Aging and stress: past hypotheses, present approaches and perspectives.

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Published in Aging Dis on January 28, 2011

Authors

Pedro Garrido1

Author Affiliations

1: Department of Physiology, Faculty of Medicine, Universidad Complutense, 28040 Madrid, Spain.

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Translating the histone code. Science (2001) 56.77

Epigenetic programming by maternal behavior. Nat Neurosci (2004) 20.92

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Accelerated telomere shortening in response to life stress. Proc Natl Acad Sci U S A (2004) 12.89

Extending healthy life span--from yeast to humans. Science (2010) 12.12

Physiology and neurobiology of stress and adaptation: central role of the brain. Physiol Rev (2007) 11.15

Effects of stress throughout the lifespan on the brain, behaviour and cognition. Nat Rev Neurosci (2009) 11.02

More hippocampal neurons in adult mice living in an enriched environment. Nature (1997) 10.06

The concept of allostasis in biology and biomedicine. Horm Behav (2003) 9.37

Be smart, exercise your heart: exercise effects on brain and cognition. Nat Rev Neurosci (2008) 8.69

Cognitive reserve. Neuropsychologia (2009) 8.41

Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action. Nat Neurosci (2006) 8.24

Neural consequences of environmental enrichment. Nat Rev Neurosci (2000) 6.79

Altered histone acetylation is associated with age-dependent memory impairment in mice. Science (2010) 6.38

Participation in cognitively stimulating activities and risk of incident Alzheimer disease. JAMA (2002) 6.18

Neural regulation of endocrine and autonomic stress responses. Nat Rev Neurosci (2009) 6.12

Smaller hippocampal volume predicts pathologic vulnerability to psychological trauma. Nat Neurosci (2002) 5.45

Chronic stress induces contrasting patterns of dendritic remodeling in hippocampal and amygdaloid neurons. J Neurosci (2002) 5.44

Brain corticosteroid receptor balance in health and disease. Endocr Rev (1998) 5.27

Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses. Epigenetics (2008) 4.96

Cortisol levels during human aging predict hippocampal atrophy and memory deficits. Nat Neurosci (1998) 4.76

Central mechanisms of stress integration: hierarchical circuitry controlling hypothalamo-pituitary-adrenocortical responsiveness. Front Neuroendocrinol (2003) 4.70

Neural plasticity in the ageing brain. Nat Rev Neurosci (2006) 4.66

Stress, memory and the amygdala. Nat Rev Neurosci (2009) 4.57

Life and death of neurons in the aging brain. Science (1997) 4.52

The neurobiology of stress: from serendipity to clinical relevance. Brain Res (2000) 4.51

The neuroendocrinology of stress and aging: the glucocorticoid cascade hypothesis. Endocr Rev (1986) 4.21

Lasting epigenetic influence of early-life adversity on the BDNF gene. Biol Psychiatry (2009) 4.12

Two receptor systems for corticosterone in rat brain: microdistribution and differential occupation. Endocrinology (1985) 4.11

Adrenocortical hormones in human plasma. J Biol Chem (1953) 3.84

The neuropsychopharmacology of fronto-executive function: monoaminergic modulation. Annu Rev Neurosci (2009) 3.79

Psychobiology and molecular genetics of resilience. Nat Rev Neurosci (2009) 3.71

Limbic system mechanisms of stress regulation: hypothalamo-pituitary-adrenocortical axis. Prog Neuropsychopharmacol Biol Psychiatry (2005) 3.61

Neural mechanisms of ageing and cognitive decline. Nature (2010) 3.59

The role of the medial prefrontal cortex (cingulate gyrus) in the regulation of hypothalamic-pituitary-adrenal responses to stress. J Neurosci (1993) 3.47

The role of the hippocampus in feedback regulation of the hypothalamic-pituitary-adrenocortical axis. Endocr Rev (1991) 3.37

Chronic stress causes frontostriatal reorganization and affects decision-making. Science (2009) 3.36

Stress and glucocorticoids impair retrieval of long-term spatial memory. Nature (1998) 3.28

The effects of stress and stress hormones on human cognition: Implications for the field of brain and cognition. Brain Cogn (2007) 3.18

Chronic behavioral stress induces apical dendritic reorganization in pyramidal neurons of the medial prefrontal cortex. Neuroscience (2004) 3.06

Depressed mood and the incidence of Alzheimer's disease in the elderly living in the community. Arch Gen Psychiatry (1996) 2.99

Stress-induced atrophy of apical dendrites of hippocampal CA3c neurons: involvement of glucocorticoid secretion and excitatory amino acid receptors. Neuroscience (1995) 2.97

Exposure to excess glucocorticoids alters dendritic morphology of adult hippocampal pyramidal neurons. Brain Res (1990) 2.96

Repeated restraint stress facilitates fear conditioning independently of causing hippocampal CA3 dendritic atrophy. Behav Neurosci (1999) 2.81

Cognitive activity and incident AD in a population-based sample of older persons. Neurology (2002) 2.77

Differential effect of stress on in vivo dopamine release in striatum, nucleus accumbens, and medial frontal cortex. J Neurochem (1989) 2.75

HPA axis responses to laboratory psychosocial stress in healthy elderly adults, younger adults, and children: impact of age and gender. Psychoneuroendocrinology (2004) 2.68

Stress duration modulates the spatiotemporal patterns of spine formation in the basolateral amygdala. Proc Natl Acad Sci U S A (2005) 2.59

Reorganization of the morphology of hippocampal neurites and synapses after stress-induced damage correlates with behavioral improvement. Neuroscience (2000) 2.54

Hippocampal formation volume, memory dysfunction, and cortisol levels in patients with Cushing's syndrome. Biol Psychiatry (1992) 2.51

Postnatal developmental profile of brain-derived neurotrophic factor in rat brain and platelets. Neurosci Lett (2002) 2.51

Dendritic reorganization in pyramidal neurons in medial prefrontal cortex after chronic corticosterone administration. J Neurobiol (2001) 2.50

Preserved neuron number in the hippocampus of aged rats with spatial learning deficits. Proc Natl Acad Sci U S A (1996) 2.46

Prolonged glucocorticoid exposure reduces hippocampal neuron number: implications for aging. J Neurosci (1985) 2.34

Education, activity, health, blood pressure and apolipoprotein E as predictors of cognitive change in old age: a review. Gerontology (2000) 2.28

Emotional perseveration: an update on prefrontal-amygdala interactions in fear extinction. Learn Mem (2004) 2.23

Predictors of maintaining cognitive function in older adults: the Health ABC study. Neurology (2009) 2.21

Stress and memory: behavioral effects and neurobiological mechanisms. Neural Plast (2007) 2.10

Brain plasticity and functional losses in the aged: scientific bases for a novel intervention. Prog Brain Res (2006) 2.09

Adrenal steroid receptors and actions in the nervous system. Physiol Rev (1986) 2.07

Selective retention of corticosterone by limbic structures in rat brain. Nature (1968) 2.05

Environmental influences on cognitive and brain plasticity during aging. J Gerontol A Biol Sci Med Sci (2004) 1.99

Glucocorticoids, stress, and their adverse neurological effects: relevance to aging. Exp Gerontol (1999) 1.98

Genetics of aging in Caenorhabditis elegans. PLoS Genet (2007) 1.97

Regional differentiation of the medial prefrontal cortex in regulating adaptive responses to acute emotional stress. J Neurosci (2006) 1.94

Brain-derived neurotrophic factor is associated with age-related decline in hippocampal volume. J Neurosci (2010) 1.90

Reversibility of apical dendritic retraction in the rat medial prefrontal cortex following repeated stress. Exp Neurol (2005) 1.89

Glucocorticoid-sensitive hippocampal neurons are involved in terminating the adrenocortical stress response. Proc Natl Acad Sci U S A (1984) 1.85

A meta-analysis of cortisol response to challenge in human aging: importance of gender. Psychoneuroendocrinology (2005) 1.79

Stress preferentially increases extraneuronal levels of excitatory amino acids in the prefrontal cortex: comparison to hippocampus and basal ganglia. J Neurochem (1993) 1.78

Brain function and chromatin plasticity. Nature (2010) 1.75

Acute corticosterone treatment is sufficient to induce anxiety and amygdaloid dendritic hypertrophy. Proc Natl Acad Sci U S A (2008) 1.75

Regulation of hippocampal H3 histone methylation by acute and chronic stress. Proc Natl Acad Sci U S A (2009) 1.72

Genetic determinants of human health span and life span: progress and new opportunities. PLoS Genet (2007) 1.70

Structural and functional alterations to rat medial prefrontal cortex following chronic restraint stress and recovery. Neuroscience (2009) 1.68

Cognitive and physical activity differently modulate disease progression in the amyloid precursor protein (APP)-23 model of Alzheimer's disease. Biol Psychiatry (2006) 1.66

Decrease in cortisol reverses human hippocampal atrophy following treatment of Cushing's disease. Biol Psychiatry (1999) 1.66

Mechanisms for acute stress-induced enhancement of glutamatergic transmission and working memory. Mol Psychiatry (2010) 1.66

Membrane-associated glucocorticoid activity is necessary for modulation of long-term memory via chromatin modification. J Neurosci (2010) 1.65

Enduring effects of chronic corticosterone treatment on spatial learning, synaptic plasticity, and hippocampal neuropathology in young and mid-aged rats. J Neurosci (1995) 1.63

Age-related changes in Arc transcription and DNA methylation within the hippocampus. Neurobiol Aging (2010) 1.61

Brain aging correlates: retardation by hormonal-pharmacological treatments. Science (1981) 1.61

Gender differences in age-related changes in HPA axis reactivity. Psychoneuroendocrinology (2001) 1.60

Epigenetic codes in cognition and behaviour. Behav Brain Res (2008) 1.56

Selective activation of mesocortical DA system by stress. Nature (1976) 1.56

Characterization of hippocampal norepinephrine release as measured by microdialysis perfusion: pharmacological and behavioral studies. Neuroscience (1988) 1.54

11Beta-hydroxysteroid dehydrogenase inhibition improves cognitive function in healthy elderly men and type 2 diabetics. Proc Natl Acad Sci U S A (2004) 1.52

Hypothalamic-pituitary-adrenal activity in aged, cognitively impaired and cognitively unimpaired rats. J Neurosci (1990) 1.51

Hippocampal aging and adrenocorticoids: quantitative correlations. Science (1978) 1.50

Evidence for hippocampal regulation of neuroendocrine neurons of the hypothalamo-pituitary-adrenocortical axis. J Neurosci (1989) 1.50

Chronic stress-induced hippocampal vulnerability: the glucocorticoid vulnerability hypothesis. Rev Neurosci (2008) 1.49

Environmental enrichment requires adult neurogenesis to facilitate the recovery from psychosocial stress. Mol Psychiatry (2010) 1.47

The neuroendocrinology of stress: a never ending story. J Neuroendocrinol (2008) 1.45

Penetration of endogenous steroid hormones corticosterone, cortisol, aldosterone and progesterone into the brain is enhanced in mice deficient for both mdr1a and mdr1b P-glycoproteins. J Neuroendocrinol (2002) 1.41

Aging, plasticity and environmental enrichment: structural changes and neurotransmitter dynamics in several areas of the brain. Brain Res Rev (2007) 1.41

Lifelong corticosterone level determines age-related decline in neurogenesis and memory. Neurobiol Aging (2005) 1.39

Rapid glucocorticoid effects on excitatory amino acid levels in the hippocampus: a microdialysis study in freely moving rats. Eur J Neurosci (1999) 1.39

Memory: brain systems and behavior. Trends Neurosci (1988) 1.39

Human models in acute and chronic stress: assessing determinants of individual hypothalamus-pituitary-adrenal axis activity and reactivity. Stress (2010) 1.38

Role of the amygdala in the coordination of behavioral, neuroendocrine, and prefrontal cortical monoamine responses to psychological stress in the rat. J Neurosci (1996) 1.38