Filaggrin loss-of-function mutations are associated with enhanced expression of IL-1 cytokines in the stratum corneum of patients with atopic dermatitis and in a murine model of filaggrin deficiency.

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Published in J Allergy Clin Immunol on February 08, 2012

Authors

Sanja Kezic1, Gráinne M O'Regan, René Lutter, Ivone Jakasa, Ellen S Koster, Sean Saunders, Peter Caspers, Patrick M J H Kemperman, Gerwin J Puppels, Aileen Sandilands, Huijia Chen, Linda E Campbell, Karin Kroboth, Rosemarie Watson, Padraic G Fallon, W H Irwin McLean, Alan D Irvine

Author Affiliations

1: Coronel Institute of Occupational Health, Academic Medical Center, Amsterdam, the Netherlands.

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