemiological study in a large insured pediatric population. Pulm Circ (2017) 0.75
Survival in patients with primary pulmonary hypertension. Results from a national prospective registry. Ann Intern Med (1991) 13.21
Updated clinical classification of pulmonary hypertension. J Am Coll Cardiol (2009) 12.05
Pulmonary arterial hypertension in France: results from a national registry. Am J Respir Crit Care Med (2006) 6.06
Clinical classification of pulmonary hypertension. J Am Coll Cardiol (2004) 5.87
Pulmonary arterial hypertension: baseline characteristics from the REVEAL Registry. Chest (2009) 4.08
Bosentan therapy in patients with Eisenmenger syndrome: a multicenter, double-blind, randomized, placebo-controlled study. Circulation (2006) 3.05
The changing picture of patients with pulmonary arterial hypertension in the United States: how REVEAL differs from historic and non-US Contemporary Registries. Chest (2010) 3.02
Pulmonary artery hypertension in formerly premature infants with bronchopulmonary dysplasia: clinical features and outcomes in the surfactant era. Pediatrics (2007) 2.47
Lung vascular development: implications for the pathogenesis of bronchopulmonary dysplasia. Annu Rev Physiol (2005) 2.46
The new bronchopulmonary dysplasia. Curr Opin Pediatr (2011) 2.24
Treatment and survival in children with pulmonary arterial hypertension: the UK Pulmonary Hypertension Service for Children 2001-2006. Heart (2008) 2.05
"Natural history" of pulmonary hypertension in a series of 131 patients with chronic obstructive lung disease. Am J Respir Crit Care Med (2001) 1.80
Pulmonary hypoplasia in Down's syndrome. N Engl J Med (1982) 1.69
Pediatric pulmonary hypertension in the Netherlands: epidemiology and characterization during the period 1991 to 2005. Circulation (2011) 1.54
Obstructive sleep apnea in children with Down syndrome. Pediatrics (1991) 1.53
Pulmonary complications of Down syndrome during childhood. J Pediatr (2010) 1.36
Pulmonary arterial hypertension: a comparison between children and adults. Eur Respir J (2011) 1.36
The pulmonary vascular bed in children with Down syndrome. J Pediatr (1975) 1.30
A randomized, placebo-controlled, double-blind, crossover study to evaluate the efficacy of oral sildenafil therapy in severe pulmonary artery hypertension. Am Heart J (2006) 1.26
Clinical characterization of pediatric pulmonary hypertension: complex presentation and diagnosis. J Pediatr (2009) 1.08
Long-term effect of bosentan in adults versus children with pulmonary arterial hypertension associated with systemic-to-pulmonary shunt: does the beneficial effect persist? Am Heart J (2007) 1.06
Pulmonary arterial hypertension in children: a medical update. Curr Opin Pediatr (2008) 0.94
Treatment options for paediatric pulmonary arterial hypertension. Eur Respir Rev (2010) 0.83
Syncope in adults with pulmonary arterial hypertension. J Am Coll Cardiol (2011) 0.83
Updated clinical classification of pulmonary hypertension. J Am Coll Cardiol (2009) 12.05
Oral rivaroxaban for the treatment of symptomatic pulmonary embolism. N Engl J Med (2012) 11.86
Bosentan therapy for pulmonary arterial hypertension. N Engl J Med (2002) 11.18
Oral rivaroxaban for symptomatic venous thromboembolism. N Engl J Med (2010) 9.92
Sildenafil citrate therapy for pulmonary arterial hypertension. N Engl J Med (2005) 9.27
Edoxaban versus warfarin for the treatment of symptomatic venous thromboembolism. N Engl J Med (2013) 7.76
Antithrombotic therapy for venous thromboembolic disease: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest (2008) 7.12
Oral apixaban for the treatment of acute venous thromboembolism. N Engl J Med (2013) 7.00
Antithrombotic therapy for venous thromboembolic disease: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest (2004) 5.96
Clinical classification of pulmonary hypertension. J Am Coll Cardiol (2004) 5.87
Riociguat for the treatment of pulmonary arterial hypertension. N Engl J Med (2013) 5.60
Apixaban versus enoxaparin for thromboprophylaxis after hip replacement. N Engl J Med (2010) 5.59
Human blood IgM "memory" B cells are circulating splenic marginal zone B cells harboring a prediversified immunoglobulin repertoire. Blood (2004) 5.10
Macitentan and morbidity and mortality in pulmonary arterial hypertension. N Engl J Med (2013) 4.98
Prospective trial of a pediatric ventricular assist device. N Engl J Med (2012) 4.72
Right ventricular function and failure: report of a National Heart, Lung, and Blood Institute working group on cellular and molecular mechanisms of right heart failure. Circulation (2006) 4.69
Predicting survival in pulmonary arterial hypertension: insights from the Registry to Evaluate Early and Long-Term Pulmonary Arterial Hypertension Disease Management (REVEAL). Circulation (2010) 4.66
Factor XI antisense oligonucleotide for prevention of venous thrombosis. N Engl J Med (2014) 4.58
Apixaban for extended treatment of venous thromboembolism. N Engl J Med (2012) 4.37
Pulmonary arterial hypertension: baseline characteristics from the REVEAL Registry. Chest (2009) 4.08
Continuous subcutaneous infusion of treprostinil, a prostacyclin analogue, in patients with pulmonary arterial hypertension: a double-blind, randomized, placebo-controlled trial. Am J Respir Crit Care Med (2002) 3.91
Idraparinux versus standard therapy for venous thromboembolic disease. N Engl J Med (2007) 3.64
Apixaban versus enoxaparin for thromboprophylaxis after knee replacement (ADVANCE-2): a randomised double-blind trial. Lancet (2010) 3.29
Addition of sildenafil to long-term intravenous epoprostenol therapy in patients with pulmonary arterial hypertension: a randomized trial. Ann Intern Med (2008) 3.13
Bosentan therapy in patients with Eisenmenger syndrome: a multicenter, double-blind, randomized, placebo-controlled study. Circulation (2006) 3.05
The changing picture of patients with pulmonary arterial hypertension in the United States: how REVEAL differs from historic and non-US Contemporary Registries. Chest (2010) 3.02
Tadalafil therapy for pulmonary arterial hypertension. Circulation (2009) 2.98
Effects of long-term bosentan in children with pulmonary arterial hypertension. J Am Coll Cardiol (2005) 2.91
Apixaban or enoxaparin for thromboprophylaxis after knee replacement. N Engl J Med (2009) 2.90
An evaluation of long-term survival from time of diagnosis in pulmonary arterial hypertension from the REVEAL Registry. Chest (2012) 2.82
New predictors of outcome in idiopathic pulmonary arterial hypertension. Am J Cardiol (2005) 2.81
Oestradiol ameliorates monocrotaline pulmonary hypertension via NO, prostacyclin and endothelin-1 pathways. Eur Respir J (2012) 2.72
Imatinib mesylate as add-on therapy for pulmonary arterial hypertension: results of the randomized IMPRES study. Circulation (2013) 2.64
Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiency. Nat Immunol (2012) 2.38
A randomized, double-blind, placebo-controlled, dose-ranging study of oral sildenafil citrate in treatment-naive children with pulmonary arterial hypertension. Circulation (2011) 2.32
Prognostic significance of 2-dimensional, M-mode, and Doppler echo indices of right ventricular function in children with pulmonary arterial hypertension. Am Heart J (2013) 2.32
Oral thrombin inhibitor dabigatran etexilate vs North American enoxaparin regimen for prevention of venous thromboembolism after knee arthroplasty surgery. J Arthroplasty (2008) 2.30
Clinical utility of D-dimer in patients with suspected pulmonary embolism and nondiagnostic lung scans or negative CT findings. Chest (2004) 2.30
Prevention and treatment of thrombosis in pediatric and congenital heart disease: a scientific statement from the American Heart Association. Circulation (2013) 2.24
An official American Thoracic Society clinical practice guideline: diagnosis, risk stratification, and management of pulmonary hypertension of sickle cell disease. Am J Respir Crit Care Med (2014) 2.23
Oral rivaroxaban versus standard therapy for the treatment of symptomatic venous thromboembolism: a pooled analysis of the EINSTEIN-DVT and PE randomized studies. Thromb J (2013) 2.21
Physical activity reduces systemic blood pressure and improves early markers of atherosclerosis in pre-pubertal obese children. J Am Coll Cardiol (2009) 2.18
Kinetics of the utilization of dietary arginine for nitric oxide and urea synthesis: insight into the arginine-nitric oxide metabolic system in humans. Am J Clin Nutr (2013) 2.16
Comparison of the profiles of postoperative systemic hemodynamics and oxygen transport in neonates after the hybrid or the Norwood procedure: a pilot study. Circulation (2007) 2.16
The hemodynamic response to dexmedetomidine loading dose in children with and without pulmonary hypertension. Anesth Analg (2013) 2.12
Magnetic resonance imaging analysis of right ventricular pressure-volume loops: in vivo validation and clinical application in patients with pulmonary hypertension. Circulation (2004) 2.12
Hypoplastic left heart syndrome: current considerations and expectations. J Am Coll Cardiol (2012) 2.10
Homografts and xenografts for right ventricular outflow tract reconstruction: long-term results. Ann Thorac Surg (2010) 2.09
The phosphodiesterase-5 inhibitor vardenafil reduces oxidative stress while reversing pulmonary arterial hypertension. Cardiovasc Res (2013) 2.08
Berlin Heart EXCOR pediatric ventricular assist device for bridge to heart transplantation in US children. Circulation (2013) 2.07
Bloodstream infections in patients given treatment with intravenous prostanoids. Infect Control Hosp Epidemiol (2008) 2.03
Bridging children of all sizes to cardiac transplantation: the initial multicenter North American experience with the Berlin Heart EXCOR ventricular assist device. J Heart Lung Transplant (2011) 2.03
Portopulmonary hypertension in pediatric patients. J Pediatr (2005) 2.03
Unknown complication of arterial switch operation: resistant hypertension induced by a strong aortic arch angulation. Circulation (2013) 2.02
Associations among obesity, blood pressure, and left ventricular mass. J Pediatr (2007) 2.01
Medical therapy for pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines. Chest (2004) 2.00
Attenuation of acute hypoxic pulmonary vasoconstriction and hypoxic pulmonary hypertension in mice by inhibition of Rho-kinase. Am J Physiol Lung Cell Mol Physiol (2004) 1.90
Diagnosis and outcome in congenital ventricular diverticulum and aneurysm. J Thorac Cardiovasc Surg (2006) 1.88
Randomized study of adding inhaled iloprost to existing bosentan in pulmonary arterial hypertension. Am J Respir Crit Care Med (2006) 1.86
STARTS-2: long-term survival with oral sildenafil monotherapy in treatment-naive pediatric pulmonary arterial hypertension. Circulation (2014) 1.86
Extended prophylaxis of venous thromboembolism with idraparinux. N Engl J Med (2007) 1.84
Dosing of clopidogrel for platelet inhibition in infants and young children: primary results of the Platelet Inhibition in Children On cLOpidogrel (PICOLO) trial. Circulation (2008) 1.82
Late systemic hypertension and aortic arch geometry after successful repair of coarctation of the aorta. Eur Heart J (2004) 1.78
ADAMTSL2 mutations in geleophysic dysplasia demonstrate a role for ADAMTS-like proteins in TGF-beta bioavailability regulation. Nat Genet (2008) 1.78
Clinical utility of echocardiography for the diagnosis and management of pulmonary vascular disease in young children with chronic lung disease. Pediatrics (2008) 1.77
Mutation in myosin heavy chain 6 causes atrial septal defect. Nat Genet (2005) 1.76
Complications of right heart catheterization procedures in patients with pulmonary hypertension in experienced centers. J Am Coll Cardiol (2006) 1.76
Angular (Gothic) aortic arch leads to enhanced systolic wave reflection, central aortic stiffness, and increased left ventricular mass late after aortic coarctation repair: evaluation with magnetic resonance flow mapping. J Thorac Cardiovasc Surg (2008) 1.75
Executive function and theory of mind in school-aged children after neonatal corrective cardiac surgery for transposition of the great arteries. Dev Med Child Neurol (2010) 1.74
Selective endothelin A receptor antagonism with sitaxsentan for pulmonary arterial hypertension associated with connective tissue disease. Ann Rheum Dis (2007) 1.72
The relationship between the severity of hemolysis, clinical manifestations and risk of death in 415 patients with sickle cell anemia in the US and Europe. Haematologica (2012) 1.72
Outcome after cardiopulmonary resuscitation in patients with pulmonary arterial hypertension. Am J Respir Crit Care Med (2002) 1.72
Trends in prenatal diagnosis, pregnancy termination, and perinatal mortality of newborns with congenital heart disease in France, 1983-2000: a population-based evaluation. Pediatrics (2005) 1.72
Treprostinil, a prostacyclin analogue, in pulmonary arterial hypertension associated with connective tissue disease. Chest (2004) 1.72
Imatinib in pulmonary arterial hypertension patients with inadequate response to established therapy. Am J Respir Crit Care Med (2010) 1.69
Percutaneous pulmonary valve replacement in a large right ventricular outflow tract: an experimental study. J Am Coll Cardiol (2004) 1.67
Survival in childhood pulmonary arterial hypertension: insights from the registry to evaluate early and long-term pulmonary arterial hypertension disease management. Circulation (2011) 1.67
Usefulness of the right ventricular systolic to diastolic duration ratio to predict functional capacity and survival in children with pulmonary arterial hypertension. Am J Cardiol (2010) 1.66
Impact of prenatal diagnosis on neurocognitive outcomes in children with transposition of the great arteries. J Pediatr (2012) 1.65
Safety and efficacy of IV treprostinil for pulmonary arterial hypertension: a prospective, multicenter, open-label, 12-week trial. Chest (2006) 1.64
Hospitalization for pain in patients with sickle cell disease treated with sildenafil for elevated TRV and low exercise capacity. Blood (2011) 1.64
Clinical outcomes of palliative surgery including a systemic-to-pulmonary artery shunt in infants with cyanotic congenital heart disease: does aspirin make a difference? Circulation (2007) 1.64
Diagnostic evaluation of paediatric pulmonary hypertension in current clinical practice. Eur Respir J (2013) 1.62
Outcome of extracorporeal membrane oxygenation for early primary graft failure after pediatric heart transplantation. J Am Coll Cardiol (2009) 1.61