Published in J Ethnopharmacol on January 14, 2012
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Hedyotis diffusa Willd. extract suppresses proliferation and induces apoptosis via IL-6-inducible STAT3 pathway inactivation in human colorectal cancer cells. Oncol Lett (2015) 0.89
Anti-inflammatory and anti-cancer activity of mulberry (Morus alba L.) root bark. BMC Complement Altern Med (2014) 0.89
Protection against Cancer with Medicinal Herbs via Activation of Tumor Suppressor. J Oncol (2012) 0.85
PP2A inhibitors arrest G2/M transition through JNK/Sp1- dependent down-regulation of CDK1 and autophagy-dependent up-regulation of p21. Oncotarget (2015) 0.84
Combination treatment with triptolide and hydroxycamptothecin synergistically enhances apoptosis in A549 lung adenocarcinoma cells through PP2A-regulated ERK, p38 MAPKs and Akt signaling pathways. Int J Oncol (2015) 0.83
In vitro anti-proliferative effects of Zuojinwan on eight kinds of human cancer cell lines. Cytotechnology (2013) 0.82
Scutellaria barbata D. Don inhibits growth and induces apoptosis by suppressing IL-6-inducible STAT3 pathway activation in human colorectal cancer cells. Exp Ther Med (2015) 0.81
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Non-ionic surfactant vesicles simultaneously enhance antitumor activity and reduce the toxicity of cantharidin. Int J Nanomedicine (2013) 0.79
Synergistic Effect and Molecular Mechanisms of Traditional Chinese Medicine on Regulating Tumor Microenvironment and Cancer Cells. Biomed Res Int (2016) 0.79
Herbal medicines for cancer cachexia: protocol for a systematic review. BMJ Open (2014) 0.79
Herbal extract SH003 suppresses tumor growth and metastasis of MDA-MB-231 breast cancer cells by inhibiting STAT3-IL-6 signaling. Mediators Inflamm (2014) 0.78
Inhibition of autophagy potentiates anticancer property of 20(S)-ginsenoside Rh2 by promoting mitochondria-dependent apoptosis in human acute lymphoblastic leukaemia cells. Oncotarget (2016) 0.77
Glycyrrhetinic Acid Induces Apoptosis in Leukemic HL60 Cells Through Upregulating of CD95/ CD178. Int J Mol Cell Med (2014) 0.75
Folate receptor-targeted liposomes loaded with a diacid metabolite of norcantharidin enhance antitumor potency for H22 hepatocellular carcinoma both in vitro and in vivo. Int J Nanomedicine (2016) 0.75
Ethyl Acetate Extracts of Semen Impatientis Inhibit Proliferation and Induce Apoptosis of Human Prostate Cancer Cell Lines through AKT/ERK Pathways. Biomed Res Int (2017) 0.75
Potent effects of dioscin against pancreatic cancer via miR-149-3P-mediated inhibition of AKT1 signaling pathway. Br J Pharmacol (2017) 0.75
Antitumor effect of a polysaccharide isolated from Phellinus pullus as an immunostimulant. Biomed Rep (2016) 0.75
Apoptotic effect of gambogic acid in esophageal squamous cell carcinoma cells via suppression of the NF-κB pathway. Oncol Lett (2016) 0.75
Effects of Ixeris Chinensis (Thunb.) Nakai boiling water extract on hepatitis B viral activity and hepatocellular carcinoma. Afr J Tradit Complement Altern Med (2013) 0.75
Compounds From Celastraceae Targeting Cancer Pathways and Their Potential Application in Head and Neck Squamous Cell Carcinoma: A Review. Curr Genomics (2017) 0.75
Naringin inhibits lipopolysaccharide-induced damage in human umbilical vein endothelial cells via attenuation of inflammation, apoptosis and MAPK pathways. Cytotechnology (2016) 0.75
A Review of the Potential of Phytochemicals from Prunus africana (Hook f.) Kalkman Stem Bark for Chemoprevention and Chemotherapy of Prostate Cancer. Evid Based Complement Alternat Med (2017) 0.75
Taccaoside induces apoptosis in hepatocellular carcinoma cell lines. J Int Med Res (2016) 0.75
Celastrol: A Spectrum of Treatment Opportunities in Chronic Diseases. Front Med (Lausanne) (2017) 0.75
The renewal and differentiation of Isl1+ cardiovascular progenitors are controlled by a Wnt/beta-catenin pathway. Cell Stem Cell (2007) 3.54
Circulating microRNAs, miR-21, miR-122, and miR-223, in patients with hepatocellular carcinoma or chronic hepatitis. Mol Carcinog (2010) 3.44
A stem cell-based approach to cartilage repair. Science (2012) 3.22
A six-nucleotide insertion-deletion polymorphism in the CASP8 promoter is associated with susceptibility to multiple cancers. Nat Genet (2007) 2.98
Interfering with resistance to smoothened antagonists by inhibition of the PI3K pathway in medulloblastoma. Sci Transl Med (2010) 2.86
A genome-wide association study identifies two new lung cancer susceptibility loci at 13q12.12 and 22q12.2 in Han Chinese. Nat Genet (2011) 2.85
Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974. Proc Natl Acad Sci U S A (2013) 2.49
BarleyBase--an expression profiling database for plant genomics. Nucleic Acids Res (2005) 2.34
Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia. Nat Genet (2012) 2.26
Polymorphisms of death pathway genes FAS and FASL in esophageal squamous-cell carcinoma. J Natl Cancer Inst (2004) 2.22
Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations. Nat Genet (2011) 2.05
Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions. Nat Genet (2012) 2.00
A genome-wide association study identifies new susceptibility loci for non-cardia gastric cancer at 3q13.31 and 5p13.1. Nat Genet (2011) 1.98
Topical treatment of Basal cell carcinomas in nevoid Basal cell carcinoma syndrome with a smoothened inhibitor. J Invest Dermatol (2011) 1.98
Genetic variants on chromosome 15q25 associated with lung cancer risk in Chinese populations. Cancer Res (2009) 1.94
Trend and disease burden of bacillary dysentery in China (1991-2000). Bull World Health Organ (2006) 1.93
Identification of serum-derived sphingosine-1-phosphate as a small molecule regulator of YAP. Chem Biol (2012) 1.91
The 5p15.33 locus is associated with risk of lung adenocarcinoma in never-smoking females in Asia. PLoS Genet (2010) 1.90
A combinatorial scaffold approach toward kinase-directed heterocycle libraries. J Am Chem Soc (2002) 1.79
Glycogen synthase kinase 3 inhibitors induce the canonical WNT/β-catenin pathway to suppress growth and self-renewal in embryonal rhabdomyosarcoma. Proc Natl Acad Sci U S A (2014) 1.79
Genome-wide association study in Chinese men identifies two new prostate cancer risk loci at 9q31.2 and 19q13.4. Nat Genet (2012) 1.78
A small molecule primes embryonic stem cells for differentiation. Cell Stem Cell (2009) 1.78
Polymorphisms in DNA base excision repair genes ADPRT and XRCC1 and risk of lung cancer. Cancer Res (2005) 1.69
Identification of functional genetic variants in cyclooxygenase-2 and their association with risk of esophageal cancer. Gastroenterology (2005) 1.67
In vivo study of biodistribution and urinary excretion of surface-modified silica nanoparticles. Anal Chem (2008) 1.64
The mitochondrial pathway of anesthetic isoflurane-induced apoptosis. J Biol Chem (2009) 1.64
Identification of genetic variants in base excision repair pathway and their associations with risk of esophageal squamous cell carcinoma. Cancer Res (2004) 1.64
Ca2+/calmodulin-dependent protein kinase IIdelta and protein kinase D overexpression reinforce the histone deacetylase 5 redistribution in heart failure. Circ Res (2008) 1.58
The antidiabetic drug metformin inhibits gastric cancer cell proliferation in vitro and in vivo. Mol Cancer Ther (2012) 1.57
Dedifferentiation of lineage-committed cells by a small molecule. J Am Chem Soc (2004) 1.56
Plant DNA barcoding: from gene to genome. Biol Rev Camb Philos Soc (2014) 1.56
The role of P53 and MDM2 polymorphisms in the risk of esophageal squamous cell carcinoma. Cancer Res (2005) 1.56
Association analyses identify multiple new lung cancer susceptibility loci and their interactions with smoking in the Chinese population. Nat Genet (2012) 1.49
Genetic polymorphisms in cell cycle regulatory genes MDM2 and TP53 are associated with susceptibility to lung cancer. Hum Mutat (2006) 1.49
Activatable aptamer probe for contrast-enhanced in vivo cancer imaging based on cell membrane protein-triggered conformation alteration. Proc Natl Acad Sci U S A (2011) 1.48
Functional haplotypes in the promoter of matrix metalloproteinase-2 predict risk of the occurrence and metastasis of esophageal cancer. Cancer Res (2004) 1.46
Genetic polymorphisms and susceptibility to esophageal cancer among Chinese population (review). Oncol Rep (2003) 1.45
A small-molecule agonist of the Wnt signaling pathway. Angew Chem Int Ed Engl (2005) 1.44
Isoflurane-induced caspase-3 activation is dependent on cytosolic calcium and can be attenuated by memantine. J Neurosci (2008) 1.44
Genome-wide association study identifies five loci associated with susceptibility to pancreatic cancer in Chinese populations. Nat Genet (2011) 1.42
A systematic review of the anticancer properties of berberine, a natural product from Chinese herbs. Anticancer Drugs (2009) 1.39
Functional genetic variations in cytotoxic T-lymphocyte antigen 4 and susceptibility to multiple types of cancer. Cancer Res (2008) 1.39
Anesthetic sevoflurane causes neurotoxicity differently in neonatal naïve and Alzheimer disease transgenic mice. Anesthesiology (2010) 1.38
Ganoderma lucidum polysaccharides: immunomodulation and potential anti-tumor activities. Am J Chin Med (2011) 1.36
A meta-analysis of association between C677T polymorphism in the methylenetetrahydrofolate reductase gene and hypertension. Eur J Hum Genet (2007) 1.32
C-terminal peptides coassemble into Abeta42 oligomers and protect neurons against Abeta42-induced neurotoxicity. Proc Natl Acad Sci U S A (2008) 1.32
Functional variants in cell death pathway genes and risk of pancreatic cancer. Clin Cancer Res (2008) 1.31
2',7'-Dichlorodihydrofluorescein as a fluorescent probe for reactive oxygen species measurement: Forty years of application and controversy. Free Radic Res (2010) 1.31
Retracted Epigenetic enhancement of BDNF signaling rescues synaptic plasticity in aging. J Neurosci (2011) 1.30
Risk of genome-wide association study-identified genetic variants for colorectal cancer in a Chinese population. Cancer Epidemiol Biomarkers Prev (2010) 1.29
Compatibility art of traditional Chinese medicine: from the perspective of herb pairs. J Ethnopharmacol (2012) 1.29
Association of candidate genetic variations with gastric cardia adenocarcinoma in Chinese population: a multiple interaction analysis. Carcinogenesis (2010) 1.28
Long-term effectiveness of infancy low-dose hepatitis B vaccine immunization in Zhuang minority area in China. World J Gastroenterol (1999) 1.28
Inhibition of histone deacetylase activity induces developmental plasticity in oligodendrocyte precursor cells. Proc Natl Acad Sci U S A (2007) 1.26
Biological activities and potential molecular targets of cucurbitacins: a focus on cancer. Anticancer Drugs (2012) 1.25
Substantial reduction in risk of lung adenocarcinoma associated with genetic polymorphism in CYP2A13, the most active cytochrome P450 for the metabolic activation of tobacco-specific carcinogen NNK. Cancer Res (2003) 1.25
Perfluorooctanoic acid exposure and pregnancy outcome in a highly exposed community. Epidemiology (2012) 1.22
Identification of RING finger protein 4 (RNF4) as a modulator of DNA demethylation through a functional genomics screen. Proc Natl Acad Sci U S A (2010) 1.22
Identification of small-molecule inducers of pancreatic beta-cell expansion. Proc Natl Acad Sci U S A (2009) 1.20
Genetic polymorphisms in methylenetetrahydrofolate reductase and thymidylate synthase and risk of pancreatic cancer. Clin Gastroenterol Hepatol (2005) 1.20
Core promoter mutations (A(1762)T and G(1764)A) and viral genotype in chronic hepatitis B and hepatocellular carcinoma in Guangxi, China. J Med Virol (2002) 1.20
FASL -844C polymorphism is associated with increased activation-induced T cell death and risk of cervical cancer. J Exp Med (2005) 1.19
TNF-alpha, a potent lipid metabolism regulator. Cell Biochem Funct (2009) 1.18
Nitrous oxide plus isoflurane induces apoptosis and increases beta-amyloid protein levels. Anesthesiology (2009) 1.17
Polymeric micelles drug delivery system in oncology. J Control Release (2012) 1.17
Haplotypes in matrix metalloproteinase gene cluster on chromosome 11q22 contribute to the risk of lung cancer development and progression. Clin Cancer Res (2006) 1.16
Functional polymorphisms in FAS and FASL contribute to increased apoptosis of tumor infiltration lymphocytes and risk of breast cancer. Carcinogenesis (2006) 1.16
Substantial reduction in risk of breast cancer associated with genetic polymorphisms in the promoters of the matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 genes. Carcinogenesis (2003) 1.15
Characterization of gene expression regulated by American ginseng and ginsenoside Rg3 in human colorectal cancer cells. Int J Oncol (2008) 1.15
Polymorphisms of DNA repair genes XRCC1 and XPD and their associations with risk of esophageal squamous cell carcinoma in a Chinese population. Int J Cancer (2002) 1.15
Modeling gene expression networks using fuzzy logic. IEEE Trans Syst Man Cybern B Cybern (2005) 1.14
Methylene blue-encapsulated phosphonate-terminated silica nanoparticles for simultaneous in vivo imaging and photodynamic therapy. Biomaterials (2009) 1.14
Role of CD14 promoter polymorphisms in Helicobacter pylori infection--related gastric carcinoma. Clin Cancer Res (2007) 1.11
Genotypic and phenotypic features of citrin deficiency: five-year experience in a Chinese pediatric center. Int J Mol Med (2011) 1.10
ATM polymorphisms are associated with risk of radiation-induced pneumonitis. Int J Radiat Oncol Biol Phys (2010) 1.10
Correlation between a single nucleotide polymorphism in the matrix metalloproteinase-2 promoter and risk of lung cancer. Cancer Res (2002) 1.10
Overexpression and hypomethylation of flap endonuclease 1 gene in breast and other cancers. Mol Cancer Res (2008) 1.10
A functional polymorphism in the matrix metalloproteinase-2 gene promoter (-1306C/T) is associated with risk of development but not metastasis of gastric cardia adenocarcinoma. Cancer Res (2003) 1.09
Functional FEN1 polymorphisms are associated with DNA damage levels and lung cancer risk. Hum Mutat (2009) 1.08
Genetic variation in an miRNA-1827 binding site in MYCL1 alters susceptibility to small-cell lung cancer. Cancer Res (2011) 1.08
Sequence variations in the DNA repair gene XPD and risk of lung cancer in a Chinese population. Int J Cancer (2003) 1.07
Ganoderic acid DM, a natural triterpenoid, induces DNA damage, G1 cell cycle arrest and apoptosis in human breast cancer cells. Fitoterapia (2011) 1.06
Chinese herbal medicine-derived compounds for cancer therapy: a focus on hepatocellular carcinoma. J Ethnopharmacol (2013) 1.06
Evidence of associations of APOBEC3B gene deletion with susceptibility to persistent HBV infection and hepatocellular carcinoma. Hum Mol Genet (2012) 1.05
Genome-wide association study of prognosis in advanced non-small cell lung cancer patients receiving platinum-based chemotherapy. Clin Cancer Res (2012) 1.05
Two genetic variants in prostate stem cell antigen and gastric cancer susceptibility in a Chinese population. Mol Carcinog (2009) 1.05
Functional STK15 Phe31Ile polymorphism is associated with the occurrence and advanced disease status of esophageal squamous cell carcinoma. Cancer Res (2004) 1.04
Association of P53 and ATM polymorphisms with risk of radiation-induced pneumonitis in lung cancer patients treated with radiotherapy. Int J Radiat Oncol Biol Phys (2010) 1.04
Genome-wide association study identifies common variants in SLC39A6 associated with length of survival in esophageal squamous-cell carcinoma. Nat Genet (2013) 1.04
A genomic screen identifies TYRO3 as a MITF regulator in melanoma. Proc Natl Acad Sci U S A (2009) 1.04
Susceptibility to gastric cardia adenocarcinoma and genetic polymorphisms in methylenetetrahydrofolate reductase in an at-risk Chinese population. Cancer Epidemiol Biomarkers Prev (2002) 1.03
DNA repair gene XPC genotypes/haplotypes and risk of lung cancer in a Chinese population. Int J Cancer (2005) 1.03
Interaction of P53 Arg72Pro and MDM2 T309G polymorphisms and their associations with risk of gastric cardia cancer. Carcinogenesis (2007) 1.03
Small-molecule inducer of β cell proliferation identified by high-throughput screening. J Am Chem Soc (2013) 1.02