Published in PLoS Genet on January 12, 2012
Inference of population splits and mixtures from genome-wide allele frequency data. PLoS Genet (2012) 4.85
The geography of recent genetic ancestry across Europe. PLoS Biol (2013) 3.44
New insights into the Tyrolean Iceman's origin and phenotype as inferred by whole-genome sequencing. Nat Commun (2012) 3.18
A genetic atlas of human admixture history. Science (2014) 3.09
Fast and accurate inference of local ancestry in Latino populations. Bioinformatics (2012) 2.30
Population genetics models of local ancestry. Genetics (2012) 2.10
Genetic ancestry of a Moroccan population as inferred from autosomal STRs. Meta Gene (2014) 2.08
The great human expansion. Proc Natl Acad Sci U S A (2012) 1.86
Gene flow from North Africa contributes to differential human genetic diversity in southern Europe. Proc Natl Acad Sci U S A (2013) 1.77
Population genetic inference from personal genome data: impact of ancestry and admixture on human genomic variation. Am J Hum Genet (2012) 1.75
Age of the association between Helicobacter pylori and man. PLoS Pathog (2012) 1.62
Untangling the hybrid nature of modern pig genomes: a mosaic derived from biogeographically distinct and highly divergent Sus scrofa populations. Mol Ecol (2014) 1.61
Ethiopian genetic diversity reveals linguistic stratification and complex influences on the Ethiopian gene pool. Am J Hum Genet (2012) 1.60
Human genetics. The genetics of Mexico recapitulates Native American substructure and affects biomedical traits. Science (2014) 1.42
Genetic origins of lactase persistence and the spread of pastoralism in Africa. Am J Hum Genet (2014) 1.27
Introgression of Neandertal- and Denisovan-like Haplotypes Contributes to Adaptive Variation in Human Toll-like Receptors. Am J Hum Genet (2016) 1.23
Maritime route of colonization of Europe. Proc Natl Acad Sci U S A (2014) 1.20
Genome-wide genotype and sequence-based reconstruction of the 140,000 year history of modern human ancestry. Sci Rep (2014) 1.11
Genomic insights into the origin of farming in the ancient Near East. Nature (2016) 1.07
Toward a new history and geography of human genes informed by ancient DNA. Trends Genet (2014) 1.07
Distance from sub-Saharan Africa predicts mutational load in diverse human genomes. Proc Natl Acad Sci U S A (2015) 1.06
Early back-to-Africa migration into the Horn of Africa. PLoS Genet (2014) 1.06
The lengths of admixture tracts. Genetics (2014) 1.06
Evaluating the use of ABBA-BABA statistics to locate introgressed loci. Mol Biol Evol (2014) 1.05
North African Jewish and non-Jewish populations form distinctive, orthogonal clusters. Proc Natl Acad Sci U S A (2012) 1.05
Chromosome painting in silico in a bacterial species reveals fine population structure. Mol Biol Evol (2013) 1.05
Serum vitamin D3 level inversely correlates with uterine fibroid volume in different ethnic groups: a cross-sectional observational study. Int J Womens Health (2013) 1.00
The first modern human dispersals across Africa. PLoS One (2013) 1.00
Tracing the route of modern humans out of Africa by using 225 human genome sequences from Ethiopians and Egyptians. Am J Hum Genet (2015) 1.00
Characterization of Greater Middle Eastern genetic variation for enhanced disease gene discovery. Nat Genet (2016) 0.97
Genetic variation and adaptation in Africa: implications for human evolution and disease. Cold Spring Harb Perspect Biol (2014) 0.94
Genomic Insights into the Ancestry and Demographic History of South America. PLoS Genet (2015) 0.93
North African populations carry the signature of admixture with Neandertals. PLoS One (2012) 0.92
Introducing the Algerian mitochondrial DNA and Y-chromosome profiles into the North African landscape. PLoS One (2013) 0.91
Overview of admixture mapping. Curr Protoc Hum Genet (2013) 0.88
Inference of historical migration rates via haplotype sharing. Bioinformatics (2013) 0.87
Genome-wide and paternal diversity reveal a recent origin of human populations in North Africa. PLoS One (2013) 0.86
Determining ancestry proportions in complex admixture scenarios in South Africa using a novel proxy ancestry selection method. PLoS One (2013) 0.85
Extreme population differences in the human zinc transporter ZIP4 (SLC39A4) are explained by positive selection in Sub-Saharan Africa. PLoS Genet (2014) 0.84
Ancestry inference in complex admixtures via variable-length Markov chain linkage models. J Comput Biol (2013) 0.84
Divorcing the Late Upper Palaeolithic demographic histories of mtDNA haplogroups M1 and U6 in Africa. BMC Evol Biol (2012) 0.83
Deciphering the fine-structure of tribal admixture in the Bedouin population using genomic data. Heredity (Edinb) (2013) 0.83
Early modern human dispersal from Africa: genomic evidence for multiple waves of migration. Investig Genet (2015) 0.83
Early Holocenic and Historic mtDNA African Signatures in the Iberian Peninsula: The Andalusian Region as a Paradigm. PLoS One (2015) 0.82
Balancing selection on a regulatory region exhibiting ancient variation that predates human-neandertal divergence. PLoS Genet (2013) 0.81
The genetics of East African populations: a Nilo-Saharan component in the African genetic landscape. Sci Rep (2015) 0.81
A Spatial Framework for Understanding Population Structure and Admixture. PLoS Genet (2016) 0.81
Mapping the genomic mosaic of two 'Afro-Bolivians' from the isolated Yungas valleys. BMC Genomics (2016) 0.80
Human Dispersal Out of Africa: A Lasting Debate. Evol Bioinform Online (2016) 0.80
Are polymorphisms of the immunoregulatory factor CD40LG implicated in acute transfusion reactions? Sci Rep (2014) 0.80
The peopling of the African continent and the diaspora into the new world. Curr Opin Genet Dev (2014) 0.79
Global patterns of diversity and selection in human tyrosinase gene. PLoS One (2013) 0.79
Analysis of Genomic Regions Associated With Coronary Artery Disease Reveals Continent-Specific Single Nucleotide Polymorphisms in North African Populations. J Epidemiol (2016) 0.78
Complex Ancestries of Lager-Brewing Hybrids Were Shaped by Standing Variation in the Wild Yeast Saccharomyces eubayanus. PLoS Genet (2016) 0.78
Novel Mutations Causing C5 Deficiency in Three North-African Families. J Clin Immunol (2016) 0.77
Across language families: Genome diversity mirrors linguistic variation within Europe. Am J Phys Anthropol (2015) 0.77
Genetic Heterogeneity in Algerian Human Populations. PLoS One (2015) 0.77
Carriers of Mitochondrial DNA Macrohaplogroup N Lineages Reached Australia around 50,000 Years Ago following a Northern Asian Route. PLoS One (2015) 0.77
Admixture into and within sub-Saharan Africa. Elife (2016) 0.77
Genome scan study of prostate cancer in Arabs: identification of three genomic regions with multiple prostate cancer susceptibility loci in Tunisians. J Transl Med (2013) 0.77
Y-chromosome E haplogroups: their distribution and implication to the origin of Afro-Asiatic languages and pastoralism. Eur J Hum Genet (2014) 0.77
Complex Ancient Genetic Structure and Cultural Transitions in Southern African Populations. Genetics (2016) 0.76
The interplay between natural selection and susceptibility to melanoma on allele 374F of SLC45A2 gene in a South European population. PLoS One (2014) 0.76
Inferring ancestry from population genomic data and its applications. Front Genet (2014) 0.76
Impact of GGCX, STX1B and FPGS Polymorphisms on Warfarin Dose Requirements in European-Americans and Egyptians. Clin Transl Sci (2016) 0.76
Constraint, natural selection, and the evolution of human body form. Proc Natl Acad Sci U S A (2016) 0.75
Genetic variation in Tunisia in the context of human diversity worldwide. Am J Phys Anthropol (2016) 0.75
Reassessing the Evolutionary History of the 17q21 Inversion Polymorphism. Genome Biol Evol (2015) 0.75
The TCF7L2 rs7903146 polymorphism, dietary intakes and type 2 diabetes risk in an Algerian population. BMC Genet (2014) 0.75
A survey of sub-Saharan gene flow into the Mediterranean at risk loci for coronary artery disease. Eur J Hum Genet (2017) 0.75
Genomic continuity of Argentinean Mennonites. Sci Rep (2016) 0.75
Migration Route Out of Africa Unresolved by 225 Egyptian and Ethiopian Whole Genome Sequences. Front Genet (2016) 0.75
A Hidden Markov Model Approach for Simultaneously Estimating Local Ancestry and Admixture Time Using Next Generation Sequence Data in Samples of Arbitrary Ploidy. PLoS Genet (2017) 0.75
Human ancestry correlates with language and reveals that race is not an objective genomic classifier. Sci Rep (2017) 0.75
Treating infants with frigg: linking disease aetiologies, medicinal plant use and care-seeking behaviour in southern Morocco. J Ethnobiol Ethnomed (2017) 0.75
Impact of Genetic Polymorphisms on Phenytoin Pharmacokinetics and Clinical Outcomes in the Middle East and North Africa Region. Drugs R D (2017) 0.75
Ancient selection for derived alleles at a GDF5 enhancer influencing human growth and osteoarthritis risk. Nat Genet (2017) 0.75
Northeast African genomic variation shaped by the continuity of indigenous groups and Eurasian migrations. PLoS Genet (2017) 0.75
Evidence for prehistoric origins of the G2019S mutation in the North African Berber population. PLoS One (2017) 0.75
PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet (2007) 209.92
Integrating common and rare genetic variation in diverse human populations. Nature (2010) 32.30
Rapid and accurate haplotype phasing and missing-data inference for whole-genome association studies by use of localized haplotype clustering. Am J Hum Genet (2007) 24.68
Worldwide human relationships inferred from genome-wide patterns of variation. Science (2008) 22.44
Fast model-based estimation of ancestry in unrelated individuals. Genome Res (2009) 15.63
A worldwide survey of haplotype variation and linkage disequilibrium in the human genome. Nat Genet (2006) 8.46
Sensitive detection of chromosomal segments of distinct ancestry in admixed populations. PLoS Genet (2009) 6.36
Reconstructing genetic ancestry blocks in admixed individuals. Am J Hum Genet (2006) 5.92
Estimating local ancestry in admixed populations. Am J Hum Genet (2008) 5.90
Genome-wide patterns of population structure and admixture in West Africans and African Americans. Proc Natl Acad Sci U S A (2009) 5.39
Genetics in geographically structured populations: defining, estimating and interpreting F(ST). Nat Rev Genet (2009) 5.23
Whole population, genome-wide mapping of hidden relatedness. Genome Res (2008) 4.72
Hunter-gatherer genomic diversity suggests a southern African origin for modern humans. Proc Natl Acad Sci U S A (2011) 3.53
New estimates of intergenerational time intervals for the calculation of age and origins of mutations. Am J Hum Genet (2000) 3.47
Colloquium paper: genome-wide patterns of population structure and admixture among Hispanic/Latino populations. Proc Natl Acad Sci U S A (2010) 3.20
The mtDNA legacy of the Levantine early Upper Palaeolithic in Africa. Science (2006) 2.98
The history of African gene flow into Southern Europeans, Levantines, and Jews. PLoS Genet (2011) 2.81
Inferring human colonization history using a copying model. PLoS Genet (2008) 2.64
Ascertainment biases in SNP chips affect measures of population divergence. Mol Biol Evol (2010) 2.56
Inference of historical changes in migration rate from the lengths of migrant tracts. Genetics (2008) 2.53
Geographical genomics of human leukocyte gene expression variation in southern Morocco. Nat Genet (2009) 2.38
High-resolution analysis of human Y-chromosome variation shows a sharp discontinuity and limited gene flow between northwestern Africa and the Iberian Peninsula. Am J Hum Genet (2001) 2.32
Genome-wide association study implicates chromosome 9q21.31 as a susceptibility locus for asthma in mexican children. PLoS Genet (2009) 2.27
New approaches to disease mapping in admixed populations. Nat Rev Genet (2011) 2.22
A predominantly neolithic origin for Y-chromosomal DNA variation in North Africa. Am J Hum Genet (2004) 2.02
Characterizing the admixed African ancestry of African Americans. Genome Biol (2009) 2.01
Population genetic structure of the people of Qatar. Am J Hum Genet (2010) 1.91
Evolutionary and functional analysis of celiac risk loci reveals SH2B3 as a protective factor against bacterial infection. Am J Hum Genet (2010) 1.71
History shaped the geographic distribution of genomic admixture on the island of Puerto Rico. PLoS One (2011) 1.50
Mitochondrial DNA transit between West Asia and North Africa inferred from U6 phylogeography. BMC Genet (2003) 1.50
Identifying genetic traces of historical expansions: Phoenician footprints in the Mediterranean. Am J Hum Genet (2008) 1.50
Human Y chromosome haplogroup R-V88: a paternal genetic record of early mid Holocene trans-Saharan connections and the spread of Chadic languages. Eur J Hum Genet (2010) 1.47
Alu insertion polymorphisms in NW Africa and the Iberian Peninsula: evidence for a strong genetic boundary through the Gibraltar Straits. Hum Genet (2000) 1.38
Genetic variation in North Africa and Eurasia: neolithic demic diffusion vs. Paleolithic colonisation. Am J Phys Anthropol (1994) 1.31
Genetic admixture, self-reported ethnicity, self-estimated admixture, and skin pigmentation among Hispanics and Native Americans. Am J Phys Anthropol (2009) 1.26
High-density SNP genotyping detects homogeneity of Spanish and French Basques, and confirms their genomic distinctiveness from other European populations. Hum Genet (2010) 1.13
The trans-Saharan slave trade - clues from interpolation analyses and high-resolution characterization of mitochondrial DNA lineages. BMC Evol Biol (2010) 1.13
Population history of north Africa: evidence from classical genetic markers. Hum Biol (1997) 1.10
Molecular analyses of the LRRK2 gene in European and North African autosomal dominant Parkinson's disease. J Med Genet (2009) 1.01
Mitochondrial DNA structure in North Africa reveals a genetic discontinuity in the Nile Valley. Am J Phys Anthropol (2011) 0.98
Temporal mitochondrial DNA variation in the Basque Country: influence of post-neolithic events. Ann Hum Genet (2005) 0.96
Parkinson's disease-related LRRK2 G2019S mutation results from independent mutational events in humans. Hum Mol Genet (2010) 0.87
Comprehensive sequencing of the LRRK2 gene in patients with familial Parkinson's disease from North Africa. Mov Disord (2010) 0.81
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
Scalable molecular dynamics with NAMD. J Comput Chem (2005) 59.49
The diploid genome sequence of an Asian individual. Nature (2008) 46.29
Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome. Nat Genet (2007) 32.41
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
Evolution and functional impact of rare coding variation from deep sequencing of human exomes. Science (2012) 17.12
Evolutionary and biomedical insights from the rhesus macaque genome. Science (2007) 16.21
Genes mirror geography within Europe. Nature (2008) 14.23
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. Nat Genet (2008) 12.51
piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells. Nature (2009) 11.27
Sequencing of 50 human exomes reveals adaptation to high altitude. Science (2010) 11.27
Inferring the joint demographic history of multiple populations from multidimensional SNP frequency data. PLoS Genet (2009) 9.16
Assessing the evolutionary impact of amino acid mutations in the human genome. PLoS Genet (2008) 8.92
Distinct epigenomic landscapes of pluripotent and lineage-committed human cells. Cell Stem Cell (2010) 8.74
A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen. Cancer Cell (2004) 8.06
Automatic atom type and bond type perception in molecular mechanical calculations. J Mol Graph Model (2006) 7.93
Genome-wide survey of SNP variation uncovers the genetic structure of cattle breeds. Science (2009) 7.64
Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming. Nat Biotechnol (2009) 7.59
Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet (2012) 7.59
Demographic history and rare allele sharing among human populations. Proc Natl Acad Sci U S A (2011) 7.36
Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism. Cell (2012) 7.36
Acute renal failure and sepsis. N Engl J Med (2004) 7.18
The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models. Nat Biotechnol (2010) 7.08
High-performance neuroprosthetic control by an individual with tetraplegia. Lancet (2012) 6.66
Ascertainment bias in studies of human genome-wide polymorphism. Genome Res (2005) 6.63
Proportionally more deleterious genetic variation in European than in African populations. Nature (2008) 6.61
Simultaneous inference of selection and population growth from patterns of variation in the human genome. Proc Natl Acad Sci U S A (2005) 5.94
The dog genome: survey sequencing and comparative analysis. Science (2003) 5.84
New loci associated with kidney function and chronic kidney disease. Nat Genet (2010) 5.58
Antitumor activity of rapamycin in a Phase I trial for patients with recurrent PTEN-deficient glioblastoma. PLoS Med (2008) 5.54
The draft genome of the transgenic tropical fruit tree papaya (Carica papaya Linnaeus). Nature (2008) 5.54
Genome-wide association mapping reveals a rich genetic architecture of complex traits in Oryza sativa. Nat Commun (2011) 5.41
Genome-wide patterns of population structure and admixture in West Africans and African Americans. Proc Natl Acad Sci U S A (2009) 5.39
Predictive value for the Chinese population of the Framingham CHD risk assessment tool compared with the Chinese Multi-Provincial Cohort Study. JAMA (2004) 5.34
The oyster genome reveals stress adaptation and complexity of shell formation. Nature (2012) 5.30
De novo mutations in histone-modifying genes in congenital heart disease. Nature (2013) 5.15
Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals. J Exp Med (2008) 5.14
Localizing recent adaptive evolution in the human genome. PLoS Genet (2007) 5.11
Correlation between genetic and geographic structure in Europe. Curr Biol (2008) 5.02
MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth. Cancer Res (2007) 4.95
An Aboriginal Australian genome reveals separate human dispersals into Asia. Science (2011) 4.84
The Population Reference Sample, POPRES: a resource for population, disease, and pharmacological genetics research. Am J Hum Genet (2008) 4.79
Patterns of positive selection in six Mammalian genomes. PLoS Genet (2008) 4.69
A single IGF1 allele is a major determinant of small size in dogs. Science (2007) 4.68
Genomewide SNP variation reveals relationships among landraces and modern varieties of rice. Proc Natl Acad Sci U S A (2009) 4.65
Genome-wide SNP and haplotype analyses reveal a rich history underlying dog domestication. Nature (2010) 4.64
ClinGen--the Clinical Genome Resource. N Engl J Med (2015) 4.45
The functional spectrum of low-frequency coding variation. Genome Biol (2011) 4.42
A Markov chain Monte Carlo approach for joint inference of population structure and inbreeding rates from multilocus genotype data. Genetics (2007) 4.31
Hepatocyte growth factor induces gefitinib resistance of lung adenocarcinoma with epidermal growth factor receptor-activating mutations. Cancer Res (2008) 4.30
EpCAM and alpha-fetoprotein expression defines novel prognostic subtypes of hepatocellular carcinoma. Cancer Res (2008) 4.17
Probable limited person-to-person transmission of highly pathogenic avian influenza A (H5N1) virus in China. Lancet (2008) 4.17
Molecular and evolutionary history of melanism in North American gray wolves. Science (2009) 3.87
Pelvic Organ Support Study (POSST): the distribution, clinical definition, and epidemiologic condition of pelvic organ support defects. Am J Obstet Gynecol (2005) 3.85
Genome-wide patterns of nucleotide polymorphism in domesticated rice. PLoS Genet (2007) 3.83
Comparative and demographic analysis of orang-utan genomes. Nature (2011) 3.83
Association between adverse clinical outcome in human disease caused by novel influenza A H7N9 virus and sustained viral shedding and emergence of antiviral resistance. Lancet (2013) 3.83
Epigenomic analysis of multilineage differentiation of human embryonic stem cells. Cell (2013) 3.81
Epidemiological transition of stroke in China: twenty-one-year observational study from the Sino-MONICA-Beijing Project. Stroke (2008) 3.81
Natural selection on EPAS1 (HIF2alpha) associated with low hemoglobin concentration in Tibetan highlanders. Proc Natl Acad Sci U S A (2010) 3.78
Acute renal failure: definitions, diagnosis, pathogenesis, and therapy. J Clin Invest (2004) 3.75
Discovery and annotation of functional chromatin signatures in the human genome. PLoS Comput Biol (2009) 3.61
A mutation in the myostatin gene increases muscle mass and enhances racing performance in heterozygote dogs. PLoS Genet (2007) 3.61
The dawn of human matrilineal diversity. Am J Hum Genet (2008) 3.60
Residential proximity to naturally occurring asbestos and mesothelioma risk in California. Am J Respir Crit Care Med (2005) 3.55
Clinical application of massively parallel sequencing-based prenatal noninvasive fetal trisomy test for trisomies 21 and 18 in 11,105 pregnancies with mixed risk factors. Prenat Diagn (2012) 3.54
Hunter-gatherer genomic diversity suggests a southern African origin for modern humans. Proc Natl Acad Sci U S A (2011) 3.53
Surgical treatment of giant coronary artery aneurysm. J Thorac Cardiovasc Surg (2005) 3.53
ChromaSig: a probabilistic approach to finding common chromatin signatures in the human genome. PLoS Comput Biol (2008) 3.46
A simple genetic architecture underlies morphological variation in dogs. PLoS Biol (2010) 3.46
A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates. Proc Natl Acad Sci U S A (2009) 3.39
The derived FOXP2 variant of modern humans was shared with Neandertals. Curr Biol (2007) 3.39
The genome-wide structure of the Jewish people. Nature (2010) 3.37
Characteristics associated with differences in survival among black and white women with breast cancer. JAMA (2013) 3.35
Effects of acupuncture on pregnancy rates in women undergoing in vitro fertilization: a systematic review and meta-analysis. Fertil Steril (2012) 3.33
An expressed fgf4 retrogene is associated with breed-defining chondrodysplasia in domestic dogs. Science (2009) 3.29
Genetic analysis of complex traits in the emerging Collaborative Cross. Genome Res (2011) 3.25
Effects of a universal classroom behavior management program in first and second grades on young adult behavioral, psychiatric, and social outcomes. Drug Alcohol Depend (2008) 3.22
Colloquium paper: genome-wide patterns of population structure and admixture among Hispanic/Latino populations. Proc Natl Acad Sci U S A (2010) 3.20
Phased whole-genome genetic risk in a family quartet using a major allele reference sequence. PLoS Genet (2011) 3.20
New insights into the Tyrolean Iceman's origin and phenotype as inferred by whole-genome sequencing. Nat Commun (2012) 3.18
Allele-specific methylation is prevalent and is contributed by CpG-SNPs in the human genome. Genome Res (2010) 3.17
Transcriptome profiling of human and murine ESCs identifies divergent paths required to maintain the stem cell state. Stem Cells (2005) 3.16
A recalibrated molecular clock and independent origins for the cholera pandemic clones. PLoS One (2008) 3.16
Effectiveness of strengthened stimulation during acupuncture for the treatment of Bell palsy: a randomized controlled trial. CMAJ (2013) 3.15
Methods for testing theory and evaluating impact in randomized field trials: intent-to-treat analyses for integrating the perspectives of person, place, and time. Drug Alcohol Depend (2008) 3.09
The origin of European cattle: evidence from modern and ancient DNA. Proc Natl Acad Sci U S A (2006) 3.09
Quantum-sized carbon dots for bright and colorful photoluminescence. J Am Chem Soc (2006) 3.08
Adverse metabolic consequences in humans of prolonged sleep restriction combined with circadian disruption. Sci Transl Med (2012) 3.08