Published in Cell Host Microbe on January 26, 2012
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A first-in-class NAE inhibitor, MLN4924, blocks lentiviral infection in myeloid cells by disrupting neddylation-dependent Vpx-mediated SAMHD1 degradation. J Virol (2013) 0.86
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G2/M cell cycle arrest correlates with primate lentiviral Vpr interaction with the SLX4 complex. J Virol (2014) 0.86
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Macrophages in Progressive Human Immunodeficiency Virus/Simian Immunodeficiency Virus Infections. J Virol (2016) 0.78
Interactions with DCAF1 and DDB1 in the CRL4 E3 ubiquitin ligase are required for Vpr-mediated G2 arrest. Virol J (2014) 0.78
HIV-1 Vpr reactivates latent HIV-1 provirus by inducing depletion of class I HDACs on chromatin. Sci Rep (2016) 0.78
SAMHD1 transcript upregulation during SIV infection of the central nervous system does not associate with reduced viral load. Sci Rep (2016) 0.78
SLX4-SLX1 Protein-independent Down-regulation of MUS81-EME1 Protein by HIV-1 Viral Protein R (Vpr). J Biol Chem (2016) 0.78
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The susceptibility of primate lentiviruses to nucleosides and Vpx during infection of dendritic cells is regulated by CA. J Virol (2015) 0.77
Effects of human SAMHD1 polymorphisms on HIV-1 susceptibility. Virology (2014) 0.77
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Degradation of SAMHD1 by Vpx Is Independent of Uncoating. J Virol (2015) 0.76
Phylogenetic Insights into the Functional Relationship between Primate Lentiviral Reverse Transcriptase and Accessory Proteins Vpx/Vpr. Front Microbiol (2016) 0.76
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Non-human Primate Schlafen11 Inhibits Production of Both Host and Viral Proteins. PLoS Pathog (2016) 0.75
SAMHD1 enhances nucleoside-analogue efficacy against HIV-1 in myeloid cells. Sci Rep (2017) 0.75
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