ARID5B genetic polymorphisms contribute to racial disparities in the incidence and treatment outcome of childhood acute lymphoblastic leukemia.

PubWeight™: 1.39‹?› | Rank: Top 5%

🔗 View Article (PMC 3295551)

Published in J Clin Oncol on January 30, 2012


Heng Xu1, Cheng Cheng, Meenakshi Devidas, Deqing Pei, Yiping Fan, Wenjian Yang, Geoff Neale, Paul Scheet, Esteban G Burchard, Dara G Torgerson, Celeste Eng, Michael Dean, Frederico Antillon, Naomi J Winick, Paul L Martin, Cheryl L Willman, Bruce M Camitta, Gregory H Reaman, William L Carroll, Mignon Loh, William E Evans, Ching-Hon Pui, Stephen P Hunger, Mary V Relling, Jun J Yang

Author Affiliations

1: St. Jude Children’s Research Hospital, Memphis, TN 38105-3678, USA.

Associated clinical trials:

Therapy for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia | NCT00137111

Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia | NCT00005596

Combination Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia | NCT00005585

Articles citing this

Acute lymphoblastic leukaemia. Lancet (2013) 3.44

Pediatric acute lymphoblastic leukemia: where are we going and how do we get there? Blood (2012) 2.82

Novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populations. J Natl Cancer Inst (2013) 1.81

Inherited GATA3 variants are associated with Ph-like childhood acute lymphoblastic leukemia and risk of relapse. Nat Genet (2013) 1.45

Associations between genome-wide Native American ancestry, known risk alleles and B-cell ALL risk in Hispanic children. Leukemia (2013) 1.33

A 50-year journey to cure childhood acute lymphoblastic leukemia. Semin Hematol (2013) 1.32

Children's Oncology Group's 2013 blueprint for research: acute lymphoblastic leukemia. Pediatr Blood Cancer (2012) 1.29

Genome-wide study of methotrexate clearance replicates SLCO1B1. Blood (2012) 1.17

Racial/Ethnic Differences in Pediatric Brain Tumor Diagnoses in Patients with Neurofibromatosis Type 1. J Pediatr (2015) 1.15

Inherited genetic variation in childhood acute lymphoblastic leukemia. Blood (2015) 1.09

Management of adult and paediatric acute lymphoblastic leukaemia in Asia: resource-stratified guidelines from the Asian Oncology Summit 2013. Lancet Oncol (2013) 1.07

Toward the Cure of All Children With Cancer Through Collaborative Efforts: Pediatric Oncology As a Global Challenge. J Clin Oncol (2015) 1.06

A genome-wide association study of susceptibility to acute lymphoblastic leukemia in adolescents and young adults. Blood (2014) 1.04

Genetic variants in ARID5B and CEBPE are childhood ALL susceptibility loci in Hispanics. Cancer Causes Control (2013) 0.97

Genomics of racial and ethnic disparities in childhood acute lymphoblastic leukemia. Cancer (2013) 0.96

Genomic ancestry and somatic alterations correlate with age at diagnosis in Hispanic children with B-cell acute lymphoblastic leukemia. Am J Hematol (2014) 0.92

Analysis of Patterns of Gene Expression Variation within and between Ethnic Populations in Pediatric B-ALL. Cancer Inform (2013) 0.88

A new system identification approach to identify genetic variants in sequencing studies for a binary phenotype. Hum Hered (2014) 0.87

Biologic and clinical characteristics of adolescent and young adult cancers: Acute lymphoblastic leukemia, colorectal cancer, breast cancer, melanoma, and sarcoma. Cancer (2016) 0.85

Genetic susceptibility in childhood acute leukaemias: a systematic review. Ecancermedicalscience (2015) 0.85

ARID5B and IKZF1 variants, selected demographic factors, and childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group. Leuk Res (2013) 0.82

Intron 3 of the ARID5B gene: a hot spot for acute lymphoblastic leukemia susceptibility. J Cancer Res Clin Oncol (2013) 0.82

Survival of Mexican Children with Acute Lymphoblastic Leukaemia under Treatment with the Protocol from the Dana-Farber Cancer Institute 00-01. Biomed Res Int (2015) 0.79

Germline variants in IKZF1, ARID5B, and CEBPE as risk factors for adult-onset acute lymphoblastic leukemia: an analysis from the GMALL study group. Haematologica (2014) 0.78

Asparaginase treatment side-effects may be due to genes with homopolymeric Asn codons (Review-Hypothesis). Int J Mol Med (2015) 0.76

Host genetic variants of ABCB1 and IL15 influence treatment outcome in paediatric acute lymphoblastic leukaemia. Br J Cancer (2014) 0.76

Multi-agent chemotherapy overcomes glucocorticoid resistance conferred by a BIM deletion polymorphism in pediatric acute lymphoblastic leukemia. PLoS One (2014) 0.76

Association Between PIP4K2A Polymorphisms and Acute Lymphoblastic Leukemia Susceptibility. Medicine (Baltimore) (2016) 0.75

Impact of NUDT15 polymorphisms on thiopurines-induced myelotoxicity and thiopurines tolerance dose. Oncotarget (2017) 0.75

Maternal prenatal intake of one-carbon metabolism nutrients and risk of childhood leukemia. Cancer Causes Control (2016) 0.75

Molecular studies reveal MLL-MLLT10/AF10 and ARID5B-MLL gene fusions displaced in a case of infantile acute lymphoblastic leukemia with complex karyotype. Oncol Lett (2017) 0.75

Articles cited by this

Inference of population structure using multilocus genotype data. Genetics (2000) 147.76

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature (2009) 33.26

Worldwide human relationships inferred from genome-wide patterns of variation. Science (2008) 22.44

Integrated genotype calling and association analysis of SNPs, common copy number polymorphisms and rare CNVs. Nat Genet (2008) 15.89

Treatment of acute lymphoblastic leukemia. N Engl J Med (2006) 11.30

Support from the relationship of genetic and geographic distance in human populations for a serial founder effect originating in Africa. Proc Natl Acad Sci U S A (2005) 10.22

Common variants on chromosome 6p22.1 are associated with schizophrenia. Nature (2009) 8.12

Estimating local ancestry in admixed populations. Am J Hum Genet (2008) 5.90

Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia and its relationship to other prognostic factors: a Children's Oncology Group study. Blood (2008) 5.49

Ancestry and pharmacogenomics of relapse in acute lymphoblastic leukemia. Nat Genet (2011) 4.93

Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia. Nat Genet (2009) 4.47

A genomewide admixture mapping panel for Hispanic/Latino populations. Am J Hum Genet (2007) 3.85

Trends in childhood cancer incidence in the U.S. (1992-2004). Cancer (2008) 3.71

Germline genomic variants associated with childhood acute lymphoblastic leukemia. Nat Genet (2009) 3.71

Survival variability by race and ethnicity in childhood acute lymphoblastic leukemia. JAMA (2003) 3.07

Results of therapy for acute lymphoblastic leukemia in black and white children. JAMA (2003) 2.77

Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia. JAMA (2009) 2.72

Racial differences in the survival of childhood B-precursor acute lymphoblastic leukemia: a Pediatric Oncology Group Study. J Clin Oncol (2000) 2.40

Lower bronchodilator responsiveness in Puerto Rican than in Mexican subjects with asthma. Am J Respir Crit Care Med (2003) 2.39

Environmental and genetic risk factors for childhood leukemia: appraising the evidence. Cancer Invest (2005) 2.36

Racial and ethnic differences in survival of children with acute lymphoblastic leukemia. Blood (2002) 2.17

SEER update of incidence and trends in pediatric malignancies: acute lymphoblastic leukemia. Med Pediatr Oncol (2002) 2.13

Genome-wide association study of childhood acute lymphoblastic leukemia in Korea. Leuk Res (2010) 1.85

Verification of the susceptibility loci on 7p12.2, 10q21.2, and 14q11.2 in precursor B-cell acute lymphoblastic leukemia of childhood. Blood (2009) 1.64

ARID5B SNP rs10821936 is associated with risk of childhood acute lymphoblastic leukemia in blacks and contributes to racial differences in leukemia incidence. Leukemia (2010) 1.34

Candidate gene association studies and risk of childhood acute lymphoblastic leukemia: a systematic review and meta-analysis. Haematologica (2010) 1.33

A systematic literature review of the clinical and epidemiological burden of acute lymphoblastic leukaemia (ALL). Eur J Cancer Care (Engl) (2005) 1.25

Replication analysis confirms the association of ARID5B with childhood B-cell acute lymphoblastic leukemia. Haematologica (2010) 1.20

Genome-wide association study SNPs in the human genome diversity project populations: does selection affect unlinked SNPs with shared trait associations? PLoS Genet (2011) 1.17

Disparities in cancer outcomes: lessons learned from children with cancer. Pediatr Blood Cancer (2011) 1.15

Variation at 7p12.2 and 10q21.2 influences childhood acute lymphoblastic leukemia risk in the Thai population and may contribute to racial differences in leukemia incidence. Leuk Lymphoma (2010) 1.14

Influence of race and socioeconomic status on outcome of children treated for childhood acute lymphoblastic leukemia. Curr Opin Pediatr (2004) 1.14

Folate related gene polymorphisms and susceptibility to develop childhood acute lymphoblastic leukaemia. Br J Haematol (2009) 1.10

Childhood cancer in relation to parental race and ethnicity: a 5-state pooled analysis. Cancer (2010) 0.99

Genetic susceptibility to childhood leukaemia. Radiat Prot Dosimetry (2008) 0.88

Molecular and epidemiologic findings of childhood acute leukemia in Costa Rica. J Pediatr Hematol Oncol (2009) 0.78

Articles by these authors

MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes. Genet Epidemiol (2010) 26.41

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35

Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet (2008) 20.66

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89

Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia. Nature (2007) 17.68

Revised recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia. J Clin Oncol (2003) 17.67

Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet (2008) 15.94

Accounting for decay of linkage disequilibrium in haplotype inference and missing-data imputation. Am J Hum Genet (2005) 14.09

A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration. Proc Natl Acad Sci U S A (2005) 13.44

The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell (2003) 12.50

Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet (2009) 12.44

Genotype, haplotype and copy-number variation in worldwide human populations. Nature (2008) 12.40

Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling. Cancer Cell (2002) 11.83

Treatment of acute lymphoblastic leukemia. N Engl J Med (2006) 11.30

Variants in MTNR1B influence fasting glucose levels. Nat Genet (2008) 10.85

Retracted Detection of an infectious retrovirus, XMRV, in blood cells of patients with chronic fatigue syndrome. Science (2009) 10.76

Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia. N Engl J Med (2009) 10.54

BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros. Nature (2008) 10.12

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia. Nature (2012) 9.89

Large-scale sequence analysis of avian influenza isolates. Science (2006) 9.87

Automating sequence-based detection and genotyping of SNPs from diploid samples. Nat Genet (2006) 9.04

Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nat Genet (2010) 8.55

Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration. Nat Genet (2006) 8.33

Treating childhood acute lymphoblastic leukemia without cranial irradiation. N Engl J Med (2009) 7.95

Acute lymphoblastic leukemia. N Engl J Med (2004) 7.83

Genotype-imputation accuracy across worldwide human populations. Am J Hum Genet (2009) 7.28

Age and acute myeloid leukemia. Blood (2006) 6.46

The genome of the sea urchin Strongylocentrotus purpuratus. Science (2006) 6.41

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet (2009) 5.81

Single-cell exome sequencing reveals single-nucleotide mutation characteristics of a kidney tumor. Cell (2012) 5.62

Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia and its relationship to other prognostic factors: a Children's Oncology Group study. Blood (2008) 5.49

Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia. N Engl J Med (2014) 5.37

A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study. Lancet Oncol (2009) 5.22

Outcomes for children and adolescents with cancer: challenges for the twenty-first century. J Clin Oncol (2010) 5.11

Improved survival for children and adolescents with acute lymphoblastic leukemia between 1990 and 2005: a report from the children's oncology group. J Clin Oncol (2012) 5.08

A novel retinoblastoma therapy from genomic and epigenetic analyses. Nature (2012) 5.02

JAK mutations in high-risk childhood acute lymphoblastic leukemia. Proc Natl Acad Sci U S A (2009) 4.98

Ancestry and pharmacogenomics of relapse in acute lymphoblastic leukemia. Nat Genet (2011) 4.93

Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia. Lancet Oncol (2009) 4.89